{"id":"https://openalex.org/W4386929478","doi":"https://doi.org/10.1186/s12859-023-05472-0","title":"KidneyGPS: a user-friendly web application to help prioritize kidney function genes and variants based on evidence from genome-wide association studies","display_name":"KidneyGPS: a user-friendly web application to help prioritize kidney function genes and variants based on evidence from genome-wide association studies","publication_year":2023,"publication_date":"2023-09-21","ids":{"openalex":"https://openalex.org/W4386929478","doi":"https://doi.org/10.1186/s12859-023-05472-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/37735349"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-023-05472-0","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1186/s12859-023-05472-0","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12859-023-05472-0.pdf","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s12859-023-05472-0.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085759325","display_name":"Kira J. Stanzick","orcid":"https://orcid.org/0000-0001-6427-5212"},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kira J. Stanzick","raw_affiliation_strings":["Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany","institution_ids":["https://openalex.org/I60668342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067383632","display_name":"Klaus Stark","orcid":"https://orcid.org/0000-0002-7832-1942"},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Klaus J. Stark","raw_affiliation_strings":["Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany","institution_ids":["https://openalex.org/I60668342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109318645","display_name":"Mathias Gorski","orcid":null},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Mathias Gorski","raw_affiliation_strings":["Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany","institution_ids":["https://openalex.org/I60668342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044656788","display_name":"Johannes Sch\u00f6del","orcid":"https://orcid.org/0000-0002-3587-8839"},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]},{"id":"https://openalex.org/I4210088053","display_name":"Universit\u00e4tsklinikum Erlangen","ror":"https://ror.org/0030f2a11","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210088053"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Johannes Sch\u00f6del","raw_affiliation_strings":["Department of Nephrology and Hypertension, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, and Uniklinikum Erlangen, Erlangen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Hypertension, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, and Uniklinikum Erlangen, Erlangen, Germany","institution_ids":["https://openalex.org/I4210088053","https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076993268","display_name":"Ren\u00e9 Kr\u00fcger","orcid":"https://orcid.org/0000-0003-3731-0224"},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]},{"id":"https://openalex.org/I4210088053","display_name":"Universit\u00e4tsklinikum Erlangen","ror":"https://ror.org/0030f2a11","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210088053"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ren\u00e9 Kr\u00fcger","raw_affiliation_strings":["Department of Nephrology and Hypertension, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, and Uniklinikum Erlangen, Erlangen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Hypertension, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, and Uniklinikum Erlangen, Erlangen, Germany","institution_ids":["https://openalex.org/I4210088053","https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082464365","display_name":"Florian Kronenberg","orcid":"https://orcid.org/0000-0003-2229-1120"},"institutions":[{"id":"https://openalex.org/I143397708","display_name":"Innsbruck Medical University","ror":"https://ror.org/03pt86f80","country_code":"AT","type":"education","lineage":["https://openalex.org/I143397708"]},{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Florian Kronenberg","raw_affiliation_strings":["Department of Genetics, Institute of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Institute of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria","institution_ids":["https://openalex.org/I143397708","https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006230926","display_name":"Richard Warth","orcid":"https://orcid.org/0000-0001-6084-0659"},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Richard Warth","raw_affiliation_strings":["Medical Cell Biology, University of Regensburg, Regensburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Cell Biology, University of Regensburg, Regensburg, Germany","institution_ids":["https://openalex.org/I60668342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074235125","display_name":"Iris M. Heid","orcid":"https://orcid.org/0000-0002-4122-5308"},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Iris M. Heid","raw_affiliation_strings":["Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany. iris.heid@ukr.de","Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany. iris.heid@ukr.de","institution_ids":["https://openalex.org/I60668342"]},{"raw_affiliation_string":"Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany","institution_ids":["https://openalex.org/I60668342"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013037783","display_name":"Thomas W. Winkler","orcid":"https://orcid.org/0000-0003-0292-5421"},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Thomas