{"id":"https://openalex.org/W7134136273","doi":"https://doi.org/10.1186/s12880-026-02257-8","title":"Three-dimensional echocardiography-derived myocardial mechanistic insights into obstructive hypertrophic cardiomyopathy with moderate septal hypertrophy","display_name":"Three-dimensional echocardiography-derived myocardial mechanistic insights into obstructive hypertrophic cardiomyopathy with moderate septal hypertrophy","publication_year":2026,"publication_date":"2026-03-07","ids":{"openalex":"https://openalex.org/W7134136273","doi":"https://doi.org/10.1186/s12880-026-02257-8","pmid":"https://pubmed.ncbi.nlm.nih.gov/41794705"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-026-02257-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02257-8","pdf_url":null,"source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12880-026-02257-8","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5128287382","display_name":"Yuwei Bao","orcid":null},"institutions":[{"id":"https://openalex.org/I4210163933","display_name":"Union Hospital","ror":"https://ror.org/055gkcy74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210163933"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuwei Bao","raw_affiliation_strings":["Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China","institution_ids":["https://openalex.org/I4210163933","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128327179","display_name":"Wei Zhou","orcid":null},"institutions":[{"id":"https://openalex.org/I4210163933","display_name":"Union Hospital","ror":"https://ror.org/055gkcy74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210163933"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Zhou","raw_affiliation_strings":["Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China","institution_ids":["https://openalex.org/I4210163933","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128280911","display_name":"Jie Tian","orcid":null},"institutions":[{"id":"https://openalex.org/I4210163933","display_name":"Union Hospital","ror":"https://ror.org/055gkcy74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210163933"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Tian","raw_affiliation_strings":["Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China","institution_ids":["https://openalex.org/I4210163933","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128286278","display_name":"Jeffrey B. Geske","orcid":null},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey B. Geske","raw_affiliation_strings":["Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I4210125099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122769295","display_name":"Si Fang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210163933","display_name":"Union Hospital","ror":"https://ror.org/055gkcy74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210163933"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Si Fang","raw_affiliation_strings":["Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China","institution_ids":["https://openalex.org/I4210163933","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122797056","display_name":"Shiliang Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210163933","display_name":"Union Hospital","ror":"https://ror.org/055gkcy74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210163933"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shiliang Liu","raw_affiliation_strings":["Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China","institution_ids":["https://openalex.org/I4210163933","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122748954","display_name":"Liming Xia","orcid":null},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liming Xia","raw_affiliation_strings":["Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101948485","display_name":"Youbin Deng","orcid":"https://orcid.org/0000-0002-3369-6855"},"institutions":[{"id":"https://openalex.org/I4210163933","display_name":"Union Hospital","ror":"https://ror.org/055gkcy74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210163933"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Youbin Deng","raw_affiliation_strings":["Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China","institution_ids":["https://openalex.org/I4210163933","https://openalex.org/I47720641"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5122808786","display_name":"Yani Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210163933","display_name":"Union Hospital","ror":"https://ror.org/055gkcy74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210163933"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yani Liu","raw_affiliation_strings":["Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China. yani.liu@163.com"],"raw_orcid":"https://orcid.org/0000-0001-5706-0811","affiliations":[{"raw_affiliation_string":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan City, Hubei Province, 43000, People's Republic of China. yani.liu@163.com","institution_ids":["https://openalex.org/I4210163933","https://openalex.org/I47720641"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5122808786"],"corresponding_institution_ids":["https://openalex.org/I4210163933","https://openalex.org/I47720641"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":{"value":2890,"currency":"USD","value_usd":2890},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.20916887,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.6481000185012817,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.6481000185012817,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.30709999799728394,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.012799999676644802,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obstructive-cardiomyopathy","display_name":"Obstructive