{"id":"https://openalex.org/W2781351714","doi":"https://doi.org/10.1186/s12911-017-0561-y","title":"Substance deposition assessment in obstructed pulmonary system through numerical characterization of airflow and inhaled particles attributes","display_name":"Substance deposition assessment in obstructed pulmonary system through numerical characterization of airflow and inhaled particles attributes","publication_year":2017,"publication_date":"2017-12-01","ids":{"openalex":"https://openalex.org/W2781351714","doi":"https://doi.org/10.1186/s12911-017-0561-y","mag":"2781351714","pmid":"https://pubmed.ncbi.nlm.nih.gov/29297393"},"language":"en","primary_location":{"id":"doi:10.1186/s12911-017-0561-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-017-0561-y","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-017-0561-y","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-017-0561-y","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051582957","display_name":"Antonios Lalas","orcid":"https://orcid.org/0000-0002-5337-161X"},"institutions":[{"id":"https://openalex.org/I4210093649","display_name":"Information Technologies Institute","ror":"https://ror.org/0069akp70","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093649"]},{"id":"https://openalex.org/I4210134249","display_name":"Centre for Research and Technology Hellas","ror":"https://ror.org/03bndpq63","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210134249"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Antonios Lalas","raw_affiliation_strings":["Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece. lalas@iti.gr","Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece. lalas@iti.gr","institution_ids":[]},{"raw_affiliation_string":"Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece","institution_ids":["https://openalex.org/I4210093649","https://openalex.org/I4210134249"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061959060","display_name":"Stavros Nousias","orcid":"https://orcid.org/0000-0002-2811-235X"},"institutions":[{"id":"https://openalex.org/I174878644","display_name":"University of Patras","ror":"https://ror.org/017wvtq80","country_code":"GR","type":"education","lineage":["https://openalex.org/I174878644"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Stavros Nousias","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Patras, Patra, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Patras, Patra, Greece","institution_ids":["https://openalex.org/I174878644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001128222","display_name":"Dimitrios Kikidis","orcid":"https://orcid.org/0000-0002-1445-5474"},"institutions":[{"id":"https://openalex.org/I4210134249","display_name":"Centre for Research and Technology Hellas","ror":"https://ror.org/03bndpq63","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210134249"]},{"id":"https://openalex.org/I4210093649","display_name":"Information Technologies Institute","ror":"https://ror.org/0069akp70","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093649"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Dimitrios Kikidis","raw_affiliation_strings":["Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece","institution_ids":["https://openalex.org/I4210093649","https://openalex.org/I4210134249"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086877328","display_name":"Aris S. Lalos","orcid":"https://orcid.org/0000-0003-0511-9302"},"institutions":[{"id":"https://openalex.org/I174878644","display_name":"University of Patras","ror":"https://ror.org/017wvtq80","country_code":"GR","type":"education","lineage":["https://openalex.org/I174878644"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Aris Lalos","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Patras, Patra, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Patras, Patra, Greece","institution_ids":["https://openalex.org/I174878644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003278899","display_name":"Gerasimos Arvanitis","orcid":"https://orcid.org/0000-0001-8149-5188"},"institutions":[{"id":"https://openalex.org/I174878644","display_name":"University of Patras","ror":"https://ror.org/017wvtq80","country_code":"GR","type":"education","lineage":["https://openalex.org/I174878644"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Gerasimos Arvanitis","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Patras, Patra, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Patras, Patra, Greece","institution_ids":["https://openalex.org/I174878644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013814788","display_name":"Christos Sougles","orcid":null},"institutions":[{"id":"https://openalex.org/I4210134249","display_name":"Centre for Research and Technology Hellas","ror":"https://ror.org/03bndpq63","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210134249"]},{"id":"https://openalex.org/I4210093649","display_name":"Information Technologies Institute","ror":"https://ror.org/0069akp70","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093649"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Christos