{"id":"https://openalex.org/W7172517684","doi":"https://doi.org/10.1186/s12880-026-02622-7","title":"Online adaptive radiotherapy in pelvic and thoracic cancers - comparing toxicities, clinical outcomes and technical parameters between conventional image-guided radiotherapy and online adaptive radiotherapy \u2013 the study protocol for the prospective, registry-based cohort study (PRoART)","display_name":"Online adaptive radiotherapy in pelvic and thoracic cancers - comparing toxicities, clinical outcomes and technical parameters between conventional image-guided radiotherapy and online adaptive radiotherapy \u2013 the study protocol for the prospective, registry-based cohort study (PRoART)","publication_year":2026,"publication_date":"2026-08-05","ids":{"openalex":"https://openalex.org/W7172517684","doi":"https://doi.org/10.1186/s12880-026-02622-7","pmid":"https://pubmed.ncbi.nlm.nih.gov/42557552"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-026-02622-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02622-7","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12880-026-02622-7.pdf","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s12880-026-02622-7.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037335105","display_name":"Laura Anna Fischer","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Laura Anna Fischer","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany. laura-anna.fischer@med.uni-goettingen.de"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany. laura-anna.fischer@med.uni-goettingen.de","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075824894","display_name":"Jann Fischer","orcid":"https://orcid.org/0009-0002-8826-5662"},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jann Fischer","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099337489","display_name":"Niklas Christian Scheele","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Niklas Christian Scheele","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082612460","display_name":"Leif Hendrik Droege","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Leif Hendrik Droege","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5144440558","display_name":"Martin Leu","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martin Leu","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019789492","display_name":"Manuel Guhlich","orcid":"https://orcid.org/0000-0002-2599-6196"},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Manuel Guhlich","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072787929","display_name":"Jan Tobias Oelmann-Avendano","orcid":null},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jan Tobias Oelmann-Avendano","raw_affiliation_strings":["Department of Radiation Oncology, University Hospital Hamburg-Eppendorf (UKE), Martinistra\u00dfe 52, 20246, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University Hospital Hamburg-Eppendorf (UKE), Martinistra\u00dfe 52, 20246, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035906520","display_name":"A. Hille","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andrea Hille","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093539756","display_name":"Stephanie Bendrich","orcid":"https://orcid.org/0009-0001-6562-6616"},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stephanie Bendrich","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013736476","display_name":"Sandra Donath","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sandra Donath","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057899752","display_name":"Olga Knaus","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Olga Knaus","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028075428","display_name":"David Alexander Ziegler","orcid":"https://orcid.org/0000-0002-1469-8767"},"institutions":[{"id":"https://openalex.org/I4210143701","display_name":"Medizinische Universit\u00e4t Lausitz - Carl Thiem","ror":"https://ror.org/044fhy270","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210143701"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"David Alexander Ziegler","raw_affiliation_strings":["Department of Radiation Oncology, Medical University of Lusatia - Carl Thiem, Thiemstra\u00dfe 111, 03048, Cottbus, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Medical University of Lusatia - Carl Thiem, Thiemstra\u00dfe 111, 03048, Cottbus, Germany","institution_ids":["https://openalex.org/I4210143701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054847793","display_name":"Carla Marie Zwerenz","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Carla Marie Zwerenz","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015898665","display_name":"Mahalia Zoe Anczykowski","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Mahalia Zoe Anczykowski","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083754103","display_name":"Hanne Elisabeth Ammon","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hanne Elisabeth Ammon","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030104593","display_name":"Pia Franziska Luise Bergau","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Pia Franziska Luise