{"id":"https://openalex.org/W4393277909","doi":"https://doi.org/10.1186/s12880-024-01256-x","title":"The use of individual-based FDG-PET volume of interest in predicting conversion from mild cognitive impairment to dementia","display_name":"The use of individual-based FDG-PET volume of interest in predicting conversion from mild cognitive impairment to dementia","publication_year":2024,"publication_date":"2024-03-28","ids":{"openalex":"https://openalex.org/W4393277909","doi":"https://doi.org/10.1186/s12880-024-01256-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/38549082"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-024-01256-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01256-x","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01256-x","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01256-x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108055379","display_name":"Shu\u2010Hua Huang","orcid":"https://orcid.org/0000-0001-6542-5315"},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Shu-Hua Huang","raw_affiliation_strings":["Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I4210093821","https://openalex.org/I173093425"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066299618","display_name":"Wen-Chiu Hsiao","orcid":"https://orcid.org/0000-0001-5579-2488"},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Wen-Chiu Hsiao","raw_affiliation_strings":["Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan","institution_ids":["https://openalex.org/I4210093821","https://openalex.org/I173093425"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101656764","display_name":"Hsin\u2010I Chang","orcid":"https://orcid.org/0009-0007-2390-6883"},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hsin-I Chang","raw_affiliation_strings":["Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan","institution_ids":["https://openalex.org/I4210093821","https://openalex.org/I173093425"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067738548","display_name":"Mi-Chia Ma","orcid":"https://orcid.org/0000-0003-1949-3004"},"institutions":[{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Mi-Chia Ma","raw_affiliation_strings":["Department of Statistics, National Cheng Kung University, Tainan City, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, National Cheng Kung University, Tainan City, Taiwan","institution_ids":["https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101453486","display_name":"Shih\u2010Wei Hsu","orcid":"https://orcid.org/0000-0002-3564-1524"},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Shih-Wei Hsu","raw_affiliation_strings":["Department of Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I4210093821","https://openalex.org/I173093425"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062303723","display_name":"Chen\u2010Chang Lee","orcid":"https://orcid.org/0000-0002-8677-9806"},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chen-Chang Lee","raw_affiliation_strings":["Department of Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I4210093821","https://openalex.org/I173093425"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100767118","display_name":"Hongjie Chen","orcid":"https://orcid.org/0000-0002-6438-108X"},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hong-Jie Chen","raw_affiliation_strings":["Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I4210093821","https://openalex.org/I173093425"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037290375","display_name":"Ching-Heng Lin","orcid":"https://orcid.org/0000-0002-8042-5484"},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I3020100970","display_name":"Chang Gung Memorial Hospital","ror":"https://ror.org/02verss31","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I3020100970"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Ching-Heng Lin","raw_affiliation_strings":["Bachelor Program in Artificial Intelligence, Chang Gung University, Taoyuan, Taiwan","Center for Artificial Intelligence in Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bachelor Program in Artificial Intelligence, Chang Gung University, Taoyuan, Taiwan","institution_ids":["https://openalex.org/I173093425"]},{"raw_affiliation_string":"Center for Artificial Intelligence in Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan","institution_ids":["https://openalex.org/I3020100970"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101873260","display_name":"Chi\u2010Wei Huang","orcid":"https://orcid.org/0000-0002-2868-3961"},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chi-Wei Huang","raw_affiliation_strings":["Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan. justin1124@cloud.cgmh.org.tw","Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan. justin1124@cloud.cgmh.org.tw","institution_ids":["https://openalex.org/I4210093821"]},{"raw_affiliation_string":"Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan","institution_ids":["https://openalex.org/I4210093821","https://openalex.org/I173093425"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101641245","display_name":"Chiung\u2010Chih Chang","orcid":"https://orcid.org/0000-0002-6721-2556"},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chiung-Chih Chang","raw_affiliation_strings":["Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan. neur099@cgmh.org.tw","Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan. neur099@cgmh.org.tw","institution_ids":["https://openalex.org/I4210093821"]},{"raw_affiliation_string":"Department of Neurology, Cognition and Aging Center, Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiw, Taiwan","institution_ids":["https://openalex.org/I4210093821","https://openalex.org/I173093425"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5108055379"],"corresponding_institution_ids":["https://openalex.org/I173093425","https://openalex.org/I4210093821"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":3.049,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.9193013,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"24","issue":"1","first_page":"75","last_page":"75"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9232000112533569,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9232000112533569,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11358","display_name":"Dysphagia