{"id":"https://openalex.org/W4392915159","doi":"https://doi.org/10.1186/s12880-024-01222-7","title":"Combining radiomics with thyroid imaging reporting and data system to predict lateral cervical lymph node metastases in medullary thyroid cancer","display_name":"Combining radiomics with thyroid imaging reporting and data system to predict lateral cervical lymph node metastases in medullary thyroid cancer","publication_year":2024,"publication_date":"2024-03-18","ids":{"openalex":"https://openalex.org/W4392915159","doi":"https://doi.org/10.1186/s12880-024-01222-7","pmid":"https://pubmed.ncbi.nlm.nih.gov/38500053"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-024-01222-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01222-7","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01222-7","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01222-7","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072795971","display_name":"Zhiqiang Liu","orcid":"https://orcid.org/0000-0002-9027-259X"},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiqiang Liu","raw_affiliation_strings":["Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101828494","display_name":"Xiwei Zhang","orcid":"https://orcid.org/0000-0001-7496-6666"},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiwei Zhang","raw_affiliation_strings":["Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056649068","display_name":"Xiaohui Zhao","orcid":"https://orcid.org/0000-0001-6852-0975"},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaohui Zhao","raw_affiliation_strings":["Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088117596","display_name":"Qianqian Guo","orcid":"https://orcid.org/0000-0001-8373-3530"},"institutions":[{"id":"https://openalex.org/I4210161528","display_name":"Qilu Hospital of Shandong University","ror":"https://ror.org/056ef9489","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161528"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qianqian Guo","raw_affiliation_strings":["Department of Ultrasound, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ultrasound, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China","institution_ids":["https://openalex.org/I4210161528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000493097","display_name":"Zhengjiang Li","orcid":"https://orcid.org/0000-0002-6639-3420"},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhengjiang Li","raw_affiliation_strings":["Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043350944","display_name":"Minghui Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Minghui Wei","raw_affiliation_strings":["Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112980388","display_name":"Lijuan Niu","orcid":"https://orcid.org/0000-0003-1286-5020"},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210089431","display_name":"National Cancer Center","ror":"https://ror.org/0065zqt33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089431"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Lijuan Niu","raw_affiliation_strings":["Department of Ultrasound, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China. niulijuan8197@126.com","Department of Ultrasound, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ultrasound, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China. niulijuan8197@126.com","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4210089431"]},{"raw_affiliation_string":"Department of Ultrasound, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063170111","display_name":"Changming An","orcid":"https://orcid.org/0000-0002-8353-4547"},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210089431","display_name":"National Cancer Center","ror":"https://ror.org/0065zqt33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089431"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Changming An","raw_affiliation_strings":["Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China. anchangming@cicams.ac.cn","Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China. anchangming@cicams.ac.cn","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4210089431"]},{"raw_affiliation_string":"Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P.R. China","institution_ids":["https://openalex.org/I200296433"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5063170111","https://openalex.org/A5112980388"],"corresponding_institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4210089431"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":{"value":2890,"currency":"USD","value_usd":2890},"fwci":2.1043,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.88316192,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"24","issue":"1","first_page":"64","last_page":"64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.8435301780700684},{"id":"https://openalex.org/keywords/radiomics","display_name":"Radiomics","score":0.7086719274520874},{"id":"https://openalex.org/keywords/thyroid-carcinoma","display_name":"Thyroid