{"id":"https://openalex.org/W4295759232","doi":"https://doi.org/10.1186/s12859-022-04907-4","title":"Pattern matching for high precision detection of LINE-1s in human genomes","display_name":"Pattern matching for high precision detection of LINE-1s in human genomes","publication_year":2022,"publication_date":"2022-09-13","ids":{"openalex":"https://openalex.org/W4295759232","doi":"https://doi.org/10.1186/s12859-022-04907-4","pmid":"https://pubmed.ncbi.nlm.nih.gov/36100885"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-022-04907-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04907-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04907-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04907-4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091547990","display_name":"Juan O. L\u00f3pez","orcid":"https://orcid.org/0000-0003-1113-2511"},"institutions":[{"id":"https://openalex.org/I200399037","display_name":"University of Puerto Rico System","ror":"https://ror.org/02yg0nm07","country_code":"PR","type":"education","lineage":["https://openalex.org/I200399037"]},{"id":"https://openalex.org/I89458556","display_name":"University of Puerto Rico at Arecibo","ror":"https://ror.org/038z2eg27","country_code":"PR","type":"education","lineage":["https://openalex.org/I200399037","https://openalex.org/I89458556"]}],"countries":["PR"],"is_corresponding":true,"raw_author_name":"Juan O. Lopez","raw_affiliation_strings":["Department of Computer Science, University of Puerto Rico, Arecibo, Puerto Rico. juano.lopez@upr.edu","Department of Computer Science, University of Puerto Rico, Arecibo, Puerto Rico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Puerto Rico, Arecibo, Puerto Rico. juano.lopez@upr.edu","institution_ids":["https://openalex.org/I200399037","https://openalex.org/I89458556"]},{"raw_affiliation_string":"Department of Computer Science, University of Puerto Rico, Arecibo, Puerto Rico","institution_ids":["https://openalex.org/I89458556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082469529","display_name":"Jaime Seguel","orcid":null},"institutions":[{"id":"https://openalex.org/I60388903","display_name":"University of Puerto Rico-Mayaguez","ror":"https://ror.org/00wek6x04","country_code":"PR","type":"education","lineage":["https://openalex.org/I200399037","https://openalex.org/I60388903"]}],"countries":["PR"],"is_corresponding":false,"raw_author_name":"Jaime Seguel","raw_affiliation_strings":["Department of Computer Science and Engineering, University of Puerto Rico, Mayag\u00fcez, Puerto Rico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, University of Puerto Rico, Mayag\u00fcez, Puerto Rico","institution_ids":["https://openalex.org/I60388903"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091219949","display_name":"Andres Chamorro","orcid":null},"institutions":[{"id":"https://openalex.org/I60388903","display_name":"University of Puerto Rico-Mayaguez","ror":"https://ror.org/00wek6x04","country_code":"PR","type":"education","lineage":["https://openalex.org/I200399037","https://openalex.org/I60388903"]}],"countries":["PR"],"is_corresponding":false,"raw_author_name":"Andres Chamorro","raw_affiliation_strings":["Department of Computer Science and Engineering, University of Puerto Rico, Mayag\u00fcez, Puerto Rico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, University of Puerto Rico, Mayag\u00fcez, Puerto Rico","institution_ids":["https://openalex.org/I60388903"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101757397","display_name":"Kenneth S. Ramos","orcid":null},"institutions":[{"id":"https://openalex.org/I125029298","display_name":"Texas A&M Health Science Center","ror":"https://ror.org/01tx6pn92","country_code":"US","type":"education","lineage":["https://openalex.org/I125029298","https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth S. Ramos","raw_affiliation_strings":["Institute of Biosciences and Technology, Texas A&M Health, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biosciences and Technology, Texas A&M Health, Houston, TX, USA","institution_ids":["https://openalex.org/I125029298"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5091547990"],"corresponding_institution_ids":["https://openalex.org/I200399037","https://openalex.org/I89458556"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":0.3886,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.70993409,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"23","issue":"1","first_page":"375","last_page":"375"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13664","display_name":"Genome Rearrangement Algorithms","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.728060245513916},{"id":"https://openalex.org/keywords/human-genome","display_name":"Human genome","score":0.6804853677749634},{"id":"https://openalex.org/keywords/retrotransposon","display_name":"Retrotransposon","score":0.6199511289596558},{"id":"https://openalex.org/keywords/matching","display_name":"Matching (statistics)","score":0.6131962537765503},{"id":"https://openalex.org/keywords/heuristic","display_name":"Heuristic","score":0.5814558267593384},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.5603846907615662},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5155520439147949},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5024046897888184},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.47288957238197327},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.46169838309288025},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.4553038477897644},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.43272367119789124},{"id":"https://openalex.org/keywords/reference-genome","display_name":"Reference genome","score":0.42415037751197815},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.40023279190063477},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.37994956970214844},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.35833266377449036},{"id":"https://openalex.org/keywords/transposable-element","display_name":"Transposable element","score":0.25067052245140076},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.22012430429458618},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2188173532485962},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.11296743154525757},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.09406933188438416}],"concepts":[{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.728060245513916},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.6804853677749634},{"id":"https://openalex.org/C7029365","wikidata":"https://www.wikidata.org/wiki/Q413988","display_name":"Retrotransposon","level":5,"score":0.6199511289596558},{"id":"https://openalex.org/C165064840","wikidata":"https://www.wikidata.org/wiki/Q1321061","display_name":"Matching (statistics)","level":2,"score":0.6131962537765503},{"id":"https://openalex.org/C173801870","wikidata":"https://www.wikidata.org/wiki/Q201413","display_name":"Heuristic","level":2,"score":0.5814558267593384},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.5603846907615662},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5155520439147949},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5024046897888184},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.47288957238197327},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46169838309288025},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.4553038477897644},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.43272367119789124},{"id":"https://openalex.org/C192953774","wikidata":"https://www.wikidata.org/wiki/Q7307127","display_name":"Reference genome","level":4,"score":0.42415037751197815},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.40023279190063477},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.37994956970214844},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.35833266377449036},{"id":"https://openalex.org/C4918238","wikidata":"https://www.wikidata.org/wiki/Q121438","display_name":"Transposable element","level":4,"score":0.25067052245140076},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.22012430429458618},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2188173532485962},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11296743154525757},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.09406933188438416},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018626","descriptor_name":"Retroelements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018626","descriptor_name":"Retroelements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018626","descriptor_name":"Retroelements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020084","descriptor_name":"Long Interspersed Nucleotide Elements","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020084","descriptor_name":"Long Interspersed Nucleotide Elements","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020084","descriptor_name":"Long Interspersed Nucleotide Elements","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D056915","descriptor_name":"DNA Copy Number Variations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056915","descriptor_name":"DNA Copy Number Variations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056915","descriptor_name":"DNA Copy Number Variations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-022-04907-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04907-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04907-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:36100885","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36100885","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:ecde935e07404c089cde8a87e026fd0e","is_oa":true,"landing_page_url":"https://doaj.org/article/ecde935e07404c089cde8a87e026fd0e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 23, Iss 1, Pp 1-17 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9472350","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9472350","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-022-04907-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04907-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04907-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4295759232.pdf","grobid_xml":"https://content.openalex.org/works/W4295759232.