Sougles","raw_affiliation_strings":["Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece","institution_ids":["https://openalex.org/I4210093649","https://openalex.org/I4210134249"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109963015","display_name":"\u039a\u03c9\u03bd\u03c3\u03c4\u03b1\u03bd\u03c4\u03af\u03bd\u03bf\u03c2 \u039c\u03bf\u03c5\u03c3\u03c4\u03ac\u03ba\u03b1\u03c2","orcid":"https://orcid.org/0000-0001-7617-227X"},"institutions":[{"id":"https://openalex.org/I174878644","display_name":"University of Patras","ror":"https://ror.org/017wvtq80","country_code":"GR","type":"education","lineage":["https://openalex.org/I174878644"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Konstantinos Moustakas","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Patras, Patra, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Patras, Patra, Greece","institution_ids":["https://openalex.org/I174878644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064307246","display_name":"Konstantinos Votis","orcid":"https://orcid.org/0000-0001-6381-8326"},"institutions":[{"id":"https://openalex.org/I4210134249","display_name":"Centre for Research and Technology Hellas","ror":"https://ror.org/03bndpq63","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210134249"]},{"id":"https://openalex.org/I4210093649","display_name":"Information Technologies Institute","ror":"https://ror.org/0069akp70","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093649"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Konstantinos Votis","raw_affiliation_strings":["Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece","institution_ids":["https://openalex.org/I4210093649","https://openalex.org/I4210134249"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034739519","display_name":"Sylvia Verbanck","orcid":"https://orcid.org/0000-0003-0231-2756"},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Sylvia Verbanck","raw_affiliation_strings":["Respiratory Division, University Hospital UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Respiratory Division, University Hospital UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium","institution_ids":["https://openalex.org/I13469542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059657782","display_name":"Omar S. Usmani","orcid":"https://orcid.org/0000-0002-4367-254X"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I4210096640","display_name":"Royal Brompton Hospital","ror":"https://ror.org/00cv4n034","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800036501","https://openalex.org/I4210096640"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Omar Usmani","raw_affiliation_strings":["National Heart and Lung Institute (NHLI), Imperial College London and Royal Brompton Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Heart and Lung Institute (NHLI), Imperial College London and Royal Brompton Hospital, London, UK","institution_ids":["https://openalex.org/I4210096640","https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087452615","display_name":"Dimitrios Tzovaras","orcid":"https://orcid.org/0000-0001-6915-6722"},"institutions":[{"id":"https://openalex.org/I4210134249","display_name":"Centre for Research and Technology Hellas","ror":"https://ror.org/03bndpq63","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210134249"]},{"id":"https://openalex.org/I4210093649","display_name":"Information Technologies Institute","ror":"https://ror.org/0069akp70","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093649"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Dimitrios Tzovaras","raw_affiliation_strings":["Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Information Technologies Institute, Centre for Research and Technology - Hellas (CERTH), Thessaloniki, Greece","institution_ids":["https://openalex.org/I4210093649","https://openalex.org/I4210134249"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5051582957"],"corresponding_institution_ids":["https://openalex.org/I4210093649","https://openalex.org/I4210134249"],"apc_list":{"value":1570,"currency":"GBP","value_usd":1925},"apc_paid":{"value":1570,"currency":"GBP","value_usd":1925},"fwci":0.4103,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.69458483,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"17","issue":"S3","first_page":"173","last_page":"173"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11651","display_name":"Inhalation and Respiratory Drug Delivery","score":0.9200000166893005,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11651","display_name":"Inhalation and Respiratory Drug Delivery","score":0.9200000166893005,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12350","display_name":"Particle Dynamics in Fluid Flows","score":0.029100000858306885,"subfield":{"id":"https://openalex.org/subfields/2212","display_name":"Ocean Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11751","display_name":"Lattice Boltzmann Simulation