carcinoma","score":0.6192725300788879},{"id":"https://openalex.org/keywords/lymph-node","display_name":"Lymph node","score":0.6012252569198608},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.5927160978317261},{"id":"https://openalex.org/keywords/logistic-regression","display_name":"Logistic regression","score":0.5723490715026855},{"id":"https://openalex.org/keywords/medullary-cavity","display_name":"Medullary cavity","score":0.5651691555976868},{"id":"https://openalex.org/keywords/ultrasound","display_name":"Ultrasound","score":0.5335389375686646},{"id":"https://openalex.org/keywords/thyroid-cancer","display_name":"Thyroid cancer","score":0.5038837790489197},{"id":"https://openalex.org/keywords/thyroid","display_name":"Thyroid","score":0.4908219277858734},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.18254360556602478},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.16278564929962158}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8435301780700684},{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.7086719274520874},{"id":"https://openalex.org/C2993294228","wikidata":"https://www.wikidata.org/wiki/Q13632630","display_name":"Thyroid carcinoma","level":3,"score":0.6192725300788879},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.6012252569198608},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5927160978317261},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.5723490715026855},{"id":"https://openalex.org/C195121873","wikidata":"https://www.wikidata.org/wiki/Q1131385","display_name":"Medullary cavity","level":2,"score":0.5651691555976868},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.5335389375686646},{"id":"https://openalex.org/C2779761222","wikidata":"https://www.wikidata.org/wiki/Q826522","display_name":"Thyroid cancer","level":3,"score":0.5038837790489197},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.4908219277858734},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.18254360556602478},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16278564929962158}],"mesh":[{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D018278","descriptor_name":"Carcinoma, Neuroendocrine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018278","descriptor_name":"Carcinoma, Neuroendocrine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018278","descriptor_name":"Carcinoma, Neuroendocrine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018278","descriptor_name":"Carcinoma, Neuroendocrine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018278","descriptor_name":"Carcinoma, Neuroendocrine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12880-024-01222-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01222-7","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01222-7","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:38500053","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38500053","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10946103","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10946103","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Med Imaging","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:cc3bd84af5e74183a9f460de3daf8867","is_oa":true,"landing_page_url":"https://doaj.org/article/cc3bd84af5e74183a9f460de3daf8867","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 24, Iss 1, Pp 1-11 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12880-024-01222-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-024-01222-7","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-024-01222-7","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1199582937","display_name":null,"funder_award_id":"No.SZSM201911006","funder_id":"https://openalex.org/F4320335767","funder_display_name":"Sanming Project of Medicine in Shenzhen"},{"id":"https://openalex.org/G230229306","display_name":null,"funder_award_id":"No. SZSM201911006","funder_id":"https://openalex.org/F4320335767","funder_display_name":"Sanming Project of Medicine in Shenzhen"},{"id":"https://openalex.org/G6020717107","display_name":null,"funder_award_id":"SZSM201911006","funder_id":"https://openalex.org/F4320335767","funder_display_name":"Sanming Project of Medicine in Shenzhen"},{"id":"https://openalex.org/G8417849753","display_name":null,"funder_award_id":"82171965","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320326853","display_name":"Peking Union Medical College","ror":null},{"id":"https://openalex.org/F4320330603","display_name":"Cancer Foundation of China","ror":"https://ror.org/03qendm16"},{"id":"https://openalex.org/F4320335227","display_name":"Bijzonder Onderzoeksfonds UGent","ror":"https://ror.org/00cv9y106"},{"id":"https://openalex.org/F4320335767","display_name":"Sanming Project of Medicine in