{"id":"https://openalex.org/W4388441919","doi":"https://doi.org/10.1186/s12859-023-05545-0","title":"Ab initio protein structure prediction: the necessary presence of external force field as it is delivered by Hsp40 chaperone","display_name":"Ab initio protein structure prediction: the necessary presence of external force field as it is delivered by Hsp40 chaperone","publication_year":2023,"publication_date":"2023-11-06","ids":{"openalex":"https://openalex.org/W4388441919","doi":"https://doi.org/10.1186/s12859-023-05545-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/37932669"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-023-05545-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05545-0","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05545-0","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05545-0","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087239926","display_name":"Irena Roterman","orcid":"https://orcid.org/0000-0003-3652-9099"},"institutions":[{"id":"https://openalex.org/I126596746","display_name":"Jagiellonian University","ror":"https://ror.org/03bqmcz70","country_code":"PL","type":"education","lineage":["https://openalex.org/I126596746"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Irena Roterman","raw_affiliation_strings":["Department of Bioinformatics and Telemedicine, Jagiellonian University - Medical College, Medyczna 7, 30-688, Krakow, Poland. myroterm@cyf-kr.edu.pl","Department of Bioinformatics and Telemedicine, Jagiellonian University - Medical College, Medyczna 7, 30-688, Krakow, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics and Telemedicine, Jagiellonian University - Medical College, Medyczna 7, 30-688, Krakow, Poland. myroterm@cyf-kr.edu.pl","institution_ids":["https://openalex.org/I126596746"]},{"raw_affiliation_string":"Department of Bioinformatics and Telemedicine, Jagiellonian University - Medical College, Medyczna 7, 30-688, Krakow, Poland","institution_ids":["https://openalex.org/I126596746"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045740283","display_name":"Katarzyna St\u0105por","orcid":"https://orcid.org/0000-0003-3003-6592"},"institutions":[{"id":"https://openalex.org/I119004910","display_name":"Silesian University of Technology","ror":"https://ror.org/02dyjk442","country_code":"PL","type":"education","lineage":["https://openalex.org/I119004910"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Katarzyna Stapor","raw_affiliation_strings":["Department of Applied Informatics, Silesian University of Technology, Gliwice, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Informatics, Silesian University of Technology, Gliwice, Poland","institution_ids":["https://openalex.org/I119004910"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027144155","display_name":"Leszek Konieczny","orcid":null},"institutions":[{"id":"https://openalex.org/I126596746","display_name":"Jagiellonian University","ror":"https://ror.org/03bqmcz70","country_code":"PL","type":"education","lineage":["https://openalex.org/I126596746"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Leszek Konieczny","raw_affiliation_strings":["Chair of Medical Biochemistry, Jagiellonian University - Medical College, Kopernika 7, 31-034, Krakow, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chair of Medical Biochemistry, Jagiellonian University - Medical College, Kopernika 7, 31-034, Krakow, Poland","institution_ids":["https://openalex.org/I126596746"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5087239926"],"corresponding_institution_ids":["https://openalex.org/I126596746"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.695,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.84556429,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"24","issue":"1","first_page":"418","last_page":"418"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.8011999726295471,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.8011999726295471,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.1404999941587448,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.014700000174343586,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-data-bank","display_name":"Protein Data Bank (RCSB PDB)","score":0.6590973138809204},{"id":"https://openalex.org/keywords/protein-folding","display_name":"Protein folding","score":0.6555218696594238},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.5737043023109436},{"id":"https://openalex.org/keywords/force-field","display_name":"Force field (fiction)","score":0.565153181552887},{"id":"https://openalex.org/keywords/chaperone","display_name":"Chaperone (clinical)","score":0.5628089904785156},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.5446748733520508},{"id":"https://openalex.org/keywords/ab-initio","display_name":"Ab initio","score":0.5399096012115479},{"id":"https://openalex.org/keywords/crystallography","display_name":"Crystallography","score":0.4455931484699249},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.433879554271698},{"id":"https://openalex.org/keywords/protein-structure-prediction","display_name":"Protein structure prediction","score":0.4233027398586273},{"id":"https://openalex.org/keywords/biomolecule","display_name":"Biomolecule","score":0.41595518589019775},{"id":"https://openalex.org/keywords/chemical-physics","display_name":"Chemical