{"id":"https://openalex.org/W4396561764","doi":"https://doi.org/10.1186/s12880-024-01281-w","title":"Automated region growing-based segmentation for trabecular bone structure in fresh-frozen human wrist specimens","display_name":"Automated region growing-based segmentation for trabecular bone structure in fresh-frozen human wrist specimens","publication_year":2024,"publication_date":"2024-05-01","ids":{"openalex":"https://openalex.org/W4396561764","doi":"https://doi.org/10.1186/s12880-024-01281-w","pmid":"https://pubmed.ncbi.nlm.nih.gov/38693510"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-024-01281-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01281-w","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01281-w","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01281-w","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059047241","display_name":"Eva Klintstr\u00f6m","orcid":"https://orcid.org/0000-0003-0884-899X"},"institutions":[{"id":"https://openalex.org/I102134673","display_name":"Link\u00f6ping University","ror":"https://ror.org/05ynxx418","country_code":"SE","type":"education","lineage":["https://openalex.org/I102134673"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Eva Klintstr\u00f6m","raw_affiliation_strings":["Center for Medical Image Science and Visualization (CMIV), Link\u00f6ping University, Link\u00f6ping, SE-58185, Sweden. eva.klintstrom@liu.se","Department of Radiology and Department of Health, Medicine and Caring Sciences, Link\u00f6ping University, Link\u00f6ping, SE-58185, Sweden. eva.klintstrom@liu.se","Center for Medical Image Science and Visualization (CMIV), Link\u00f6ping University, Link\u00f6ping, SE-58185, Sweden"],"affiliations":[{"raw_affiliation_string":"Center for Medical Image Science and Visualization (CMIV), Link\u00f6ping University, Link\u00f6ping, SE-58185, Sweden. eva.klintstrom@liu.se","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology and Department of Health, Medicine and Caring Sciences, Link\u00f6ping University, Link\u00f6ping, SE-58185, Sweden. eva.klintstrom@liu.se","institution_ids":[]},{"raw_affiliation_string":"Center for Medical Image Science and Visualization (CMIV), Link\u00f6ping University, Link\u00f6ping, SE-58185, Sweden","institution_ids":["https://openalex.org/I102134673"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091045700","display_name":"Benjamin Klintstr\u00f6m","orcid":"https://orcid.org/0000-0002-6948-1784"},"institutions":[{"id":"https://openalex.org/I86987016","display_name":"KTH Royal Institute of Technology","ror":"https://ror.org/026vcq606","country_code":"SE","type":"education","lineage":["https://openalex.org/I86987016"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Benjamin Klintstr\u00f6m","raw_affiliation_strings":["Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, H\u00e4lsov\u00e4gen 11C, Huddinge, SE-14157, Sweden"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, H\u00e4lsov\u00e4gen 11C, Huddinge, SE-14157, Sweden","institution_ids":["https://openalex.org/I86987016"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084226420","display_name":"\u00d6rjan Smedby","orcid":"https://orcid.org/0000-0002-7750-1917"},"institutions":[{"id":"https://openalex.org/I86987016","display_name":"KTH Royal Institute of Technology","ror":"https://ror.org/026vcq606","country_code":"SE","type":"education","lineage":["https://openalex.org/I86987016"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"\u00d6rjan Smedby","raw_affiliation_strings":["Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, H\u00e4lsov\u00e4gen 11C, Huddinge, SE-14157, Sweden"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, H\u00e4lsov\u00e4gen 11C, Huddinge, SE-14157, Sweden","institution_ids":["https://openalex.org/I86987016"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035563653","display_name":"Rodrigo Moreno","orcid":"https://orcid.org/0000-0001-5765-2964"},"institutions":[{"id":"https://openalex.org/I86987016","display_name":"KTH Royal Institute of Technology","ror":"https://ror.org/026vcq606","country_code":"SE","type":"education","lineage":["https://openalex.org/I86987016"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Rodrigo Moreno","raw_affiliation_strings":["Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, H\u00e4lsov\u00e4gen 11C, Huddinge, SE-14157, Sweden"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, H\u00e4lsov\u00e4gen 