{"id":"https://openalex.org/W4311575796","doi":"https://doi.org/10.1186/s12859-022-05074-2","title":"Automatic identifying and counting blood cells in smear images by using single shot detector and Taguchi method","display_name":"Automatic identifying and counting blood cells in smear images by using single shot detector and Taguchi method","publication_year":2022,"publication_date":"2022-12-08","ids":{"openalex":"https://openalex.org/W4311575796","doi":"https://doi.org/10.1186/s12859-022-05074-2","pmid":"https://pubmed.ncbi.nlm.nih.gov/36482316"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-022-05074-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-05074-2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-05074-2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-05074-2","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030172333","display_name":"Yao\u2010Mei Chen","orcid":"https://orcid.org/0000-0003-1172-7718"},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yao-Mei Chen","raw_affiliation_strings":["School of Nursing, Kaohsiung Medical University, Kaohsiung, 807, Taiwan","Superintendent Office, Kaohsiung Medical University Hospital, Kaohsiung, 807, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Nursing, Kaohsiung Medical University, Kaohsiung, 807, Taiwan","institution_ids":["https://openalex.org/I152743029"]},{"raw_affiliation_string":"Superintendent Office, Kaohsiung Medical University Hospital, Kaohsiung, 807, Taiwan","institution_ids":["https://openalex.org/I152743029"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057953757","display_name":"Jinn\u2010Tsong Tsai","orcid":"https://orcid.org/0000-0002-1531-5027"},"institutions":[{"id":"https://openalex.org/I1309796872","display_name":"National Pingtung University","ror":"https://ror.org/03z698x91","country_code":"TW","type":"education","lineage":["https://openalex.org/I1309796872"]},{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Jinn-Tsong Tsai","raw_affiliation_strings":["Department of Computer Science and Artificial Intelligence, National Pingtung University, Pingtung, 900, Taiwan. jttsai@mail.nptu.edu.tw","Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, 807, Taiwan. jttsai@mail.nptu.edu.tw","Department of Computer Science and Artificial Intelligence, National Pingtung University, Pingtung, 900, Taiwan"],"raw_orcid":"https://orcid.org/0000-0002-1531-5027","affiliations":[{"raw_affiliation_string":"Department of Computer Science and Artificial Intelligence, National Pingtung University, Pingtung, 900, Taiwan. jttsai@mail.nptu.edu.tw","institution_ids":["https://openalex.org/I1309796872"]},{"raw_affiliation_string":"Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, 807, Taiwan. jttsai@mail.nptu.edu.tw","institution_ids":["https://openalex.org/I152743029"]},{"raw_affiliation_string":"Department of Computer Science and Artificial Intelligence, National Pingtung University, Pingtung, 900, Taiwan","institution_ids":["https://openalex.org/I1309796872"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069961953","display_name":"Wen\u2010Hsien Ho","orcid":"https://orcid.org/0000-0001-6194-0563"},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I4210121532","display_name":"Ministry of Health and Welfare","ror":"https://ror.org/024w0ge69","country_code":"TW","type":"government","lineage":["https://openalex.org/I4210121532","https://openalex.org/I4405257903"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Wen-Hsien Ho","raw_affiliation_strings":["Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, 807, Taiwan. whho@kmu.edu.tw","Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, 807, Taiwan. whho@kmu.edu.tw","Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, 807, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, 807, Taiwan. whho@kmu.edu.tw","institution_ids":["https://openalex.org/I152743029"]},{"raw_affiliation_string":"Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, 807, Taiwan. whho@kmu.edu.tw","institution_ids":["https://openalex.org/I152743029"]},{"raw_affiliation_string":"Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, 807, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I4210121532"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5057953757"],"corresponding_institution_ids":["https://openalex.org/I1309796872","https://openalex.org/I152743029"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.4207,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.82985516,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"22","issue":"S5","first_page":"635","last_page":"635"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.984499990940094,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.984499990940094,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperparameter","display_name":"Hyperparameter","score":0.8744107484817505},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6847020983695984},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6157094836235046},{"id":"https://openalex.org/keywords/taguchi-methods","display_name":"Taguchi methods","score":0.5800797939300537},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5242674350738525},{"id":"https://openalex.org/keywords/detector","display_name":"Detector","score":0.47487756609916687},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.34106773138046265},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.2214333713054657}],"concepts":[{"id":"https://openalex.org/C8642999","wikidata":"https://www.wikidata.org/wiki/Q4171168","display_name":"Hyperparameter","level":2,"score":0.8744107484817505},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6847020983695984},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6157094836235046},{"id":"https://openalex.org/C83469408","wikidata":"https://www.wikidata.org/wiki/Q2036525","display_name":"Taguchi methods","level":2,"score":0.5800797939300537},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5242674350738525},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.47487756609916687},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.34106773138046265},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.2214333713054657},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001773","descriptor_name":"Blood Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001773","descriptor_name":"Blood Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001773","descriptor_name":"Blood Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-022-05074-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-05074-2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-05074-2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:36482316","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36482316","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:3c8a6406781a48a59ee3e5230246bf31","is_oa":true,"landing_page_url":"https://doaj.org/article/3c8a6406781a48a59ee3e5230246bf31","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 