Bergau","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099337486","display_name":"Charlotta Friederike Pagel","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Charlotta Friederike Pagel","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030268100","display_name":"Markus Schirmer","orcid":"https://orcid.org/0000-0003-1375-4496"},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Markus Anton Schirmer","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113259910","display_name":"Alina Renata Wenzel","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alina Renata Wenzel","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014331833","display_name":"Jasper Frohn","orcid":"https://orcid.org/0000-0003-3849-6032"},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jasper Frohn","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099337488","display_name":"Jona Bensberg","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jona Bensberg","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5144401489","display_name":"Arne Strau\u00df","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Arne Strau\u00df","raw_affiliation_strings":["Department of Urology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088613638","display_name":"Thomas Asendorf","orcid":"https://orcid.org/0000-0003-1317-2138"},"institutions":[{"id":"https://openalex.org/I2802849423","display_name":"University Medical Center","ror":"https://ror.org/036pt7h44","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802849423"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Asendorf","raw_affiliation_strings":["Department of Medical Statistics University Medical Center Goettingen (UMG), Humboldtallee 32, 37073, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Statistics University Medical Center Goettingen (UMG), Humboldtallee 32, 37073, Goettingen, Germany","institution_ids":["https://openalex.org/I2802849423"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044560746","display_name":"Daniela Schmitt","orcid":"https://orcid.org/0000-0002-9657-0715"},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Daniela Schmitt","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5144459676","display_name":"Stefan Rieken","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Rieken","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5144427415","display_name":"Rami Atejah El Shafie","orcid":null},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Rami Atejah El Shafie","raw_affiliation_strings":["Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Medical Center Goettingen (UMG), Robert-Koch-Stra\u00dfe 40, 37075, Goettingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5037335105"],"corresponding_institution_ids":["https://openalex.org/I74656192"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":{"value":3090,"currency":"USD","value_usd":3090},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.80227134,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9642000198364258,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9642000198364258,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiation-therapy","display_name":"Radiation therapy","score":0.7311999797821045},{"id":"https://openalex.org/keywords/image-guided-radiation-therapy","display_name":"Image-guided radiation therapy","score":0.6438000202178955},{"id":"https://openalex.org/keywords/common-terminology-criteria-for-adverse-events","display_name":"Common Terminology Criteria for Adverse Events","score":0.538100004196167},{"id":"https://openalex.org/keywords/protocol","display_name":"Protocol (science)","score":0.4916999936103821},{"id":"https://openalex.org/keywords/radiation-treatment-planning","display_name":"Radiation treatment planning","score":0.41690000891685486},{"id":"https://openalex.org/keywords/clinical-endpoint","display_name":"Clinical endpoint","score":0.3831000030040741},{"id":"https://openalex.org/keywords/prospective-cohort-study","display_name":"Prospective cohort study","score":0.350600004196167},{"id":"https://openalex.org/keywords/randomized-controlled-trial","display_name":"Randomized controlled trial","score":0.32350000739097595}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8773000240325928},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.7311999797821045},{"id":"https://openalex.org/C9267231","wikidata":"https://www.wikidata.org/wiki/Q15841445","display_name":"Image-guided radiation therapy","level":3,"score":0.6438000202178955},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5838000178337097},{"id":"https://openalex.org/C2777793932","wikidata":"https://www.wikidata.org/wiki/Q1116229","display_name":"Common Terminology Criteria for Adverse Events","level":3,"score":0.538100004196167},{"id":"https://openalex.org/C2780385302","wikidata":"https://www.wikidata.org/wiki/Q367158","display_name":"Protocol (science)","level":3,"score":0.4916999936103821},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.45660001039505005},{"id":"https://openalex.org/C201645570","wikidata":"https://www.wikidata.org/wiki/Q830637","display_name":"Radiation treatment