Assessment and Management","score":0.013000000268220901,"subfield":{"id":"https://openalex.org/subfields/3616","display_name":"Speech and Hearing"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10867","display_name":"Intensive Care Unit Cognitive Disorders","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dementia","display_name":"Dementia","score":0.7773364782333374},{"id":"https://openalex.org/keywords/positron-emission-tomography","display_name":"Positron emission tomography","score":0.7450491189956665},{"id":"https://openalex.org/keywords/posterior-cingulate","display_name":"Posterior cingulate","score":0.6682048439979553},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.6223205924034119},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5990831851959229},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.553338885307312},{"id":"https://openalex.org/keywords/temporal-lobe","display_name":"Temporal lobe","score":0.549669623374939},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"Cognitive impairment","score":0.504729151725769},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.4752597510814667},{"id":"https://openalex.org/keywords/standardized-uptake-value","display_name":"Standardized uptake value","score":0.45857009291648865},{"id":"https://openalex.org/keywords/cohort","display_name":"Cohort","score":0.45290738344192505},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.40024083852767944},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.37839651107788086},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.33723530173301697},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.33130669593811035},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.28037387132644653},{"id":"https://openalex.org/keywords/psychiatry","display_name":"Psychiatry","score":0.14615699648857117}],"concepts":[{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.7773364782333374},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.7450491189956665},{"id":"https://openalex.org/C2778733324","wikidata":"https://www.wikidata.org/wiki/Q2998088","display_name":"Posterior cingulate","level":3,"score":0.6682048439979553},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6223205924034119},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5990831851959229},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.553338885307312},{"id":"https://openalex.org/C2781099131","wikidata":"https://www.wikidata.org/wiki/Q744385","display_name":"Temporal lobe","level":3,"score":0.549669623374939},{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.504729151725769},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.4752597510814667},{"id":"https://openalex.org/C199374082","wikidata":"https://www.wikidata.org/wiki/Q907080","display_name":"Standardized uptake value","level":3,"score":0.45857009291648865},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.45290738344192505},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.40024083852767944},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.37839651107788086},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.33723530173301697},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.33130669593811035},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.28037387132644653},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.14615699648857117},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12880-024-01256-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01256-x","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01256-x","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:38549082","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38549082","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10976703","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10976703","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10976703/pdf/12880_2024_Article_1256.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Imaging","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:024701af4f824508bffbdcaa0eac96f8","is_oa":true,"landing_page_url":"https://doaj.org/article/024701af4f824508bffbdcaa0eac96f8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 24, Iss 1, Pp 1-14 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12880-024-01256-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01256-x","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01256-x","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5899999737739563,"id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G7688334757","display_name":null,"funder_award_id":"grants number 111-2314-B-182A-143","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"}],"funders":[{"id":"https://openalex.org/F4320322767","display_name":"Chang Gung Medical Foundation","ror":"https://ror.org/02verss31"},{"id":"https://openalex.org/F4320322795","display_name":"Ministry of Science and