{"id":"https://openalex.org/W4413878415","doi":"https://doi.org/10.1186/s12880-025-01913-9","title":"CT-based deep learning radiomics model for predicting proliferative hepatocellular carcinoma: application in transarterial chemoembolization and radiofrequency ablation","display_name":"CT-based deep learning radiomics model for predicting proliferative hepatocellular carcinoma: application in transarterial chemoembolization and radiofrequency ablation","publication_year":2025,"publication_date":"2025-09-01","ids":{"openalex":"https://openalex.org/W4413878415","doi":"https://doi.org/10.1186/s12880-025-01913-9","pmid":"https://pubmed.ncbi.nlm.nih.gov/40890681"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-025-01913-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-01913-9","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01913-9","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01913-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086125027","display_name":"Hengtao Zhang","orcid":"https://orcid.org/0000-0001-6999-2907"},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hengtao Zhang","raw_affiliation_strings":["Medical School of Nankai University, Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical School of Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019029683","display_name":"Z.H. Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhaogang Zhang","raw_affiliation_strings":["Medical School of Nankai University, Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical School of Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115594328","display_name":"Kun Zhang","orcid":"https://orcid.org/0000-0002-1088-5813"},"institutions":[{"id":"https://openalex.org/I5740404","display_name":"Tianjin Medical University","ror":"https://ror.org/02mh8wx89","country_code":"CN","type":"education","lineage":["https://openalex.org/I5740404"]},{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]},{"id":"https://openalex.org/I2800200322","display_name":"Tianjin First Center Hospital","ror":"https://ror.org/02ch1zb66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800200322"]},{"id":"https://openalex.org/I4210093484","display_name":"Tianjin Nankai Hospital","ror":"https://ror.org/00hq79z10","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093484"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kun Zhang","raw_affiliation_strings":["Department of Radiology, Tianjin First Central Hospital, Tianjin Institute of Imaging Medicine, School of Medicine, Nankai University, 24 Fukang Road, Nankai District, Tianjin, 300192, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Tianjin First Central Hospital, Tianjin Institute of Imaging Medicine, School of Medicine, Nankai University, 24 Fukang Road, Nankai District, Tianjin, 300192, China","institution_ids":["https://openalex.org/I5740404","https://openalex.org/I2800200322","https://openalex.org/I4210093484","https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055579595","display_name":"Zhongsong Gao","orcid":null},"institutions":[{"id":"https://openalex.org/I4210088587","display_name":"Tianjin Third Central Hospital","ror":"https://ror.org/00911j719","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210088587"]},{"id":"https://openalex.org/I5740404","display_name":"Tianjin Medical University","ror":"https://ror.org/02mh8wx89","country_code":"CN","type":"education","lineage":["https://openalex.org/I5740404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhongsong Gao","raw_affiliation_strings":["Department of Interventional Radiology, Tianjin Third Central Hospital, Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Radiology, Tianjin Third Central Hospital, Tianjin, China","institution_ids":["https://openalex.org/I4210088587","https://openalex.org/I5740404"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069260840","display_name":"Zhiwei Shen","orcid":"https://orcid.org/0000-0003-2817-6959"},"institutions":[{"id":"https://openalex.org/I1329325741","display_name":"Philips (Finland)","ror":"https://ror.org/01g4jev56","country_code":"FI","type":"company","lineage":["https://openalex.org/I1329325741","https://openalex.org/I4210122849"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Zhiwei Shen","raw_affiliation_strings":["Philips Healthcare, The World Profit Centre, No. 16 Tianze Road, Chaoyang District, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Philips Healthcare, The World Profit Centre, No. 16 Tianze Road, Chaoyang District, Beijing, China","institution_ids":["https://openalex.org/I1329325741"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039317720","display_name":"Wen Shen","orcid":"https://orcid.org/0000-0003-2695-7890"},"institutions":[{"id":"https://openalex.org/I5740404","display_name":"Tianjin Medical University","ror":"https://ror.org/02mh8wx89","country_code":"CN","type":"education","lineage":["https://openalex.org/I5740404"]},{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]},{"id":"https://openalex.org/I4210093484","display_name":"Tianjin Nankai