{"id":"https://openalex.org/W4409700424","doi":"https://doi.org/10.1186/s12880-025-01674-5","title":"Dual contrast-enhanced ultrasound for diagnosing pathologic nipple discharge associated with papillary lesions","display_name":"Dual contrast-enhanced ultrasound for diagnosing pathologic nipple discharge associated with papillary lesions","publication_year":2025,"publication_date":"2025-04-23","ids":{"openalex":"https://openalex.org/W4409700424","doi":"https://doi.org/10.1186/s12880-025-01674-5","pmid":"https://pubmed.ncbi.nlm.nih.gov/40269744"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-025-01674-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-01674-5","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01674-5","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01674-5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103278764","display_name":"Yanchun Zhao","orcid":"https://orcid.org/0000-0001-5253-0554"},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]},{"id":"https://openalex.org/I4210134617","display_name":"Second Affiliated Hospital of Fujian Medical University","ror":"https://ror.org/03wnxd135","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134617"]},{"id":"https://openalex.org/I4210143087","display_name":"Fujian Provincial Hospital","ror":"https://ror.org/045wzwx52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143087"]},{"id":"https://openalex.org/I80947539","display_name":"Fuzhou University","ror":"https://ror.org/011xvna82","country_code":"CN","type":"education","lineage":["https://openalex.org/I80947539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanchun Zhao","raw_affiliation_strings":["Department of Ultrasonography, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China","Department of Ultrasound, The Second Affiliated Hospital of Fujian Medical University, Licheng District, Quanzhou, Fujian, 362000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ultrasonography, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China","institution_ids":["https://openalex.org/I4210143087","https://openalex.org/I80947539"]},{"raw_affiliation_string":"Department of Ultrasound, The Second Affiliated Hospital of Fujian Medical University, Licheng District, Quanzhou, Fujian, 362000, China","institution_ids":["https://openalex.org/I129708740","https://openalex.org/I4210134617"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109496044","display_name":"Songsong Wu","orcid":"https://orcid.org/0009-0005-1973-3604"},"institutions":[{"id":"https://openalex.org/I4210143087","display_name":"Fujian Provincial Hospital","ror":"https://ror.org/045wzwx52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143087"]},{"id":"https://openalex.org/I80947539","display_name":"Fuzhou University","ror":"https://ror.org/011xvna82","country_code":"CN","type":"education","lineage":["https://openalex.org/I80947539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Songsong Wu","raw_affiliation_strings":["Department of Ultrasonography, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ultrasonography, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China","institution_ids":["https://openalex.org/I4210143087","https://openalex.org/I80947539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022390320","display_name":"Zhongtao Bao","orcid":"https://orcid.org/0000-0003-2536-6714"},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]},{"id":"https://openalex.org/I4210121761","display_name":"First Affiliated Hospital of Fujian Medical University","ror":"https://ror.org/030e09f60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhongtao Bao","raw_affiliation_strings":["Department of Ultrasound, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ultrasound, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China","institution_ids":["https://openalex.org/I129708740","https://openalex.org/I4210121761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053662503","display_name":"Yu\u2010Cheng Lin","orcid":"https://orcid.org/0000-0003-2264-4491"},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yucheng Lin","raw_affiliation_strings":["Department of Medical Ultrasonics, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Ultrasonics, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, China","institution_ids":["https://openalex.org/I129708740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101903448","display_name":"Ziwei Xu","orcid":"https://orcid.org/0000-0003-3945-7000"},"institutions":[{"id":"https://openalex.org/I4210143087","display_name":"Fujian Provincial Hospital","ror":"https://ror.org/045wzwx52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143087"]},{"id":"https://openalex.org/I80947539","display_name":"Fuzhou University","ror":"https://ror.org/011xvna82","country_code":"CN","type":"education","lineage":["https://openalex.org/I80947539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ziwei Xu","raw_affiliation_strings":["Department of Ultrasonography, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ultrasonography, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China","institution_ids":["https://openalex.org/I4210143087","https://openalex.org/I80947539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101645274","display_name":"Xing Chen","orcid":"https://orcid.org/0000-0002-4014-7037"},"institutions":[{"id":"https://openalex.org/I4210143087","display_name":"Fujian Provincial Hospital","ror":"https://ror.org/045wzwx52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143087"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xing Chen","raw_affiliation_strings":["Department of Basic Surgery, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Basic Surgery, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China","institution_ids":["https://openalex.org/I4210143087"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017198222","display_name":"Lingpeng