22, Iss S5, Pp 1-18 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9732976","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9732976","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-022-05074-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-05074-2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-05074-2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2205640134","display_name":null,"funder_award_id":"MOST 109","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"},{"id":"https://openalex.org/G3213060376","display_name":null,"funder_award_id":"MOST 109-2221-E-153-005-MY3","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"},{"id":"https://openalex.org/G3862518167","display_name":null,"funder_award_id":"MOST 109-","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"},{"id":"https://openalex.org/G4407506782","display_name":null,"funder_award_id":"109-2221-E-153-005-MY3","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"},{"id":"https://openalex.org/G5309383408","display_name":null,"funder_award_id":"005-MY3","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"},{"id":"https://openalex.org/G5866620785","display_name":null,"funder_award_id":"MOST 109-2221-E-153-005-MY3","funder_id":"https://openalex.org/F4320309618","funder_display_name":"Ministry of Science and Technology"},{"id":"https://openalex.org/G7239784576","display_name":null,"funder_award_id":"MOST 110-2221-E-037-005","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"},{"id":"https://openalex.org/G7664286870","display_name":null,"funder_award_id":"110-2410-H-037-001","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"},{"id":"https://openalex.org/G8985157498","display_name":null,"funder_award_id":"MOST 109-2221","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"}],"funders":[{"id":"https://openalex.org/F4320309618","display_name":"Ministry of Science and Technology","ror":"https://ror.org/02b207r52"},{"id":"https://openalex.org/F4320322795","display_name":"Ministry of Science and Technology, Taiwan","ror":"https://ror.org/02kv4zf79"},{"id":"https://openalex.org/F4320324663","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49"},{"id":"https://openalex.org/F4320336031","display_name":"Intelligent Manufacturing Research Center","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4311575796.pdf","grobid_xml":"https://content.openalex.org/works/W4311575796.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W13924470","https://openalex.org/W409509505","https://openalex.org/W1993351885","https://openalex.org/W2117539524","https://openalex.org/W2194775991","https://openalex.org/W2224945135","https://openalex.org/W2558245908","https://openalex.org/W2589005338","https://openalex.org/W2787108247","https://openalex.org/W2945576057","https://openalex.org/W2953681063","https://openalex.org/W2968859244","https://openalex.org/W2982084551","https://openalex.org/W3010540599","https://openalex.org/W3016457468","https://openalex.org/W3092605947","https://openalex.org/W3128053574","https://openalex.org/W3159830173","https://openalex.org/W3179072224","https://openalex.org/W3212240274","https://openalex.org/W3214657685","https://openalex.org/W4206349633","https://openalex.org/W4206978330"],"related_works":["https://openalex.org/W2141801573","https://openalex.org/W2140186469","https://openalex.org/W4390421286","https://openalex.org/W4280563792","https://openalex.org/W2042858286","https://openalex.org/W4318719684","https://openalex.org/W4389724018","https://openalex.org/W4318559728","https://openalex.org/W3183136280","https://openalex.org/W2186534316"],"abstract_inverted_index":{"BACKGROUND:":[0],"Researchers":[1],"have":[2],"tried":[3],"to":[4,23,75,116],"identify":[5],"and":[6,41,64,92,124,255,263],"count":[7],"different":[8,66],"blood":[9,34,39,43,67,94,126,195,238,257,261,265],"cells":[10,35,68,196,262],"in":[11,253],"microscopic":[12],"smear":[13],"images":[14,173,189,240],"by":[15,141,213,232],"using":[16,206,225],"deep":[17],"learning":[18],"methods":[19],"of":[20,33,55,80,83,100,132,136,150,162,178,194,202,209,221,228],"artificial":[21],"intelligence":[22],"solve":[24],"the":[25,48,56,84,101,111,118,129,137,142,151,159,163,179,191,199,203,207,214,222,226,233,243,246],"highly":[26],"time-consuming":[27],"problem.":[28],"RESULTS:":[29],"The":[30,96,154],"three":[31],"types":[32],"are":[36],"platelets,":[37],"red":[38,264],"cells,":[40,258],"white":[42,260],"cells.":[44,95,127,266],"This":[45],"study":[46],"used":[47],"Resnet50":[49,85,97,133],"network":[50,54,86,99],"as":[51],"a":[52,72,77],"backbone":[53,98,134],"single":[57],"shot":[58],"detector":[59],"(SSD)":[60],"for":[61,87,90,122,146],"automatically":[62],"identifying":[63,91,123,254],"counting":[65,93,125,256],"and,":[69],"meanwhile,":[70],"proposed":[71,247],"systematic":[73],"method":[74,145,216],"find":[76],"better":[78,175,218],"combination":[79,208,227],"algorithm":[81,106,130,210,229],"hyperparameters":[82,131,211,230],"promoting":[88,147],"accuracy":[89,149,161,201,252],"SSD":[102,138],"with":[103,166,182],"its":[104],"optimized":[105,140],"hyperparameters,":[107],"which":[108],"is":[109],"called":[110],"Resnet50-SSD":[112,152,164,180,204,223,248],"model,":[113],"was":[114,174,217],"developed":[115],"enhance":[117],"feature":[119],"extraction":[120],"ability":[121],"Furthermore,":[128],"networks":[135],"were":[139],"Taguchi":[143,215],"experimental":[144,155],"detection":[148,160,200],"model.":[153],"result":[156],"shows":[157],"that":[158,177,220],"model":[165,181,205,224,249],"512":[167,169],"\u00d7":[168,170,184,186],"3":[171,187],"input":[172,188],"than":[176,219],"300":[183,185],"on":[190],"test":[192],"set":[193],"images.":[197],"Additionally,":[198],"got":[212],"given":[231],"Matlab":[234],"example.":[235],"CONCLUSION:":[236],"In":[237],"cell":[239],"acquired":[241],"from":[242],"BCCD":[244],"dataset,":[245],"had":[250],"higher":[251],"especially":[259]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}