{"id":"https://openalex.org/W4390061859","doi":"https://doi.org/10.1186/s12859-023-05624-2","title":"IgMAT: immunoglobulin sequence multi-species annotation tool for any species including those with incomplete antibody annotation or unusual characteristics","display_name":"IgMAT: immunoglobulin sequence multi-species annotation tool for any species including those with incomplete antibody annotation or unusual characteristics","publication_year":2023,"publication_date":"2023-12-21","ids":{"openalex":"https://openalex.org/W4390061859","doi":"https://doi.org/10.1186/s12859-023-05624-2","pmid":"https://pubmed.ncbi.nlm.nih.gov/38129777"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-023-05624-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05624-2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05624-2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05624-2","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088855521","display_name":"Daniel Dorey-Robinson","orcid":null},"institutions":[{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Daniel Dorey-Robinson","raw_affiliation_strings":["The Pirbright Institute, Pirbright, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Pirbright Institute, Pirbright, UK","institution_ids":["https://openalex.org/I1287548271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069198387","display_name":"Giuseppe Maccari","orcid":"https://orcid.org/0000-0002-2894-3583"},"institutions":[{"id":"https://openalex.org/I2800598996","display_name":"Anthony Nolan","ror":"https://ror.org/043bfms20","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2800598996"]},{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Giuseppe Maccari","raw_affiliation_strings":["Anthony Nolan Research Institute, London, UK","The Pirbright Institute, Pirbright, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anthony Nolan Research Institute, London, UK","institution_ids":["https://openalex.org/I2800598996"]},{"raw_affiliation_string":"The Pirbright Institute, Pirbright, UK","institution_ids":["https://openalex.org/I1287548271"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062606439","display_name":"John A. Hammond","orcid":"https://orcid.org/0000-0002-2213-3248"},"institutions":[{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John A. Hammond","raw_affiliation_strings":["The Pirbright Institute, Pirbright, UK. john.hammond@pirbright.ac.uk","The Pirbright Institute, Pirbright, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Pirbright Institute, Pirbright, UK. john.hammond@pirbright.ac.uk","institution_ids":["https://openalex.org/I1287548271"]},{"raw_affiliation_string":"The Pirbright Institute, Pirbright, UK","institution_ids":["https://openalex.org/I1287548271"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5088855521"],"corresponding_institution_ids":["https://openalex.org/I1287548271"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":2545,"currency":"EUR","value_usd":2744},"fwci":1.1224,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.79815486,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"24","issue":"1","first_page":"491","last_page":"491"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.29600000381469727,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.29600000381469727,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.12600000202655792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.09749999642372131,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.8173702955245972},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.598558783531189},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5844383835792542},{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.5357080698013306},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5027720928192139},{"id":"https://openalex.org/keywords/antibody-repertoire","display_name":"Antibody Repertoire","score":0.4978516101837158},{"id":"https://openalex.org/keywords/scripting-language","display_name":"Scripting language","score":0.4875602126121521},{"id":"https://openalex.org/keywords/gene-annotation","display_name":"Gene Annotation","score":0.4248628616333008},{"id":"https://openalex.org/keywords/complementarity","display_name":"Complementarity (molecular biology)","score":0.42367178201675415},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3892025649547577},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.333601176738739},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.26069021224975586},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2082943320274353},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1705956757068634},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16734352707862854},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.16577938199043274}],"concepts":[{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.8173702955245972},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.598558783531189},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5844383835792542},{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.5357080698013306},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5027720928192139},{"id":"https://openalex.org/C2910693471","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody Repertoire","level":3,"score":0.4978516101837158},{"id":"https://openalex.org/C61423126","wikidata":"https://www.wikidata.org/wiki/Q187432","display_name":"Scripting language","level":2,"score":0.4875602126121521},{"id":"https://openalex.org/C2908923196","wikidata":"https://www.wikidata.org/wiki/Q5205742","display_name":"Gene Annotation","level":4,"score":0.4248628616333008},{"id":"https://openalex.org/C202269582","wikidata":"https://www.wikidata.org/wiki/Q2644277","display_name":"Complementarity (molecular biology)","level":2,"score":0.42367178201675415},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3892025649547577},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.333601176738739},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.26069021224975586},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2082943320274353},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1705956757068634},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16734352707862854},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.16577938199043274}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-023-05624-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05624-2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05624-2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:38129777","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38129777","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10740263","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10740263","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10740263/pdf/12859_2023_Article_5624.