{"id":"https://openalex.org/W7126117601","doi":"https://doi.org/10.1186/s12880-026-02191-9","title":"Development of imaging protocol and radiomics-based nomogram for assessing lesion reversibility in connective tissue disease-associated interstitial lung disease","display_name":"Development of imaging protocol and radiomics-based nomogram for assessing lesion reversibility in connective tissue disease-associated interstitial lung disease","publication_year":2026,"publication_date":"2026-01-29","ids":{"openalex":"https://openalex.org/W7126117601","doi":"https://doi.org/10.1186/s12880-026-02191-9","pmid":"https://pubmed.ncbi.nlm.nih.gov/41612222"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-026-02191-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02191-9","pdf_url":null,"source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12880-026-02191-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5124286395","display_name":"Ying Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Zhang","raw_affiliation_strings":["Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China","institution_ids":["https://openalex.org/I2800570007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124187049","display_name":"Feng Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feng Zhang","raw_affiliation_strings":["Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China","institution_ids":["https://openalex.org/I2800570007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124184772","display_name":"Huawei Wu","orcid":null},"institutions":[{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huawei Wu","raw_affiliation_strings":["Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China","institution_ids":["https://openalex.org/I2800570007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003863329","display_name":"Y. C. Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I1329325741","display_name":"Philips (Finland)","ror":"https://ror.org/01g4jev56","country_code":"FI","type":"company","lineage":["https://openalex.org/I1329325741","https://openalex.org/I4210122849"]},{"id":"https://openalex.org/I4210086647","display_name":"Philips (China)","ror":"https://ror.org/001tk4253","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210086647","https://openalex.org/I4210122849"]}],"countries":["CN","FI"],"is_corresponding":false,"raw_author_name":"Yu Wang","raw_affiliation_strings":["Clinical and Technical Support, Philips Healthcare, No.718 Lingshi Road, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Technical Support, Philips Healthcare, No.718 Lingshi Road, Shanghai, China","institution_ids":["https://openalex.org/I1329325741","https://openalex.org/I4210086647"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiao Yu","orcid":null},"institutions":[{"id":"https://openalex.org/I1329325741","display_name":"Philips (Finland)","ror":"https://ror.org/01g4jev56","country_code":"FI","type":"company","lineage":["https://openalex.org/I1329325741","https://openalex.org/I4210122849"]},{"id":"https://openalex.org/I4210086647","display_name":"Philips (China)","ror":"https://ror.org/001tk4253","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210086647","https://openalex.org/I4210122849"]}],"countries":["CN","FI"],"is_corresponding":false,"raw_author_name":"Xiao Yu","raw_affiliation_strings":["Clinical and Technical Support, Philips Healthcare, No.718 Lingshi Road, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Technical Support, Philips Healthcare, No.718 Lingshi Road, Shanghai, China","institution_ids":["https://openalex.org/I1329325741","https://openalex.org/I4210086647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124239264","display_name":"Shusen Lin","orcid":null},"institutions":[{"id":"https://openalex.org/I4210151799","display_name":"Siemens Healthcare (United States)","ror":"https://ror.org/054962n91","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151799"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shusen Lin","raw_affiliation_strings":["Siemens Healthineers China, No.399 West Haiyang Road, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Siemens Healthineers China, No.399 West Haiyang Road, Shanghai, China","institution_ids":["https://openalex.org/I4210151799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100421117","display_name":"Yu Ye","orcid":"https://orcid.org/0000-0002-8820-1805"},"institutions":[{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ye Yu","raw_affiliation_strings":["Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China","institution_ids":["https://openalex.org/I2800570007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124266960","display_name":"Jiaxu Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiaxu Wei","raw_affiliation_strings":["Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China","institution_ids":["https://openalex.org/I2800570007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5124156349","display_name":"Yan Zhou","orcid":null},"institutions":[{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yan Zhou","raw_affiliation_strings":["Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China. renjizy@163.