Studies","score":0.00930000003427267,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/copd","display_name":"COPD","score":0.6508665680885315},{"id":"https://openalex.org/keywords/particle-deposition","display_name":"Particle deposition","score":0.5565035939216614},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.548849880695343},{"id":"https://openalex.org/keywords/lung","display_name":"Lung","score":0.5259459614753723},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5174737572669983},{"id":"https://openalex.org/keywords/airflow","display_name":"Airflow","score":0.4912559390068054},{"id":"https://openalex.org/keywords/asthma","display_name":"Asthma","score":0.48229268193244934},{"id":"https://openalex.org/keywords/computational-fluid-dynamics","display_name":"Computational fluid dynamics","score":0.4404100477695465},{"id":"https://openalex.org/keywords/air-trapping","display_name":"Air trapping","score":0.43447935581207275},{"id":"https://openalex.org/keywords/pulmonary-function-testing","display_name":"Pulmonary function testing","score":0.4187489151954651},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3975772261619568},{"id":"https://openalex.org/keywords/intensive-care-medicine","display_name":"Intensive care medicine","score":0.3424023389816284},{"id":"https://openalex.org/keywords/aerosol","display_name":"Aerosol","score":0.21536913514137268},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.17000681161880493},{"id":"https://openalex.org/keywords/mechanical-engineering","display_name":"Mechanical engineering","score":0.14216360449790955},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.13487893342971802},{"id":"https://openalex.org/keywords/aerospace-engineering","display_name":"Aerospace engineering","score":0.13252505660057068},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.1313389241695404},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.09067389369010925}],"concepts":[{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.6508665680885315},{"id":"https://openalex.org/C2961886","wikidata":"https://www.wikidata.org/wiki/Q7140496","display_name":"Particle deposition","level":3,"score":0.5565035939216614},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.548849880695343},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.5259459614753723},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5174737572669983},{"id":"https://openalex.org/C116067010","wikidata":"https://www.wikidata.org/wiki/Q4698686","display_name":"Airflow","level":2,"score":0.4912559390068054},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.48229268193244934},{"id":"https://openalex.org/C1633027","wikidata":"https://www.wikidata.org/wiki/Q815820","display_name":"Computational fluid dynamics","level":2,"score":0.4404100477695465},{"id":"https://openalex.org/C2777223847","wikidata":"https://www.wikidata.org/wiki/Q407922","display_name":"Air trapping","level":3,"score":0.43447935581207275},{"id":"https://openalex.org/C75603125","wikidata":"https://www.wikidata.org/wiki/Q1877462","display_name":"Pulmonary function testing","level":2,"score":0.4187489151954651},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3975772261619568},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3424023389816284},{"id":"https://openalex.org/C2779345167","wikidata":"https://www.wikidata.org/wiki/Q104541","display_name":"Aerosol","level":2,"score":0.21536913514137268},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.17000681161880493},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.14216360449790955},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13487893342971802},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.13252505660057068},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1313389241695404},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09067389369010925},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000280","descriptor_name":"Administration, Inhalation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000280","descriptor_name":"Administration, Inhalation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000280","descriptor_name":"Administration, Inhalation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008173","descriptor_name":"Lung Diseases, Obstructive","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008173","descriptor_name":"Lung Diseases, Obstructive","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008173","descriptor_name":"Lung Diseases, Obstructive","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057446","descriptor_name":"Hydrodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057446","descriptor_name":"Hydrodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057446","descriptor_name":"Hydrodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1186/s12911-017-0561-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-017-0561-y","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-017-0561-y","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},{"id":"pmid:29297393","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29297393","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical informatics and decision making","raw_type":null},{"id":"pmh:oai:doaj.org/article:4551cf70a7784698a4802b1cc669f063","is_oa":true,"landing_page_url":"https://doaj.org/article/4551cf70a7784698a4802b1cc669f063","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Informatics and Decision Making, Vol 17, Iss S3, Pp 25-44 (2017)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4668079","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5751792","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:spiral.imperial.ac.uk:10044/1/56205","is_oa":true,"landing_page_url":"http://hdl.handle.net/10044/1/56205","pdf_url":null,"source":{"id":"https://openalex.org/S4306401396","display_name":"Spiral (Imperial College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I47508984","host_organization_name":"Imperial College London","host_organization_lineage":["https://openalex.org/I47508984"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:143611","is_oa":false,"landing_page_url":"https://biblio.vub.ac.be/vubir/substance-deposition-assessment-in-obstructed-pulmonary-system-through-numerical-characterization-of-airflow-and-inhaled-particles-attributes(535fb0bc-6e48-4795-8ec8-4e8c5b46ba65).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:250967","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12911-017-0561-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-017-0561-y","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-017-0561-y","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5099999904632568,"id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G4365905886","display_name":null,"funder_award_id":"-2014-2015","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G522893879","display_name":null,"funder_award_id":"H2020-PHC-2014","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"}],"funders":[{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2781351714.pdf","grobid_xml":"https://content.openalex.org/works/W2781351714.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1145070682","https://openalex.org/W1569730344","https://openalex.org/W1907806303","https://openalex.org/W1982770119","https://openalex.org/W1988200254","https://openalex.org/W1989540182","https://openalex.org/W1999394052","https://openalex.org/W2006567640","https://openalex.org/W2023159816","https://openalex.org/W2027046977","https://openalex.org/W2029629524","https://openalex.org/W2032079286","https://openalex.org/W2059824688","https://openalex.org/W2062650460","https://openalex.org/W2073266737","https://openalex.org/W2073459066","https://openalex.org/W2086170438","https://openalex.org/W2086189390","https://openalex.org/W2097455141","https://openalex.org/W2099244020","https://openalex.org/W2105230277","https://openalex.org/W2115229157","https://openalex.org/W2118249065","https://openalex.org/W2119535220","https://openalex.org/W2125220690","https://openalex.org/W2140896035","https://openalex.org/W2143516773","https://openalex.org/W2148952796","https://openalex.org/W2153628012","https://openalex.org/W2169229115","https://openalex.org/W2172012864","https://openalex.org/W2272004637","https://openalex.org/W2335158011","https://openalex.org/W2422411849","https://openalex.org/W2469514806","https://openalex.org/W2497697999","https://openalex.org/W2563113634","https://openalex.org/W2576925548","https://openalex.org/W3042164605"],"related_works":["https://openalex.org/W2792350703","https://openalex.org/W2595428929","https://openalex.org/W3031912055","https://openalex.org/W1991863356","https://openalex.org/W2082544557","https://openalex.org/W2052380406","https://openalex.org/W2418927883","https://openalex.org/W2065376197","https://openalex.org/W1995228457","https://openalex.org/W3027773202"],"abstract_inverted_index":{"Chronic":[0],"obstructive":[1,14],"pulmonary":[2,155,195,329],"disease":[3,156],"(COPD)":[4],"and":[5,159,180,206,225,262,275,298,302,317,393,480,529,544,574,577,597,609],"asthma":[6],"are":[7,95,157,253,285,354,404,413,463,483],"considered":[8],"as":[9,178],"the":[10,27,34,39,45,48,59,62,69,91,105,111,127,135,142,149,164,171,200,204,207,214,229,244,267,283,293,300,311,314,328,334,344,348,357,364,387,397,407,416,423,438,470,487,493,501,505,512,522,568,581,618],"two":[11,248],"most":[12,352,411],"widespread":[13],"lung":[15,99,235,246,269,350,359,409,451,553,616],"diseases,":[16],"whereas":[17,473],"they":[18,103],"affect":[19,119],"more":[20],"than":[21],"500":[22],"million":[23],"people":[24],"worldwide.":[25],"Unfortunately,":[26],"requirement":[28],"for":[29,44,61,98,134,530,628],"detailed":[30,72,307],"geometric":[31,201],"models":[32,147,256,263],"of":[33,47,65,68,90,107,113,138,148,163,170,173,194,203,211,250,282,313,321,327,337,347,361,384,420,440,450,477,547,557,571,583,631],"lungs":[35,205,261,284,382],"in":[36,58,197,208,259,266,319,380,486,500,552,586,591],"combination":[37],"with":[38,168,234,257,264,455,475,560,603],"increased":[40,497],"computational":[41,78],"resources":[42],"needed":[43],"simulation":[46],"breathing":[49],"did":[50