{"id":"https://openalex.org/W4392641959","doi":"https://doi.org/10.1186/s12880-024-01236-1","title":"A noninvasive method for predicting clinically significant prostate cancer using magnetic resonance imaging combined with PRKY promoter methylation level: a machine learning study","display_name":"A noninvasive method for predicting clinically significant prostate cancer using magnetic resonance imaging combined with PRKY promoter methylation level: a machine learning study","publication_year":2024,"publication_date":"2024-03-11","ids":{"openalex":"https://openalex.org/W4392641959","doi":"https://doi.org/10.1186/s12880-024-01236-1","pmid":"https://pubmed.ncbi.nlm.nih.gov/38468226"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-024-01236-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01236-1","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01236-1","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01236-1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105231875","display_name":"Yufei Wang","orcid":"https://orcid.org/0000-0001-6659-9691"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]},{"id":"https://openalex.org/I4210124971","display_name":"Second Affiliated Hospital of Soochow University","ror":"https://ror.org/02xjrkt08","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124971"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yufei Wang","raw_affiliation_strings":["Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China","institution_ids":["https://openalex.org/I3923682","https://openalex.org/I4210124971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100444161","display_name":"Weifeng Liu","orcid":"https://orcid.org/0000-0002-7798-797X"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]},{"id":"https://openalex.org/I4210124971","display_name":"Second Affiliated Hospital of Soochow University","ror":"https://ror.org/02xjrkt08","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124971"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weifeng Liu","raw_affiliation_strings":["Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China","institution_ids":["https://openalex.org/I3923682","https://openalex.org/I4210124971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100662054","display_name":"Zeyu Chen","orcid":"https://orcid.org/0000-0001-6286-0581"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]},{"id":"https://openalex.org/I4210124971","display_name":"Second Affiliated Hospital of Soochow University","ror":"https://ror.org/02xjrkt08","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124971"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zeyu Chen","raw_affiliation_strings":["Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China","institution_ids":["https://openalex.org/I3923682","https://openalex.org/I4210124971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103686467","display_name":"Yachen Zang","orcid":null},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]},{"id":"https://openalex.org/I4210124971","display_name":"Second Affiliated Hospital of Soochow University","ror":"https://ror.org/02xjrkt08","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124971"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yachen Zang","raw_affiliation_strings":["Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China","institution_ids":["https://openalex.org/I3923682","https://openalex.org/I4210124971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101794358","display_name":"Lijun Xu","orcid":"https://orcid.org/0000-0002-5411-798X"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]},{"id":"https://openalex.org/I4210124971","display_name":"Second Affiliated Hospital of Soochow University","ror":"https://ror.org/02xjrkt08","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124971"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lijun Xu","raw_affiliation_strings":["Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China","institution_ids":["https://openalex.org/I3923682","https://openalex.org/I4210124971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100938065","display_name":"Zheng Dai","orcid":null},"institutions":[{"id":"https://openalex.org/I4210165047","display_name":"Hefei First People's Hospital","ror":"https://ror.org/05qwgjd68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210165047"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zheng Dai","raw_affiliation_strings":["Department of Urology, Hefei First People's Hopital, Hefei, Anhui Province, 230000, China. 568865870@qq.com","Department of Urology, Hefei First People's Hopital, Hefei, Anhui Province, 230000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Hefei First People's Hopital, Hefei, Anhui Province, 230000, China. 568865870@qq.com","institution_ids":["https://openalex.org/I4210165047"]},{"raw_affiliation_string":"Department of Urology, Hefei First People's Hopital, Hefei, Anhui Province, 230000, China","institution_ids":["https://openalex.org/I4210165047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111393763","display_name":"Yibin Zhou","orcid":"https://orcid.org/0009-0001-4187-0374"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]},{"id":"https://openalex.org/I4210124971","display_name":"Second Affiliated Hospital of Soochow University","ror":"https://ror.org/02xjrkt08","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124971"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yibin Zhou","raw_affiliation_strings":["Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China. 84853612@qq.com","Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China. 