{"id":"https://openalex.org/W4416146104","doi":"https://doi.org/10.1186/s12880-025-02012-5","title":"Radiomic imaging models for predicting breast cancer prognosis based on Interleukin-18 (IL18)","display_name":"Radiomic imaging models for predicting breast cancer prognosis based on Interleukin-18 (IL18)","publication_year":2025,"publication_date":"2025-11-12","ids":{"openalex":"https://openalex.org/W4416146104","doi":"https://doi.org/10.1186/s12880-025-02012-5","pmid":"https://pubmed.ncbi.nlm.nih.gov/41225352"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-025-02012-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-02012-5","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-02012-5","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-02012-5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067112477","display_name":"Qian Zhou","orcid":"https://orcid.org/0000-0001-7890-0664"},"institutions":[{"id":"https://openalex.org/I4210090625","display_name":"Nanjing Children's Hospital","ror":"https://ror.org/000xvke80","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090625"]},{"id":"https://openalex.org/I4210100029","display_name":"Nanjing Maternity and Child Health Care Hospital","ror":"https://ror.org/01a2gef28","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100029"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qian Zhou","raw_affiliation_strings":["Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China","institution_ids":["https://openalex.org/I4210100029","https://openalex.org/I4210090625"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033699442","display_name":"Mie Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I4210090625","display_name":"Nanjing Children's Hospital","ror":"https://ror.org/000xvke80","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090625"]},{"id":"https://openalex.org/I4210100029","display_name":"Nanjing Maternity and Child Health Care Hospital","ror":"https://ror.org/01a2gef28","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100029"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mie Chen","raw_affiliation_strings":["Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China","institution_ids":["https://openalex.org/I4210100029","https://openalex.org/I4210090625"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010278056","display_name":"Xiaojing Ye","orcid":"https://orcid.org/0000-0003-4673-3763"},"institutions":[{"id":"https://openalex.org/I4210090625","display_name":"Nanjing Children's Hospital","ror":"https://ror.org/000xvke80","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090625"]},{"id":"https://openalex.org/I4210100029","display_name":"Nanjing Maternity and Child Health Care Hospital","ror":"https://ror.org/01a2gef28","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100029"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiahui Ye","raw_affiliation_strings":["Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China","institution_ids":["https://openalex.org/I4210100029","https://openalex.org/I4210090625"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100741636","display_name":"Jie Wang","orcid":"https://orcid.org/0009-0009-3629-4542"},"institutions":[{"id":"https://openalex.org/I4210090625","display_name":"Nanjing Children's Hospital","ror":"https://ror.org/000xvke80","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090625"]},{"id":"https://openalex.org/I4210100029","display_name":"Nanjing Maternity and Child Health Care Hospital","ror":"https://ror.org/01a2gef28","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100029"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Wang","raw_affiliation_strings":["Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China","institution_ids":["https://openalex.org/I4210100029","https://openalex.org/I4210090625"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101444311","display_name":"Xun Lu","orcid":"https://orcid.org/0000-0003-3082-613X"},"institutions":[{"id":"https://openalex.org/I4210117216","display_name":"Jiangsu Provincial Center for Disease Control and Prevention","ror":"https://ror.org/02ey6qs66","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210117216"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xun Lu","raw_affiliation_strings":["Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, 210009, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, 210009, China","institution_ids":["https://openalex.org/I4210117216"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053920108","display_name":"Wenjie Shi","orcid":"https://orcid.org/0000-0002-7564-3057"},"institutions":[{"id":"https://openalex.org/I4210090625","display_name":"Nanjing Children's Hospital","ror":"https://ror.org/000xvke80","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090625"]},{"id":"https://openalex.org/I4210100029","display_name":"Nanjing Maternity and Child Health Care Hospital","ror":"https://ror.org/01a2gef28","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100029"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenjie Shi","raw_affiliation_strings":["Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China","institution_ids":["https://openalex.org/I4210100029","https://openalex.org/I4210090625"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101143670","display_name":"Lu