{"id":"https://openalex.org/W7117478682","doi":"https://doi.org/10.1186/s12880-025-02060-x","title":"An interpretable machine learning model based on CT imaging for predicting lymphovascular invasion and survival in bladder urothelial carcinoma: a multicenter study","display_name":"An interpretable machine learning model based on CT imaging for predicting lymphovascular invasion and survival in bladder urothelial carcinoma: a multicenter study","publication_year":2025,"publication_date":"2025-12-29","ids":{"openalex":"https://openalex.org/W7117478682","doi":"https://doi.org/10.1186/s12880-025-02060-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/41462442"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-025-02060-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-02060-x","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12880-025-02060-x.pdf","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s12880-025-02060-x.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101381997","display_name":"Bangxin Xiao","orcid":null},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bangxin Xiao","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I4210129459","https://openalex.org/I87780372"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Qiyuan Zeng","orcid":null},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiyuan Zeng","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I4210129459","https://openalex.org/I87780372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121468476","display_name":"Xiang Peng","orcid":null},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiang Peng","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I4210129459","https://openalex.org/I87780372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102641321","display_name":"Quanhao He","orcid":"https://orcid.org/0000-0002-8231-8199"},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Quanhao He","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I4210129459","https://openalex.org/I87780372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070875792","display_name":"Yingjie Xv","orcid":"https://orcid.org/0000-0001-5585-6058"},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingjie Xv","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I4210129459","https://openalex.org/I87780372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003432921","display_name":"Zongjie Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I4210156877","display_name":"Second People\u2019s Hospital of Yibin","ror":"https://ror.org/05xceke97","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156877"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zongjie Wei","raw_affiliation_strings":["Department of Urology, Yibin Second People's Hospital, Yibin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Yibin Second People's Hospital, Yibin, China","institution_ids":["https://openalex.org/I4210156877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117585429","display_name":"Qiao Xv","orcid":null},"institutions":[{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiao Xv","raw_affiliation_strings":["Department of Urology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I87780372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121450206","display_name":"Fajin Lv","orcid":null},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fajin Lv","raw_affiliation_strings":["Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I4210129459","https://openalex.org/I87780372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121489137","display_name":"Qing Jiang","orcid":null},"institutions":[{"id":"https://openalex.org/I191996457","display_name":"Dalian Medical University","ror":"https://ror.org/04c8eg608","country_code":"CN","type":"education","lineage":["https://openalex.org/I191996457"]},{"id":"https://openalex.org/I4210097509","display_name":"Second Affiliated Hospital of Chongqing Medical University","ror":"https://ror.org/00r67fz39","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097509"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qing Jiang","raw_affiliation_strings":["Department of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I191996457","https://openalex.org/I87780372","https://openalex.org/I4210097509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100579616","display_name":"Shaman Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I4210108305","display_name":"Chongqing Maternal and Child Health Hospital","ror":"https://ror.org/01tt8er74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108305"]},{"id":"https://openalex.org/I4210159428","display_name":"Children's Hospital of Chongqing Medical University","ror":"https://ror.org/05pz4ws32","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159428"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shaman Wei","raw_affiliation_strings":["Center for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China. shamanhaimian@163.com","Chongqing Clinical Research Center for Reproductive Medicine, Chongqing Health Center for Women and Children, Chongqing, China. shamanhaimian@163.