Tang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210143087","display_name":"Fujian Provincial Hospital","ror":"https://ror.org/045wzwx52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143087"]},{"id":"https://openalex.org/I80947539","display_name":"Fuzhou University","ror":"https://ror.org/011xvna82","country_code":"CN","type":"education","lineage":["https://openalex.org/I80947539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lingpeng Tang","raw_affiliation_strings":["Department of Ultrasonography, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ultrasonography, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China","institution_ids":["https://openalex.org/I4210143087","https://openalex.org/I80947539"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084570636","display_name":"Guorong Lyu","orcid":"https://orcid.org/0000-0003-3123-1138"},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]},{"id":"https://openalex.org/I4210134617","display_name":"Second Affiliated Hospital of Fujian Medical University","ror":"https://ror.org/03wnxd135","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134617"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guorong Lyu","raw_affiliation_strings":["Department of Ultrasound, The Second Affiliated Hospital of Fujian Medical University, Licheng District, Quanzhou, Fujian, 362000, China. lgr_feus@sina.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ultrasound, The Second Affiliated Hospital of Fujian Medical University, Licheng District, Quanzhou, Fujian, 362000, China. lgr_feus@sina.com","institution_ids":["https://openalex.org/I129708740","https://openalex.org/I4210134617"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":{"value":2890,"currency":"USD","value_usd":2890},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10507171,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"25","issue":"1","first_page":"132","last_page":"132"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11258","display_name":"Breast Implant and Reconstruction","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11868","display_name":"Cancer and Skin Lesions","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ultrasound","display_name":"Ultrasound","score":0.6382695436477661},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5713210105895996},{"id":"https://openalex.org/keywords/contrast-enhanced-ultrasound","display_name":"Contrast-enhanced ultrasound","score":0.5670197010040283},{"id":"https://openalex.org/keywords/nipple-discharge","display_name":"Nipple discharge","score":0.5463970899581909},{"id":"https://openalex.org/keywords/contrast","display_name":"Contrast (vision)","score":0.5168581604957581},{"id":"https://openalex.org/keywords/contrast-enhancement","display_name":"Contrast enhancement","score":0.49609503149986267},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.49595746397972107},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.35622817277908325},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.2811029553413391},{"id":"https://openalex.org/keywords/mammography","display_name":"Mammography","score":0.1886257529258728},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.1288299858570099},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.06783118844032288},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.054945409297943115}],"concepts":[{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.6382695436477661},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5713210105895996},{"id":"https://openalex.org/C2779585989","wikidata":"https://www.wikidata.org/wiki/Q500458","display_name":"Contrast-enhanced ultrasound","level":3,"score":0.5670197010040283},{"id":"https://openalex.org/C2780898380","wikidata":"https://www.wikidata.org/wiki/Q3543799","display_name":"Nipple discharge","level":5,"score":0.5463970899581909},{"id":"https://openalex.org/C2776502983","wikidata":"https://www.wikidata.org/wiki/Q690182","display_name":"Contrast (vision)","level":2,"score":0.5168581604957581},{"id":"https://openalex.org/C3018181011","wikidata":"https://www.wikidata.org/wiki/Q6849688","display_name":"Contrast enhancement","level":3,"score":0.49609503149986267},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.49595746397972107},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.35622817277908325},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2811029553413391},{"id":"https://openalex.org/C2780472235","wikidata":"https://www.wikidata.org/wiki/Q324634","display_name":"Mammography","level":4,"score":0.1886257529258728},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1288299858570099},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.06783118844032288},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.054945409297943115},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000071936","descriptor_name":"Nipple Discharge","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000071936","descriptor_name":"Nipple Discharge","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000071936","descriptor_name":"Nipple Discharge","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000071936","descriptor_name":"Nipple Discharge","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000071936","descriptor_name":"Nipple Discharge","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000071936","descriptor_name":"Nipple