Cheng","orcid":null},"institutions":[{"id":"https://openalex.org/I4210090625","display_name":"Nanjing Children's Hospital","ror":"https://ror.org/000xvke80","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090625"]},{"id":"https://openalex.org/I4210100029","display_name":"Nanjing Maternity and Child Health Care Hospital","ror":"https://ror.org/01a2gef28","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100029"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cheng Lu","raw_affiliation_strings":["Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China","institution_ids":["https://openalex.org/I4210100029","https://openalex.org/I4210090625"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112196042","display_name":"Hong Yin","orcid":"https://orcid.org/0000-0002-2973-3801"},"institutions":[{"id":"https://openalex.org/I4210090625","display_name":"Nanjing Children's Hospital","ror":"https://ror.org/000xvke80","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090625"]},{"id":"https://openalex.org/I4210100029","display_name":"Nanjing Maternity and Child Health Care Hospital","ror":"https://ror.org/01a2gef28","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100029"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Yin","raw_affiliation_strings":["Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China. yh_njfy@163.com","Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China. yh_njfy@163.com","institution_ids":["https://openalex.org/I4210100029"]},{"raw_affiliation_string":"Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), Nanjing, 210004, China","institution_ids":["https://openalex.org/I4210100029","https://openalex.org/I4210090625"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.43877178,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"25","issue":"1","first_page":"460","last_page":"460"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.6466000080108643,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.6466000080108643,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14245","display_name":"Biomarkers in Disease Mechanisms","score":0.03720000013709068,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.026599999517202377,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiomics","display_name":"Radiomics","score":0.756600022315979},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.6876000165939331},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.503600001335144},{"id":"https://openalex.org/keywords/cancer-imaging","display_name":"Cancer imaging","score":0.46889999508857727},{"id":"https://openalex.org/keywords/breast-imaging","display_name":"Breast imaging","score":0.453900009393692},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.4099999964237213},{"id":"https://openalex.org/keywords/breast-mri","display_name":"Breast MRI","score":0.3427000045776367}],"concepts":[{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.756600022315979},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6876000165939331},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6557999849319458},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.503600001335144},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4943999946117401},{"id":"https://openalex.org/C2994114330","wikidata":"https://www.wikidata.org/wiki/Q5031437","display_name":"Cancer imaging","level":3,"score":0.46889999508857727},{"id":"https://openalex.org/C2777432617","wikidata":"https://www.wikidata.org/wiki/Q22905905","display_name":"Breast imaging","level":5,"score":0.453900009393692},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.4099999964237213},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.3481000065803528},{"id":"https://openalex.org/C2777111374","wikidata":"https://www.wikidata.org/wiki/Q4959770","display_name":"Breast MRI","level":5,"score":0.3427000045776367},{"id":"https://openalex.org/C544519230","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Computed tomography","level":2,"score":0.3301999866962433},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.31299999356269836},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3046000003814697},{"id":"https://openalex.org/C2780472235","wikidata":"https://www.wikidata.org/wiki/Q324634","display_name":"Mammography","level":4,"score":0.3034000098705292},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.28600001335144043},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2833000123500824},{"id":"https://openalex.org/C3018130915","wikidata":"https://www.wikidata.org/wiki/Q1752284","display_name":"Neoplasm staging","level":3,"score":0.2728999853134155},{"id":"https://openalex.org/C71472368","wikidata":"https://www.wikidata.org/wiki/Q676880","display_name":"Text