W. Winkler","raw_affiliation_strings":["Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany. thomas.winkler@ukr.de","Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany. thomas.winkler@ukr.de","institution_ids":["https://openalex.org/I60668342"]},{"raw_affiliation_string":"Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany","institution_ids":["https://openalex.org/I60668342"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5013037783","https://openalex.org/A5074235125"],"corresponding_institution_ids":["https://openalex.org/I60668342"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1889,"currency":"EUR","value_usd":2037},"fwci":1.1722,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.77857598,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"24","issue":"1","first_page":"355","last_page":"355"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.5789999961853027,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.5789999961853027,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.32710000872612,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.03999999910593033,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5484576225280762},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.5405480265617371},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.5211129784584045},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.5195274949073792},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5175501704216003},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.48689380288124084},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"Genome-wide association study","score":0.429280549287796},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3952246904373169},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.38701388239860535},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.36735183000564575},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.34974852204322815},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.16619616746902466},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.10057434439659119},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.08084267377853394}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5484576225280762},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.5405480265617371},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5211129784584045},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5195274949073792},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5175501704216003},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48689380288124084},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.429280549287796},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3952246904373169},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.38701388239860535},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.36735183000564575},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34974852204322815},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.16619616746902466},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.10057434439659119},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.08084267377853394}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1186/s12859-023-05472-0","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1186/s12859-023-05472-0","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12859-023-05472-0.pdf","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:37735349","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37735349","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:epub.uni-regensburg.de:54751","is_oa":true,"landing_page_url":"http://orcid.org/0000-0001-6427-5212>,","pdf_url":"https://epub.uni-regensburg.de/54751/1/s12859-023-05472-0-1.pdf","source":{"id":"https://openalex.org/S4306401229","display_name":"University of Regensburg Publication Server (University of Regensburg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I60668342","host_organization_name":"University of Regensburg","host_organization_lineage":["https://openalex.org/I60668342"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10512588","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10512588","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10512588/pdf/12859_2023_Article_5472.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:144f4c890af4425ca63440a83d0e7947","is_oa":true,"landing_page_url":"https://doaj.org/article/144f4c890af4425ca63440a83d0e7947","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 24, Iss 1, Pp 1-12 (2023)","raw_type":"article"},{"id":"doi:10.5283/epub.54751","is_oa":true,"landing_page_url":"https://doi.org/10.5283/epub.54751","pdf_url":null,"source":{"id":"https://openalex.org/S4306401229","display_name":"University of Regensburg Publication Server (University of Regensburg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I60668342","host_organization_name":"University of Regensburg","host_organization_lineage":["https://openalex.org/I60668342"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.5283/epub.55162","is_oa":true,"landing_page_url":"https://doi.org/10.5283/epub.55162","pdf_url":null,"source":{"id":"https://openalex.org/S4306401229","display_name":"University of Regensburg Publication Server (University of Regensburg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I60668342","host_organization_name":"University of Regensburg","host_organization_lineage":["https://openalex.org/I60668342"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1186/s12859-023-05472-0","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1186/s12859-023-05472-0","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12859-023-05472-0.pdf","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3820224712","display_name":null,"funder_award_id":"TRR 374","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3831163817","display_name":"SFB 1350: Tubulussystem und Interstitium der Niere: (Patho)Physiologie und Crosstalk","funder_award_id":"387509280","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G5218963530","display_name":null,"funder_award_id":"387509280, SFB 1350","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G534687194","display_name":"TRR 374: Tubulussystem und Interstitium der Niere: (Patho)Physiologie und Crosstalk","funder_award_id":"509149993","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G6396867879","display_name":null,"funder_award_id":"Project-ID 509149993","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G7372259530","display_name":null,"funder_award_id":"Project-ID 509149993, TRR 374","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G8855989013","display_name":null,"funder_award_id":"SFB 1350","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320323215","display_name":"Universit\u00e4tsklinikum Regensburg","ror":"https://ror.org/01226dv09"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386929478.pdf","grobid_xml":"https://content.openalex.org/works/W4386929478.