cardiomyopathy","score":0.6118000149726868},{"id":"https://openalex.org/keywords/obstructive-hypertrophic-cardiomyopathy","display_name":"Obstructive hypertrophic cardiomyopathy","score":0.5888000130653381},{"id":"https://openalex.org/keywords/hypertrophic-cardiomyopathy","display_name":"Hypertrophic cardiomyopathy","score":0.5796999931335449},{"id":"https://openalex.org/keywords/muscle-hypertrophy","display_name":"Muscle hypertrophy","score":0.5343999862670898},{"id":"https://openalex.org/keywords/myocardial-hypertrophy","display_name":"Myocardial hypertrophy","score":0.4749000072479248},{"id":"https://openalex.org/keywords/cardiomyopathy","display_name":"Cardiomyopathy","score":0.367900013923645},{"id":"https://openalex.org/keywords/cardiac-hypertrophy","display_name":"Cardiac hypertrophy","score":0.3653999865055084}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7893999814987183},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.733299970626831},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6790000200271606},{"id":"https://openalex.org/C2909003343","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Obstructive cardiomyopathy","level":3,"score":0.6118000149726868},{"id":"https://openalex.org/C2909253254","wikidata":"https://www.wikidata.org/wiki/Q2305174","display_name":"Obstructive hypertrophic cardiomyopathy","level":4,"score":0.5888000130653381},{"id":"https://openalex.org/C2780185194","wikidata":"https://www.wikidata.org/wiki/Q1364270","display_name":"Hypertrophic cardiomyopathy","level":2,"score":0.5796999931335449},{"id":"https://openalex.org/C167414201","wikidata":"https://www.wikidata.org/wiki/Q1955391","display_name":"Muscle hypertrophy","level":2,"score":0.5343999862670898},{"id":"https://openalex.org/C3018418570","wikidata":"https://www.wikidata.org/wiki/Q1729124","display_name":"Myocardial hypertrophy","level":3,"score":0.4749000072479248},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.367900013923645},{"id":"https://openalex.org/C3018791406","wikidata":"https://www.wikidata.org/wiki/Q945225","display_name":"Cardiac hypertrophy","level":3,"score":0.3653999865055084},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.3059999942779541},{"id":"https://openalex.org/C2776835912","wikidata":"https://www.wikidata.org/wiki/Q945225","display_name":"Ventricular hypertrophy","level":4,"score":0.29330000281333923},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.2822999954223633},{"id":"https://openalex.org/C3017461755","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Myocardial ischemia","level":3,"score":0.26570001244544983},{"id":"https://openalex.org/C2776002628","wikidata":"https://www.wikidata.org/wiki/Q1628627","display_name":"Left ventricular hypertrophy","level":3,"score":0.2614000141620636},{"id":"https://openalex.org/C2780074459","wikidata":"https://www.wikidata.org/wiki/Q389735","display_name":"Heart disease","level":2,"score":0.25870001316070557},{"id":"https://openalex.org/C2777084453","wikidata":"https://www.wikidata.org/wiki/Q7452043","display_name":"Septal myectomy","level":4,"score":0.25619998574256897},{"id":"https://openalex.org/C2909789815","wikidata":"https://www.wikidata.org/wiki/Q346579","display_name":"Heart septum","level":2,"score":0.251800000667572}],"mesh":[{"descriptor_ui":"D000092242","descriptor_name":"Ventricular Outflow Obstruction, Left","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000092242","descriptor_name":"Ventricular Outflow Obstruction, Left","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000092242","descriptor_name":"Ventricular Outflow Obstruction, Left","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D000092242","descriptor_name":"Ventricular Outflow Obstruction, Left","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D000094582","descriptor_name":"Global Longitudinal Strain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000094582","descriptor_name":"Global Longitudinal Strain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006346","descriptor_name":"Heart Septum","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D006346","descriptor_name":"Heart Septum","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D006346","descriptor_name":"Heart Septum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006346","descriptor_name":"Heart Septum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019560","descriptor_name":"Echocardiography, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019560","descriptor_name":"Echocardiography, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12880-026-02257-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02257-8","pdf_url":null,"source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:41794705","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41794705","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:doaj.org/article:8878e1519fb44884b2715bdbb7826bee","is_oa":true,"landing_page_url":"https://doaj.org/article/8878e1519fb44884b2715bdbb7826bee","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 26, Iss 1 