84853612@qq.com","institution_ids":["https://openalex.org/I3923682","https://openalex.org/I4210124971"]},{"raw_affiliation_string":"Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China","institution_ids":["https://openalex.org/I3923682","https://openalex.org/I4210124971"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016415183","display_name":"Jin Zhu","orcid":"https://orcid.org/0000-0002-3814-9885"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]},{"id":"https://openalex.org/I4210124971","display_name":"Second Affiliated Hospital of Soochow University","ror":"https://ror.org/02xjrkt08","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124971"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jin Zhu","raw_affiliation_strings":["Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China. urologist.zhujin@gmail.com","Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China. urologist.zhujin@gmail.com","institution_ids":["https://openalex.org/I3923682","https://openalex.org/I4210124971"]},{"raw_affiliation_string":"Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215000, China","institution_ids":["https://openalex.org/I3923682","https://openalex.org/I4210124971"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5100938065"],"corresponding_institution_ids":["https://openalex.org/I4210165047"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":2.2425,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.87646178,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"24","issue":"1","first_page":"60","last_page":"60"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9528999924659729,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9528999924659729,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.021400000900030136,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"Prostate cancer","score":0.7835164070129395},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.73211270570755},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.7009320259094238},{"id":"https://openalex.org/keywords/receiver-operating-characteristic","display_name":"Receiver operating characteristic","score":0.6224154233932495},{"id":"https://openalex.org/keywords/effective-diffusion-coefficient","display_name":"Effective diffusion coefficient","score":0.6121450662612915},{"id":"https://openalex.org/keywords/prostate","display_name":"Prostate","score":0.606441080570221},{"id":"https://openalex.org/keywords/prostate-biopsy","display_name":"Prostate biopsy","score":0.5878573656082153},{"id":"https://openalex.org/keywords/area-under-the-curve","display_name":"Area under the curve","score":0.5731101036071777},{"id":"https://openalex.org/keywords/methylation","display_name":"Methylation","score":0.533461332321167},{"id":"https://openalex.org/keywords/biopsy","display_name":"Biopsy","score":0.49163466691970825},{"id":"https://openalex.org/keywords/area-under-curve","display_name":"Area under curve","score":0.4668021500110626},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.44304358959198},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.4225611686706543},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.29591500759124756},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.2458040416240692},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.06839975714683533}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.7835164070129395},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.73211270570755},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.7009320259094238},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.6224154233932495},{"id":"https://openalex.org/C70816921","wikidata":"https://www.wikidata.org/wiki/Q258852","display_name":"Effective diffusion coefficient","level":3,"score":0.6121450662612915},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.606441080570221},{"id":"https://openalex.org/C2781217009","wikidata":"https://www.wikidata.org/wiki/Q4086927","display_name":"Prostate biopsy","level":4,"score":0.5878573656082153},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.5731101036071777},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.533461332321167},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.49163466691970825},{"id":"https://openalex.org/C3020225094","wikidata":"https://www.wikidata.org/wiki/Q80091","display_name":"Area under curve","level":3,"score":0.4668021500110626},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.44304358959198},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.4225611686706543},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.29591500759124756},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2458040416240692},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.06839975714683533},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038524","descriptor_name":"Diffusion Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038524","descriptor_name":"Diffusion Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038524","descriptor_name":"Diffusion Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038524","descriptor_name":"Diffusion Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038524","descriptor_name":"Diffusion Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12880-024-01236-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01236-1","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01236-1","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:38468226","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38468226","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10929135","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10929135","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10929135/pdf/12880_2024_Article_1236.