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China. shamanhaimian@163.com","institution_ids":["https://openalex.org/I87780372","https://openalex.org/I4210159428"]},{"raw_affiliation_string":"Chongqing Clinical Research Center for Reproductive Medicine, Chongqing Health Center for Women and Children, Chongqing, China. shamanhaimian@163.com","institution_ids":["https://openalex.org/I4210108305"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110676992","display_name":"Mingzhao Xiao","orcid":null},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingzhao Xiao","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. mingzhaoxiao@cqmu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. mingzhaoxiao@cqmu.edu.cn","institution_ids":["https://openalex.org/I4210129459","https://openalex.org/I87780372"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5101381997"],"corresponding_institution_ids":["https://openalex.org/I4210129459","https://openalex.org/I87780372"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.71489917,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"25","issue":"1","first_page":"513","last_page":"513"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.8622999787330627,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.8622999787330627,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.02449999935925007,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.011699999682605267,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multicenter-study","display_name":"Multicenter study","score":0.7523000240325928},{"id":"https://openalex.org/keywords/radiomics","display_name":"Radiomics","score":0.7330999970436096},{"id":"https://openalex.org/keywords/lymphovascular-invasion","display_name":"Lymphovascular invasion","score":0.574400007724762},{"id":"https://openalex.org/keywords/informed-consent","display_name":"Informed consent","score":0.5333999991416931},{"id":"https://openalex.org/keywords/multidetector-computed-tomography","display_name":"Multidetector computed tomography","score":0.43070000410079956},{"id":"https://openalex.org/keywords/ethics-committee","display_name":"Ethics committee","score":0.40939998626708984},{"id":"https://openalex.org/keywords/institutional-review-board","display_name":"Institutional review board","score":0.40610000491142273},{"id":"https://openalex.org/keywords/retrospective-cohort-study","display_name":"Retrospective cohort study","score":0.3797999918460846}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7760999798774719},{"id":"https://openalex.org/C2992435398","wikidata":"https://www.wikidata.org/wiki/Q6934595","display_name":"Multicenter study","level":3,"score":0.7523000240325928},{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.7330999970436096},{"id":"https://openalex.org/C2778740770","wikidata":"https://www.wikidata.org/wiki/Q6708283","display_name":"Lymphovascular invasion","level":4,"score":0.574400007724762},{"id":"https://openalex.org/C68122502","wikidata":"https://www.wikidata.org/wiki/Q764527","display_name":"Informed consent","level":3,"score":0.5333999991416931},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5163999795913696},{"id":"https://openalex.org/C2993154269","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Multidetector computed tomography","level":3,"score":0.43070000410079956},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.41920000314712524},{"id":"https://openalex.org/C2776970089","wikidata":"https://www.wikidata.org/wiki/Q27913684","display_name":"Ethics committee","level":2,"score":0.40939998626708984},{"id":"https://openalex.org/C2777106319","wikidata":"https://www.wikidata.org/wiki/Q362104","display_name":"Institutional review board","level":2,"score":0.40610000491142273},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.3797999918460846},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.37560001015663147},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.3553999960422516},{"id":"https://openalex.org/C544519230","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Computed tomography","level":2,"score":0.3528999984264374},{"id":"https://openalex.org/C153997805","wikidata":"https://www.wikidata.org/wiki/Q42240","display_name":"Research ethics","level":2,"score":0.3075999915599823},{"id":"https://openalex.org/C3019882237","wikidata":"https://www.wikidata.org/wiki/Q2501186","display_name":"Urothelial carcinoma","level":4,"score":0.29989999532699585},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.29490000009536743},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.2840999960899353},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.28189998865127563},{"id":"https://openalex.org/C529618451","wikidata":"https://www.wikidata.org/wiki/Q234904","display_name":"Ultrasonography","level":2,"score":0.2815999984741211},{"id":"https://openalex.org/C3019894029","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Overall survival","level":2,"score":0.2770000100135803},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.2750000059604645},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.2587999999523163}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015653","descriptor_name":"Cystectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015653","descriptor_name":"Cystectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015653","descriptor_name":"Cystectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015653","descriptor_name":"Cystectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12880-025-02060-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-02060-x","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12880-025-02060-x.pdf","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:41462442","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41462442","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:doaj.org/article:bd50d4c8884a4b32b942c9dcc528739e","is_oa":true,"landing_page_url":"https://doaj.org/article/bd50d4c8884a4b32b942c9dcc528739e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 25, Iss 1, Pp 1-13 (2025)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12751532","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12751532/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Imaging","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12880-025-02060-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-02060-x","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12880-025-02060-x.pdf","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.41473740339279175,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G4870744778","display_name":null,"funder_award_id":"CYYY-DSTDXM-202409","funder_id":"https://openalex.org/F4320322595","funder_display_name":"Chongqing Medical University"}],"funders":[{"id":"https://openalex.org/F4320322595","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7117478682.pdf","grobid_xml":"https://content.openalex.org/works/W7117478682.