{"id":"https://openalex.org/W4410094500","doi":"https://doi.org/10.1186/s12880-025-01687-0","title":"The impact of cerebral vessels morphological alteration and white matter hyperintensities burden on the one-year risk of ischemic stroke recurrence","display_name":"The impact of cerebral vessels morphological alteration and white matter hyperintensities burden on the one-year risk of ischemic stroke recurrence","publication_year":2025,"publication_date":"2025-05-05","ids":{"openalex":"https://openalex.org/W4410094500","doi":"https://doi.org/10.1186/s12880-025-01687-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/40325356"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-025-01687-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-01687-0","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01687-0","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01687-0","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041090548","display_name":"Hao Wang","orcid":"https://orcid.org/0000-0002-5438-1211"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210101358","display_name":"Minhang District Central Hospital","ror":"https://ror.org/00p0n9a62","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210101358"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]},{"id":"https://openalex.org/I4210164150","display_name":"Shanghai Center for Brain Science and Brain-Inspired Technology","ror":"https://ror.org/0551a0y31","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210164150"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Wang","raw_affiliation_strings":["Department of Neurology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Rd, Xuhui District, Shanghai, 200032, China","Department of Radiology, Minhang Hospital, Fudan University, Shanghai, China","Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Rd, Xuhui District, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Radiology, Minhang Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210101358"]},{"raw_affiliation_string":"Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210164150"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101833938","display_name":"Guoqing Wu","orcid":null},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guoqing Wu","raw_affiliation_strings":["Department of Electronic Engineering, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electronic Engineering, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100349957","display_name":"Bei Wang","orcid":"https://orcid.org/0000-0002-9530-0385"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210164150","display_name":"Shanghai Center for Brain Science and Brain-Inspired Technology","ror":"https://ror.org/0551a0y31","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210164150"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bei Wang","raw_affiliation_strings":["Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210164150"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100414087","display_name":"Ying Liu","orcid":"https://orcid.org/0000-0001-9147-5383"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Liu","raw_affiliation_strings":["Department of Neurology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Rd, Xuhui District, Shanghai, 200032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Rd, Xuhui District, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101753256","display_name":"Lan Zheng","orcid":"https://orcid.org/0000-0003-2738-9063"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210101358","display_name":"Minhang District Central Hospital","ror":"https://ror.org/00p0n9a62","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210101358"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lan Zheng","raw_affiliation_strings":["Department of Neurology, Minhang Hospital, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Minhang Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210101358"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100351659","display_name":"He Wang","orcid":"https://orcid.org/0000-0002-2053-9439"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210101358","display_name":"Minhang District Central Hospital","ror":"https://ror.org/00p0n9a62","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210101358"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]},{"id":"https://openalex.org/I4210164150","display_name":"Shanghai Center for Brain Science and Brain-Inspired Technology","ror":"https://ror.org/0551a0y31","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210164150"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"He Wang","raw_affiliation_strings":["Department of Neurology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Rd, Xuhui District, Shanghai, 200032, China","Department of Radiology, Minhang Hospital, Fudan University, Shanghai, China","Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Rd, Xuhui District, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Radiology, Minhang Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210101358"]},{"raw_affiliation_string":"Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210164150"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073326366","display_name":"Jing Ding","orcid":"https://orcid.org/0000-0001-5135-4210"},"institutions":[{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]},{"id":"https://openalex.org/I4210146205","display_name":"Obstetrics and Gynecology Hospital of Fudan University","ror":"https://ror.org/04rhdtb47","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146205"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jing Ding","raw_affiliation_strings":["Department of Neurology, Minhang Hospital, Fudan University, Shanghai, China. ding.jing@zs-hospital.sh.cn","Department of Neurology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Rd, Xuhui District, Shanghai, 200032, China. ding.jing@zs-hospital.sh.