physics","score":0.4016708731651306},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.34084784984588623},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.22129642963409424},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13665011525154114},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.13365629315376282},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.07434126734733582}],"concepts":[{"id":"https://openalex.org/C65556437","wikidata":"https://www.wikidata.org/wiki/Q766195","display_name":"Protein Data Bank (RCSB PDB)","level":2,"score":0.6590973138809204},{"id":"https://openalex.org/C204328495","wikidata":"https://www.wikidata.org/wiki/Q847556","display_name":"Protein folding","level":2,"score":0.6555218696594238},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5737043023109436},{"id":"https://openalex.org/C10803110","wikidata":"https://www.wikidata.org/wiki/Q1341441","display_name":"Force field (fiction)","level":2,"score":0.565153181552887},{"id":"https://openalex.org/C2775962898","wikidata":"https://www.wikidata.org/wiki/Q5073152","display_name":"Chaperone (clinical)","level":2,"score":0.5628089904785156},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5446748733520508},{"id":"https://openalex.org/C2781442258","wikidata":"https://www.wikidata.org/wiki/Q46310","display_name":"Ab initio","level":2,"score":0.5399096012115479},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.4455931484699249},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.433879554271698},{"id":"https://openalex.org/C18051474","wikidata":"https://www.wikidata.org/wiki/Q899656","display_name":"Protein structure prediction","level":3,"score":0.4233027398586273},{"id":"https://openalex.org/C49853544","wikidata":"https://www.wikidata.org/wiki/Q206229","display_name":"Biomolecule","level":2,"score":0.41595518589019775},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.4016708731651306},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.34084784984588623},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.22129642963409424},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13665011525154114},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.13365629315376282},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07434126734733582},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018832","descriptor_name":"Molecular Chaperones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018832","descriptor_name":"Molecular Chaperones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018832","descriptor_name":"Molecular Chaperones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018832","descriptor_name":"Molecular Chaperones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D050956","descriptor_name":"HSP40 Heat-Shock Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050956","descriptor_name":"HSP40 Heat-Shock Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050956","descriptor_name":"HSP40 Heat-Shock Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050956","descriptor_name":"HSP40 Heat-Shock Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12859-023-05545-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05545-0","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05545-0","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:37932669","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37932669","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:ruj.uj.edu.pl:item/324492","is_oa":true,"landing_page_url":"https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-023-05545-0","pdf_url":"http://ruj.uj.edu.pl/bitstreams/77a65d65-4f76-49c3-96fc-7e357b855688/download","source":{"id":"https://openalex.org/S4306401249","display_name":"Jagiellonian University Repository (Jagiellonian University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I126596746","host_organization_name":"Jagiellonian University","host_organization_lineage":["https://openalex.org/I126596746"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10629080","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10629080","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10629080/pdf/12859_2023_Article_5545.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:2ab79520be1b4674b4807dda6bb7003f","is_oa":true,"landing_page_url":"https://doaj.org/article/2ab79520be1b4674b4807dda6bb7003f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 24, Iss 1, Pp 1-24 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12859-023-05545-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05545-0","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05545-0","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5400000214576721,"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation"}],"awards":[{"id":"https://openalex.org/G4433560962","display_name":"Centre for New Methods in Computational Diagnostics and Personalised Therapy","funder_award_id":"857533","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320310970","display_name":"Uniwersytet Jagiello\u0144ski Collegium Medicum","ror":"https://ror.org/03bqmcz70"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321042","display_name":"Fundacja na rzecz Nauki Polskiej","ror":"https://ror.org/048zd9m77"},{"id":"https://openalex.org/F4320335322","display_name":"European Regional Development