11C, Huddinge, SE-14157, Sweden","institution_ids":["https://openalex.org/I86987016"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5059047241"],"corresponding_institution_ids":["https://openalex.org/I102134673"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.4671,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.57625878,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"24","issue":"1","first_page":"101","last_page":"101"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6595929861068726},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6063529849052429},{"id":"https://openalex.org/keywords/wrist","display_name":"Wrist","score":0.5783681869506836},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4330439567565918},{"id":"https://openalex.org/keywords/trabecular-bone","display_name":"Trabecular bone","score":0.4275127351284027},{"id":"https://openalex.org/keywords/region-growing","display_name":"Region growing","score":0.4252711832523346},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.39831024408340454},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.37985026836395264},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.32022395730018616},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.31203150749206543},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.25080347061157227},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.11168679594993591},{"id":"https://openalex.org/keywords/scale-space-segmentation","display_name":"Scale-space segmentation","score":0.08826237916946411},{"id":"https://openalex.org/keywords/osteoporosis","display_name":"Osteoporosis","score":0.06942149996757507}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6595929861068726},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6063529849052429},{"id":"https://openalex.org/C2778216619","wikidata":"https://www.wikidata.org/wiki/Q185706","display_name":"Wrist","level":2,"score":0.5783681869506836},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4330439567565918},{"id":"https://openalex.org/C3018268312","wikidata":"https://www.wikidata.org/wiki/Q2671642","display_name":"Trabecular bone","level":3,"score":0.4275127351284027},{"id":"https://openalex.org/C206824153","wikidata":"https://www.wikidata.org/wiki/Q1169834","display_name":"Region growing","level":5,"score":0.4252711832523346},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.39831024408340454},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.37985026836395264},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.32022395730018616},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.31203150749206543},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25080347061157227},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11168679594993591},{"id":"https://openalex.org/C65885262","wikidata":"https://www.wikidata.org/wiki/Q7429708","display_name":"Scale-space segmentation","level":4,"score":0.08826237916946411},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.06942149996757507}],"mesh":[{"descriptor_ui":"D000071556","descriptor_name":"Cancellous Bone","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000071556","descriptor_name":"Cancellous Bone","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000071556","descriptor_name":"Cancellous Bone","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000071556","descriptor_name":"Cancellous Bone","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014953","descriptor_name":"Wrist","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D014953","descriptor_name":"Wrist","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D014953","descriptor_name":"Wrist","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D014953","descriptor_name":"Wrist","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D055114","descriptor_name":"X-Ray Microtomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055114","descriptor_name":"X-Ray Microtomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055114","descriptor_name":"X-Ray Microtomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055114","descriptor_name":"X-Ray Microtomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12880-024-01281-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01281-w","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01281-w","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:38693510","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38693510","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11061919","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11061919","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11061919/pdf/12880_2024_Article_1281.