{"id":"https://openalex.org/W7161572442","doi":"https://doi.org/10.1186/s12880-026-02367-3","title":"Preoperative synthetic magnetic resonance imaging-based biomarkers for predicting tumor budding of rectal cancer","display_name":"Preoperative synthetic magnetic resonance imaging-based biomarkers for predicting tumor budding of rectal cancer","publication_year":2026,"publication_date":"2026-05-18","ids":{"openalex":"https://openalex.org/W7161572442","doi":"https://doi.org/10.1186/s12880-026-02367-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/42151880"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-026-02367-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02367-3","pdf_url":null,"source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12880-026-02367-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101449412","display_name":"Kunpeng Zhou","orcid":"https://orcid.org/0000-0002-2555-6481"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210096354","display_name":"The Seventh Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/00rfd5b88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210096354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kun-Peng Zhou","raw_affiliation_strings":["Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210096354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126407767","display_name":"H Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210096354","display_name":"The Seventh Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/00rfd5b88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210096354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hua-Bin Huang","raw_affiliation_strings":["Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210096354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101917459","display_name":"Xu Cheng","orcid":"https://orcid.org/0000-0003-2392-2449"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210096354","display_name":"The Seventh Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/00rfd5b88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210096354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xian-Wen Cheng","raw_affiliation_strings":["Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210096354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5136395528","display_name":"Jie Bian","orcid":null},"institutions":[{"id":"https://openalex.org/I191996457","display_name":"Dalian Medical University","ror":"https://ror.org/04c8eg608","country_code":"CN","type":"education","lineage":["https://openalex.org/I191996457"]},{"id":"https://openalex.org/I4210100868","display_name":"Second Affiliated Hospital of Dalian Medical University","ror":"https://ror.org/012f2cn18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100868"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Bian","raw_affiliation_strings":["Department of Radiology, The Second Hospital of Dalian Medical University, Dalian, 116027, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Second Hospital of Dalian Medical University, Dalian, 116027, P.R. China","institution_ids":["https://openalex.org/I191996457","https://openalex.org/I4210100868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100420743","display_name":"Le Chen","orcid":"https://orcid.org/0000-0001-7588-5040"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210096354","display_name":"The Seventh Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/00rfd5b88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210096354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ling-Hao Chen","raw_affiliation_strings":["Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210096354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123172907","display_name":"Luo Z","orcid":null},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210096354","display_name":"The Seventh Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/00rfd5b88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210096354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhong-Xing Luo","raw_affiliation_strings":["Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210096354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109781916","display_name":"Weijian Lai","orcid":null},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210096354","display_name":"The Seventh Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/00rfd5b88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210096354"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wei-Jian Lai","raw_affiliation_strings":["Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China. laiweijian@sysush.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China. laiweijian@sysush.com","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210096354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013926363","display_name":"Di-Min Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210096354","display_name":"The Seventh Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/00rfd5b88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210096354"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Di-Min Liu","raw_affiliation_strings":["Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China. liudimin@sysush.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China. liudimin@sysush.com","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210096354"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111915941","display_name":"Qing-yu Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210096354","display_name":"The Seventh Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/00rfd5b88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210096354"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qing-Yu Liu","raw_affiliation_strings":["Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China. liuqingyu@sysush.