Hospital","ror":"https://ror.org/00hq79z10","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093484"]},{"id":"https://openalex.org/I2800200322","display_name":"Tianjin First Center Hospital","ror":"https://ror.org/02ch1zb66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800200322"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wen Shen","raw_affiliation_strings":["Department of Radiology, Tianjin First Central Hospital, Tianjin Institute of Imaging Medicine, School of Medicine, Nankai University, 24 Fukang Road, Nankai District, Tianjin, 300192, China. shen_hos@163.com","Department of Radiology, Tianjin First Central Hospital, Tianjin Institute of Imaging Medicine, School of Medicine, Nankai University, 24 Fukang Road, Nankai District, Tianjin, 300192, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Tianjin First Central Hospital, Tianjin Institute of Imaging Medicine, School of Medicine, Nankai University, 24 Fukang Road, Nankai District, Tianjin, 300192, China. shen_hos@163.com","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology, Tianjin First Central Hospital, Tianjin Institute of Imaging Medicine, School of Medicine, Nankai University, 24 Fukang Road, Nankai District, Tianjin, 300192, China","institution_ids":["https://openalex.org/I5740404","https://openalex.org/I2800200322","https://openalex.org/I4210093484","https://openalex.org/I205237279"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5086125027"],"corresponding_institution_ids":["https://openalex.org/I205237279"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":2.0142,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.87969229,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"25","issue":"1","first_page":"363","last_page":"363"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10449","display_name":"Renal cell carcinoma treatment","score":0.977400004863739,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiomics","display_name":"Radiomics","score":0.9109249711036682},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"Hepatocellular carcinoma","score":0.7831565141677856},{"id":"https://openalex.org/keywords/radiofrequency-ablation","display_name":"Radiofrequency ablation","score":0.7701377868652344},{"id":"https://openalex.org/keywords/ablation","display_name":"Ablation","score":0.6081850528717041},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.5094240307807922},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.47278520464897156},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3902463912963867},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3318135440349579},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.1733727753162384},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.11526164412498474}],"concepts":[{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.9109249711036682},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.7831565141677856},{"id":"https://openalex.org/C2777377203","wikidata":"https://www.wikidata.org/wiki/Q1809554","display_name":"Radiofrequency ablation","level":3,"score":0.7701377868652344},{"id":"https://openalex.org/C2778902805","wikidata":"https://www.wikidata.org/wiki/Q322177","display_name":"Ablation","level":2,"score":0.6081850528717041},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5094240307807922},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47278520464897156},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3902463912963867},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3318135440349579},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.1733727753162384},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11526164412498474}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1186/s12880-025-01913-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-01913-9","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01913-9","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:40890681","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40890681","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:doaj.org/article:b6b32ccb94da4516a0a1269b511578c4","is_oa":true,"landing_page_url":"https://doaj.org/article/b6b32ccb94da4516a0a1269b511578c4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 25, Iss 1, Pp 1-13 (2025)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:11213785","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12403943","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:12403943","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12403943/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Imaging","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12880-025-01913-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-01913-9","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01913-9","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G7506803716","display_name":null,"funder_award_id":"82271971","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4413878415.pdf","grobid_xml":"https://content.openalex.org/works/W4413878415.