{"id":"https://openalex.org/W4386254278","doi":"https://doi.org/10.1186/s12859-023-05451-5","title":"A knowledge graph approach to predict and interpret disease-causing gene interactions","display_name":"A knowledge graph approach to predict and interpret disease-causing gene interactions","publication_year":2023,"publication_date":"2023-08-29","ids":{"openalex":"https://openalex.org/W4386254278","doi":"https://doi.org/10.1186/s12859-023-05451-5","pmid":"https://pubmed.ncbi.nlm.nih.gov/37644440"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-023-05451-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05451-5","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05451-5","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05451-5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081793262","display_name":"Alexandre Renaux","orcid":"https://orcid.org/0000-0002-4339-2791"},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]},{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Alexandre Renaux","raw_affiliation_strings":["Artificial Intelligence lab, Vrije Universiteit Brussel, Brussels, Belgium. Alexandre.Renaux@ulb.be","Interuniversity Institute of Bioinformatics in Brussels, Universit\u00e9 Libre de Bruxelles - Vrije Universiteit Brussel, Brussels, Belgium. Alexandre.Renaux@ulb.be","Machine Learning Group, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium. Alexandre.Renaux@ulb.be","Interuniversity Institute of Bioinformatics in Brussels, Universit\u00e9 Libre de Bruxelles - Vrije Universiteit Brussel, Brussels, Belgium"],"affiliations":[{"raw_affiliation_string":"Artificial Intelligence lab, Vrije Universiteit Brussel, Brussels, Belgium. Alexandre.Renaux@ulb.be","institution_ids":[]},{"raw_affiliation_string":"Interuniversity Institute of Bioinformatics in Brussels, Universit\u00e9 Libre de Bruxelles - Vrije Universiteit Brussel, Brussels, Belgium. Alexandre.Renaux@ulb.be","institution_ids":[]},{"raw_affiliation_string":"Machine Learning Group, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium. Alexandre.Renaux@ulb.be","institution_ids":[]},{"raw_affiliation_string":"Interuniversity Institute of Bioinformatics in Brussels, Universit\u00e9 Libre de Bruxelles - Vrije Universiteit Brussel, Brussels, Belgium","institution_ids":["https://openalex.org/I132053463","https://openalex.org/I13469542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092139588","display_name":"Chlo\u00e9 Terwagne","orcid":"https://orcid.org/0000-0002-1208-2707"},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]},{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Chlo\u00e9 Terwagne","raw_affiliation_strings":["Interuniversity Institute of Bioinformatics in Brussels, Universit\u00e9 Libre de Bruxelles - Vrije Universiteit Brussel, Brussels, Belgium","Machine Learning Group, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium"],"affiliations":[{"raw_affiliation_string":"Interuniversity Institute of Bioinformatics in Brussels, Universit\u00e9 Libre de Bruxelles - Vrije Universiteit Brussel, Brussels, Belgium","institution_ids":["https://openalex.org/I132053463","https://openalex.org/I13469542"]},{"raw_affiliation_string":"Machine Learning Group, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium","institution_ids":["https://openalex.org/I132053463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041317183","display_name":"Michael Cochez","orcid":"https://orcid.org/0000-0001-5726-4638"},"institutions":[{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]},{"id":"https://openalex.org/I1318003438","display_name":"RELX Group (Netherlands)","ror":"https://ror.org/02scfj030","country_code":"NL","type":"company","lineage":["https://openalex.org/I1318003438","https://openalex.org/I4210160603"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Michael Cochez","raw_affiliation_strings":["Computer Science, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands","Discovery Lab, Elsevier, Amsterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Computer Science, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I865915315"]},{"raw_affiliation_string":"Discovery Lab, Elsevier, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I1318003438"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075467369","display_name":"Ilaria Tiddi","orcid":"https://orcid.org/0000-0001-7116-9338"},"institutions":[{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Ilaria Tiddi","raw_affiliation_strings":["Computer Science, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Computer Science, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064553018","display_name":"Ann Now\u00e9","orcid":"https://orcid.org/0000-0001-6346-4564"},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]},{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Ann Now\u00e9","raw_affiliation_strings":["Artificial Intelligence lab, Vrije Universiteit Brussel, Brussels, Belgium","Interuniversity Institute of Bioinformatics in Brussels, Universit\u00e9 Libre de Bruxelles - Vrije Universiteit Brussel, Brussels, Belgium"],"affiliations":[{"raw_affiliation_string":"Artificial Intelligence lab, Vrije Universiteit Brussel, Brussels, Belgium","institution_ids":["https://openalex.org/I13469542"]},{"raw_affiliation_string":"Interuniversity Institute of Bioinformatics in Brussels, Universit\u00e9 Libre de Bruxelles - Vrije Universiteit Brussel, Brussels, Belgium","institution_ids":["https://openalex.org/I132053463","https://openalex.org/I13469542"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003581663","display_name":"Tom Lenaerts","orcid":"https://orcid.org/0000-0003-3645-1455"},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Tom