{"id":"https://openalex.org/W4367054755","doi":"https://doi.org/10.1186/s12859-023-05272-6","title":"meth-SemiCancer: a cancer subtype classification framework via semi-supervised learning utilizing DNA methylation profiles","display_name":"meth-SemiCancer: a cancer subtype classification framework via semi-supervised learning utilizing DNA methylation profiles","publication_year":2023,"publication_date":"2023-04-26","ids":{"openalex":"https://openalex.org/W4367054755","doi":"https://doi.org/10.1186/s12859-023-05272-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/37101254"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-023-05272-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05272-6","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05272-6","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05272-6","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080551816","display_name":"Joung Min Choi","orcid":"https://orcid.org/0000-0003-2090-3330"},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joung Min Choi","raw_affiliation_strings":["Department of Computer Science, Virginia Tech, Blacksburg, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Virginia Tech, Blacksburg, USA","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087993682","display_name":"Chaelin Park","orcid":"https://orcid.org/0009-0001-0731-7057"},"institutions":[{"id":"https://openalex.org/I31766871","display_name":"Sookmyung Women's University","ror":"https://ror.org/00vvvt117","country_code":"KR","type":"education","lineage":["https://openalex.org/I31766871"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chaelin Park","raw_affiliation_strings":["Division of Computer Science, Sookmyung Women's University, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Computer Science, Sookmyung Women's University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I31766871"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101608081","display_name":"Heejoon Chae","orcid":"https://orcid.org/0000-0002-0960-5829"},"institutions":[{"id":"https://openalex.org/I31766871","display_name":"Sookmyung Women's University","ror":"https://ror.org/00vvvt117","country_code":"KR","type":"education","lineage":["https://openalex.org/I31766871"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Heejoon Chae","raw_affiliation_strings":["Division of Computer Science, Sookmyung Women's University, Seoul, Republic of Korea. heechae@sookmyung.ac.kr","Division of Computer Science, Sookmyung Women's University, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Computer Science, Sookmyung Women's University, Seoul, Republic of Korea. heechae@sookmyung.ac.kr","institution_ids":["https://openalex.org/I31766871"]},{"raw_affiliation_string":"Division of Computer Science, Sookmyung Women's University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I31766871"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101608081"],"corresponding_institution_ids":["https://openalex.org/I31766871"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":1.0116,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.73602757,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"24","issue":"1","first_page":"168","last_page":"168"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.4284000098705292,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.4284000098705292,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.13189999759197235,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.13009999692440033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.7095199823379517},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.5696221590042114},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5568959712982178},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"Carcinogenesis","score":0.5160860419273376},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5016970634460449},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.48935621976852417},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.4711548089981079},{"id":"https://openalex.org/keywords/methylation","display_name":"Methylation","score":0.43637996912002563},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3915693163871765},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3443683087825775},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.3141387104988098},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.15596914291381836},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1276770532131195},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.09307125210762024}],"concepts":[{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.7095199823379517},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.5696221590042114},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5568959712982178},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.5160860419273376},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5016970634460449},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.48935621976852417},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4711548089981079},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.43637996912002563},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3915693163871765},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3443683087825775},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.3141387104988098},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15596914291381836},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1276770532131195},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.09307125210762024}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069553","descriptor_name":"Supervised Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069553","descriptor_name":"Supervised Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069553","descriptor_name":"Supervised Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12859-023-05272-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05272-6","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05272-6","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:37101254","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37101254","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":"Journal Article"},{"id":"pmh:oai:vtechworks.lib.vt.edu:10919/114858","is_oa":true,"landing_page_url":"http://hdl.handle.net/10919/114858","pdf_url":"https://vtechworks.lib.vt.edu/bitstreams/488c2464-2b78-41f9-87f8-eb283c362d68/download","source":{"id":"https://openalex.org/S4306400248","display_name":"VTechWorks (Virginia Tech)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I859038795","host_organization_name":"Virginia Tech","host_organization_lineage":["https://openalex.org/I859038795"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article - Refereed"},{"id":"pmh:oai:pubmedcentral.nih.gov:10131478","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10131478","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10131478/pdf/12859_2023_Article_5272.