{"id":"https://openalex.org/W2991428415","doi":"https://doi.org/10.1186/s12880-019-0391-8","title":"Evaluation of microvascular changes in the perifoveal vascular network using optical coherence tomography angiography (OCTA) in type I diabetes mellitus: a large scale prospective trial","display_name":"Evaluation of microvascular changes in the perifoveal vascular network using optical coherence tomography angiography (OCTA) in type I diabetes mellitus: a large scale prospective trial","publication_year":2019,"publication_date":"2019-11-21","ids":{"openalex":"https://openalex.org/W2991428415","doi":"https://doi.org/10.1186/s12880-019-0391-8","mag":"2991428415","pmid":"https://pubmed.ncbi.nlm.nih.gov/31752726"},"language":"en","primary_location":{"id":"doi:10.1186/s12880-019-0391-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-019-0391-8","pdf_url":"https://bmcmedimaging.biomedcentral.com/track/pdf/10.1186/s12880-019-0391-8.pdf","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedimaging.biomedcentral.com/track/pdf/10.1186/s12880-019-0391-8.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072951845","display_name":"Javier Zarranz\u2010Ventura","orcid":"https://orcid.org/0000-0003-2338-8143"},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Javier Zarranz-Ventura","raw_affiliation_strings":["Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain. jzarranz@hotmail.com","Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. jzarranz@hotmail.com","Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain"],"raw_orcid":"https://orcid.org/0000-0003-2338-8143","affiliations":[{"raw_affiliation_string":"Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain. jzarranz@hotmail.com","institution_ids":["https://openalex.org/I4210115097"]},{"raw_affiliation_string":"Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. jzarranz@hotmail.com","institution_ids":["https://openalex.org/I4210160192"]},{"raw_affiliation_string":"Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006696009","display_name":"Marina Barraso","orcid":null},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Marina Barraso","raw_affiliation_strings":["Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059262123","display_name":"An\u00edbal Al\u00e9-Chilet","orcid":"https://orcid.org/0000-0001-9479-4355"},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Anibal Al\u00e9-Chilet","raw_affiliation_strings":["Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009390091","display_name":"Teresa Hern\u00e1ndez","orcid":null},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Teresa Hernandez","raw_affiliation_strings":["Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106893932","display_name":"Cristian Oliva","orcid":null},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Cristian Oliva","raw_affiliation_strings":["Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041030664","display_name":"Jes\u00fas Gasc\u00f3n","orcid":null},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jesus Gasc\u00f3n","raw_affiliation_strings":["Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077525934","display_name":"Anna Sala\u2010Puigdollers","orcid":"https://orcid.org/0000-0001-5792-6937"},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Anna Sala-Puigdollers","raw_affiliation_strings":["Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]},{"raw_affiliation_string":"Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain","institution_ids":["https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055262226","display_name":"Marc Figueras\u2010Roca","orcid":"https://orcid.org/0000-0002-0548-0539"},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Marc Figueras-Roca","raw_affiliation_strings":["Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]},{"raw_affiliation_string":"Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain","institution_ids":["https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064547472","display_name":"Irene Vinagre","orcid":"https://orcid.org/0000-0001-8760-3370"},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Irene Vinagre","raw_affiliation_strings":["Diabetes Unit, Institut Cl\u00ednic de Malalties Digestives i Metaboliques (ICMDM), Hospital Clinic de Barcelona, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Unit, Institut Cl\u00ednic de Malalties Digestives i Metaboliques (ICMDM), Hospital Clinic de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Emilio Ortega","orcid":null},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Emilio Ortega","raw_affiliation_strings":["Diabetes Unit, Institut Cl\u00ednic de Malalties Digestives i Metaboliques (ICMDM), Hospital Clinic de Barcelona, Barcelona, Spain","Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Unit, Institut Cl\u00ednic de Malalties Digestives i Metaboliques (ICMDM), Hospital Clinic de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]},{"raw_affiliation_string":"Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain","institution_ids":["https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020185055","display_name":"Enric Esmatjes","orcid":"https://orcid.org/0000-0002-6329-5059"},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Enric Esmatjes","raw_affiliation_strings":["Diabetes Unit, Institut Cl\u00ednic de Malalties Digestives i Metaboliques (ICMDM), Hospital Clinic de Barcelona, Barcelona, Spain","Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Unit, Institut Cl\u00ednic de Malalties Digestives i Metaboliques (ICMDM), Hospital Clinic de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]},{"raw_affiliation_string":"Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain","institution_ids":["https://openalex.org/I4210160192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057566050","display_name":"Alfredo Ad\u00e1n","orcid":"https://orcid.org/0000-0002-0849-8814"},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Alfredo