planning","level":3,"score":0.41690000891685486},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.3831000030040741},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.350600004196167},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.32350000739097595},{"id":"https://openalex.org/C2780920918","wikidata":"https://www.wikidata.org/wiki/Q7280361","display_name":"Radiation oncologist","level":3,"score":0.3197999894618988},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2939000129699707},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.2930000126361847},{"id":"https://openalex.org/C2778357063","wikidata":"https://www.wikidata.org/wiki/Q713102","display_name":"Pelvis","level":2,"score":0.274399995803833},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.26809999346733093},{"id":"https://openalex.org/C75088862","wikidata":"https://www.wikidata.org/wiki/Q2291081","display_name":"Dosimetry","level":2,"score":0.26030001044273376},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.26010000705718994},{"id":"https://openalex.org/C161471255","wikidata":"https://www.wikidata.org/wiki/Q374703","display_name":"Multileaf collimator","level":4,"score":0.2578999996185303}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010386","descriptor_name":"Pelvic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D010386","descriptor_name":"Pelvic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D010386","descriptor_name":"Pelvic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D010386","descriptor_name":"Pelvic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D010386","descriptor_name":"Pelvic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D010386","descriptor_name":"Pelvic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D010386","descriptor_name":"Pelvic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D010386","descriptor_name":"Pelvic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D010386","descriptor_name":"Pelvic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D010386","descriptor_name":"Pelvic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013899","descriptor_name":"Thoracic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013899","descriptor_name":"Thoracic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013899","descriptor_name":"Thoracic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013899","descriptor_name":"Thoracic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013899","descriptor_name":"Thoracic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013899","descriptor_name":"Thoracic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D013899","descriptor_name":"Thoracic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D013899","descriptor_name":"Thoracic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D013899","descriptor_name":"Thoracic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D013899","descriptor_name":"Thoracic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061089","descriptor_name":"Radiotherapy, Image-Guided","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D061089","descriptor_name":"Radiotherapy, Image-Guided","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D061089","descriptor_name":"Radiotherapy, Image-Guided","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D061089","descriptor_name":"Radiotherapy, Image-Guided","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D061089","descriptor_name":"Radiotherapy, Image-Guided","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D061089","descriptor_name":"Radiotherapy, Image-Guided","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D061089","descriptor_name":"Radiotherapy, Image-Guided","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D061089","descriptor_name":"Radiotherapy, Image-Guided","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D061089","descriptor_name":"Radiotherapy, Image-Guided","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D061089","descriptor_name":"Radiotherapy, Image-Guided","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12880-026-02622-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02622-7","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12880-026-02622-7.pdf","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:42557552","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42557552","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:b2f00469ad6348b58455df696b48ead8","is_oa":false,"landing_page_url":"https://doaj.org/article/b2f00469ad6348b58455df696b48ead8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 26, Iss 1 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13445679","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13445679/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Imaging","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12880-026-02622-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02622-7","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12880-026-02622-7.pdf","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4467613399028778,"display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320318756","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7172517684.pdf","grobid_xml":"https://content.openalex.org/works/W7172517684.