{"id":"https://openalex.org/W4406307544","doi":"https://doi.org/10.1186/s12859-025-06040-4","title":"MDFGNN-SMMA: prediction of potential small molecule-miRNA associations based on multi-source data fusion and graph neural networks","display_name":"MDFGNN-SMMA: prediction of potential small molecule-miRNA associations based on multi-source data fusion and graph neural networks","publication_year":2025,"publication_date":"2025-01-13","ids":{"openalex":"https://openalex.org/W4406307544","doi":"https://doi.org/10.1186/s12859-025-06040-4","pmid":"https://pubmed.ncbi.nlm.nih.gov/39806287"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-025-06040-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-025-06040-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-025-06040-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-025-06040-4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078459865","display_name":"Jianwei Li","orcid":"https://orcid.org/0000-0002-4523-1692"},"institutions":[{"id":"https://openalex.org/I184843921","display_name":"Hebei University of Technology","ror":"https://ror.org/018hded08","country_code":"CN","type":"education","lineage":["https://openalex.org/I184843921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianwei Li","raw_affiliation_strings":["School of Artificial Intelligence, Hebei University of Technology, Tianjin, 300401, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Artificial Intelligence, Hebei University of Technology, Tianjin, 300401, China","institution_ids":["https://openalex.org/I184843921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042793959","display_name":"X Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I184843921","display_name":"Hebei University of Technology","ror":"https://ror.org/018hded08","country_code":"CN","type":"education","lineage":["https://openalex.org/I184843921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xukun Zhang","raw_affiliation_strings":["School of Artificial Intelligence, Hebei University of Technology, Tianjin, 300401, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Artificial Intelligence, Hebei University of Technology, Tianjin, 300401, China","institution_ids":["https://openalex.org/I184843921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100451293","display_name":"Bing Li","orcid":"https://orcid.org/0000-0002-7896-7903"},"institutions":[{"id":"https://openalex.org/I184843921","display_name":"Hebei University of Technology","ror":"https://ror.org/018hded08","country_code":"CN","type":"education","lineage":["https://openalex.org/I184843921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bing Li","raw_affiliation_strings":["School of Artificial Intelligence, Hebei University of Technology, Tianjin, 300401, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Artificial Intelligence, Hebei University of Technology, Tianjin, 300401, China","institution_ids":["https://openalex.org/I184843921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100753798","display_name":"Ziyu Li","orcid":"https://orcid.org/0000-0001-5580-4979"},"institutions":[{"id":"https://openalex.org/I184843921","display_name":"Hebei University of Technology","ror":"https://ror.org/018hded08","country_code":"CN","type":"education","lineage":["https://openalex.org/I184843921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ziyu Li","raw_affiliation_strings":["School of Artificial Intelligence, Hebei University of Technology, Tianjin, 300401, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Artificial Intelligence, Hebei University of Technology, Tianjin, 300401, China","institution_ids":["https://openalex.org/I184843921"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100728360","display_name":"Zhenzhen Chen","orcid":"https://orcid.org/0000-0003-2093-4639"},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210119028","display_name":"Beijing Anzhen Hospital","ror":"https://ror.org/02h2j1586","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210119028"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhenzhen Chen","raw_affiliation_strings":["Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital of Capital Medical University, Beijing, 101100, China. chenzhenzhen@bjmu.edu.cn","Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital of Capital Medical University, Beijing, 101100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital of Capital Medical University, Beijing, 101100, China. chenzhenzhen@bjmu.edu.cn","institution_ids":["https://openalex.org/I4210119028"]},{"raw_affiliation_string":"Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital of Capital Medical University, Beijing, 