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1994127362","https://openalex.org/W2002359955","https://openalex.org/W2152885121","https://openalex.org/W2155449815","https://openalex.org/W2163013660","https://openalex.org/W2233221674","https://openalex.org/W2297334215","https://openalex.org/W2417483443","https://openalex.org/W2753051611","https://openalex.org/W2761275051","https://openalex.org/W2806225217","https://openalex.org/W2894662039","https://openalex.org/W2900255713","https://openalex.org/W2905452503","https://openalex.org/W2906428833","https://openalex.org/W2947278243","https://openalex.org/W2952295900","https://openalex.org/W2995245946","https://openalex.org/W3042068575","https://openalex.org/W3092119378","https://openalex.org/W3100917749","https://openalex.org/W3182222456","https://openalex.org/W3192811676","https://openalex.org/W3210331473","https://openalex.org/W4281572263","https://openalex.org/W4282542011","https://openalex.org/W4282961980","https://openalex.org/W4282973468","https://openalex.org/W4286218496","https://openalex.org/W4308174398","https://openalex.org/W4308616307"],"related_works":["https://openalex.org/W1864400744","https://openalex.org/W4390666975","https://openalex.org/W3209211130","https://openalex.org/W2736520836","https://openalex.org/W3093265873","https://openalex.org/W2971313479","https://openalex.org/W1966248182","https://openalex.org/W2116256947","https://openalex.org/W2128541119","https://openalex.org/W2588359518"],"abstract_inverted_index":{"BACKGROUND:":[0],"Genome-wide":[1],"association":[2,28,113],"studies":[3],"(GWAS)":[4],"have":[5],"identified":[6,176],"hundreds":[7],"of":[8,41,129,153,187,198,218,284,317],"genetic":[9,111,131,262],"loci":[10,173,242],"associated":[11],"with":[12,19,127,133,142,220,243,266,268,275],"kidney":[13,95,143,246,295,319,329],"function.":[14],"By":[15],"combining":[16],"these":[17],"findings":[18],"post-GWAS":[20,79,311],"information":[21,199],"(e.g.,":[22],"statistical":[23,270],"fine-mapping":[24],"to":[25,31,35,57,65,94,195,215,261,281,331],"identify":[26,66],"independent":[27,189],"signals":[29,34,265],"and":[30,48,78,84,150,178,206,310,313],"narrow":[32],"down":[33],"causal":[36],"variants;":[37],"or":[38,135,147,250,252,264,341],"different":[39],"sources":[40],"annotation":[42,128],"data),":[43],"new":[44,67],"hypotheses":[45,55],"regarding":[46],"physiology":[47],"disease":[49],"aetiology":[50],"can":[51,232,254],"be":[52,58,82,233,255],"obtained.":[53],"These":[54,229],"need":[56],"tested":[59],"in":[60,86,145,169,182,239,248,277,334,339,342],"laboratory":[61],"experiments,":[62],"for":[63,114,165,174,203,307,328],"example,":[64],"therapeutic":[68],"targets.":[69],"For":[70],"this":[71],"purpose,":[72],"the":[73,121,170,179,183,196,240,292,314,318],"evidence":[74,164],"obtained":[75],"from":[76,120],"GWAS":[77,99,172,309],"analyses":[80],"must":[81],"processed":[83],"presented":[85],"a":[87,106,160,211,244,278,301],"way":[88],"that":[89,109],"they":[90,253],"are":[91],"easily":[92],"accessible":[93],"researchers":[96,330],"without":[97],"specific":[98,221,230,315],"expertise.":[100],"MAIN:":[101],"Here":[102],"we":[103],"present":[104],"KidneyGPS,":[105],"user-friendly":[107,193],"web-application":[108],"combines":[110],"variant":[112],"estimated":[115],"glomerular":[116],"filtration":[117],"rate":[118],"(eGFR)":[119],"Chronic":[122],"Kidney":[123],"Disease":[124],"Genetics":[125],"consortium":[126],"(i)":[130],"variants":[132,181,263],"functional":[134],"regulatory":[136],"effects":[137],"(\"SNP-to-gene\"":[138],"mapping),":[139],"(ii)":[140],"genes":[141,154,168,219,259],"phenotypes":[144],"mice":[146,249],"human":[148],"(\"gene-to-phenotype\"),":[149],"(iii)":[151],"drugability":[152],"(to":[155],"support":[156],"re-purposing).":[157],"KidneyGPS":[158,191,208,272,299,324],"adopts":[159],"comprehensive":[161],"approach":[162],"summarizing":[163],"all":[166],"5906":[167],"424":[171,241],"eGFR":[175],"previously":[177],"35,885":[180],"99%":[184],"credible":[185],"sets":[186],"594":[188],"signals.":[190],"enables":[192],"access":[194],"abundance":[197],"by":[200],"search":[201],"functions":[202],"genes,":[204],"variants,":[205],"regions.":[207],"also":[209],"provides":[210],"function":[212,296],"(\"GPS":[213],"tab\")":[214],"generate":[216],"lists":[217],"characteristics":[222,231],"thus":[223],"enabling":[224],"customizable":[225],"Gene":[226],"Prioritisation":[227],"(GPS).":[228],"as":[234,236],"broad":[235],"any":[237],"gene":[238],"known":[245],"phenotype":[247],"human;":[251],"highly":[256],"focussed":[257],"on":[258,294],"mapping":[260],"particularly":[267],"high":[269],"support.":[271],"is":[273],"implemented":[274],"RShiny":[276],"modularized":[279],"fashion":[280],"facilitate":[282],"update":[283],"input":[285],"data":[286],"(":[287],"https://kidneygps.ur.de/gps/":[288],").":[289],"CONCLUSION:":[290],"With":[291],"focus":[293],"related":[297],"evidence,":[298],"fills":[300],"gap":[302],"between":[303],"large":[304],"general":[305],"platforms":[306],"accessing":[308],"results":[312,337],"needs":[316],"research":[320,336],"community.":[321],"This":[322],"makes":[323],"an":[325],"important":[326],"platform":[327],"help":[332],"translate":[333],"silico":[335],"into":[338],"vitro":[340],"vivo":[343],"research.":[344]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-07-02T09:51:11.867554","created_date":"2025-10-10T00:00:00"}