],"not":[51],"allow":[52],"great":[53],"progress":[54],"to":[55,122,154,199,227,460,465,519,593,624],"be":[56,341,466,565],"made":[57],"past":[60],"better":[63,136],"understanding":[64,106,210],"inflammatory":[66],"diseases":[67,237,559],"airways":[70,112,150,240,503],"through":[71,292],"modelling":[73],"approaches.":[74],"In":[75,124,331,400],"this":[76,125,332],"context,":[77],"fluid":[79,85],"dynamics":[80],"(CFD)":[81],"simulations":[82,540,576],"accompanied":[83],"by":[84,287,538,567,579],"particle":[86,108,139,175,506,595,598,607],"tracing":[87],"(FPT)":[88],"analysis":[89,309,495],"inhaled":[92,174,431,561,584],"ambient":[93],"particles":[94,315,353,412,454,474,513,585],"deemed":[96],"critical":[97],"function":[100],"assessment.":[101],"Also":[102],"enable":[104],"depositions":[109],"on":[110,356,406,415,469,526,614],"patients,":[114],"since":[115],"these":[116,289],"accumulations":[117],"may":[118],"or":[120],"lead":[121],"inflammations.":[123],"direction,":[126],"current":[128,494,619],"study":[129,620],"conducts":[130],"an":[131,191,542],"initial":[132,622],"investigation":[133],"comprehension":[137],"deposition":[140,276,323,335,582,613],"within":[141,213],"lungs.":[143],"More":[144],"specifically,":[145],"accurate":[146,543,572],"obstructions":[151,258,377,394],"that":[152,238,372,430],"relate":[153],"developed":[158,405],"a":[160,187,306,370,491,587,601,625],"thorough":[161],"assessment":[162],"airflow":[165,274],"behavior":[166],"together":[167],"identification":[169],"effects":[172,312],"properties,":[176],"such":[177],"size":[179,316,608],"density,":[181],"is":[182,223,367,373,390,426,433,444,508,524],"conducted.":[183],"Our":[184],"approach":[185],"presents":[186],"first":[188],"step":[189],"towards":[190],"effective":[192],"personalization":[193],"treatment":[196,449,556],"regards":[198,592],"characteristics":[202,605],"depth":[209],"airflows":[212],"airways.":[215,489],"A":[216],"geometry":[217],"processing":[218],"technique":[219],"involving":[220],"contraction":[221],"algorithms":[222],"established":[224],"used":[226],"employ":[228],"different":[230,594],"respiratory":[231,558],"arrangements":[232],"associated":[233],"related":[236],"exhibit":[239],"obstructions.":[241],"Apart":[242],"from":[243,437,457,516],"normal":[245],"case,":[247],"categories":[249],"obstructed":[251],"cases":[252,532],"examined,":[254],"i.e.":[255],"both":[260,381],"narrowings":[265,403],"right":[268,358,408],"only.":[270],"Precise":[271],"assumptions":[272],"regarding":[273],"fraction":[277],"(DF)":[278],"over":[279],"various":[280,338],"sections":[281],"drawn":[286],"simulating":[288],"distinct":[290],"incidents":[291],"finite":[294],"volume":[295],"method":[296],"(FVM)":[297],"particularly":[299],"CFD":[301,573],"FPT":[303,575],"algorithms.":[304],"Moreover,":[305],"parametric":[308],"clarifies":[310],"density":[318,514],"terms":[320],"regional":[322,588],"upon":[324],"several":[325],"parts":[326],"system.":[330],"manner,":[333],"pattern":[336],"substances":[339,563],"can":[340,564],"assessed.":[342],"For":[343],"specific":[345,604],"case":[346],"unobstructed":[349],"model":[351],"detected":[355],"(48.56%":[360],"total,":[362,385,421],"when":[363,376,386,402,422,446,504,511],"air":[365,388,424],"flowrate":[366,389,425],"12.6":[368],"L/min),":[369],"fact":[371],"also":[374],"true":[375],"arise":[378],"symmetrically":[379],"(51.45%":[383],"6.06":[391],"L/min":[392],"occur":[395],"after":[396],"second":[398],"generation).":[399],"contrast,":[401],"only,":[410],"pushed":[414],"left":[417],"section":[418],"(68.22%":[419],"11.2":[427],"L/min)":[428],"indicating":[429],"medication":[432],"generally":[434],"deposited":[435,468],"away":[436],"areas":[439],"inflammation.":[441],"This":[442],"observation":[443],"useful":[445],"designing":[447],"medical":[448,562],"diseases.":[452],"Furthermore,":[453],"diameters":[456,476],"1":[458],"\u03bcm":[459,462,479,482],"10":[461],"shown":[464],"mainly":[467],"lower":[471],"airways,":[472],"20":[478],"30":[481],"mostly":[484],"accumulated":[485],"upper":[488,502],"As":[490],"result,":[492],"indicates":[496],"DF":[498,523],"levels":[499],"diameter":[507],"enlarged.":[509],"Additionally,":[510],"increases":[515],"1000":[517],"Kg/m3":[518],"2000":[520],"Kg/m3,":[521],"enhanced":[525],"every":[527],"generation":[528],"all":[531,548],"investigated":[533],"herein.":[534],"The":[535,555],"results":[536],"obtained":[537],"our":[539],"provide":[541],"quantitative":[545],"estimation":[546],"important":[549],"parameters":[550],"involved":[551],"modeling.":[554],"advanced":[566],"clinical":[569],"use":[570],"specifically":[578],"evaluating":[580],"oriented":[589],"perspective":[590],"sizes":[596],"densities.":[599],"Since":[600],"drug":[602],"(i.e.":[606],"density)":[610],"exhibits":[611],"maximum":[612],"particular":[615],"areas,":[617],"provides":[621],"indications":[623],"qualified":[626],"physician":[627],"proper":[629],"selection":[630],"medication.":[632]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-05-16T08:24:45.110214","created_date":"2025-10-10T00:00:00"}