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:b9e75bc63a9049219de036c2700bc7ed","is_oa":true,"landing_page_url":"https://doaj.org/article/b9e75bc63a9049219de036c2700bc7ed","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 24, Iss 1, Pp 1-14 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12859-023-05272-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-023-05272-6","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-023-05272-6","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1985140077","display_name":null,"funder_award_id":"2021R1F1A1050707","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G3030330391","display_name":null,"funder_award_id":"2019M3E5D3073365","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G7152094987","display_name":null,"funder_award_id":"2019M3E5D3073365","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G7161383449","display_name":null,"funder_award_id":"2019M3E5D3073365","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"}],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"},{"id":"https://openalex.org/F4320328359","display_name":"Ministry of Science and ICT, South Korea","ror":"https://ror.org/01wpjm123"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4367054755.pdf","grobid_xml":"https://content.openalex.org/works/W4367054755.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W179179905","https://openalex.org/W1596717185","https://openalex.org/W1848939527","https://openalex.org/W1934094702","https://openalex.org/W1973767578","https://openalex.org/W1981276685","https://openalex.org/W1983320747","https://openalex.org/W1985444222","https://openalex.org/W2001502878","https://openalex.org/W2020541351","https://openalex.org/W2034594496","https://openalex.org/W2103474120","https://openalex.org/W2106096365","https://openalex.org/W2125283600","https://openalex.org/W2132619562","https://openalex.org/W2147944526","https://openalex.org/W2150777859","https://openalex.org/W2157840751","https://openalex.org/W2158485828","https://openalex.org/W2161112598","https://openalex.org/W2263206910","https://openalex.org/W2288944226","https://openalex.org/W2309067861","https://openalex.org/W2409748667","https://openalex.org/W2943865428","https://openalex.org/W2957423565","https://openalex.org/W2968856704","https://openalex.org/W2980183989","https://openalex.org/W2999309192","https://openalex.org/W3012566059","https://openalex.org/W3020424172","https://openalex.org/W3027953580","https://openalex.org/W3093900604","https://openalex.org/W3130668074","https://openalex.org/W3176749558","https://openalex.org/W4200173448","https://openalex.org/W4280630188","https://openalex.org/W6610017368","https://openalex.org/W6632604870","https://openalex.org/W6732629455"],"related_works":["https://openalex.org/W1455488868","https://openalex.org/W2902329290","https://openalex.org/W2052355316","https://openalex.org/W2046964473","https://openalex.org/W2107880877","https://openalex.org/W2151182744","https://openalex.org/W2024490794","https://openalex.org/W2221018455","https://openalex.org/W2054863651","https://openalex.org/W1998349112"],"abstract_inverted_index":{"BACKGROUND:":[0],"Identification":[1],"of":[2,23,34,68],"the":[3,20,35,44,49,61,65,74,119,123,131,134,142,151,158,162,169,181,184,190,199],"cancer":[4,55,71,81,102,124,135],"subtype":[5,75,82,103,125,138,203],"plays":[6],"a":[7,80,100],"crucial":[8],"role":[9],"to":[10,18,51,60,78,195],"provide":[11],"an":[12],"accurate":[13],"diagnosis":[14],"and":[15,40,64,153,173],"proper":[16,191],"treatment":[17],"improve":[19],"clinical":[21],"outcomes":[22],"patients.":[24],"Recent":[25],"studies":[26],"have":[27,48],"shown":[28],"that":[29],"DNA":[30,45,69,86,108],"methylation":[31,46,109,120],"is":[32,207],"one":[33],"key":[36],"factors":[37],"for":[38,133],"tumorigenesis":[39],"tumor":[41],"growth,":[42],"where":[43],"signatures":[47],"potential":[50],"be":[52],"utilized":[53],"as":[54],"subtype-specific":[56],"markers.":[57],"However,":[58],"due":[59],"high":[62],"dimensionality":[63],"low":[66],"number":[67],"methylome":[70,87],"samples":[72,187],"with":[73,122,161,183],"information,":[76],"still,":[77],"date,":[79],"classification":[83,104,204],"method":[84],"utilizing":[85,149],"datasets":[88,121,136],"has":[89],"not":[90],"been":[91],"proposed.":[92],"RESULTS:":[93],"In":[94],"this":[95],"paper,":[96],"we":[97],"present":[98],"meth-SemiCancer,":[99],"semi-supervised":[101],"framework":[105],"based":[106,117,140],"on":[107,118,141],"profiles.":[110],"The":[111],"proposed":[112],"model":[113,182],"was":[114,147],"first":[115],"pre-trained":[116],"labels.":[126],"After":[127],"that,":[128],"meth-SemiCancer":[129,167,194,206],"generated":[130],"pseudo-subtypes":[132],"without":[137],"information":[139],"model's":[143],"prediction.":[144],"Finally,":[145],"fine-tuning":[146],"performed":[148],"both":[150],"labeled":[152],"unlabeled":[154,185],"datasets.":[155],"CONCLUSIONS:":[156],"From":[157],"performance":[159],"comparison":[160],"standard":[163],"machine":[164],"learning-based":[165],"classifiers,":[166],"achieved":[168],"highest":[170],"average":[171],"F1-score":[172],"Matthews":[174],"correlation":[175],"coefficient,":[176],"outperforming":[177],"other":[178],"methods.":[179],"Fine-tuning":[180],"patient":[186],"by":[188],"providing":[189],"pseudo-subtypes,":[192],"encouraged":[193],"generalize":[196],"better":[197],"than":[198],"supervised":[200],"neural":[201],"network-based":[202],"method.":[205],"publicly":[208],"available":[209],"at":[210],"https://github.com/cbi-bioinfo/meth-SemiCancer":[211],".":[212]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}