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13081521","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13081521/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Imaging","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12880-026-02257-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02257-8","pdf_url":null,"source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4883357882499695,"id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G6389436380","display_name":null,"funder_award_id":"82272109","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7240285416","display_name":null,"funder_award_id":"82472010","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W1975012641","https://openalex.org/W2055025344","https://openalex.org/W2075754886","https://openalex.org/W2097618980","https://openalex.org/W2118291118","https://openalex.org/W2128556566","https://openalex.org/W2150852004","https://openalex.org/W2159695243","https://openalex.org/W2191588938","https://openalex.org/W2336434269","https://openalex.org/W2337774029","https://openalex.org/W2341406224","https://openalex.org/W2559072822","https://openalex.org/W2727886523","https://openalex.org/W2751630023","https://openalex.org/W2765872146","https://openalex.org/W2768551579","https://openalex.org/W2795833531","https://openalex.org/W2884261065","https://openalex.org/W2905412801","https://openalex.org/W2947377711","https://openalex.org/W2983101720","https://openalex.org/W3010860473","https://openalex.org/W3081778241","https://openalex.org/W3129353006","https://openalex.org/W4281809487","https://openalex.org/W4288063454","https://openalex.org/W4292475522","https://openalex.org/W4296163600","https://openalex.org/W4367299399","https://openalex.org/W4384923473","https://openalex.org/W4385450210","https://openalex.org/W4387432042","https://openalex.org/W4390106648","https://openalex.org/W4396750647","https://openalex.org/W4402133277","https://openalex.org/W4402434871","https://openalex.org/W4407025444","https://openalex.org/W4416173463"],"related_works":[],"abstract_inverted_index":{"BACKGROUND:":[0],"In":[1,275],"hypertrophic":[2,51,277],"cardiomyopathy":[3],"(HCM)":[4],"patients":[5,48,59],"with":[6,49,60,136,211,224,261,289],"moderate":[7,50,61],"septal":[8,24,62],"hypertrophy":[9],"(\u2264":[10],"18":[11],"mm),":[12],"left":[13],"ventricular":[14],"outflow":[15],"tract":[16],"obstruction":[17,226],"(LVOTO)":[18],"cannot":[19],"be":[20],"fully":[21],"explained":[22],"by":[23],"thickness":[25],"alone,":[26],"thereby":[27],"complicating":[28],"therapeutic":[29],"decision-making.":[30],"This":[31],"study":[32],"aimed":[33],"to":[34],"investigate":[35],"the":[36,131,179,225],"association":[37],"between":[38],"three-dimensional":[39],"speckle-tracking":[40],"echocardiography":[41],"(3D-STE)-derived":[42],"myocardial":[43],"mechanics":[44,163,260,306],"and":[45,75,86,96,104,119,124,134,148,176,192,203,233,298,310,315],"LVOTO":[46,71,77,132,137,157,171,247,290,309],"in":[47,169,318],"HCM.":[52],"METHODS:":[53],"We":[54],"retrospectively":[55],"analyzed":[56,129],"216":[57],"HCM":[58],"hypertrophy,":[63],"stratified":[64],"into":[65,106,308],"nonobstructive":[66,165],"(n":[67,72,78],"=":[68,73,79,197,201,206,231,235,251,272],"38),":[69],"provokable":[70,246],"63),":[74],"resting":[76,170],"115)":[80],"groups.":[81],"LV":[82,283],"geometry,":[83],"LVOT":[84,190,213],"diameter,":[85],"anterior":[87],"mitral":[88,97],"leaflet":[89],"length":[90],"were":[91,102,128,138,178,208],"assessed":[92],"using":[93,140],"transthoracic":[94],"echocardiography,":[95],"subvalvular":[98],"papillary":[99,300],"muscle":[100,301],"abnormalities":[101],"evaluated":[103,139],"composited":[105],"a":[107],"SubMV":[108,193],"score.":[109],"3D-STE":[110,259],"quantified":[111],"strain":[112,162,280],"parameters,":[113],"including":[114,295],"global":[115],"longitudinal,":[116],"circumferential,":[117],"radial,":[118],"area":[120],"(GAS)":[121],"strain,":[122],"twist,":[123],"torsion.":[125],"Measurement":[126],"differences":[127],"among":[130],"subgroups,":[133],"associations":[135],"multivariate":[141],"regression,":[142],"restricted":[143],"cubic":[144],"spline":[145],"(RCS)":[146],"modeling,":[147],"receiver":[149],"operating":[150],"characteristic":[151],"(ROC)":[152],"curve":[153],"analysis.":[154],"RESULTS:":[155],"Both":[156],"subgroups":[158],"showed":[159,187],"significantly":[160],"augmented":[161],"versus":[164],"patients,":[166],"most":[167],"pronounced":[168],"(p":[172,182],"<":[173,183,217],"0.05).":[174,218],"Twist":[175],"torsion":[177,195,234],"strongest":[180],"discriminators":[181],"0.001).":[184],"Multivariate":[185],"regression":[186],"that,":[188],"beyond":[189,291],"diameter":[191],"score,":[194],"(B":[196,200,205],"9.47),":[198],"twist":[199,230],"1.92),":[202],"GAS":[204],"1.29)":[207],"independently":[209,287],"associated":[210,288],"provoked":[212],"gradients":[214],"(all":[215],"p":[216,271],"RCS":[219],"revealed":[220],"nonlinear":[221],"twist/torsion\u2013LVOTO":[222],"relationships,":[223],"risk":[227,313],"rising":[228],"above":[229],"15\u00b0":[232],"3\u00b0/cm,":[236],"especially":[237],"under":[238],"provocation.":[239],"Torsion":[240],"achieved":[241],"81%":[242],"specificity":[243],"for":[244],"identifying":[245],"(cutoff":[248],"2.4\u00b0/cm,":[249],"AUC":[250],"0.72),":[252],"outperforming":[253],"all":[254],"single":[255],"structural":[256,262,293],"parameters.":[257],"Integrating":[258],"metrics":[263],"improved":[264],"discrimination":[265],"(AUC":[266],"0.84":[267],"vs.":[268],"0.76,":[269],"DeLong":[270],"0.003).":[273],"CONCLUSIONS:":[274],"moderately":[276],"HCM,":[278],"3D-STE\u2013derived":[279],"mechanics,":[281,285],"particularly":[282],"torsional":[284],"are":[286],"established":[292],"parameters":[294],"anatomical":[296],"narrowing":[297],"cumulative":[299],"abnormalities.":[302],"These":[303],"findings":[304],"provide":[305],"insights":[307],"support":[311],"refined":[312],"stratification":[314],"longitudinal":[316],"monitoring":[317],"this":[319],"heterogeneous":[320],"population.":[321]},"counts_by_year":[],"updated_date":"2026-07-31T08:31:51.225901","created_date":"2026-03-08T00:00:00"}