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Minhang Hospital, Fudan University, Shanghai, China. ding.jing@zs-hospital.sh.cn","institution_ids":["https://openalex.org/I4210146205"]},{"raw_affiliation_string":"Department of Neurology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Rd, Xuhui District, Shanghai, 200032, China. ding.jing@zs-hospital.sh.cn","institution_ids":["https://openalex.org/I4210127074"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5073326366"],"corresponding_institution_ids":["https://openalex.org/I4210127074","https://openalex.org/I4210146205"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":{"value":2890,"currency":"USD","value_usd":2890},"fwci":0.7445,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.69579635,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"25","issue":"1","first_page":"150","last_page":"150"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.7829999923706055,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.7829999923706055,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.10750000178813934,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.04439999908208847,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperintensity","display_name":"Hyperintensity","score":0.8579122424125671},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"Ischemic stroke","score":0.6725505590438843},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.598468005657196},{"id":"https://openalex.org/keywords/white-matter","display_name":"White matter","score":0.5368244051933289},{"id":"https://openalex.org/keywords/stroke","display_name":"Stroke (engine)","score":0.49413469433784485},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.4323524236679077},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.3720608353614807},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.32959866523742676},{"id":"https://openalex.org/keywords/ischemia","display_name":"Ischemia","score":0.21671056747436523}],"concepts":[{"id":"https://openalex.org/C146638467","wikidata":"https://www.wikidata.org/wiki/Q10529587","display_name":"Hyperintensity","level":3,"score":0.8579122424125671},{"id":"https://openalex.org/C3020199598","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischemic stroke","level":3,"score":0.6725505590438843},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.598468005657196},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.5368244051933289},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.49413469433784485},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.4323524236679077},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3720608353614807},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.32959866523742676},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.21671056747436523},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000072226","descriptor_name":"Computed Tomography Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072226","descriptor_name":"Computed Tomography Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072226","descriptor_name":"Computed Tomography Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072226","descriptor_name":"Computed Tomography Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000083242","descriptor_name":"Ischemic Stroke","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000083242","descriptor_name":"Ischemic Stroke","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000083242","descriptor_name":"Ischemic Stroke","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000083242","descriptor_name":"Ischemic Stroke","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000083242","descriptor_name":"Ischemic Stroke","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000083242","descriptor_name":"Ischemic Stroke","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000083242","descriptor_name":"Ischemic Stroke","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000083242","descriptor_name":"Ischemic Stroke","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12880-025-01687-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-01687-0","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01687-0","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:40325356","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40325356","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:doaj.org/article:6fbb5188afc242afaa80cf8a408e41bb","is_oa":true,"landing_page_url":"https://doaj.org/article/6fbb5188afc242afaa80cf8a408e41bb","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 25, Iss 1, Pp 1-13 (2025)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:10866127","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12054279","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12880-025-01687-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-01687-0","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01687-0","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5899999737739563,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321851","display_name":"Fudan University","ror":"https://ror.org/013q1eq08"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410094500.pdf","grobid_xml":"https://content.openalex.org/works/W4410094500.