Lenaerts","raw_affiliation_strings":["Artificial Intelligence lab, Vrije Universiteit Brussel, Brussels, Belgium. tom.lenaerts@ulb.be","Interuniversity Institute of Bioinformatics in Brussels, Universit\u00e9 Libre de Bruxelles - Vrije Universiteit Brussel, Brussels, Belgium. tom.lenaerts@ulb.be","Machine Learning Group, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium. tom.lenaerts@ulb.be","Machine Learning Group, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium"],"affiliations":[{"raw_affiliation_string":"Artificial Intelligence lab, Vrije Universiteit Brussel, Brussels, Belgium. tom.lenaerts@ulb.be","institution_ids":[]},{"raw_affiliation_string":"Interuniversity Institute of Bioinformatics in Brussels, Universit\u00e9 Libre de Bruxelles - Vrije Universiteit Brussel, Brussels, Belgium. tom.lenaerts@ulb.be","institution_ids":[]},{"raw_affiliation_string":"Machine Learning Group, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium. tom.lenaerts@ulb.be","institution_ids":[]},{"raw_affiliation_string":"Machine Learning Group, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium","institution_ids":["https://openalex.org/I132053463"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5081793262"],"corresponding_institution_ids":["https://openalex.org/I132053463","https://openalex.org/I13469542"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":3.9497,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.94160474,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"24","issue":"1","first_page":"324","last_page":"324"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9890000224113464,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interpretability","display_name":"Interpretability","score":0.9376734495162964},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5545654296875},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.489734411239624},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.4791404902935028},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.47400152683258057},{"id":"https://openalex.org/keywords/trait","display_name":"Trait","score":0.4589499235153198},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.4330664277076721},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.414242684841156},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4095413088798523},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3598639965057373},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.33365461230278015},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.29026874899864197},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.23554342985153198},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.21600154042243958},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.18248510360717773},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.08916929364204407},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.08821350336074829}],"concepts":[{"id":"https://openalex.org/C2781067378","wikidata":"https://www.wikidata.org/wiki/Q17027399","display_name":"Interpretability","level":2,"score":0.9376734495162964},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5545654296875},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.489734411239624},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.4791404902935028},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.47400152683258057},{"id":"https://openalex.org/C106934330","wikidata":"https://www.wikidata.org/wiki/Q1971873","display_name":"Trait","level":2,"score":0.4589499235153198},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.4330664277076721},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.414242684841156},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4095413088798523},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3598639965057373},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.33365461230278015},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.29026874899864197},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23554342985153198},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.21600154042243958},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18248510360717773},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.08916929364204407},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.08821350336074829},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004843","descriptor_name":"Epistasis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004843","descriptor_name":"Epistasis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004843","descriptor_name":"Epistasis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1186/s12859-023-05451-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05451-5","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05451-5","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:37644440","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37644440","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:research.vu.nl:openaire_cris_publications/8c61e5df-6a8e-4c14-868a-1a1d10565728","is_oa":true,"landing_page_url":"https://research.vu.nl/en/publications/8c61e5df-6a8e-4c14-868a-1a1d10565728","pdf_url":null,"source":{"id":"https://openalex.org/S4306401107","display_name":"VU Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I865915315","host_organization_name":"Vrije Universiteit Amsterdam","host_organization_lineage":["https://openalex.org/I865915315"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Renaux, A, Terwagne, C, Cochez, M, Tiddi, I, Now\u00e9, A & Lenaerts, T 2023, 'A knowledge graph approach to predict and interpret disease-causing gene interactions', BMC Bioinformatics, vol. 24, 324, pp. 1-25. https://doi.org/10.1186/s12859-023-05451-5","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:dipot.ulb.ac.be:2013/363454","is_oa":true,"landing_page_url":"http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/363454","pdf_url":"https://dipot.ulb.ac.be/dspace/bitstream/2013/363454/1/doi_347098.pdf","source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC bioinformatics, 24 (1","raw_type":"info:ulb-repo/semantics/openurl/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10463539","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10463539","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10463539/pdf/12859_2023_Article_5451.