101100, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210119028"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100728360"],"corresponding_institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210119028"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":0.7361,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.69597648,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"26","issue":"1","first_page":"13","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.5386999845504761,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.5386999845504761,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.3061999976634979,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.026000000536441803,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5650451183319092},{"id":"https://openalex.org/keywords/adjacency-matrix","display_name":"Adjacency matrix","score":0.4968607723712921},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.48460158705711365},{"id":"https://openalex.org/keywords/feature-vector","display_name":"Feature vector","score":0.46244627237319946},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.45900484919548035},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.45637595653533936},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.4469791054725647},{"id":"https://openalex.org/keywords/adjacency-list","display_name":"Adjacency list","score":0.4226272702217102},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4145970046520233},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.40612709522247314},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.3918006122112274},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3015980124473572},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.24529454112052917},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.19939857721328735}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5650451183319092},{"id":"https://openalex.org/C180356752","wikidata":"https://www.wikidata.org/wiki/Q727035","display_name":"Adjacency matrix","level":3,"score":0.4968607723712921},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.48460158705711365},{"id":"https://openalex.org/C83665646","wikidata":"https://www.wikidata.org/wiki/Q42139305","display_name":"Feature vector","level":2,"score":0.46244627237319946},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.45900484919548035},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.45637595653533936},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4469791054725647},{"id":"https://openalex.org/C110484373","wikidata":"https://www.wikidata.org/wiki/Q264398","display_name":"Adjacency list","level":2,"score":0.4226272702217102},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4145970046520233},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.40612709522247314},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.3918006122112274},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3015980124473572},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24529454112052917},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.19939857721328735},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000098422","descriptor_name":"Graph Neural Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098422","descriptor_name":"Graph Neural Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D054852","descriptor_name":"Small Molecule Libraries","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D054852","descriptor_name":"Small Molecule Libraries","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D054852","descriptor_name":"Small Molecule Libraries","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D054852","descriptor_name":"Small Molecule Libraries","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D054852","descriptor_name":"Small Molecule Libraries","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-025-06040-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-025-06040-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-025-06040-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39806287","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39806287","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11730471","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11730471","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11730471/pdf/12859_2025_Article_6040.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:801d4bca4994476c82e1dec29e02b5e9","is_oa":true,"landing_page_url":"https://doaj.org/article/801d4bca4994476c82e1dec29e02b5e9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 26, Iss 1, Pp 1-23 