{"id":"https://openalex.org/W2618235946","doi":"https://doi.org/10.1186/s12911-017-0475-8","title":"Clinical decisions surrounding genomic and proteomic testing among United States veterans treated for lung cancer within the Veterans Health Administration","display_name":"Clinical decisions surrounding genomic and proteomic testing among United States veterans treated for lung cancer within the Veterans Health Administration","publication_year":2017,"publication_date":"2017-05-30","ids":{"openalex":"https://openalex.org/W2618235946","doi":"https://doi.org/10.1186/s12911-017-0475-8","mag":"2618235946","pmid":"https://pubmed.ncbi.nlm.nih.gov/28558785"},"language":"en","primary_location":{"id":"doi:10.1186/s12911-017-0475-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-017-0475-8","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-017-0475-8","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-017-0475-8","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030877878","display_name":"Olga Efimova","orcid":"https://orcid.org/0000-0003-1874-8458"},"institutions":[{"id":"https://openalex.org/I4210089864","display_name":"VA Salt Lake City Healthcare System","ror":"https://ror.org/007fyq698","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210089864","https://openalex.org/I4210113540"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olga Efimova","raw_affiliation_strings":["Department of Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT, 84148, USA","Department of Veterans Affairs Salt Lake City Health Care System, Salt Lake City, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT, 84148, USA","institution_ids":["https://openalex.org/I4210089864"]},{"raw_affiliation_string":"Department of Veterans Affairs Salt Lake City Health Care System, Salt Lake City, USA","institution_ids":["https://openalex.org/I4210089864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075594049","display_name":"Brygida Berse","orcid":"https://orcid.org/0000-0002-0735-2792"},"institutions":[{"id":"https://openalex.org/I4210090056","display_name":"Bedford VA Research Corporation","ror":"https://ror.org/00caks861","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210090056"]},{"id":"https://openalex.org/I2800300635","display_name":"Edith Nourse Rogers Memorial Veterans Hospital","ror":"https://ror.org/015nymp25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2800300635","https://openalex.org/I4210095851"]},{"id":"https://openalex.org/I180297670","display_name":"RTI International","ror":"https://ror.org/052tfza37","country_code":"US","type":"funder","lineage":["https://openalex.org/I180297670"]},{"id":"https://openalex.org/I4210095851","display_name":"VA New England Healthcare System","ror":"https://ror.org/00s61s029","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210095851"]},{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brygida Berse","raw_affiliation_strings":["Boston University School of Medicine, 715 Albany Street, Boston, MA, 02118, USA","RTI International, 307 Waverley Oaks Rd, Waltham, MA, 02452, USA","Veterans Healthcare Administration Bedford, 200 Springs Rd, Bedford, MA, 01730, USA","Boston University School of Medicine, Boston, USA","RTI International, Waltham, USA","Veterans Healthcare Administration Bedford, Bedford, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University School of Medicine, 715 Albany Street, Boston, MA, 02118, USA","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"RTI International, 307 Waverley Oaks Rd, Waltham, MA, 02452, USA","institution_ids":["https://openalex.org/I180297670"]},{"raw_affiliation_string":"Veterans Healthcare Administration Bedford, 200 Springs Rd, Bedford, MA, 01730, USA","institution_ids":["https://openalex.org/I4210095851","https://openalex.org/I4210090056"]},{"raw_affiliation_string":"Boston University School of Medicine, Boston, USA","institution_ids":[]},{"raw_affiliation_string":"RTI International, Waltham, USA","institution_ids":["https://openalex.org/I180297670"]},{"raw_affiliation_string":"Veterans Healthcare Administration Bedford, Bedford, USA","institution_ids":["https://openalex.org/I2800300635"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028414008","display_name":"Daniel W. Denhalter","orcid":"https://orcid.org/0000-0002-0883-6756"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I4210089864","display_name":"VA Salt Lake City Healthcare System","ror":"https://ror.org/007fyq698","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210089864","https://openalex.org/I4210113540"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel W. Denhalter","raw_affiliation_strings":["Department of Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT, 84148, USA","University of Utah, 30 2000 E, Salt Lake City, UT, 84112, USA","Department of Veterans Affairs Salt Lake City Health Care System, Salt Lake City, USA","University of Utah, Salt Lake City, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT, 84148, USA","institution_ids":["https://openalex.org/I4210089864"]},{"raw_affiliation_string":"University of Utah, 30 2000 E, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Department of Veterans Affairs Salt Lake City Health Care System, Salt Lake City, USA","institution_ids":["https://openalex.org/I4210089864"]},{"raw_affiliation_string":"University of Utah, Salt Lake City, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037435182","display_name":"Scott L. DuVall","orcid":"https://orcid.org/0000-0002-4898-3865"},"institutions":[{"id":"https://openalex.org/I4210089864","display_name":"VA Salt Lake City Healthcare System","ror":"https://ror.org/007fyq698","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210089864","https://openalex.org/I4210113540"]},{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott L. DuVall","raw_affiliation_strings":["Department of Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT, 84148, USA","University of Utah, 30 2000 E, Salt Lake City, UT, 84112, USA","University of Utah, Salt Lake City, USA","Department of Veterans Affairs Salt Lake City Health Care System, Salt Lake City, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT, 84148, USA","institution_ids":["https://openalex.org/I4210089864"]},{"raw_affiliation_string":"University of Utah, 30 2000 E, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"University of Utah, Salt Lake City, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Department of Veterans Affairs Salt Lake City Health Care System, Salt Lake City, USA","institution_ids":["https://openalex.org/I4210089864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077005871","display_name":"Kelly K. Filipski","orcid":"https://orcid.org/0000-0002-8523-9162"},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kelly K. Filipski","raw_affiliation_strings":["National Cancer Institute, NIH, 9609 Medical Center Dr, Rockville, MD, 20850, USA","National Cancer Institute, NIH, Rockville, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Cancer Institute, NIH, 9609 Medical Center Dr, Rockville, MD, 20850, USA","institution_ids":["https://openalex.org/I4210140884"]},{"raw_affiliation_string":"National Cancer Institute, NIH, Rockville, USA","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048905024","display_name":"Michael Icardi","orcid":"https://orcid.org/0000-0002-1788-6595"},"institutions":[{"id":"https://openalex.org/I4210135841","display_name":"Iowa City VA Medical Center","ror":"https://ror.org/03r9k1585","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210132647","https://openalex.org/I4210135841","https://openalex.org/I4210159720"]},{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Icardi","raw_affiliation_strings":["Iowa City VA Medical Center, 601 Highway 6 West, Iowa City, IA, 52246-2208, USA","University of Iowa Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA, 52242, USA","Iowa City VA Medical Center, Iowa City, USA","University of Iowa Carver College of Medicine, Iowa City, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Iowa City VA Medical Center, 601 Highway 6 West, Iowa City, IA, 52246-2208, USA","institution_ids":["https://openalex.org/I4210135841"]},{"raw_affiliation_string":"University of Iowa Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA, 52242, USA","institution_ids":["https://openalex.org/I126307644"]},{"raw_affiliation_string":"Iowa City VA Medical Center, Iowa City, USA","institution_ids":["https://openalex.org/I4210135841"]},{"raw_affiliation_string":"University of Iowa Carver College of Medicine, Iowa City, USA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040851143","display_name":"Michael J. Kelley","orcid":"https://orcid.org/0000-0001-9523-6080"},"institutions":[{"id":"https://openalex.org/I4210139568","display_name":"Durham VA Medical Center","ror":"https://ror.org/034adnw64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210119589","https://openalex.org/I4210139568","https://openalex.org/I4210159720"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J. Kelley","raw_affiliation_strings":["Duke University School of Medicine, 2301 Erwin