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W2008090769","https://openalex.org/W2035429331","https://openalex.org/W2072086191","https://openalex.org/W2119467645","https://openalex.org/W2137282952","https://openalex.org/W2140110477","https://openalex.org/W2161523978","https://openalex.org/W2275338432","https://openalex.org/W2364135209","https://openalex.org/W2528393079","https://openalex.org/W3011596192","https://openalex.org/W3197466924","https://openalex.org/W3217050965","https://openalex.org/W4210802496","https://openalex.org/W4220762416","https://openalex.org/W4283313052","https://openalex.org/W4404052481"],"related_works":[],"abstract_inverted_index":{"BACKGROUND:":[0],"Conventional":[1],"image-guided":[2,151],"radiotherapy":[3,100],"(IGRT)":[4],"typically":[5],"relies":[6],"on":[7,45,145,159],"a":[8,28,42,46,103,122,235,324,345,358],"computed":[9],"tomography":[10],"(CT)-based":[11],"treatment":[12,30,147,156],"planning":[13],"process":[14],"(planning":[15],"CT,":[16],"pCT)":[17],"performed":[18],"prior":[19],"to":[20,38,53,108,120,188,283,343,374],"the":[21,39,125,131,142,146,154,160,163,177,225,239,290,306,349,355,367],"start":[22],"of":[23,124,153,162,241,321,351,357],"treatment.":[24],"During":[25],"this":[26,376],"process,":[27],"patient-specific":[29],"plan":[31,158],"is":[32,35,102,128,173,197,232,341],"generated,":[33],"which":[34],"then":[36],"delivered":[37],"patient":[40,58,133,143],"with":[41,50,130,209,214,220],"linear":[43],"accelerator":[44],"daily":[47,61,118,150],"basis,":[48],"usually":[49],"image":[51],"guidance":[52],"compensate":[54],"for":[55,185,217,249,297,315],"variations":[56,64],"in":[57,65,74,90,176,192,238,326,335,348],"setup.":[59],"However,":[60],"interfractional":[62,182],"anatomical":[63,183,286],"target":[66,165,279,330],"position,":[67],"shape,":[68],"and":[69,94,105,194,268,285,299,328,363],"volume,":[70,280],"as":[71,73,234,272,274,278],"well":[72,273],"surrounding":[75],"organs":[76],"at":[77],"risk":[78],"(OARs),":[79],"can":[80],"only":[81],"be":[82,169,344],"addressed":[83],"indirectly":[84],"by":[85,137],"adding":[86],"safety":[87],"margins,":[88],"resulting":[89,334],"larger":[91],"irradiated":[92],"volumes":[93],"potentially":[95,333],"increased":[96],"toxicity.":[97,115],"Online":[98],"adaptive":[99],"(oART)":[101],"promising":[104],"innovative":[106],"technique":[107],"reduce":[109],"such":[110,277],"margins":[111],"and,":[112],"consequently,":[113],"treatment-related":[114],"It":[116,340],"uses":[117],"imaging":[119],"generate":[121],"\"plan":[123],"day\"":[126],"that":[127],"aligned":[129],"current":[132],"anatomy,":[134],"often":[135],"supported":[136],"artificial":[138],"intelligence":[139],"(AI),":[140],"while":[141],"remains":[144],"couch.":[148],"Through":[149],"re-optimization":[152],"radiation":[155,352],"(RT)":[157],"anatomy":[161],"day,":[164],"coverage":[166],"may":[167],"also":[168,304],"improved.":[170],"This":[171,201],"approach":[172],"particularly":[174],"attractive":[175],"pelvic":[178,210],"region,":[179],"where":[180],"high":[181],"variability,":[184],"example":[186],"due":[187],"peristalsis":[189],"or":[190,211,222],"changes":[191],"bladder":[193],"rectal":[195],"filling,":[196],"frequently":[198],"observed.":[199],"METHODS:":[200],"prospective":[202,368],"registry-based":[203,369],"cohort":[204,291,370],"study":[205,292,371],"will":[206],"include":[207],"patients":[208],"thoracic":[212],"tumors":[213],"an":[215],"indication":[216],"RT":[218,243],"treated":[219],"IGRT":[221,294,362],"oART":[223,296,308,322,364],"using":[224,255],"Varian":[226],"Ethos\u2122":[227],"system.":[228],"The":[229,319],"primary":[230,298],"endpoint":[231],"defined":[233],"10%":[236],"reduction":[237,325],"rate":[240],"acute":[242],"related":[244],"toxicity":[245],"(\u2265Common":[246],"Terminology":[247],"Criteria":[248],"Adverse":[250],"Events":[251],"(CTCAE)":[252],"II\u00b0,":[253],"v5.0)":[254],"oART.":[256],"Secondary":[257],"endpoints":[258],"encompass":[259],"clinical":[260,301],"outcomes":[261,270],"including":[262],"late":[263],"toxicities,":[264],"tumor":[265,337],"control":[266,313,338],"rates,":[267],"patient-reported":[269],"(PROs),":[271],"technical":[275,316],"factors":[276],"coverage,":[281,332],"dose":[282],"OARs":[284],"variability":[287],"score.":[288],"While":[289],"compares":[293],"versus":[295],"secondary":[300],"endpoints,":[302],"it":[303],"evaluates":[305],"real":[307],"scenario":[309],"against":[310],"two":[311],"hypothetical":[312],"scenarios":[314],"endpoints.":[317],"DISCUSSION:":[318],"introduction":[320],"promises":[323],"toxicities":[327],"improved":[329],"volume":[331],"enhanced":[336],"rates.":[339],"poised":[342],"pioneering":[346],"technology":[347],"field":[350],"oncology.":[353],"Given":[354],"absence":[356],"direct":[359],"comparison":[360],"between":[361],"thus":[365],"far,":[366],"PRoART":[372],"aims":[373],"address":[375],"gap.":[377],"TRIAL":[378],"REGISTRATION:":[379],"Clinical":[380],"trial":[381],"number":[382],"NCT06185062,":[383],"Clinicaltrials.gov.":[384],"Registered":[385],"12/14/2023.":[386],"Last":[387],"update":[388],"07/29/2026.":[389]},"counts_by_year":[],"updated_date":"2026-08-30T07:30:35.949966","created_date":"2026-08-06T00:00:00"}