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12859-025-06040-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-025-06040-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-025-06040-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3424519559","display_name":"\u57fa\u4e8e\u591a\u6e90\u5f02\u6784\u4fe1\u606f\u878d\u5408\u7684\u957f\u975e\u7f16\u7801RNA\u529f\u80fd\u5bcc\u96c6\u5206\u6790\u65b9\u6cd5\u7814\u7a76","funder_award_id":"62072154","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4618886899","display_name":null,"funder_award_id":"62202330","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4406307544.pdf"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W144423133","https://openalex.org/W1543790510","https://openalex.org/W1889514258","https://openalex.org/W1974254202","https://openalex.org/W1975441976","https://openalex.org/W1984328540","https://openalex.org/W2021748110","https://openalex.org/W2059357290","https://openalex.org/W2106210472","https://openalex.org/W2146943422","https://openalex.org/W2295124130","https://openalex.org/W2443187137","https://openalex.org/W2588025094","https://openalex.org/W2624827575","https://openalex.org/W2747907311","https://openalex.org/W2896907688","https://openalex.org/W2898440040","https://openalex.org/W2921814376","https://openalex.org/W2937766145","https://openalex.org/W2946707752","https://openalex.org/W2946714259","https://openalex.org/W2970757764","https://openalex.org/W3012491561","https://openalex.org/W3040152568","https://openalex.org/W3139034792","https://openalex.org/W3162614041","https://openalex.org/W3195016804","https://openalex.org/W3195937938","https://openalex.org/W3200707343","https://openalex.org/W3202551657","https://openalex.org/W3206601677","https://openalex.org/W3207938624","https://openalex.org/W3210024567","https://openalex.org/W4200395012","https://openalex.org/W4281729754","https://openalex.org/W4307468223","https://openalex.org/W4310612907","https://openalex.org/W4388522247","https://openalex.org/W4388615774"],"related_works":["https://openalex.org/W4213150077","https://openalex.org/W2369410163","https://openalex.org/W2059018062","https://openalex.org/W2604585036","https://openalex.org/W2078477160","https://openalex.org/W1989103179","https://openalex.org/W1991172810","https://openalex.org/W125803343","https://openalex.org/W2153421018","https://openalex.org/W2117632582"],"abstract_inverted_index":{"BACKGROUND:":[0],"MicroRNAs":[1],"(miRNAs)":[2],"are":[3],"pivotal":[4],"in":[5,46,197],"the":[6,26,40,106,120,149,158,173,193,205,214,219,234,257],"initiation":[7],"and":[8,14,28,63,85,125,132,142,155,177,202,243,247,256],"progression":[9],"of":[10,31,81,182,199,208,221],"complex":[11],"human":[12],"diseases":[13],"have":[15],"been":[16],"identified":[17],"as":[18,165],"targets":[19],"for":[20,35,42,67,95,110,123,153,167],"small":[21,96],"molecule":[22],"(SM)":[23],"drugs.":[24],"However,":[25],"expensive":[27],"time-intensive":[29],"characteristics":[30],"conventional":[32],"experimental":[33,206],"techniques":[34],"identifying":[36],"SM-miRNA":[37,75],"associations":[38,174],"highlight":[39],"necessity":[41],"efficient":[43],"computational":[44],"methodologies":[45],"this":[47,51],"field.":[48],"RESULTS:":[49],"In":[50],"study,":[52],"we":[53],"proposed":[54],"a":[55,138,168],"deep":[56],"learning":[57],"method":[58],"called":[59],"Multi-source":[60],"Data":[61],"Fusion":[62],"Graph":[64],"Neural":[65],"Networks":[66],"Small":[68],"Molecule-MiRNA":[69],"Association":[70],"(MDFGNN-SMMA)":[71],"to":[72,90,104,118,147,171,192],"predict":[73,172],"potential":[74],"associations.":[76],"Firstly,":[77],"MDFGNN-SMMA":[78,183,222],"extracted":[79],"features":[80,101],"Atom":[82],"Pairs":[83],"fingerprints":[84,89],"Molecular":[86],"ACCess":[87],"System":[88],"derive":[91],"fusion":[92],"feature":[93,108,130,151,161],"vectors":[94,109,131,152,162],"molecules":[97],"(SMs).":[98],"The":[99,180,229],"K-mer":[100],"were":[102,116,135,145,163,251],"employed":[103],"generate":[105,148],"initial":[107],"miRNAs.":[111,156,178],"Secondly,":[112],"cosine":[113],"similarity":[114],"measures":[115],"computed":[117],"construct":[119],"adjacency":[121,133],"matrices":[122,134],"SMs":[124,154,176],"miRNAs,":[126,249],"respectively.":[127],"Thirdly,":[128],"these":[129],"input":[136,166],"into":[137],"model":[139],"comprising":[140],"GAT":[141],"GraphSAGE,":[143],"which":[144],"utilized":[146,164],"final":[150,160],"Finally,":[157],"averaged":[159],"multilayer":[169],"perceptron":[170],"between":[175],"CONCLUSIONS:":[179],"performance":[181],"was":[184,223],"assessed":[185],"using":[186],"10-fold":[187],"cross-validation,":[188],"demonstrating":[189],"superior":[190],"compared":[191],"four":[194],"state-of-the-art":[195],"models":[196],"terms":[198],"both":[200],"AUC":[201],"AUPR.":[203],"Moreover,":[204],"results":[207],"an":[209],"independent":[210],"test":[211],"set":[212],"confirmed":[213],"model's":[215],"generalization":[216],"capability.":[217],"Additionally,":[218],"efficacy":[220],"substantiated":[224],"through":[225],"three":[226],"case":[227],"studies.":[228],"findings":[230],"indicated":[231],"that":[232],"among":[233],"top":[235],"50":[236],"predicted":[237],"miRNAs":[238],"associated":[239],"with":[240],"Cisplatin,":[241],"5-Fluorouracil,":[242],"Doxorubicin,":[244],"42,":[245],"36,":[246],"36":[248],"respectively,":[250],"corroborated":[252],"by":[253],"existing":[254],"literature":[255],"RNAInter":[258],"database.":[259]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-08-05T07:39:15.569665","created_date":"2025-10-10T00:00:00"}