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1968365510","https://openalex.org/W1987639526","https://openalex.org/W2020531505","https://openalex.org/W2020976393","https://openalex.org/W2049515197","https://openalex.org/W2049710699","https://openalex.org/W2071272359","https://openalex.org/W2119109423","https://openalex.org/W2164589152","https://openalex.org/W2174661749","https://openalex.org/W2463498486","https://openalex.org/W2592749763","https://openalex.org/W2612463896","https://openalex.org/W2763355946","https://openalex.org/W2783375881","https://openalex.org/W2795247859","https://openalex.org/W2803043616","https://openalex.org/W2987800544","https://openalex.org/W2999800225","https://openalex.org/W3087999556","https://openalex.org/W3215419511","https://openalex.org/W4200007618","https://openalex.org/W4229449094","https://openalex.org/W4294675960","https://openalex.org/W4297102182","https://openalex.org/W4317033174","https://openalex.org/W4382984118","https://openalex.org/W4385406883","https://openalex.org/W4386142022","https://openalex.org/W4388014597","https://openalex.org/W4391588936","https://openalex.org/W4392110035","https://openalex.org/W4408295908","https://openalex.org/W4408490737","https://openalex.org/W4410468867","https://openalex.org/W4410955366","https://openalex.org/W4413270242"],"related_works":[],"abstract_inverted_index":{"BACKGROUND:":[0],"Lymphovascular":[1],"invasion":[2],"(LVI)":[3],"is":[4],"a":[5],"critical":[6],"prognostic":[7],"factor":[8,175],"in":[9,55,160,166,183,189,259],"bladder":[10,58,260],"cancer,":[11],"affecting":[12],"recurrence,":[13],"survival,":[14],"and":[15,29,52,78,91,96,103,145,164,187,212,256,289],"overall":[16],"prognosis.":[17],"Traditional":[18],"methods":[19],"for":[20],"diagnosing":[21],"LVI,":[22,207],"such":[23,208],"as":[24,209],"immunohistochemical":[25],"staining,":[26],"are":[27],"costly":[28],"time-consuming,":[30],"making":[31],"non-invasive":[32],"alternatives":[33],"like":[34],"radiomics-based":[35],"models":[36],"valuable.":[37],"This":[38,66,236,265],"study":[39,67,238,266],"aimed":[40],"to":[41,48,220,229,232],"construct":[42],"an":[43,156,179],"interpretable":[44,242],"machine":[45,111,243],"learning":[46,112,244],"model":[47,123,151,172,245],"predict":[49,253],"LVI":[50,254],"status":[51,255],"survival":[53,146,227,257],"outcomes":[54,258],"patients":[56,70,218,230],"with":[57,71,132,155,206],"urothelial":[59,72,261],"carcinoma":[60,73],"using":[61,118,198],"preoperative":[62,79,248],"CT":[63,81,249],"images.":[64],"METHODS:":[65],"retrospectively":[68,268],"enrolled":[69],"who":[74],"underwent":[75],"radical":[76],"cystectomy":[77],"contrast-enhanced":[80],"from":[82],"three":[83],"medicine":[84],"centers.":[85],"Tumor":[86],"regions":[87],"were":[88,94,116],"manually":[89],"segmented,":[90],"radiomics":[92,109,130,203],"features":[93,204],"extracted":[95],"selected":[97,108],"through":[98],"reproducibility":[99],"testing,":[100],"correlation":[101],"analysis,":[102,200],"LASSO.":[104],"Based":[105],"on":[106,247,285],"the":[107,129,161,167,184,190,241,274],"features,":[110],"classifiers,":[113],"including":[114],"SVM,":[115],"trained":[117],"five-fold":[119],"cross-validation.":[120],"A":[121],"combined":[122,171],"was":[124,138,196,267,292],"then":[125],"constructed":[126],"by":[127,140,270],"integrating":[128,173],"signature":[131],"clinical":[133,174],"risk":[134],"factors.":[135],"Model":[136],"performance":[137],"evaluated":[139],"AUC,":[141],"ACC,":[142],"sensitivity,":[143],"specificity,":[144],"analysis.":[147],"RESULTS:":[148],"The":[149,170,193],"SVM":[150],"showed":[152],"high":[153],"performance,":[154],"AUC":[157,180],"of":[158,181,273,278],"0.944":[159],"training":[162,185],"set":[163,186],"0.872":[165],"testing":[168,191],"set.":[169,192],"performed":[176],"better,":[177],"achieving":[178],"0.952":[182],"0.901":[188],"model's":[194],"interpretability":[195],"enhanced":[197],"SHAP":[199],"identifying":[201],"key":[202],"associated":[205],"tumor":[210],"shape":[211],"texture.":[213],"Survival":[214],"analysis":[215],"indicated":[216],"that":[217,240],"predicted":[219,231],"be":[221,233],"LVI-negative":[222],"had":[223],"significantly":[224],"better":[225],"disease-free":[226],"compared":[228],"LVI-positive.":[234],"CONCLUSIONS:":[235],"multicenter":[237],"demonstrates":[239],"based":[246],"images":[250],"can":[251],"effectively":[252],"carcinoma.":[262],"TRIAL":[263],"REGISTRATION:":[264],"registered":[269],"Ethics":[271],"Committee":[272],"First":[275],"Affiliated":[276],"Hospital":[277],"Chongqing":[279],"Medical":[280],"University":[281],"(Approval":[282],"No.":[283],"K2024-187-01)":[284],"April":[286],"12,":[287],"2024,":[288],"informed":[290],"consent":[291],"waived.":[293]},"counts_by_year":[],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-12-29T00:00:00"}