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Imaging","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:cfe665ba6f02484db56505a8113711cd","is_oa":true,"landing_page_url":"https://doaj.org/article/cfe665ba6f02484db56505a8113711cd","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 24, Iss 1, Pp 1-10 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12880-024-01236-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01236-1","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01236-1","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8302806353","display_name":null,"funder_award_id":"GSWS2021016","funder_id":"https://openalex.org/F301560673","funder_display_name":"Suzhou Gusu Medical Youth Talent"}],"funders":[{"id":"https://openalex.org/F301560673","display_name":"Suzhou Gusu Medical Youth Talent","ror":null}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4392641959.pdf"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1545430154","https://openalex.org/W1608630302","https://openalex.org/W1811633403","https://openalex.org/W2009247871","https://openalex.org/W2054685854","https://openalex.org/W2055992848","https://openalex.org/W2095362469","https://openalex.org/W2097475056","https://openalex.org/W2103895549","https://openalex.org/W2104330091","https://openalex.org/W2129589381","https://openalex.org/W2136411301","https://openalex.org/W2156992415","https://openalex.org/W2409649574","https://openalex.org/W2513507045","https://openalex.org/W2588978745","https://openalex.org/W2911964244","https://openalex.org/W2921269376","https://openalex.org/W2922071185","https://openalex.org/W2949084192","https://openalex.org/W3026081260","https://openalex.org/W3059159028","https://openalex.org/W3088057579","https://openalex.org/W3097158220","https://openalex.org/W3118595823","https://openalex.org/W3144845145","https://openalex.org/W3153115921","https://openalex.org/W3180972814","https://openalex.org/W3181422783","https://openalex.org/W3210394817","https://openalex.org/W4281788587","https://openalex.org/W4283163956","https://openalex.org/W4311453640","https://openalex.org/W4315619028","https://openalex.org/W4362470737","https://openalex.org/W4386440831","https://openalex.org/W4386715618"],"related_works":["https://openalex.org/W3129055671","https://openalex.org/W2053081131","https://openalex.org/W2075569025","https://openalex.org/W3108466129","https://openalex.org/W2130905969","https://openalex.org/W2392162854","https://openalex.org/W3024816283","https://openalex.org/W2405447315","https://openalex.org/W2248642016","https://openalex.org/W205807182"],"abstract_inverted_index":{"BACKGROUND:":[0],"Traditional":[1],"process":[2],"for":[3,61,142,183],"clinically":[4],"significant":[5],"prostate":[6,39,46,53,181],"cancer":[7],"(csPCA)":[8],"diagnosis":[9],"relies":[10],"on":[11,271],"invasive":[12],"biopsy":[13,47],"and":[14,18,27,64,70,86,103,130,137,151,217,248,265],"may":[15],"bring":[16],"pain":[17],"complications.":[19],"Radiomic":[20],"features":[21,124],"of":[22,29,51,80,98,106,121,171,191,203,223,227,238],"magnetic":[23],"resonance":[24],"imaging":[25],"MRI":[26,71],"methylation":[28,135,251,268],"the":[30,52,76,104,146,152,158,161,172,185,204,228,239,243],"PRKY":[31,82,249,266],"promoter":[32,83,250,267],"were":[33,59,73,88,125,140],"found":[34],"to":[35,57,177],"be":[36,178],"associated":[37,179],"with":[38,180,215,242,260],"cancer.":[40],"METHODS:":[41],"Fifty-four":[42],"Patients":[43],"who":[44],"underwent":[45],"or":[48],"photoselective":[49],"vaporization":[50],"(PVP)":[54],"from":[55],"2022":[56],"2023":[58],"selected":[60,126],"this":[62],"study,":[63],"their":[65],"clinical":[66,138,218,246,263],"data,":[67],"blood":[68],"samples":[69],"images":[72],"obtained":[74],"before":[75],"operation.":[77],"Methylation":[78,169],"level":[79,170],"two":[81],"sites,":[84],"cg05618150":[85],"cg05163709,":[87],"tested":[89],"through":[90,127,145],"bisulfite":[91],"sequencing":[92],"PCR":[93],"(BSP).":[94],"The":[95,189,212,225,257],"PI-RADS":[96,244],"score":[97],"each":[99],"patient":[100],"was":[101,109,155,175,187,196,199,231,234],"estimated":[102],"region":[105],"interest":[107],"(ROI)":[108],"delineated":[110],"by":[111,118,157],"2":[112],"experienced":[113],"radiologists.":[114],"After":[115],"being":[116],"extracted":[117],"a":[119],"plug-in":[120],"3D-slicer,":[122],"radiomic":[123,133,261],"LASSCO":[128],"regression":[129],"t-test.":[131],"Selected":[132],"features,":[134,262],"levels":[136,252,269],"data":[139,219,247,264],"used":[141],"model":[143,213,230,240,258],"construction":[144],"random":[147],"forest":[148],"(RF)":[149],"algorithm,":[150],"predictive":[153,276],"efficiency":[154,277],"analyzed":[156],"area":[159],"under":[160],"receiver":[162],"operation":[163],"characteristic":[164],"(ROC)":[165],"curve":[166],"(AUC).":[167],"RESULTS:":[168],"site,":[173],"cg05618150,":[174],"observed":[176],"cancer,":[182],"which":[184,198,233],"AUC":[186,190,222,226],"0.74.":[188],"T2WI":[192,216],"in":[193,278],"csPCA":[194,279],"prediction":[195],"0.84,":[197],"higher":[200],"than":[201,236],"that":[202,237],"apparent":[205],"diffusion":[206],"coefficient":[207],"ADC":[208],"(AUC":[209,253],"=":[210,254],"0.81).":[211],"combined":[214,241],"reached":[220],"an":[221],"0.94.":[224],"T2WI-clinic-methylation-combined":[229],"0.97,":[232],"greater":[235],"score,":[245],"0.86).":[255],"CONCLUSIONS:":[256],"combining":[259],"based":[270],"machine":[272],"learning":[273],"had":[274],"high":[275],"diagnosis.":[280]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}