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology Department, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, China. renjizy@163.com","institution_ids":["https://openalex.org/I2800570007"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5124156349"],"corresponding_institution_ids":["https://openalex.org/I2800570007"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.09288422,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":0.9010999798774719,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":0.9010999798774719,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.0203000009059906,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.007799999788403511,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nomogram","display_name":"Nomogram","score":0.8567000031471252},{"id":"https://openalex.org/keywords/lesion","display_name":"Lesion","score":0.59170001745224},{"id":"https://openalex.org/keywords/interquartile-range","display_name":"Interquartile range","score":0.5281999707221985},{"id":"https://openalex.org/keywords/lung","display_name":"Lung","score":0.5144000053405762},{"id":"https://openalex.org/keywords/interstitial-lung-disease","display_name":"Interstitial lung disease","score":0.44929999113082886},{"id":"https://openalex.org/keywords/cohort","display_name":"Cohort","score":0.4205000102519989},{"id":"https://openalex.org/keywords/radiomics","display_name":"Radiomics","score":0.3885999917984009},{"id":"https://openalex.org/keywords/medical-diagnosis","display_name":"Medical diagnosis","score":0.36550000309944153}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9276999831199646},{"id":"https://openalex.org/C34626388","wikidata":"https://www.wikidata.org/wiki/Q721129","display_name":"Nomogram","level":2,"score":0.8567000031471252},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.6330999732017517},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.59170001745224},{"id":"https://openalex.org/C119060515","wikidata":"https://www.wikidata.org/wiki/Q1916617","display_name":"Interquartile range","level":2,"score":0.5281999707221985},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.5144000053405762},{"id":"https://openalex.org/C2777543607","wikidata":"https://www.wikidata.org/wiki/Q1153419","display_name":"Interstitial lung disease","level":3,"score":0.44929999113082886},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4205000102519989},{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.3885999917984009},{"id":"https://openalex.org/C534262118","wikidata":"https://www.wikidata.org/wiki/Q177719","display_name":"Medical diagnosis","level":2,"score":0.36550000309944153},{"id":"https://openalex.org/C518705261","wikidata":"https://www.wikidata.org/wiki/Q25615","display_name":"Connective tissue","level":2,"score":0.35580000281333923},{"id":"https://openalex.org/C2776670291","wikidata":"https://www.wikidata.org/wiki/Q1779300","display_name":"Connective tissue disease","level":4,"score":0.34130001068115234},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.34060001373291016},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.28790000081062317},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.28459998965263367},{"id":"https://openalex.org/C36454342","wikidata":"https://www.wikidata.org/wiki/Q245341","display_name":"Radiography","level":2,"score":0.2840000092983246},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.26579999923706055},{"id":"https://openalex.org/C2778822529","wikidata":"https://www.wikidata.org/wiki/Q1951525","display_name":"Progressive disease","level":3,"score":0.26080000400543213},{"id":"https://openalex.org/C2779701055","wikidata":"https://www.wikidata.org/wiki/Q929833","display_name":"Rare disease","level":3,"score":0.2572000026702881},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.25699999928474426},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.2556999921798706}],"mesh":[{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003240","descriptor_name":"Connective Tissue Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D003240","descriptor_name":"Connective Tissue Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D003240","descriptor_name":"Connective Tissue Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D003240","descriptor_name":"Connective Tissue Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D049451","descriptor_name":"Nomograms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049451","descriptor_name":"Nomograms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12880-026-02191-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02191-9","pdf_url":null,"source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:41612222","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41612222","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:doaj.org/article:48302cfde4674f0bb72df90f9778413b","is_oa":true,"landing_page_url":"https://doaj.org/article/48302cfde4674f0bb72df90f9778413b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 26, Iss 1 