Shenzhen","ror":null}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4392915159.pdf"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1594241115","https://openalex.org/W1957988212","https://openalex.org/W1965143773","https://openalex.org/W2048482317","https://openalex.org/W2137760776","https://openalex.org/W2145150141","https://openalex.org/W2174661749","https://openalex.org/W2293412620","https://openalex.org/W2362373722","https://openalex.org/W2767128594","https://openalex.org/W2782686111","https://openalex.org/W2801302561","https://openalex.org/W2924421552","https://openalex.org/W3004788765","https://openalex.org/W3015691951","https://openalex.org/W3015843216","https://openalex.org/W3041570327","https://openalex.org/W3088334344","https://openalex.org/W3092176240","https://openalex.org/W3121140859","https://openalex.org/W3161408898","https://openalex.org/W3174879749","https://openalex.org/W4221008904","https://openalex.org/W4225275628","https://openalex.org/W4298142985","https://openalex.org/W4311047329","https://openalex.org/W4323355940"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2323164974","https://openalex.org/W3000891326","https://openalex.org/W2385345476","https://openalex.org/W2330865705","https://openalex.org/W2410375118","https://openalex.org/W2894644377","https://openalex.org/W2061719977","https://openalex.org/W1890834573","https://openalex.org/W2417238068"],"abstract_inverted_index":{"BACKGROUND:":[0],"Medullary":[1],"Thyroid":[2],"Carcinoma":[3],"(MTC)":[4],"is":[5,63],"a":[6,66,134,209,277,304],"rare":[7,314],"type":[8],"of":[9,14,60,91,177,196,203,211,236,284,316],"thyroid":[10,70,82,129,293,317],"cancer.":[11,318],"Accurate":[12],"prediction":[13,283],"lateral":[15],"cervical":[16],"lymph":[17],"node":[18],"metastases":[19],"(LCLNM)":[20],"in":[21,55,170,241,287],"MTC":[22,56,98,288],"patients":[23,32,99,289],"can":[24,79],"help":[25,308],"guide":[26,309],"surgical":[27],"decisions":[28,311],"and":[29,37,73,110,132,165,183,192,205,208,223,230,239,248,256,271],"ensure":[30],"that":[31,48,78,264],"receive":[33],"the":[34,88,118,157,161,166,175,178,194,197,220,242,285,298],"most":[35],"appropriate":[36],"effective":[38],"surgery.":[39],"To":[40],"our":[41],"knowledge,":[42],"no":[43],"studies":[44],"have":[45,275],"been":[46],"published":[47],"use":[49,80],"radiomics":[50,67,122,162,214],"analysis":[51,186],"to":[52,64,85,141,149,173,190,259,300,307],"forecast":[53],"LCLNM":[54,89,107,221,286],"patients.":[57],"The":[58,180,200,227],"purpose":[59],"this":[61,313],"study":[62],"develop":[65],"combined":[68],"with":[69],"imaging":[71],"reporting":[72],"data":[74],"system":[75],"(TI-RADS)":[76],"model":[77,159,163,168,280],"preoperative":[81,128,292],"ultrasound":[83,130,201,294],"images":[84],"noninvasively":[86],"predict":[87],"status":[90],"MTC.":[92],"METHODS:":[93],"We":[94,274],"retrospectively":[95],"included":[96],"218":[97],"who":[100],"were":[101,115,188,216],"confirmed":[102],"from":[103,127],"postoperative":[104],"pathology":[105],"as":[106,303],"negative":[108,222],"(n=111)":[109],"positive":[111,224],"(n=107).":[112],"Ultrasound":[113],"features":[114,123,145,202],"selected":[116,213],"using":[117,291],"Student's":[119],"t-test,":[120],"while":[121],"are":[124,146,250],"first":[125],"extracted":[126],"images,":[131],"then":[133,147],"two-step":[135],"feature":[136],"selection":[137],"approach":[138],"was":[139],"used":[140,148,189,302],"select":[142],"features.":[143],"These":[144],"establish":[150],"three":[151],"regularized":[152],"logistic":[153],"regression":[154],"models,":[155],"namely":[156],"TI-RADS":[158,206],"(TM),":[160],"(RM),":[164],"radiomics-TI-RADS":[167],"(RTM),":[169],"5-fold":[171,243],"cross-validation":[172,244],"determine":[174],"likelihood":[176],"LCLNM.":[179],"Delong's":[181],"test":[182],"decision":[184],"curve":[185],"(DCA)":[187],"evaluate":[191],"compare":[193],"performance":[195],"models.":[198],"RESULTS:":[199],"margin":[204],"level,":[207],"total":[210],"12":[212],"features,":[215],"significantly":[217],"different":[218],"between":[219],"groups":[225],"(p<0.05).":[226],"TM,":[228],"RM,":[229],"RTM":[231,249,265],"yielded":[232],"an":[233],"averaged":[234],"AUC":[235],"0.68\u00b10.05,":[237],"0.78\u00b10.06,":[238],"0.82\u00b10.05":[240],"dataset,":[245],"respectively.":[246],"RM":[247],"statistically":[251],"better":[252],"than":[253,269],"TM":[254,270],"(p<0.05":[255],"p<0.001)":[257],"according":[258],"Delong":[260],"test.":[261],"DCA":[262],"demonstrates":[263],"brings":[266],"more":[267],"benefit":[268],"RM.":[272],"CONCLUSIONS:":[273],"developed":[276],"joint":[278],"radiomics-based":[279],"for":[281,312],"noninvasive":[282],"solely":[290],"imaging.":[295],"It":[296],"has":[297],"potential":[299],"be":[301],"complementary":[305],"tool":[306],"treatment":[310],"form":[315]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2}],"updated_date":"2026-07-29T09:40:50.615796","created_date":"2025-10-10T00:00:00"}