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:168579","is_oa":true,"landing_page_url":"https://biblio.vub.ac.be/vubir/a-knowledge-graph-approach-to-predict-and-interpret-diseasecausing-gene-interactions(137c39a9-02ce-4eb9-a98a-9735ffdfb7a4).html","pdf_url":"https://biblio.vub.ac.be/vubirfiles/105782496/98655842.pdf","source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"publishedVersion"},{"id":"pmh:oai:doaj.org/article:5668891e574e4654b3bf5f277622f097","is_oa":true,"landing_page_url":"https://doaj.org/article/5668891e574e4654b3bf5f277622f097","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 24, Iss 1, Pp 1-25 (2023)","raw_type":"article"},{"id":"pmh:oai:research.vu.nl:openaire/8c61e5df-6a8e-4c14-868a-1a1d10565728","is_oa":true,"landing_page_url":"https://hdl.handle.net/1871.1/8c61e5df-6a8e-4c14-868a-1a1d10565728","pdf_url":null,"source":{"id":"https://openalex.org/S4306401107","display_name":"VU Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I865915315","host_organization_name":"Vrije Universiteit Amsterdam","host_organization_lineage":["https://openalex.org/I865915315"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Renaux, A, Terwagne, C, Cochez, M, Tiddi, I, Now\u00e9, A & Lenaerts, T 2023, 'A knowledge graph approach to predict and interpret disease-causing gene interactions', BMC Bioinformatics, vol. 24, 324, pp. 1-25. https://doi.org/10.1186/s12859-023-05451-5","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1186/s12859-023-05451-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05451-5","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05451-5","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6100000143051147,"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions"}],"awards":[{"id":"https://openalex.org/G1219412175","display_name":null,"funder_award_id":"35276964","funder_id":"https://openalex.org/F4320321390","funder_display_name":"Fonds De La Recherche Scientifique - FNRS"},{"id":"https://openalex.org/G182602407","display_name":null,"funder_award_id":"952215","funder_id":"https://openalex.org/F4320334322","funder_display_name":"HORIZON EUROPE Framework Programme"},{"id":"https://openalex.org/G223064752","display_name":null,"funder_award_id":"27.002.53.01.4524","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G2631452109","display_name":null,"funder_award_id":"(ERDF)","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G2958898274","display_name":null,"funder_award_id":"IRP8b","funder_id":"https://openalex.org/F4320322634","funder_display_name":"Vrije Universiteit Brussel"},{"id":"https://openalex.org/G3635979023","display_name":null,"funder_award_id":"35276964","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G3875748329","display_name":null,"funder_award_id":"European Regional Development Fund","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4103945517","display_name":null,"funder_award_id":"952215","funder_id":"https://openalex.org/F4320335254","funder_display_name":"Horizon 2020"},{"id":"https://openalex.org/G453067482","display_name":null,"funder_award_id":"014-2020","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G4956428346","display_name":null,"funder_award_id":"Horizon 2020 research and innovatio","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4977106383","display_name":null,"funder_award_id":"European Regional Development Fund (ERDF)","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5219130566","display_name":null,"funder_award_id":"EU Horizon","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5564432353","display_name":null,"funder_award_id":"101093202","funder_id":"https://openalex.org/F4320334322","funder_display_name":"HORIZON EUROPE Framework Programme"},{"id":"https://openalex.org/G5634946813","display_name":null,"funder_award_id":"2014-2020","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G6870533126","display_name":null,"funder_award_id":"2014-2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G7507225614","display_name":null,"funder_award_id":"76964","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8079567275","display_name":null,"funder_award_id":"952215","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8318064016","display_name":null,"funder_award_id":"Horizon","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8432427218","display_name":null,"funder_award_id":"2020 RDIR 55b","funder_id":"https://openalex.org/F4320322852","funder_display_name":"Innoviris"},{"id":"https://openalex.org/G8538941428","display_name":null,"funder_award_id":"Regional Development Fund","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8570012161","display_name":null,"funder_award_id":"unknown","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G8594859193","display_name":null,"funder_award_id":"I002819N","funder_id":"https://openalex.org/F4320321730","funder_display_name":"Fonds Wetenschappelijk