Rd, Durham, NC, 27710, USA","Durham VA Medical Center, 508 Fulton St, Durham, NC, 27705, USA","Durham VA Medical Center, Durham, USA","Duke University School of Medicine, Durham, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University School of Medicine, 2301 Erwin Rd, Durham, NC, 27710, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Durham VA Medical Center, 508 Fulton St, Durham, NC, 27705, USA","institution_ids":["https://openalex.org/I4210139568"]},{"raw_affiliation_string":"Durham VA Medical Center, Durham, USA","institution_ids":["https://openalex.org/I4210139568"]},{"raw_affiliation_string":"Duke University School of Medicine, Durham, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048214696","display_name":"Julie A. Lynch","orcid":"https://orcid.org/0000-0003-0108-2127"},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I180297670","display_name":"RTI International","ror":"https://ror.org/052tfza37","country_code":"US","type":"funder","lineage":["https://openalex.org/I180297670"]},{"id":"https://openalex.org/I4210089864","display_name":"VA Salt Lake City Healthcare System","ror":"https://ror.org/007fyq698","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210089864","https://openalex.org/I4210113540"]},{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I33434090","display_name":"University of Massachusetts Boston","ror":"https://ror.org/04ydmy275","country_code":"US","type":"education","lineage":["https://openalex.org/I33434090"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Julie A. Lynch","raw_affiliation_strings":["Department of Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT, 84148, USA. Julie.Lynch@va.gov","RTI International, 307 Waverley Oaks Rd, Waltham, MA, 02452, USA. Julie.Lynch@va.gov","University of Massachusetts College of Nursing & Health Sciences, 100 Morrissey Blvd, Boston, MA, 02125, USA. Julie.Lynch@va.gov","University of Utah, 30 2000 E, Salt Lake City, UT, 84112, USA. Julie.Lynch@va.gov","University of Utah, Salt Lake City, USA","University of Massachusetts College of Nursing & Health Sciences, Boston, USA","RTI International, Waltham, USA","Department of Veterans Affairs Salt Lake City Health Care System, Salt Lake City, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT, 84148, USA. Julie.Lynch@va.gov","institution_ids":[]},{"raw_affiliation_string":"RTI International, 307 Waverley Oaks Rd, Waltham, MA, 02452, USA. Julie.Lynch@va.gov","institution_ids":[]},{"raw_affiliation_string":"University of Massachusetts College of Nursing & Health Sciences, 100 Morrissey Blvd, Boston, MA, 02125, USA. Julie.Lynch@va.gov","institution_ids":[]},{"raw_affiliation_string":"University of Utah, 30 2000 E, Salt Lake City, UT, 84112, USA. Julie.Lynch@va.gov","institution_ids":[]},{"raw_affiliation_string":"University of Utah, Salt Lake City, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"University of Massachusetts College of Nursing & Health Sciences, Boston, USA","institution_ids":["https://openalex.org/I33434090","https://openalex.org/I111088046"]},{"raw_affiliation_string":"RTI International, Waltham, USA","institution_ids":["https://openalex.org/I180297670"]},{"raw_affiliation_string":"Department of Veterans Affairs Salt Lake City Health Care System, Salt Lake City, USA","institution_ids":["https://openalex.org/I4210089864"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5048214696"],"corresponding_institution_ids":["https://openalex.org/I111088046","https://openalex.org/I180297670","https://openalex.org/I223532165","https://openalex.org/I33434090","https://openalex.org/I4210089864"],"apc_list":{"value":1570,"currency":"GBP","value_usd":1925},"apc_paid":{"value":1570,"currency":"GBP","value_usd":1925},"fwci":0.4102,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.66548928,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"17","issue":"1","first_page":"71","last_page":"71"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.9577999711036682,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.9577999711036682,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.009600000455975533,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erlotinib","display_name":"Erlotinib","score":0.9142396450042725},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.8418362140655518},{"id":"https://openalex.org/keywords/veterans-affairs","display_name":"Veterans Affairs","score":0.6850715279579163},{"id":"https://openalex.org/keywords/lung-cancer","display_name":"Lung