Adan","raw_affiliation_strings":["Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Cl\u00ednic d'Oftalmolog\u00eda (ICOF), Hospital Clinic de Barcelona, C/ Sabino Arana 1, 08028, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]},{"raw_affiliation_string":"Institut D'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain","institution_ids":["https://openalex.org/I4210160192"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5072951845"],"corresponding_institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210160192"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":2.6149,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.8889956,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"19","issue":"1","first_page":"91","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.8763999938964844,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.8763999938964844,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.04600000008940697,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.016300000250339508,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.7781389951705933},{"id":"https://openalex.org/keywords/diabetic-retinopathy","display_name":"Diabetic retinopathy","score":0.6887634992599487},{"id":"https://openalex.org/keywords/prospective-cohort-study","display_name":"Prospective cohort study","score":0.59100741147995},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"Diabetes mellitus","score":0.5792046785354614},{"id":"https://openalex.org/keywords/ophthalmology","display_name":"Ophthalmology","score":0.5004167556762695},{"id":"https://openalex.org/keywords/type-2-diabetes-mellitus","display_name":"Type 2 Diabetes Mellitus","score":0.48298895359039307},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.38580936193466187},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.3560420274734497},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.08847188949584961}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7781389951705933},{"id":"https://openalex.org/C2779829184","wikidata":"https://www.wikidata.org/wiki/Q631361","display_name":"Diabetic retinopathy","level":3,"score":0.6887634992599487},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.59100741147995},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5792046785354614},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.5004167556762695},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.48298895359039307},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38580936193466187},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3560420274734497},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.08847188949584961}],"mesh":[{"descriptor_ui":"D000072226","descriptor_name":"Computed Tomography Angiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000072226","descriptor_name":"Computed Tomography Angiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000072226","descriptor_name":"Computed Tomography Angiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003930","descriptor_name":"Diabetic Retinopathy","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003930","descriptor_name":"Diabetic Retinopathy","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003930","descriptor_name":"Diabetic Retinopathy","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003930","descriptor_name":"Diabetic Retinopathy","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003930","descriptor_name":"Diabetic Retinopathy","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003930","descriptor_name":"Diabetic Retinopathy","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005584","descriptor_name":"Fovea Centralis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005584","descriptor_name":"Fovea Centralis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005584","descriptor_name":"Fovea Centralis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005584","descriptor_name":"Fovea Centralis","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D005584","descriptor_name":"Fovea Centralis","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D005584","descriptor_name":"Fovea Centralis","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D006442","descriptor_name":"Glycated Hemoglobin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006442","descriptor_name":"Glycated Hemoglobin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006442","descriptor_name":"Glycated Hemoglobin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12880-019-0391-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-019-0391-8","pdf_url":"https://bmcmedimaging.biomedcentral.com/track/pdf/10.1186/s12880-019-0391-8.pdf","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:31752726","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31752726","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:diposit.ub.edu:2445/163125","is_oa":true,"landing_page_url":"http://hdl.handle.net/2445/163125","pdf_url":null,"source":{"id":"https://openalex.org/S4306401653","display_name":"Dip\u00f2sit Digital de la Universitat de Barcelona (Universitat de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I71999127","host_organization_name":"Universitat de Barcelona","host_organization_lineage":["https://openalex.org/I71999127"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Articles publicats en revistes (Medicina)","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:doaj.org/article:b39d5b3f66914adf9aed5915850ffd27","is_oa":true,"landing_page_url":"https://doaj.org/article/b39d5b3f66914adf9aed5915850ffd27","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Imaging, Vol 19, Iss 1, Pp 1-6 (2019)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:5833353","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6873669","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12880-019-0391-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12880-019-0391-8","pdf_url":"https://bmcmedimaging.biomedcentral.com/track/pdf/10.1186/s12880-019-0391-8.pdf","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6700000166893005,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G3861359036","display_name":null,"funder_award_id":"Beca FIS PI18/00518","funder_id":"https://openalex.org/F4320334923","funder_display_name":"Instituto de Salud Carlos III"},{"id":"https://openalex.org/G473031565","display_name":null,"funder_award_id":"201633.10","funder_id":"https://openalex.org/F4320310701","funder_display_name":"Fundaci\u00f3 la Marat\u00f3 de TV3"},{"id":"https://openalex.org/G5818485756","display_name":null,"funder_award_id":"PI18/00518","funder_id":"https://openalex.org/F4320334923","funder_display_name":"Instituto de Salud Carlos III"}],"funders":[{"id":"https://openalex.org/F4320310701","display_name":"Fundaci\u00f3 la Marat\u00f3 de TV3","ror":"https://ror.org/00t5xc355"},{"id":"https://openalex.org/F4320334923","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886"},{"id":"https://openalex.org/F4320335322","display_name":"European Regional Development Fund","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2991428415.pdf","grobid_xml":"https://content.openalex.org/works/W2991428415.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1269764409","https://openalex.org/W1931634044","https://openalex.org/W1992868980","https://openalex.org/W2006300976","https://openalex.org/W2016799658","https://openalex.org/W2027295650","https://openalex.org/W2027718081","https://openalex.org/W2046433337","https://openalex.org/W2048301902","https://openalex.org/W2076365332","https://openalex.org/W2082965216","https://openalex.org/W2136469949","https://openalex.org/W2277325960","https://openalex.org/W2318958718","https://openalex.org/W2326425955","https://openalex.org/W2334208756","https://openalex.org/W2588612709","https://openalex.org/W3021522287","https://openalex.org/W4319054054"],"related_works":["https://openalex.org/W4390515809","https://openalex.org/W2348573424","https://openalex.org/W3203337527","https://openalex.org/W2003316325","https://openalex.org/W2982442175","https://openalex.org/W2044207570","https://openalex.org/W3080453316","https://openalex.org/W1992007649","https://openalex.org/W2981103011","https://openalex.org/W2352634490"],"abstract_inverted_index":{"BACKGROUND:":[0],"Diabetic":[1],"retinopathy":[2],"(DR)":[3],"is":[4,32,184,218],"the":[5,25,45,51,63,92,149,162,166,177,187,213,222,225,228,236,251,259,262,282,295,302],"leading":[6],"cause":[7],"of":[8,20,44,53,56,62,74,78,91,113,116,148,165,181,212,227,235,271,285,297],"blindness":[9],"in":[10,24,155,161,176,239,250,281,300],"type":[11,156,286],"1":[12,157,287],"Diabetes":[13,163],"Mellitus":[14],"(DM)":[15],"patients,":[16,289],"as":[17,86,146,195,208,258,290],"a":[18,33,110,291],"consequence":[19],"impaired":[21],"blood":[22],"flow":[23],"retina.":[26],"Optical":[27],"coherence":[28],"tomography":[29],"angiography":[30],"(OCTA)":[31],"newly":[34],"developed,":[35],"non-invasive,":[36],"retinal":[37],"imaging":[38],"technique":[39],"that":[40],"permits":[41],"adequate":[42],"delineation":[43],"perifoveal":[46,229],"vascular":[47,230],"network.":[48],"It":[49],"allows":[50],"detection":[52,270],"paramacular":[54],"areas":[55],"capillary":[57],"non":[58],"perfusion":[59],"and/or":[60],"enlargement":[61],"foveal":[64],"avascular":[65],"zone":[66],"(FAZ),":[67],"representing":[68],"an":[69],"excellent":[70],"tool":[71],"for":[72],"assessment":[73],"DR.":[75],"The":[76,179],"relationship":[77,188,223],"these":[79,244,265,272],"microvascular":[80,256,273],"changes":[81,245,274],"with":[82,121],"systemic":[83,193,233],"factors":[84,207],"such":[85],"metabolic":[87,196],"control":[88,197],"or":[89,210,261],"duration":[90,211],"disease":[93],"still":[94],"needs":[95],"to":[96,174,185,220,241,279,293],"be":[97,144],"elucidated.":[98],"METHODS:":[99],"Prospective,":[100],"consecutive,":[101],"large-scale":[102],"OCTA":[103,114,276],"study.":[104],"A":[105],"complete":[106],"ocular":[107],"examination":[108],"including":[109],"comprehensive":[111],"series":[112],"images":[115],"different":[117],"scan":[118],"sizes":[119],"captured":[120],"2":[122],"OCT":[123],"devices":[124],"(Cirrus":[125],"HD-OCT,":[126],"Carl":[127],"Zeiss":[128],"Meditec,":[129],"Dublin,":[130],"CA,":[131],"USA,":[132],"and":[133,192,203,232,238,304],"Triton":[134],"Deep":[135],"Range":[136],"Imaging":[137],"OCT,":[138],"Topcon":[139],"Corp,":[140],"Topcon,":[141],"Japan)":[142],"will":[143],"obtained":[145],"part":[147],"yearly":[150],"routine":[151],"follow":[152],"up":[153],"visits":[154],"DM":[158],"patients":[159],"seen":[160],"Unit":[164],"Endocrinology":[167],"department":[168],"which":[169],"give":[170],"written":[171],"informed":[172],"consent":[173],"participate":[175],"project.":[178],"aim":[180],"this":[182],"study":[183,217,242],"investigate":[186,221],"between":[189,224],"OCTA-derived":[190],"parameters":[191],"factors,":[194],"(Hb1Ac,":[198],"lipid":[199],"profile,":[200],"cholesterol,":[201],"etc),":[202],"other":[204,305],"relevant":[205],"clinical":[206],"demographics":[209],"disease.":[214],"DISCUSSION:":[215],"This":[216],"directed":[219],"status":[226],"network":[231],"markers":[234],"disease,":[237,257],"particular":[240],"whether":[243],"reflect":[246],"those":[247],"occurring":[248],"elsewhere":[249],"body":[252],"affected":[253],"by":[254,275],"diabetic":[255,288],"kidneys":[260],"brain.":[263],"If":[264],"relationships":[266],"were":[267],"demonstrated,":[268],"early":[269],"could":[277],"lead":[278],"modifications":[280],"pharmacological":[283],"management":[284],"way":[292],"reduce":[294],"risk":[296],"future":[298],"complications":[299],"both":[301],"eye":[303],"organs.":[306],"TRIAL":[307],"REGISTRATION:":[308],"ClinicalTrials.gov,":[309],"trial":[310],"number":[311],"NCT03422965.":[312]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}