Technology, Taiwan","ror":"https://ror.org/02kv4zf79"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4393277909.pdf"},"referenced_works_count":74,"referenced_works":["https://openalex.org/W234029146","https://openalex.org/W1514308014","https://openalex.org/W1542623975","https://openalex.org/W1557858601","https://openalex.org/W1568421081","https://openalex.org/W1847168837","https://openalex.org/W1888169669","https://openalex.org/W1906782865","https://openalex.org/W1948376220","https://openalex.org/W1969787718","https://openalex.org/W1970322616","https://openalex.org/W1973526765","https://openalex.org/W1975914990","https://openalex.org/W1976817527","https://openalex.org/W1980175157","https://openalex.org/W1982231891","https://openalex.org/W1989378889","https://openalex.org/W1991952617","https://openalex.org/W1994605917","https://openalex.org/W2000658130","https://openalex.org/W2001436025","https://openalex.org/W2003690991","https://openalex.org/W2007847914","https://openalex.org/W2008854521","https://openalex.org/W2010152505","https://openalex.org/W2013643847","https://openalex.org/W2013676175","https://openalex.org/W2015151082","https://openalex.org/W2033242805","https://openalex.org/W2043768383","https://openalex.org/W2051357376","https://openalex.org/W2058046532","https://openalex.org/W2058161128","https://openalex.org/W2079205443","https://openalex.org/W2079749054","https://openalex.org/W2083880627","https://openalex.org/W2084550552","https://openalex.org/W2099489910","https://openalex.org/W2106931873","https://openalex.org/W2113708991","https://openalex.org/W2115017507","https://openalex.org/W2116698967","https://openalex.org/W2118097904","https://openalex.org/W2120740638","https://openalex.org/W2121930860","https://openalex.org/W2129497119","https://openalex.org/W2133703021","https://openalex.org/W2148080316","https://openalex.org/W2148283870","https://openalex.org/W2148677316","https://openalex.org/W2152163581","https://openalex.org/W2154394735","https://openalex.org/W2159122349","https://openalex.org/W2163932967","https://openalex.org/W2167311298","https://openalex.org/W2167840686","https://openalex.org/W2211971188","https://openalex.org/W2254886489","https://openalex.org/W2338257936","https://openalex.org/W2473213662","https://openalex.org/W2582524520","https://openalex.org/W2727312249","https://openalex.org/W2728134957","https://openalex.org/W2776130467","https://openalex.org/W2790567468","https://openalex.org/W2791819857","https://openalex.org/W2792166486","https://openalex.org/W2798054687","https://openalex.org/W2884795372","https://openalex.org/W2904012901","https://openalex.org/W2945458022","https://openalex.org/W3093546635","https://openalex.org/W4308773890","https://openalex.org/W6609114453"],"related_works":["https://openalex.org/W2327340211","https://openalex.org/W2027542625","https://openalex.org/W4292199793","https://openalex.org/W2282195379","https://openalex.org/W2089784006","https://openalex.org/W2295388821","https://openalex.org/W2102312026","https://openalex.org/W2885663991","https://openalex.org/W1984511692","https://openalex.org/W1970579671"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Based":[2],"on":[3],"a":[4,98,106],"longitudinal":[5,119],"cohort":[6],"design,":[7],"the":[8,118,136,177,182,230,233,239,256,268,288,302],"aim":[9],"of":[10,92,111,139,163,174,181,218,232,241],"this":[11],"study":[12],"was":[13,87,103,132,151,224],"to":[14,134,158,246,250,277,281,283],"investigate":[15],"whether":[16],"individual-based":[17,84,242],"18":[18,25,75,209,243,273],"F":[19],"fluorodeoxyglucose":[20],"positron":[21],"emission":[22],"tomography":[23],"(":[24],"F-FDG-PET)":[26],"regional":[27,112],"signals":[28],"can":[29],"predict":[30,247],"dementia":[31,213],"conversion":[32,205,214,249,282],"in":[33,255,267,272,287],"patients":[34,51,183],"with":[35,52,55,184,206,229,263],"mild":[36],"cognitive":[37,65,120,164,265],"impairment":[38],"(MCI).":[39],"Methods":[40],"We":[41],"included":[42],"44":[43],"MCI":[44,248,303],"converters":[45],"(MCI-C),":[46],"38":[47],"non-converters":[48],"(MCI-NC),":[49],"42":[50],"Alzheimer\u2019s":[53],"disease":[54],"dementia,":[56],"and":[57,74,142,194,223,258,291],"40":[58],"cognitively":[59],"normal":[60,99],"controls.":[61],"Data":[62],"from":[63,169],"annual":[64],"measurements,":[66],"3D":[67],"T1":[68],"magnetic":[69],"resonance":[70],"imaging":[71],"(MRI)":[72],"scans,":[73],"F-FDG-PET":[76,210,244,274],"scans":[77],"were":[78,126,260],"used":[79,133],"for":[80],"outcome":[81],"analysis.":[82],"An":[83],"FDG-PET":[85,100,253],"approach":[86],"applied":[88],"using":[89,97],"seven":[90],"volumes":[91],"interest":[93],"(VOIs),":[94],"Z":[95,107],"transformed":[96],"template.":[101],"Hypometabolism":[102],"defined":[104],"as":[105],"score":[108],"<":[109],"-2":[110],"standard":[113],"uptake":[114],"value":[115],"ratio.":[116],"For":[117],"test":[121],"scores,":[122],"generalized":[123],"estimating":[124],"equations":[125],"used.":[127],"A":[128],"linear":[129],"mixed-effects":[130],"model":[131],"compare":[135],"temporal":[137,187,293],"impact":[138],"cortical":[140,143],"hypometabolism":[141,203,211,286],"thickness":[144],"degeneration.":[145],"Results":[146],"The":[147,161],"clinical":[148],"follow-up":[149],"period":[150],"6.6":[152],"\u00b1":[153,220],"3.8":[154],"years":[155,173,222,279],"(range":[156],"3.1":[157],"16.0":[159],"years).":[160],"trend":[162],"decline":[165,266],"could":[166],"differentiate":[167],"MCI-C":[168,269],"MCI-NC":[170],"after":[171],"3":[172],"follow-up.":[175],"In":[176],"baseline":[178],"18F-FDG-PET":[179],"scan":[180],"MCI,":[185],"medial":[186],"lobe":[188],"(MTL;":[189],"94.7%":[190],"sensitivity,":[191,200],"80.5%":[192],"specificity)":[193,202],"posterior":[195],"cingulate":[196],"cortex":[197],"(PCC;":[198],"89.5%":[199],"73.1%":[201],"predicted":[204],"high":[207],"accuracy.":[208],"preceded":[212,298],"at":[215,301],"an":[216],"interval":[217],"3.70":[219],"1.68":[221],"earlier":[225],"than":[226],"volumetric":[227],"changes,":[228],"exception":[231],"MTL.":[234],"Conclusions":[235],"Our":[236],"finding":[237],"supports":[238],"use":[240],"analysis":[245],"dementia.":[251,284],"Reduced":[252],"metabolism":[254],"MTL":[257],"PCC":[259],"strongly":[261],"associated":[262],"future":[264],"group.":[270],"Changes":[271],"occurred":[275],"1":[276],"8":[278],"prior":[280],"Progressive":[285],"PCC,":[289],"precuneus":[290],"lateral":[292],"lobe,":[294],"but":[295],"not":[296],"MTL,":[297],"MRI":[299],"findings":[300],"stage.":[304]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2}],"updated_date":"2026-05-21T09:19:25.381259","created_date":"2025-10-10T00:00:00"}