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-Sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen, Guangdong, 518107, P.R. China. liuqingyu@sysush.com","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210096354"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5013926363","https://openalex.org/A5109781916","https://openalex.org/A5111915941"],"corresponding_institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210096354"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":{"value":3090,"currency":"USD","value_usd":3090},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.45060866,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9700000286102295,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9700000286102295,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.007899999618530273,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/akaike-information-criterion","display_name":"Akaike information criterion","score":0.7401000261306763},{"id":"https://openalex.org/keywords/brier-score","display_name":"Brier score","score":0.7242000102996826},{"id":"https://openalex.org/keywords/logistic-regression","display_name":"Logistic regression","score":0.6980999708175659},{"id":"https://openalex.org/keywords/receiver-operating-characteristic","display_name":"Receiver operating characteristic","score":0.633400022983551},{"id":"https://openalex.org/keywords/categorical-variable","display_name":"Categorical variable","score":0.5512999892234802},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"Colorectal cancer","score":0.5331000089645386},{"id":"https://openalex.org/keywords/metric","display_name":"Metric (unit)","score":0.4943999946117401},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.4936999976634979},{"id":"https://openalex.org/keywords/predictive-value","display_name":"Predictive value","score":0.4474000036716461}],"concepts":[{"id":"https://openalex.org/C126674687","wikidata":"https://www.wikidata.org/wiki/Q1662573","display_name":"Akaike information criterion","level":2,"score":0.7401000261306763},{"id":"https://openalex.org/C35405484","wikidata":"https://www.wikidata.org/wiki/Q4967066","display_name":"Brier score","level":2,"score":0.7242000102996826},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.6980999708175659},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6754000186920166},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.633400022983551},{"id":"https://openalex.org/C5274069","wikidata":"https://www.wikidata.org/wiki/Q2285707","display_name":"Categorical variable","level":2,"score":0.5512999892234802},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.5331000089645386},{"id":"https://openalex.org/C176217482","wikidata":"https://www.wikidata.org/wiki/Q860554","display_name":"Metric (unit)","level":2,"score":0.4943999946117401},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.4936999976634979},{"id":"https://openalex.org/C3019719930","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value","level":2,"score":0.4474000036716461},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.42160001397132874},{"id":"https://openalex.org/C83546350","wikidata":"https://www.wikidata.org/wiki/Q1139051","display_name":"Regression","level":2,"score":0.3749000132083893},{"id":"https://openalex.org/C2776291640","wikidata":"https://www.wikidata.org/wiki/Q2912517","display_name":"Value (mathematics)","level":2,"score":0.3691999912261963},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.35690000653266907},{"id":"https://openalex.org/C2779188454","wikidata":"https://www.wikidata.org/wiki/Q16948689","display_name":"Tumor budding","level":5,"score":0.3540000021457672},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.349700003862381},{"id":"https://openalex.org/C152877465","wikidata":"https://www.wikidata.org/wiki/Q208042","display_name":"Regression analysis","level":2,"score":0.3483000099658966},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.33489999175071716},{"id":"https://openalex.org/C2983394010","wikidata":"https://www.wikidata.org/wiki/Q19885330","display_name":"Continuous variable","level":2,"score":0.3264999985694885},{"id":"https://openalex.org/C198433322","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value of tests","level":2,"score":0.3222000002861023},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30959999561309814},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2930000126361847},{"id":"https://openalex.org/C3020225094","wikidata":"https://www.wikidata.org/wiki/Q80091","display_name":"Area under curve","level":3,"score":0.2915000021457672},{"id":"https://openalex.org/C2776474662","wikidata":"https://www.wikidata.org/wiki/Q1578147","display_name":"Magnetic resonance cholangiopancreatography","level":4,"score":0.2786000072956085},{"id":"https://openalex.org/C48921125","wikidata":"https://www.wikidata.org/wiki/Q10861030","display_name":"Linear regression","level":2,"score":0.27730000019073486},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.2766999900341034}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060787","descriptor_name":"Neoplasm Grading","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060787","descriptor_name":"Neoplasm Grading","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060787","descriptor_name":"Neoplasm Grading","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060787","descriptor_name":"Neoplasm Grading","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12880-026-02367-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02367-3","pdf_url":null,"source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:42151880","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42151880","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13360884","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13360884/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13360884/pdf/12880_2026_Article_2367.