Fund","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4388441919.pdf"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W36911157","https://openalex.org/W1964184380","https://openalex.org/W1965555277","https://openalex.org/W1972121275","https://openalex.org/W1979761607","https://openalex.org/W1991527687","https://openalex.org/W2023441054","https://openalex.org/W2029667189","https://openalex.org/W2036282798","https://openalex.org/W2044770225","https://openalex.org/W2052816884","https://openalex.org/W2059968353","https://openalex.org/W2062918974","https://openalex.org/W2065504621","https://openalex.org/W2071210274","https://openalex.org/W2082825744","https://openalex.org/W2114441129","https://openalex.org/W2141398603","https://openalex.org/W2156954132","https://openalex.org/W2163570079","https://openalex.org/W2167924958","https://openalex.org/W2266488717","https://openalex.org/W2282801158","https://openalex.org/W2463412817","https://openalex.org/W2533198818","https://openalex.org/W2766157496","https://openalex.org/W2973305114","https://openalex.org/W2989803368","https://openalex.org/W3016997587","https://openalex.org/W3038166161","https://openalex.org/W3092934522","https://openalex.org/W3106745904","https://openalex.org/W3127884681","https://openalex.org/W3128489930","https://openalex.org/W3130590883","https://openalex.org/W3137896450","https://openalex.org/W3156708429","https://openalex.org/W3191069735","https://openalex.org/W3203003615","https://openalex.org/W3203475177","https://openalex.org/W3204479471","https://openalex.org/W3213924013","https://openalex.org/W4206477719","https://openalex.org/W4210877706","https://openalex.org/W4220696290","https://openalex.org/W4223655903","https://openalex.org/W4280496201","https://openalex.org/W4281617715","https://openalex.org/W4281906817","https://openalex.org/W4285091514","https://openalex.org/W4285385686","https://openalex.org/W4285490835","https://openalex.org/W4311441283","https://openalex.org/W4311781270","https://openalex.org/W4312032124","https://openalex.org/W4313446499","https://openalex.org/W4313891356","https://openalex.org/W4321482809","https://openalex.org/W4378195110","https://openalex.org/W4378575794","https://openalex.org/W4379769521","https://openalex.org/W4385301992","https://openalex.org/W4386767968","https://openalex.org/W4393198850"],"related_works":["https://openalex.org/W2366986171","https://openalex.org/W4239727325","https://openalex.org/W1952548524","https://openalex.org/W2018641097","https://openalex.org/W1603717990","https://openalex.org/W2566200359","https://openalex.org/W4387709260","https://openalex.org/W2072744250","https://openalex.org/W2058658547","https://openalex.org/W2167924958"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,59,102,120,157,190,205],"aqueous":[2],"environment":[3],"directs":[4],"the":[5,10,18,24,28,34,65,82,126,137,140,145,148,175,194,202,221,224],"protein":[6,85,217],"folding":[7,86,127,203,225],"process":[8,83],"towards":[9],"generation":[11],"of":[12,20,30,49,67,73,84,97,122,125,136,142,152,177],"micelle-type":[13],"structures,":[14],"which":[15],"results":[16],"in":[17,33,93,110,162,169,182,214],"exposure":[19],"hydrophilic":[21],"residues":[22,32],"on":[23],"surface":[25],"(polarity)":[26],"and":[27,147],"concentration":[29],"hydrophobic":[31,43,99],"center":[35],"(hydrophobic":[36],"core).":[37],"Obtaining":[38],"a":[39,42,46,57,94,98,133,187],"structure":[40,95,151,218],"without":[41],"core":[44],"requires":[45],"different":[47],"type":[48],"external":[50,179,195,208],"force":[51,180,196,209],"field":[52,197,210],"than":[53],"those":[54],"generated":[55],"by":[56,90,199],"water.":[58],"examples":[60],"are":[61],"membrane":[62],"proteins,":[63],"where":[64],"distribution":[66],"hydrophobicity":[68],"is":[69],"opposite":[70],"to":[71],"that":[72],"water-soluble":[74],"proteins.":[75],"Apart":[76],"from":[77,186],"these":[78],"two":[79],"extreme":[80],"examples,":[81],"can":[87,211],"be":[88,212],"directed":[89],"chaperones,":[91],"resulting":[92],"devoid":[96],"core.":[100],"RESULTS:":[101],"current":[103],"work":[104],"presents":[105],"such":[106],"example:":[107],"DnaJ":[108],"Hsp40":[109],"complex":[111],"with":[112,144],"alkaline":[113],"phosphatase":[114,129],"PhoA-U":[115],"(PDB":[116,130],"ID-6PSI)-the":[117],"client":[118],"molecule.":[119],"availability":[121],"WT":[123],"form":[124],"protein-alkaline":[128],"ID-1EW8)":[131],"enables":[132],"comparative":[134],"analysis":[135],"structures:":[138],"at":[139],"stage":[141],"interaction":[143],"chaperone":[146],"final,":[149],"folded":[150],"this":[153,170,183],"biologically":[154],"active":[155],"protein.":[156],"fuzzy":[158],"oil":[159],"drop":[160],"model":[161,192],"its":[163],"modified":[164],"FOD-M":[165,191],"version":[166],"was":[167],"used":[168],"analysis,":[171],"taking":[172],"into":[173],"account":[174],"influence":[176],"an":[178],"field,":[181],"case":[184],"coming":[185],"chaperone.":[188],"CONCLUSIONS:":[189],"identifies":[193],"introduced":[198],"chaperon":[200],"influencing":[201],"proces.":[204,226],"identified":[206],"specific":[207],"applied":[213],"Ab":[215],"Initio":[216],"prediction":[219],"as":[220],"environmental":[222],"conditioning":[223]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5}],"updated_date":"2026-06-22T08:00:12.763002","created_date":"2025-10-10T00:00:00"}