Onderzoek"},{"id":"https://openalex.org/G8611529892","display_name":null,"funder_award_id":"101093202","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321390","display_name":"Fonds De La Recherche Scientifique - FNRS","ror":"https://ror.org/03q83t159"},{"id":"https://openalex.org/F4320321730","display_name":"Fonds Wetenschappelijk Onderzoek","ror":"https://ror.org/03qtxy027"},{"id":"https://openalex.org/F4320322634","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04"},{"id":"https://openalex.org/F4320322852","display_name":"Innoviris","ror":"https://ror.org/04af9zr29"},{"id":"https://openalex.org/F4320327336","display_name":"Vlaamse regering","ror":null},{"id":"https://openalex.org/F4320334322","display_name":"HORIZON EUROPE Framework Programme","ror":null},{"id":"https://openalex.org/F4320335254","display_name":"Horizon 2020","ror":null},{"id":"https://openalex.org/F4320335322","display_name":"European Regional Development Fund","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4386254278.pdf"},"referenced_works_count":98,"referenced_works":["https://openalex.org/W66185676","https://openalex.org/W103340358","https://openalex.org/W1529607257","https://openalex.org/W1595159159","https://openalex.org/W1642443113","https://openalex.org/W1925054293","https://openalex.org/W1964426200","https://openalex.org/W1968601254","https://openalex.org/W1971192989","https://openalex.org/W1980948656","https://openalex.org/W1986277022","https://openalex.org/W1986818660","https://openalex.org/W1996391793","https://openalex.org/W2005191830","https://openalex.org/W2009609793","https://openalex.org/W2010466873","https://openalex.org/W2017442850","https://openalex.org/W2018554179","https://openalex.org/W2036762380","https://openalex.org/W2047300521","https://openalex.org/W2055043387","https://openalex.org/W2062699991","https://openalex.org/W2063348376","https://openalex.org/W2066531004","https://openalex.org/W2066771339","https://openalex.org/W2091831926","https://openalex.org/W2101220662","https://openalex.org/W2105887574","https://openalex.org/W2118344440","https://openalex.org/W2122264952","https://openalex.org/W2124879534","https://openalex.org/W2128863027","https://openalex.org/W2143602768","https://openalex.org/W2146215535","https://openalex.org/W2148043260","https://openalex.org/W2152565567","https://openalex.org/W2153065499","https://openalex.org/W2153690746","https://openalex.org/W2156194072","https://openalex.org/W2159675211","https://openalex.org/W2160995259","https://openalex.org/W2161468919","https://openalex.org/W2171502901","https://openalex.org/W2187413858","https://openalex.org/W2295128594","https://openalex.org/W2367397349","https://openalex.org/W2554687533","https://openalex.org/W2732446246","https://openalex.org/W2734806099","https://openalex.org/W2762248845","https://openalex.org/W2765910974","https://openalex.org/W2809000676","https://openalex.org/W2848983148","https://openalex.org/W2861293586","https://openalex.org/W2890758473","https://openalex.org/W2891112820","https://openalex.org/W2900569176","https://openalex.org/W2901933496","https://openalex.org/W2905452503","https://openalex.org/W2911161668","https://openalex.org/W2927574259","https://openalex.org/W2937762029","https://openalex.org/W2947236961","https://openalex.org/W2949311246","https://openalex.org/W2949598989","https://openalex.org/W2951531839","https://openalex.org/W2954752112","https://openalex.org/W2966298461","https://openalex.org/W3004052817","https://openalex.org/W3006877085","https://openalex.org/W3010336026","https://openalex.org/W3028442883","https://openalex.org/W3028527629","https://openalex.org/W3030709095","https://openalex.org/W3094967361","https://openalex.org/W3096568637","https://openalex.org/W3106811464","https://openalex.org/W3107322429","https://openalex.org/W3120491054","https://openalex.org/W3133859624","https://openalex.org/W3136918052","https://openalex.org/W3163501683","https://openalex.org/W3186118520","https://openalex.org/W3198262548","https://openalex.org/W3200057886","https://openalex.org/W3210179814","https://openalex.org/W3213797660","https://openalex.org/W3217729113","https://openalex.org/W4205247356","https://openalex.org/W4220768028","https://openalex.org/W4220795099","https://openalex.org/W4221048327","https://openalex.org/W4221106438","https://openalex.org/W4243979784","https://openalex.org/W4295198017","https://openalex.org/W4367600858","https://openalex.org/W6675824659","https://openalex.org/W6887803762"],"related_works":["https://openalex.org/W2905433371","https://openalex.org/W2888392564","https://openalex.org/W4310278675","https://openalex.org/W4388422664","https://openalex.org/W4390569940","https://openalex.org/W4361193272","https://openalex.org/W2963326959","https://openalex.org/W4388685194","https://openalex.org/W4312407344","https://openalex.org/W1986582023"],"abstract_inverted_index":{"Our":[0],"method,":[1],"built":[2],"with":[3],"interpretability":[4],"in":[5,11,45],"mind,":[6],"leverages":[7],"heterogenous":[8],"path":[9],"information":[10],"knowledge":[12,43],"graphs":[13,44],"to":[14],"predict":[15],"pathogenic":[16],"gene":[17],"interactions":[18],"and":[19,49],"generate":[20],"meaningful":[21],"explanations.":[22],"This":[23],"not":[24],"only":[25],"broadens":[26],"our":[27],"understanding":[28],"of":[29,42],"the":[30],"molecular":[31],"mechanisms":[32],"underlying":[33],"oligogenic":[34],"diseases,":[35],"but":[36],"also":[37],"presents":[38],"a":[39],"novel":[40],"application":[41],"creating":[46],"more":[47],"transparent":[48],"insightful":[50],"predictors":[51],"for":[52],"genetic":[53],"research.":[54]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":3}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}