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Imaging","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:993ba50cf9a74f5b941206c6657234c2","is_oa":false,"landing_page_url":"https://doaj.org/article/993ba50cf9a74f5b941206c6657234c2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 26, Iss 1 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12880-026-02367-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02367-3","pdf_url":null,"source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5701996088027954,"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities"},{"score":0.40114596486091614,"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W74633811","https://openalex.org/W1788937818","https://openalex.org/W2006648625","https://openalex.org/W2046089103","https://openalex.org/W2123328938","https://openalex.org/W2174548352","https://openalex.org/W2175125464","https://openalex.org/W2438208391","https://openalex.org/W2518445393","https://openalex.org/W2620163964","https://openalex.org/W2900353253","https://openalex.org/W2921207121","https://openalex.org/W2979569959","https://openalex.org/W3020110584","https://openalex.org/W3034749039","https://openalex.org/W3037815346","https://openalex.org/W3083938091","https://openalex.org/W3105648835","https://openalex.org/W3111785202","https://openalex.org/W3128803645","https://openalex.org/W3129801988","https://openalex.org/W3137766245","https://openalex.org/W3194500022","https://openalex.org/W3195158111","https://openalex.org/W4213227070","https://openalex.org/W4223457911","https://openalex.org/W4283009410","https://openalex.org/W4283836472","https://openalex.org/W4309160812"],"related_works":[],"abstract_inverted_index":{"BACKGROUND:":[0],"Tumor":[1],"budding":[2],"(TB)":[3],"is":[4],"recognized":[5],"as":[6,105],"an":[7,210],"independent":[8,114,197,268],"prognostic":[9],"factor":[10],"in":[11,38,273],"rectal":[12],"cancer":[13],"(RC).":[14],"This":[15],"study":[16],"aimed":[17],"to":[18,29,112,123],"evaluate":[19],"the":[20,98,125,140,154,158,215,224,234],"ability":[21],"of":[22,43,74,116,128,199,212,265,270,308],"preoperative":[23],"synthetic":[24],"MRI":[25],"(SyMRI)":[26],"quantitative":[27],"parameters":[28],"predict":[30],"high-grade":[31,53,117,168,200,271],"TB":[32,54,59,166,169,272,309],"(\u2265":[33],"10":[34,61],"buds,":[35,62],"Bd":[36,63],"3)":[37],"RC.":[39,274],"METHODS:":[40],"A":[41,275],"total":[42],"105":[44],"patients":[45],"with":[46,52,57,164,293],"RC":[47],"were":[48,76,86,95,151,196],"enrolled,":[49],"including":[50],"42":[51],"and":[55,65,71,92,131,145,147,157,179,193,205,223,245,247,257,262,280,286,290,299],"63":[56],"non-high-grade":[58,165],"(<":[60],"1":[64],"2)":[66],"patients.":[67],"Parameters":[68,260],"T1,":[69,129],"T2":[70,181,194,206,225,263,281,300],"PD":[72],"values":[73,195,207,264,282,301],"SyMRI":[75,266],"obtained":[77],"on":[78],"a":[79],"GE":[80],"AW":[81],"4.7":[82],"workstation.":[83],"Continuous":[84],"variables":[85,94],"compared":[87,138,292],"by":[88],"independent-samples":[89],"t":[90],"tests,":[91],"categorical":[93],"analyzed":[96],"using":[97,139,153],"chi-square":[99],"test":[100,156],"or":[101],"Fisher's":[102],"exact":[103],"test,":[104],"appropriate.":[106],"Binary":[107],"logistic":[108,187],"regression":[109,188],"was":[110,121,137],"performed":[111],"identify":[113],"predictors":[115,198,269],"TB.":[118,201],"ROC":[119],"analysis":[120],"used":[122],"assess":[124],"predictive":[126,149],"performance":[127],"T2,":[130],"their":[132],"combined":[133,203,235],"model.":[134],"Model":[135],"fit":[136,239,289],"Akaike":[141],"information":[142],"criterion":[143],"(AIC),":[144],"calibration":[146],"overall":[148,249],"accuracy":[150,250,291],"evaluated":[152],"Hosmer-Lemeshow":[155],"Brier":[159],"score,":[160],"respectively.":[161],"RESULTS:":[162],"Compared":[163],"group,":[167],"group":[170],"showed":[171,237],"significantly":[172],"higher":[173],"T1":[174,192,204,216,261,279,298],"value":[175,182,217,226],"(p":[176,183],"<":[177,184],"0.001)":[178],"lower":[180],"0.001).":[185],"Multivariable":[186],"confirmed":[189],"that":[190,297],"both":[191],"The":[202],"model":[208,219,228,236,277,288],"achieved":[209],"AUC":[211],"0.926,":[213],"outperforming":[214],"alone":[218,227],"(AUC":[220,229],"=":[221,230,241,253],"0.883)":[222],"0.838).":[231],"In":[232],"addition,":[233],"improved":[238,287],"(AIC":[240],"72.22":[242],"vs.":[243,255],"92.77":[244],"108.18)":[246],"better":[248],"(Brier":[251],"score":[252],"0.107":[254],"0.135":[256],"0.168).":[258],"CONCLUSIONS:":[259],"are":[267],"simplified":[276],"integrating":[278],"provides":[283],"superior":[284],"discrimination":[285],"single-parameter":[294],"models,":[295],"suggesting":[296],"may":[302],"have":[303],"potential":[304],"for":[305],"noninvasive":[306],"assessment":[307],"status.":[310],"TRIAL":[311],"REGISTRATION:":[312],"Not":[313],"applicable.":[314]},"counts_by_year":[],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2026-05-19T00:00:00"}