mining","level":2,"score":0.2653000056743622},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.26190000772476196},{"id":"https://openalex.org/C529618451","wikidata":"https://www.wikidata.org/wiki/Q234904","display_name":"Ultrasonography","level":2,"score":0.26109999418258667}],"mesh":[{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020382","descriptor_name":"Interleukin-18","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020382","descriptor_name":"Interleukin-18","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020382","descriptor_name":"Interleukin-18","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020382","descriptor_name":"Interleukin-18","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020382","descriptor_name":"Interleukin-18","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020382","descriptor_name":"Interleukin-18","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020382","descriptor_name":"Interleukin-18","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020382","descriptor_name":"Interleukin-18","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12880-025-02012-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-02012-5","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-02012-5","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:41225352","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41225352","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:doaj.org/article:25dca8ca7bab4b709aba672ee6fb7918","is_oa":true,"landing_page_url":"https://doaj.org/article/25dca8ca7bab4b709aba672ee6fb7918","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 25, Iss 1, Pp 1-15 (2025)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:11421703","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12613398","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12880-025-02012-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-02012-5","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-02012-5","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4416146104.pdf","grobid_xml":"https://content.openalex.org/works/W4416146104.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W184793361","https://openalex.org/W1578104218","https://openalex.org/W1603808379","https://openalex.org/W1984414393","https://openalex.org/W2000477356","https://openalex.org/W2012781730","https://openalex.org/W2030238365","https://openalex.org/W2044094475","https://openalex.org/W2054155260","https://openalex.org/W2081415962","https://openalex.org/W2106359295","https://openalex.org/W2121369239","https://openalex.org/W2154327847","https://openalex.org/W2166454467","https://openalex.org/W2244253213","https://openalex.org/W2338137334","https://openalex.org/W2547350594","https://openalex.org/W2607211817","https://openalex.org/W2795921326","https://openalex.org/W2796896165","https://openalex.org/W2904291170","https://openalex.org/W2968063452","https://openalex.org/W2971028656","https://openalex.org/W3005889306","https://openalex.org/W3013389750","https://openalex.org/W3157179041","https://openalex.org/W3163533590","https://openalex.org/W3196720363","https://openalex.org/W4211013386","https://openalex.org/W4214920103","https://openalex.org/W4220939811","https://openalex.org/W4283071205","https://openalex.org/W4289524080","https://openalex.org/W4292675392","https://openalex.org/W4294216483","https://openalex.org/W4307824594","https://openalex.org/W4379618674","https://openalex.org/W4386134044","https://openalex.org/W4387496504","https://openalex.org/W4394011983","https://openalex.org/W4395068214","https://openalex.org/W4399470315","https://openalex.org/W4399721741","https://openalex.org/W4403042467","https://openalex.org/W4404404312","https://openalex.org/W4406085296","https://openalex.org/W4406459740","https://openalex.org/W4410313255"],"related_works":[],"abstract_inverted_index":{"OBJECTIVE:":[0],"Our":[1],"study":[2],"was":[3,55],"aimed":[4],"to":[5,23,41,57,70],"established":[6,37,122],"imaging":[7],"models":[8,40,150],"that":[9],"can":[10,151],"predict":[11,42],"the":[12,25,33,43,59,72,80,133],"prognosis":[13,134,171],"of":[14,27,46,61,90,135,161,172],"breast":[15,49,64,85,136,146,173],"cancer":[16,50,65,86,137,174],"patients":[17],"based":[18],"on":[19],"IL18,":[20],"so":[21],"as":[22,153],"facilitate":[24],"formulation":[26],"more":[28],"individualized":[29],"treatment":[30],"plans":[31],"during":[32],"treatment.":[34],"METHOD:":[35],"We":[36],"enhancing":[38,164],"MRI":[39,165],"mRNA":[44,159],"expression":[45,60,92,160],"IL18":[47,62,91,140,162],"in":[48,63,123,132,145,169],"tissues.":[51],"Meanwhile,":[52],"bioinformatics":[53],"analysis":[54],"integrated":[56],"studied":[58],"with":[66,79,95,111],"its":[67,77],"clinical":[68],"significance":[69],"explore":[71],"potential":[73],"molecular":[74],"mechanisms":[75],"and":[76,100,119,166],"association":[78],"immune":[81],"microenvironment.":[82],"RESULT:":[83],"In":[84],"patients,":[87],"high":[88],"levels":[89],"are":[93],"associated":[94],"improved":[96],"overall":[97],"survival":[98],"(OS),":[99],"natural":[101],"killer":[102],"cells":[103],"(NK":[104],"cells)":[105],"significantly":[106],"increased":[107],"(P":[108],"<":[109],"0.001)":[110],"elevated":[112],"IL18.":[113],"Three":[114],"radiomics":[115,149],"models,":[116],"RFE-GBM,":[117],"Relief-GBM,":[118],"RFE_Relief-GBM":[120],"were":[121],"our":[124,148],"study,":[125],"each":[126],"model":[127],"demonstrated":[128],"strong":[129],"predictive":[130],"consistency":[131],"patients.":[138,175],"CONCLUSION:":[139],"is":[141],"a":[142],"protective":[143],"factor":[144],"cancer,":[147],"serve":[152],"valuable":[154],"non-invasive":[155],"tools":[156],"for":[157],"utilizing":[158],"by":[163],"show":[167],"promise":[168],"predicting":[170],"CLINICAL":[176],"TRIAL":[177],"NUMBER:":[178],"Not":[179],"applicable.":[180]},"counts_by_year":[],"updated_date":"2026-03-13T14:20:09.374765","created_date":"2025-11-12T00:00:00"}