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1828154403","https://openalex.org/W2023132255","https://openalex.org/W2045807857","https://openalex.org/W2051274365","https://openalex.org/W2055043387","https://openalex.org/W2091479795","https://openalex.org/W2103441770","https://openalex.org/W2108234281","https://openalex.org/W2114850508","https://openalex.org/W2137759177","https://openalex.org/W2139747296","https://openalex.org/W2146821392","https://openalex.org/W2159640103","https://openalex.org/W2171976338","https://openalex.org/W2296336302","https://openalex.org/W2347011735","https://openalex.org/W2519989212","https://openalex.org/W2533759132","https://openalex.org/W2784788330","https://openalex.org/W2785096815","https://openalex.org/W3168724350"],"related_works":["https://openalex.org/W2281520406","https://openalex.org/W111131418","https://openalex.org/W2091479795","https://openalex.org/W2051541780","https://openalex.org/W2114924552","https://openalex.org/W2412943124","https://openalex.org/W2146892790","https://openalex.org/W1987119677","https://openalex.org/W2000974906","https://openalex.org/W2133994800"],"abstract_inverted_index":{"BACKGROUND:":[0],"Long":[1],"interspersed":[2],"element":[3],"1":[4],"(LINE-1":[5],"or":[6,71],"L1)":[7],"retrotransposons":[8],"are":[9,61,97],"mobile":[10],"elements":[11],"that":[12,59,96,299],"constitute":[13],"17-20%":[14],"of":[15,40,43,68,94,114,121,133,163,197,202,206,212,218,237,257,265,279,289,294],"the":[16,41,75,92,106,119,195,200,221,227,242,244,252,277],"human":[17,27,76],"genome.":[18,192,222,253],"Strong":[19],"correlations":[20,305],"between":[21,306],"abnormal":[22],"L1":[23,44,125,142,164,280,307,315],"expression":[24],"and":[25,130,150,159,181,310,317],"several":[26],"diseases":[28],"have":[29],"been":[30],"reported.":[31],"This":[32,103],"has":[33],"motivated":[34],"increasing":[35],"interest":[36],"in":[37,47,74,177,220,224],"accurate":[38,112],"quantification":[39],"number":[42,93,185,309],"copies":[45,143,162],"present":[46,73],"any":[48],"given":[49],"biologic":[50],"specimen.":[51],"A":[52],"main":[53],"obstacle":[54],"toward":[55],"this":[56],"aim":[57],"is":[58,270],"L1s":[60,100,176],"relatively":[62,166],"long":[63],"DNA":[64],"segments":[65,95,281],"with":[66,144,165,187,262,291,314],"regions":[67],"high":[69,145,167],"variability,":[70],"largely":[72],"genome":[77,180],"as":[78,88,91],"truncated":[79,158],"fragments.":[80],"These":[81],"particularities":[82],"render":[83],"traditional":[84],"alignment":[85],"strategies,":[86],"such":[87],"seed-and-extend":[89,225,274],"inefficient,":[90],"similar":[98],"to":[99,174,182,189,194],"explodes":[101],"exponentially.":[102],"study":[104],"uses":[105],"pattern":[107,122,217,228,300],"matching":[108,123,139,229,269,301],"methodology":[109],"for":[110,124,276],"more":[111,271],"identification":[113],"L1s.":[115],"We":[116,297],"validate":[117],"experimentally":[118],"superiority":[120],"detection":[126,278],"over":[127],"alternative":[128],"methods":[129,275],"discuss":[131],"some":[132,263],"its":[134],"potential":[135],"applications.":[136],"RESULTS:":[137],"Pattern":[138,268],"detected":[140,157],"full-length":[141],"precision,":[146],"reasonable":[147],"computational":[148],"time,":[149],"no":[151],"prior":[152],"input":[153],"information.":[154],"It":[155],"also":[156],"significantly":[160],"altered":[161],"precision.":[168],"The":[169,254],"method":[170],"was":[171,199,246],"effectively":[172],"used":[173],"annotate":[175],"a":[178,190,203,210,215,286],"target":[179],"calculate":[183],"copy":[184,308],"variation":[186],"respect":[188],"reference":[191],"Crucial":[193],"success":[196],"implementation":[198],"selection":[201],"small":[204],"set":[205,211,288],"k-mer":[207,233],"probes":[208],"from":[209],"sequences":[213,290],"presenting":[214],"stable":[216],"distribution":[219,249],"As":[223],"methods,":[226],"algorithm":[230],"sowed":[231],"these":[232],"probes,":[234],"but":[235],"instead":[236],"using":[238],"heuristic":[239],"extensions":[240],"around":[241],"seeds,":[243],"analysis":[245],"based":[247],"on":[248,285],"patterns":[250],"within":[251],"desired":[255],"level":[256],"precision":[258],"could":[259],"be":[260],"adjusted,":[261],"loss":[264],"recall.":[266],"CONCLUSION:":[267],"efficient":[272],"than":[273],"whose":[282],"characterization":[283],"depends":[284],"finite":[287],"common":[292],"areas":[293],"low":[295],"variability.":[296],"propose":[298],"may":[302],"help":[303],"establish":[304],"disease":[311],"states":[312],"associated":[313],"mobilization":[316],"evolution.":[318]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}