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W2054956838","https://openalex.org/W2097457623","https://openalex.org/W2130766313","https://openalex.org/W2157868610","https://openalex.org/W2158742097","https://openalex.org/W2334170987","https://openalex.org/W2461805626","https://openalex.org/W2512751957","https://openalex.org/W2776531405","https://openalex.org/W2789628513","https://openalex.org/W2818723673","https://openalex.org/W2894685768","https://openalex.org/W2913869981","https://openalex.org/W2924761079","https://openalex.org/W2934542510","https://openalex.org/W2958464485","https://openalex.org/W3000103051","https://openalex.org/W3014974815","https://openalex.org/W3042131576","https://openalex.org/W3112701542","https://openalex.org/W3118806490","https://openalex.org/W3157892075","https://openalex.org/W3174840106","https://openalex.org/W3175734142","https://openalex.org/W3209828359","https://openalex.org/W3213988304","https://openalex.org/W3216729025","https://openalex.org/W4210440929","https://openalex.org/W4226028310","https://openalex.org/W4226042993","https://openalex.org/W4226225360","https://openalex.org/W4283766937","https://openalex.org/W4377939760","https://openalex.org/W4377940349","https://openalex.org/W4390426154","https://openalex.org/W4392155315","https://openalex.org/W4393864528","https://openalex.org/W4396812929"],"related_works":["https://openalex.org/W2090103820","https://openalex.org/W3206072240","https://openalex.org/W2021468470","https://openalex.org/W2106430568","https://openalex.org/W2082419882","https://openalex.org/W2117421758","https://openalex.org/W1991894501","https://openalex.org/W2107764488","https://openalex.org/W2067113209","https://openalex.org/W3092209499"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"assess":[2],"the":[3,15,113,128,139,229,244],"associations":[4,137],"between":[5,138],"cerebral":[6,151,195,216,239],"vessels":[7,61,196,217,240],"morphological":[8,62,218,241],"features,":[9],"white":[10],"matter":[11],"hyperintensities":[12],"(WMHs),":[13],"and":[14,47,73,79,148,153,203,220],"one-year":[16,114,161,230],"risk":[17,115,162,231],"of":[18,25,75,116,121,141,150,156,163,215,232,238],"ischemic":[19,31,165,233],"stroke":[20,32,117,166,234],"recurrence.":[21,118,235],"METHODS:":[22],"A":[23],"total":[24],"677":[26],"patients":[27],"diagnosed":[28],"with":[29,158],"acute":[30],"from":[33],"January":[34],"2018":[35],"to":[36,111],"April":[37],"2021":[38],"were":[39,56,77,104],"consecutively":[40],"enrolled.":[41],"Head":[42],"computed":[43],"tomography":[44],"angiography":[45],"(CTA)":[46],"magnetic":[48],"resonance":[49],"imaging":[50],"including":[51],"fluid-attenuated":[52],"inversion":[53],"recovery":[54],"(FLAIR),":[55],"obtained":[57],"on":[58,94,187],"admission.":[59],"Cerebral":[60],"features":[63,219,242],"such":[64],"as":[65],"volume,":[66],"length,":[67],"radius,":[68],"density,":[69],"tortuosity,":[70],"branch":[71],"complexity,":[72],"degree":[74],"stenosis":[76],"extracted":[78],"calculated":[80],"using":[81,106],"CTA":[82],"data.":[83],"Additionally,":[84],"automated":[85],"segmentation":[86],"was":[87,124],"employed":[88],"for":[89,227],"delineating":[90],"WMHs":[91,204,221],"lesions":[92],"based":[93,185],"FLAIR":[95],"images.":[96],"By":[97],"incorporating":[98],"clinical":[99,188],"characteristics,":[100],"six":[101],"predictive":[102,245],"models":[103,123,184],"developed":[105],"Cox":[107],"proportional":[108],"hazards":[109],"analysis":[110],"estimate":[112],"The":[119,133,171,212,236],"performance":[120],"these":[122],"evaluated":[125],"by":[126],"comparing":[127],"concordance":[129],"index":[130],"(C-index).":[131],"RESULTS:":[132],"study":[134],"found":[135],"significant":[136],"lack":[140],"antiplatelet":[142],"therapy":[143],"at":[144],"discharge,":[145],"reduced":[146],"length":[147],"branching":[149],"vessels,":[152],"increased":[154],"burden":[155,205],"WMHs,":[157],"a":[159,223],"higher":[160],"recurrent":[164],"(all":[167],"P":[168],"<":[169],"0.05).":[170],"integrated":[172],"model":[173],"demonstrated":[174],"superior":[175],"prognostic":[176],"capability":[177],"(C-index:":[178,190,198,206],"0.750;":[179],"95%":[180,192,200,208],"CI:":[181,193,201,209],"0.684-0.817),":[182],"outperforming":[183],"solely":[186],"characteristics":[189],"0.636;":[191],"0.555-0.717),":[194],"morphology":[197],"0.601;":[199],"0.526-0.676),":[202],"0.680;":[207],"0.603-0.757).":[210],"CONCLUSION:":[211],"quantitative":[213],"assessment":[214],"provides":[222],"promising":[224],"neuroimaging":[225],"tool":[226],"estimating":[228],"incorporation":[237],"enhances":[243],"accuracy.":[246]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-07-29T09:40:50.615796","created_date":"2025-10-10T00:00:00"}