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12924472","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12924472/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Imaging","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12880-026-02191-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-026-02191-9","pdf_url":null,"source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.40639039874076843,"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1996259839","https://openalex.org/W2123443669","https://openalex.org/W2137041181","https://openalex.org/W2144454047","https://openalex.org/W2151308085","https://openalex.org/W2165771235","https://openalex.org/W2173908789","https://openalex.org/W2226560771","https://openalex.org/W2416914730","https://openalex.org/W2477244836","https://openalex.org/W2592551118","https://openalex.org/W2612247065","https://openalex.org/W2897712575","https://openalex.org/W3006532268","https://openalex.org/W3007003780","https://openalex.org/W3091974947","https://openalex.org/W3109038980","https://openalex.org/W3120653784","https://openalex.org/W3191425764","https://openalex.org/W3207444453","https://openalex.org/W3207754336","https://openalex.org/W3211749461","https://openalex.org/W3215384057","https://openalex.org/W4283323360","https://openalex.org/W4285498943","https://openalex.org/W4313890063","https://openalex.org/W4392191246","https://openalex.org/W4410268406","https://openalex.org/W4413440608","https://openalex.org/W4416746830"],"related_works":[],"abstract_inverted_index":{"BACKGROUND:":[0],"Assessing":[1],"the":[2,93,109,132,135,236,241,254,264,268],"reversibility":[3,38,121,283,301],"of":[4,66,77,153,164],"connective":[5],"tissue":[6],"disease":[7,11],"associated":[8],"interstitial":[9],"lung":[10,130,219],"(CTD-ILD)":[12],"is":[13],"critical":[14],"for":[15,309],"treatment":[16,307],"decision-making,":[17],"yet":[18],"standardized":[19],"imaging":[20,279],"criteria":[21],"and":[22,39,80,87,101,111,171,179,189,212,270,285,293],"baseline":[23,47,142,154,165],"predictive":[24],"tools":[25],"remain":[26],"limited.":[27],"We":[28,50,275],"aimed":[29],"to":[30,35,45,185,281],"establish":[31],"a":[32,41,74,277,287],"CT-based":[33],"protocol":[34,280],"determine":[36],"lesion":[37,137,300],"develop":[40,186],"combined":[42,190,251,288],"radiomics\u2013morphology":[43],"nomogram":[44,191,252,289],"predict":[46],"reversibility.":[48],"METHODS:":[49],"retrospectively":[51],"analyzed":[52],"consecutive":[53],"CTD-ILD":[54,69,310],"patients":[55,107,199,224],"(January":[56],"2016\u2013June":[57],"2022,":[58],"diagnosed":[59],"via":[60],"ACR/EULAR":[61],"criteria)":[62],"from":[63,92,108],"three":[64],"branches":[65],"Renji":[67],"Hospital.":[68],"diagnoses":[70],"were":[71,96,148,183],"established":[72,276],"by":[73],"multidisciplinary":[75],"team":[76],"respiratory":[78],"physicians":[79],"thoracic":[81],"radiologists":[82],"based":[83],"on":[84,156,167],"clinical":[85],"manifestations":[86],"chest":[88],"CT":[89,126,181],"imaging.":[90],"Patients":[91],"South":[94],"Branch":[95],"randomly":[97],"split":[98],"into":[99],"training":[100,269],"internal":[102],"validation":[103,118,272],"cohorts":[104],"(7:3),":[105],"while":[106,240],"East":[110],"West":[112],"Branches":[113],"formed":[114],"an":[115],"independent":[116],"external":[117,271],"cohort.":[119],"Lesion":[120],"was":[122,139],"adjudicated":[123],"using":[124],"longitudinal":[125,278],"series":[127],"across":[128],"six":[129],"zones:":[131],"scan":[133],"with":[134,208,216,260],"greatest":[136],"extent":[138],"defined":[140,149],"as":[141,150],"(CT0);":[143],"completely":[144],"reversible":[145],"(CR)":[146],"lesions":[147,155,166],"complete":[151],"absorption":[152],"any":[157],"follow-up":[158,174],"CT,":[159],"whereas":[160],"non-CR":[161],"required":[162],"persistence":[163],"both":[168],"3\u20136-month":[169],"(CTF1)":[170],"12-month":[172],"(CTF2)":[173],"CTs.":[175],"Zonal-level":[176],"radiomics":[177,229],"signatures":[178],"visual":[180,242,265,294],"features":[182],"used":[184],"radiomics,":[187],"visual,":[188],"models.":[192],"RESULTS:":[193],"The":[194,228,250],"final":[195],"cohort":[196],"included":[197],"153":[198],"(median":[200],"age,":[201],"53":[202],"years;":[203],"interquartile":[204],"range,":[205],"44\u201362":[206],"years),":[207],"40":[209],"males":[210],"(26.1%)":[211],"113":[213],"females":[214],"(73.9%)":[215],"575":[217],"affected":[218],"zones.":[220],"Cohorts":[221],"comprised":[222],"66/28/59":[223],"(training/internal":[225],"validation/external":[226],"validation).":[227],"model":[230,243,266],"showed":[231],"moderate":[232],"discrimination":[233],"(areas":[234],"under":[235],"curve":[237],"[AUCs]":[238],"0.72/0.77/0.73),":[239],"performed":[244],"similarly":[245],"or":[246],"better":[247],"(AUCs":[248,258],"0.82/0.87/0.78).":[249],"achieved":[253],"best":[255],"overall":[256],"performance":[257],"0.86/0.90/0.82),":[259],"significant":[261],"improvement":[262],"over":[263],"in":[267],"cohorts.":[273],"CONCLUSION:":[274],"standardize":[282],"assessment":[284],"validated":[286],"that":[290],"integrates":[291],"quantitative":[292],"data.":[295],"This":[296],"tool":[297],"accurately":[298],"predicts":[299],"at":[302],"baseline,":[303],"potentially":[304],"facilitating":[305],"personalized":[306],"strategies":[308],"patients.":[311]},"counts_by_year":[],"updated_date":"2026-02-21T06:11:54.161237","created_date":"2026-01-30T00:00:00"}