Discharge","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009558","descriptor_name":"Nipples","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016217","descriptor_name":"Ultrasonography, Mammary","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016217","descriptor_name":"Ultrasonography, Mammary","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016217","descriptor_name":"Ultrasonography, Mammary","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016217","descriptor_name":"Ultrasonography, Mammary","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016217","descriptor_name":"Ultrasonography, Mammary","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016217","descriptor_name":"Ultrasonography, Mammary","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12880-025-01674-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-01674-5","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01674-5","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:40269744","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40269744","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:3ca3a120cdef478690fa1aa6e86e16ad","is_oa":true,"landing_page_url":"https://doaj.org/article/3ca3a120cdef478690fa1aa6e86e16ad","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 25, Iss 1, Pp 1-11 (2025)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:10830334","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12020028","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12880-025-01674-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-025-01674-5","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01674-5","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G5295065897","display_name":null,"funder_award_id":"No. 2020J011090","funder_id":"https://openalex.org/F4320321878","funder_display_name":"Natural Science Foundation of Fujian Province"}],"funders":[{"id":"https://openalex.org/F4320321878","display_name":"Natural Science Foundation of Fujian Province","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409700424.pdf","grobid_xml":"https://content.openalex.org/works/W4409700424.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1818735246","https://openalex.org/W2065727458","https://openalex.org/W2473657539","https://openalex.org/W2524349664","https://openalex.org/W2583479711","https://openalex.org/W2593632596","https://openalex.org/W2770215686","https://openalex.org/W2793887421","https://openalex.org/W2963305103","https://openalex.org/W2969446237","https://openalex.org/W2995217159","https://openalex.org/W3002714376","https://openalex.org/W3004320252","https://openalex.org/W3046945405","https://openalex.org/W3111391509","https://openalex.org/W3112901637","https://openalex.org/W3116042030","https://openalex.org/W3153042027","https://openalex.org/W3154925622","https://openalex.org/W3164343879","https://openalex.org/W4213328676","https://openalex.org/W4283519921","https://openalex.org/W4293424878","https://openalex.org/W4294081033","https://openalex.org/W4310065432","https://openalex.org/W4322500602","https://openalex.org/W4323921111","https://openalex.org/W4388461697"],"related_works":["https://openalex.org/W2133801956","https://openalex.org/W2098128511","https://openalex.org/W3175806596","https://openalex.org/W2361931043","https://openalex.org/W4239222040","https://openalex.org/W2388437948","https://openalex.org/W2366928440","https://openalex.org/W2163751115","https://openalex.org/W2914841929","https://openalex.org/W2375603474"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,101,166,208],"goal":[2],"of":[3,12,51,89,119,142,176,244],"this":[4],"research":[5],"study":[6,31,102],"is":[7,224],"to":[8,66,93,112,148],"determine":[9],"the":[10,77,86,177,192,195,211,242],"efficacy":[11,88],"dual":[13,45,90,151],"contrast-enhanced":[14,46,91,152,222],"ultrasound":[15],"(US)":[16],"in":[17,96,108,134,144,157,231],"evaluating":[18],"ductal":[19,55,190],"papillary":[20,56,98,132,145,161,182,216,238],"lesions":[21,57,133,162,217],"associated":[22,180],"with":[23,131,137,181],"pathological":[24,71,232],"nipple":[25,233],"discharge.":[26],"METHODS:":[27],"A":[28],"prospective":[29],"multicenter":[30],"was":[32,154,218],"conducted":[33],"between":[34,194],"January":[35],"2020":[36],"and":[37,48,63,73,159,197,199,236,240],"December":[38],"2022.":[39],"All":[40],"participants":[41,106],"were":[42,58,122],"examined":[43],"using":[44,60],"US":[47,61,92,95,153,223],"had":[49],"re-adjustment":[50],"BI-RADS":[52,168,245],"classification.":[53,246],"Genuine":[54],"identified":[59],"features":[62],"subsequently":[64],"subjected":[65],"biopsy":[67],"or":[68],"excision.":[69],"Using":[70],"results":[72],"clinical":[74],"follow-up":[75],"as":[76,80],"reference":[78],"standard":[79,82],"a":[81,172],"reference,":[83],"we":[84],"compared":[85],"diagnostic":[87],"conventional":[94,149],"detecting":[97,160,214,235],"lesions.":[99,146,183],"RESULTS:":[100],"included":[103],"102":[104],"female":[105],"ranging":[107],"age":[109],"from":[110],"29":[111],"80":[113],"years":[114],"(average":[115],"47.6":[116],"\u00b1":[117],"9.4),":[118],"whom":[120],"87":[121],"retained":[123],"for":[124,171,206,213],"analysis.":[125],"We":[126],"precisely":[127,227],"localized":[128],"discharging":[129],"ducts":[130,230],"85":[135],"patients,":[136],"68":[138],"showing":[139],"varying":[140],"degrees":[141],"enhancement":[143],"Compared":[147],"US,":[150],"more":[155,173],"accurate":[156],"locating":[158,228],"(P":[163],"<":[164],"0.001).":[165],"optimized":[167],"classification":[169],"allowed":[170],"informed":[174],"prediction":[175],"malignancy":[178],"risk":[179,204],"Multivariate":[184],"logistic":[185],"regression":[186],"analysis":[187],"revealed":[188],"that":[189],"continuity,":[191],"boundary":[193],"nodule":[196],"duct,":[198],"peak":[200],"intensity":[201],"are":[202],"independent":[203],"factors":[205],"malignancy.":[207],"area":[209],"under":[210],"curve":[212],"malignant":[215],"0.937.":[219],"CONCLUSIONS:":[220],"Dual":[221],"effective":[225],"at":[226],"lactiferous":[229],"discharge,":[234],"differentiating":[237],"lesions,":[239],"improving":[241],"accuracy":[243]},"counts_by_year":[],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}