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Imaging","raw_type":"Text"},{"id":"pmh:oai:DiVA.org:liu-203763","is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-203763","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:doaj.org/article:baf34ddfdfb649de9787d159f9324f28","is_oa":true,"landing_page_url":"https://doaj.org/article/baf34ddfdfb649de9787d159f9324f28","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 24, Iss 1, Pp 1-10 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12880-024-01281-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01281-w","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01281-w","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G419370762","display_name":null,"funder_award_id":"ALF Grants R\u00d6-936170","funder_id":"https://openalex.org/F4320316772","funder_display_name":"Region \u00d6sterg\u00f6tland"},{"id":"https://openalex.org/G6509580433","display_name":null,"funder_award_id":"Switzerland","funder_id":"https://openalex.org/F4320310992","funder_display_name":"University of Bern"}],"funders":[{"id":"https://openalex.org/F4320310992","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05"},{"id":"https://openalex.org/F4320316772","display_name":"Region \u00d6sterg\u00f6tland","ror":null},{"id":"https://openalex.org/F4320322225","display_name":"Link\u00f6pings Universitet","ror":"https://ror.org/05ynxx418"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4396561764.pdf"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1815367426","https://openalex.org/W1964983194","https://openalex.org/W1966742279","https://openalex.org/W1975535182","https://openalex.org/W2020001995","https://openalex.org/W2047018489","https://openalex.org/W2066749771","https://openalex.org/W2071091901","https://openalex.org/W2104048619","https://openalex.org/W2105368463","https://openalex.org/W2133059825","https://openalex.org/W2136887207","https://openalex.org/W2510862730","https://openalex.org/W2571094973","https://openalex.org/W2573400185","https://openalex.org/W2808662086","https://openalex.org/W3021504553","https://openalex.org/W3092363512","https://openalex.org/W3093679250","https://openalex.org/W3121813218","https://openalex.org/W3125598573","https://openalex.org/W4280489787","https://openalex.org/W4288176278"],"related_works":["https://openalex.org/W2062965168","https://openalex.org/W2157348843","https://openalex.org/W1522196789","https://openalex.org/W2382738934","https://openalex.org/W4281943322","https://openalex.org/W2394279717","https://openalex.org/W2904485911","https://openalex.org/W2122457697","https://openalex.org/W1972171786","https://openalex.org/W2364503923"],"abstract_inverted_index":{"Bone":[0],"strength":[1],"depends":[2],"on":[3,14,46],"both":[4],"mineral":[5],"content":[6],"and":[7,84,126,154,180,191,215],"bone":[8,12,44,87,157,219,241],"structure.":[9],"Measurements":[10],"of":[11,49,74,82,93,225,237,239],"microstructure":[13],"specimens":[15,51,229],"can":[16],"be":[17,115,211,246],"performed":[18,26],"by":[19,27],"micro-CT.":[20],"In":[21,36],"vivo":[22],"measurements":[23],"are":[24],"reliably":[25],"high-resolution":[28],"peripheral":[29],"computed":[30],"tomography":[31],"(HR-pQCT)":[32],"using":[33,60,230],"dedicated":[34],"software.":[35],"previous":[37],"studies":[38],"from":[39,52,89,99,131,144,163,200,221],"our":[40],"research":[41],"group,":[42],"trabecular":[43,86,152,218],"properties":[45],"CT":[47,55,91,223],"data":[48,92,121,224,232],"defatted":[50],"many":[53],"different":[54],"devices":[56],"have":[57],"been":[58],"analyzed":[59],"an":[61,207],"Automated":[62],"Region":[63],"Growing":[64],"(ARG)":[65],"algorithm-based":[66],"code,":[67],"showing":[68],"strong":[69],"correlations":[70,161,188],"to":[71,78,139,146,165,171],"micro-CT.The":[72],"aim":[73],"the":[75,80,109,175,183,195,240],"study":[76,204],"was":[77,101,107,168],"validate":[79],"possibility":[81],"segmenting":[83,214],"measuring":[85,216],"structure":[88,220,242],"clinical":[90,222],"fresh-frozen":[94,133,226],"human":[95,134,227],"wrist":[96,228],"specimens.":[97],"Data":[98],"micro-CT":[100,140,231],"used":[102,116,212],"as":[103,198,233],"reference.":[104,234],"The":[105,156],"hypothesis":[106],"that":[108,206],"ARG-based":[110,208],"in-house":[111],"built":[112],"software":[113,209],"could":[114,210],"for":[117,148,213],"such":[118],"measurements.HR-pQCT":[119],"image":[120],"at":[122,174,189],"two":[123],"resolutions":[124],"(61":[125],"82":[127],"\u00b5m":[128],"isotropic":[129],"voxels)":[130],"23":[132],"forearms":[135],"were":[136,141,182],"analyzed.":[137],"Correlations":[138],"strong,":[142],"varying":[143,162],"0.72":[145],"0.99":[147],"all":[149],"parameters":[150,186,243],"except":[151],"termini":[153],"nodes.":[155],"volume":[158],"fraction":[159],"had":[160],"0.95":[164],"0.98":[166],"but":[167],"overestimated":[169],"compared":[170],"micro-CT,":[172],"especially":[173],"lower":[176],"resolution.":[177],"Trabecular":[178],"separation":[179],"spacing":[181],"most":[184],"stable":[185],"with":[187],"0.80-0.97":[190],"mean":[192],"values":[193],"in":[194,202],"same":[196],"range":[197],"micro-CT.Results":[199],"this":[201],"vitro":[203],"show":[205],"3D":[217],"Over-and":[235],"underestimation":[236],"several":[238],"must":[244],"however":[245],"taken":[247],"into":[248],"account.":[249]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}