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:875da9652017451c9b98474de413dbd9","is_oa":true,"landing_page_url":"https://doaj.org/article/875da9652017451c9b98474de413dbd9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 24, Iss 1, Pp 1-8 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12859-023-05624-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05624-2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05624-2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","score":0.5600000023841858,"display_name":"Life in Land"}],"awards":[{"id":"https://openalex.org/G1294961325","display_name":null,"funder_award_id":"BBS/E/I/00007038","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G1491676723","display_name":null,"funder_award_id":"BBS/E/I/00007030","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G243541167","display_name":null,"funder_award_id":"OPP1192992","funder_id":"https://openalex.org/F4320306137","funder_display_name":"Bill and Melinda Gates Foundation"},{"id":"https://openalex.org/G3672123408","display_name":"Securing and developing the IPD-MHC database to enhance research into livestock diseases","funder_award_id":"BB/M011488/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G6463071208","display_name":null,"funder_award_id":"BB/M011488/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G8498315847","display_name":null,"funder_award_id":"BBS/E/I/00001710","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320306137","display_name":"Bill and Melinda Gates Foundation","ror":"https://ror.org/0456r8d26"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390061859.pdf"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1855237549","https://openalex.org/W1975670646","https://openalex.org/W2031132894","https://openalex.org/W2082947088","https://openalex.org/W2085366207","https://openalex.org/W2110505462","https://openalex.org/W2115122333","https://openalex.org/W2132580736","https://openalex.org/W2513558090","https://openalex.org/W2774606440","https://openalex.org/W2783812192","https://openalex.org/W2904478593","https://openalex.org/W2993744977","https://openalex.org/W3111287171","https://openalex.org/W4229892776"],"related_works":["https://openalex.org/W3023169329","https://openalex.org/W4389470870","https://openalex.org/W2782165897","https://openalex.org/W4300438041","https://openalex.org/W2054104202","https://openalex.org/W2139703748","https://openalex.org/W2761254753","https://openalex.org/W1024825291","https://openalex.org/W2188981919","https://openalex.org/W3084909426"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1],"advent":[2],"and":[3,16,33,54,151,164,177],"continual":[4],"improvement":[5],"of":[6,19,38,133,145,153,158],"high-throughput":[7],"sequencing":[8,14],"technologies":[9],"has":[10],"made":[11],"immunoglobulin":[12,122,165],"repertoire":[13],"accessible":[15],"informative":[17],"regardless":[18],"study":[20],"species.":[21,171],"However,":[22],"to":[23,82,119,137,203],"fully":[24,175],"map":[25],"dynamic":[26],"changes":[27],"in":[28,206],"polyclonal":[29],"responses":[30],"precise":[31],"framework":[32],"complementarity":[34],"determining":[35],"region":[36],"annotation":[37,45],"rearranging":[39],"genes":[40],"is":[41,174],"pivotal.":[42],"Most":[43],"sequence":[44,166],"tools":[46,80],"are":[47],"designed":[48],"primarily":[49],"for":[50,185],"use":[51,59],"with":[52,61,91,95],"human":[53],"mouse":[55],"antibody":[56,143],"sequences":[57,123,159],"which":[58,69,103],"databases":[60,136],"fixed":[62],"species":[63,93,141],"lists,":[64],"applying":[65],"very":[66,89],"specific":[67],"assumptions":[68],"select":[70],"against":[71],"unique":[72],"structural":[73,162],"characteristics.":[74],"For":[75],"this":[76],"reason,":[77],"data":[78,86,163],"agnostic":[79],"able":[81],"learn":[83],"from":[84,124,161,168],"presented":[85],"can":[87,191],"be":[88,192,204],"useful":[90],"new":[92],"or":[94,198],"novel":[96],"datasets.":[97],"RESULTS:":[98],"We":[99],"have":[100],"developed":[101],"IgMAT,":[102,154],"utilises":[104],"a":[105,116,195,200],"reduced":[106],"amino":[107],"acid":[108],"alphabet,":[109],"that":[110],"incorporates":[111],"multiple":[112],"HMM":[113],"alignments":[114],"into":[115],"single":[117],"consensus":[118],"automatically":[120],"annotate":[121],"most":[125],"organisms.":[126],"Additionally,":[127],"the":[128,131,140,149],"software":[129],"allows":[130],"incorporation":[132],"user":[134],"defined":[135],"better":[138],"represent":[139],"and/or":[142],"class":[144],"interest.":[146],"To":[147],"demonstrate":[148],"accuracy":[150],"utility":[152],"we":[155],"present":[156],"analysis":[157],"extracted":[160],"datasets":[167],"several":[169],"different":[170],"CONCLUSIONS:":[172],"IgMAT":[173],"open-sourced":[176],"freely":[178],"available":[179],"on":[180],"GitHub":[181],"(":[182],"https://github.com/TPI-Immunogenetics/igmat":[183],")":[184],"download":[186],"under":[187],"GPLv3":[188],"license.":[189],"It":[190],"used":[193],"as":[194,199],"CLI":[196],"application":[197],"python":[201],"module":[202],"integrated":[205],"custom":[207],"scripts.":[208]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1}],"updated_date":"2026-05-19T08:33:51.333923","created_date":"2025-10-10T00:00:00"}