cancer","score":0.5382293462753296},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.500126838684082},{"id":"https://openalex.org/keywords/epidermal-growth-factor-receptor","display_name":"Epidermal growth factor receptor","score":0.4787989556789398},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.4771525263786316},{"id":"https://openalex.org/keywords/pharmacy","display_name":"Pharmacy","score":0.4613964259624481},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"Personalized medicine","score":0.4417741298675537},{"id":"https://openalex.org/keywords/health-care","display_name":"Health care","score":0.4328173100948334},{"id":"https://openalex.org/keywords/medline","display_name":"MEDLINE","score":0.4157985746860504},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.41481804847717285},{"id":"https://openalex.org/keywords/intensive-care-medicine","display_name":"Intensive care medicine","score":0.3818199634552002},{"id":"https://openalex.org/keywords/family-medicine","display_name":"Family medicine","score":0.3084501624107361},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.24990692734718323}],"concepts":[{"id":"https://openalex.org/C2778087573","wikidata":"https://www.wikidata.org/wiki/Q418369","display_name":"Erlotinib","level":4,"score":0.9142396450042725},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8418362140655518},{"id":"https://openalex.org/C2775969662","wikidata":"https://www.wikidata.org/wiki/Q7923600","display_name":"Veterans Affairs","level":2,"score":0.6850715279579163},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.5382293462753296},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.500126838684082},{"id":"https://openalex.org/C2779438470","wikidata":"https://www.wikidata.org/wiki/Q424401","display_name":"Epidermal growth factor receptor","level":3,"score":0.4787989556789398},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4771525263786316},{"id":"https://openalex.org/C104863432","wikidata":"https://www.wikidata.org/wiki/Q614304","display_name":"Pharmacy","level":2,"score":0.4613964259624481},{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.4417741298675537},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.4328173100948334},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.4157985746860504},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.41481804847717285},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3818199634552002},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.3084501624107361},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.24990692734718323},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003657","descriptor_name":"Decision Making","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003657","descriptor_name":"Decision Making","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003657","descriptor_name":"Decision Making","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008485","descriptor_name":"Medical Audit","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008485","descriptor_name":"Medical Audit","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008485","descriptor_name":"Medical Audit","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014493","descriptor_name":"United States Department of Veterans Affairs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014493","descriptor_name":"United States Department of Veterans Affairs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014493","descriptor_name":"United States Department of Veterans Affairs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066246","descriptor_name":"ErbB Receptors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D066246","descriptor_name":"ErbB Receptors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D066246","descriptor_name":"ErbB Receptors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12911-017-0475-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-017-0475-8","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-017-0475-8","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},{"id":"pmid:28558785","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28558785","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical informatics and decision making","raw_type":null},{"id":"pmh:oai:doaj.org/article:3d478c1b7eaf418391bcb859a5898ca9","is_oa":true,"landing_page_url":"https://doaj.org/article/3d478c1b7eaf418391bcb859a5898ca9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Informatics and Decision Making, Vol 17, Iss 1, Pp 1-8 (2017)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4306267","is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC5450357","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5450357","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5450357","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Inform Decis Mak","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12911-017-0475-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-017-0475-8","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-017-0475-8","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8100000023841858,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1860580546","display_name":null,"funder_award_id":"Interagency Agreement 14001-0000-01001","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2618235946.pdf","grobid_xml":"https://content.openalex.org/works/W2618235946.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W168635649","https://openalex.org/W1480161907","https://openalex.org/W1976083517","https://openalex.org/W1979282672","https://openalex.org/W1999130958","https://openalex.org/W2140832617","https://openalex.org/W2564462591","https://openalex.org/W2588675203","https://openalex.org/W2761667483","https://openalex.org/W2806575069","https://openalex.org/W4285719527","https://openalex.org/W6650358810"],"related_works":["https://openalex.org/W1994763147","https://openalex.org/W2120992361","https://openalex.org/W2023597833","https://openalex.org/W2076668512","https://openalex.org/W2541392164","https://openalex.org/W2360123363","https://openalex.org/W2168841302","https://openalex.org/W2896649837","https://openalex.org/W2035762060","https://openalex.org/W2103997800"],"abstract_inverted_index":{"BACKGROUND:":[0],"Current":[1],"clinical":[2,55,163,179,211,240],"guidelines":[3,87],"recommend":[4],"epidermal":[5],"growth":[6],"factor":[7],"receptor":[8],"(EGFR)":[9],"mutational":[10],"testing":[11,36,71,133,167,189,247],"in":[12,63,214,256,265],"patients":[13,40,73,140,230],"with":[14,41,74,113,141,178,261],"metastatic":[15],"non-small":[16],"cell":[17],"lung":[18],"cancer":[19],"(NSCLC)":[20],"to":[21,86,109],"predict":[22],"the":[23,26,77,89,130,138,208,229,243,252],"benefit":[24],"of":[25,79,91,99,132,188,192,224,228,245,259],"tyrosine":[27],"kinase":[28],"inhibitor":[29],"erlotinib":[30,48,169,249],"as":[31],"first-line":[32],"treatment.":[33,135,170],"Proteomic":[34,102],"(VeriStrat)":[35],"is":[37,49],"recommended":[38,253],"for":[39,183],"EGFR":[42,68,104,158,206,234],"negative":[43],"or":[44,174,190,220],"unknown":[45],"status":[46],"when":[47],"being":[50],"considered.":[51],"Departure":[52],"from":[53,107,203,251],"this":[54,215],"algorithm":[56],"can":[57],"increase":[58],"costs":[59,258],"and":[60,69,88,97,103,118,134,151,168,196,248],"may":[61],"result":[62],"worse":[64],"outcomes.":[65,267],"We":[66,83,160],"examined":[67],"proteomic":[70,145,246],"among":[72],"NSCLC":[75,142],"within":[76],"Department":[78],"Veterans":[80],"Affairs":[81],"(VA).":[82],"explored":[84],"adherence":[85],"impact":[90],"test":[92,105],"results":[93,106],"on":[94,129,233],"treatment":[95,193],"decisions":[96,164,172,186,199],"cost":[98],"care.":[100],"METHODS:":[101],"2013":[108],"2015":[110],"were":[111,123,126,149,176],"merged":[112],"VA":[114],"electronic":[115],"health":[116,266],"records":[117,223],"pharmacy":[119],"data.":[120],"Chart":[121],"reviews":[122],"conducted.":[124],"Cases":[125],"categorized":[127],"based":[128],"appropriateness":[131],"RESULTS:":[136],"Of":[137],"69":[139],"who":[143],"underwent":[144],"testing,":[146,207],"33":[147],"(48%)":[148],"EGFR-negative":[150],"36":[152],"(52%)":[153],"did":[154],"not":[155],"have":[156],"documented":[157,263],"status.":[159,235],"analyzed":[161,213],"138":[162],"surrounding":[165],"EGFR/proteomic":[166],"Most":[171],"(105,":[173],"76%)":[175],"concordant":[177],"practice":[180],"guidelines.":[181,204],"However,":[182],"24":[184],"(17%)":[185],"documentation":[187],"justification":[191],"was":[194,217],"inadequate,":[195],"9":[197],"(7%)":[198],"represented":[200],"clear":[201],"departures":[202],"CONCLUSION:":[205],"least":[209],"expensive":[210],"intervention":[212],"study,":[216],"significantly":[218],"underutilized":[219],"undocumented.":[221],"The":[222],"more":[225],"than":[226],"half":[227],"lacked":[231],"information":[232],"Our":[236],"analysis":[237],"illustrated":[238],"several":[239],"scenarios":[241],"where":[242],"timing":[244],"diverged":[250],"algorithm,":[254],"resulting":[255],"excessive":[257],"care":[260],"no":[262],"improvements":[264]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}