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1987124179","https://openalex.org/W2013051683","https://openalex.org/W2054211598","https://openalex.org/W2083927153","https://openalex.org/W2780918397","https://openalex.org/W2796067155","https://openalex.org/W2911605224","https://openalex.org/W2952676090","https://openalex.org/W2975603936","https://openalex.org/W2977528366","https://openalex.org/W3047998978","https://openalex.org/W3118247837","https://openalex.org/W3134553072","https://openalex.org/W3135417939","https://openalex.org/W3162740381","https://openalex.org/W3177761908","https://openalex.org/W3185427630","https://openalex.org/W3205076722","https://openalex.org/W3213277274","https://openalex.org/W4200438520","https://openalex.org/W4214920103","https://openalex.org/W4220909506","https://openalex.org/W4229061204","https://openalex.org/W4232342538","https://openalex.org/W4283582061","https://openalex.org/W4323535625","https://openalex.org/W4362640431","https://openalex.org/W4366241039","https://openalex.org/W4385666904","https://openalex.org/W4386046610","https://openalex.org/W4386247077","https://openalex.org/W4388813820","https://openalex.org/W4389399690","https://openalex.org/W4391986640","https://openalex.org/W4392509680","https://openalex.org/W4395001413","https://openalex.org/W4396227371","https://openalex.org/W4401153839","https://openalex.org/W4401846561","https://openalex.org/W4402106460","https://openalex.org/W4405323264"],"related_works":["https://openalex.org/W3000891326","https://openalex.org/W4205100762","https://openalex.org/W2559998622","https://openalex.org/W2605851261","https://openalex.org/W2734724112","https://openalex.org/W2582997534","https://openalex.org/W3009210156","https://openalex.org/W4388577230","https://openalex.org/W3029453443","https://openalex.org/W2316468655"],"abstract_inverted_index":{"Proliferative":[0],"hepatocellular":[1],"carcinoma":[2],"(HCC)":[3],"is":[4],"an":[5,91,99,196],"aggressive":[6],"tumor":[7],"with":[8,49,71,195],"varying":[9],"prognosis":[10],"depending":[11],"on":[12,34],"the":[13,153,158,204,212,222,241,244,253,260,268,272,290],"different":[14],"disease":[15],"stages":[16],"and":[17,25,41,53,68,98,123,131,142,149,172,182,216,237],"subsequent":[18],"treatment.":[19],"This":[20],"study":[21],"aims":[22],"to":[23,37,42,121,174,252],"develop":[24,122],"validate":[26,124],"a":[27,85,264],"deep":[28],"learning":[29,117],"radiomics":[30],"(DLR)":[31],"model":[32,190,282],"based":[33],"contrast-enhanced":[35,112,280],"CT":[36,113,281],"predict":[38],"proliferative":[39,125,187,287],"HCC":[40,72,126,188],"implement":[43],"risk":[44,162,231,292],"prediction":[45,127,163,189,232,285,293],"in":[46,129,168,180,203,211,221,235],"patients":[47,58,135,234,297],"treated":[48],"transarterial":[50],"chemoembolization":[51],"(TACE)":[52],"radiofrequency":[54],"ablation":[55],"(RFA).":[56],"312":[57],"(mean":[59],"age,":[60],"58":[61],"years":[62],"\u00b1":[63],"10":[64],"[SD];":[65],"261":[66],"men":[67],"51":[69],"women)":[70],"undergoing":[73,298],"surgery":[74],"at":[75],"two":[76,137],"medical":[77],"centers":[78],"were":[79,82,108,119,145],"included,":[80],"who":[81],"divided":[83,146],"into":[84,147],"training":[86,130,205],"set":[87,94,102,215,274],"(n":[88,95,103],"=":[89,96,104,257,276],"182),":[90],"internal":[92,213],"test":[93,101,132,214,224],"46)":[97],"external":[100,223],"84).":[105],"DLR":[106,154,166,186,227,291],"features":[107],"extracted":[109],"from":[110,136],"preoperative":[111],"images.":[114],"Multiple":[115],"machine":[116],"algorithms":[118],"used":[120],"models":[128],"sets.":[133,184,239],"Subsequently,":[134],"independent":[138],"new":[139],"sets":[140],"(RFA":[141],"TACE":[143,183,238,273],"sets)":[144],"high-":[148],"low-risk":[150,245,261],"groups":[151],"using":[152],"score":[155,228],"generated":[156],"by":[157],"optimal":[159],"model.":[160],"The":[161,185,226,278],"value":[164],"of":[165,198,286],"scores":[167],"recurrence-free":[169],"survival":[170],"(RFS)":[171],"time":[173],"progression":[175],"(TTP)":[176],"was":[177],"examined":[178],"separately":[179],"RFA":[181,236,242,299],"demonstrated":[191],"excellent":[192],"predictive":[193],"performance":[194],"AUC":[197],"0.906":[199],"(95%":[200,208,218],"CI":[201,209,219],"0.861\u20130.952)":[202],"set,":[206,243],"0.901":[207],"0.779\u20131.000)":[210],"0.837":[217],"0.746\u20130.928)":[220],"set.":[225],"effectively":[229],"enables":[230,283],"for":[233,271,305],"For":[240],"group":[246,255,262,270],"had":[247],"significantly":[248],"longer":[249,265],"RFS":[250],"compared":[251],"high-risk":[254,269,296],"(P":[256,275],"0.037).":[258],"Similarly,":[259],"showed":[263],"TTP":[266],"than":[267],"0.034).":[277],"DLR-based":[279],"non-invasive":[284],"HCC.":[288],"Furthermore,":[289],"helps":[294],"identify":[295],"or":[300],"TACE,":[301],"providing":[302],"prognostic":[303],"insights":[304],"personalized":[306],"management.":[307]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-05-19T08:33:51.333923","created_date":"2025-10-10T00:00:00"}