{"id":"https://openalex.org/W4294308052","doi":"https://doi.org/10.1186/s12859-022-04900-x","title":"Learning a confidence score and the latent space of a new supervised autoencoder for diagnosis and prognosis in clinical metabolomic studies","display_name":"Learning a confidence score and the latent space of a new supervised autoencoder for diagnosis and prognosis in clinical metabolomic studies","publication_year":2022,"publication_date":"2022-09-01","ids":{"openalex":"https://openalex.org/W4294308052","doi":"https://doi.org/10.1186/s12859-022-04900-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/36050631"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-022-04900-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04900-x","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12859-022-04900-x.pdf","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s12859-022-04900-x.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045198485","display_name":"David Chardin","orcid":"https://orcid.org/0000-0003-1497-1521"},"institutions":[{"id":"https://openalex.org/I201841394","display_name":"Universit\u00e9 C\u00f4te d'Azur","ror":"https://ror.org/019tgvf94","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I4210113668","display_name":"Direction de la Recherche Fondamentale","ror":"https://ror.org/01yvj5k91","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I4210113668"]},{"id":"https://openalex.org/I4210151846","display_name":"Centre Antoine Lacassagne","ror":"https://ror.org/05hmfw828","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210151846"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"David Chardin","raw_affiliation_strings":["Centre Antoine Lacassagne, Universit\u00e9 C\u00f4te d'Azur (UCA), Nice, France","Transporters in Imaging and Radiotherapy in Oncology (TIRO), Direction de la Recherche Fondamentale (DRF), Institut des sciences du vivant Fr\u00e9deric Joliot, Commissariat \u00e0 l'Energie Atomique et aux \u00e9nergies alternatives (CEA), Universit\u00e9 C\u00f4te d'Azur (UCA), Nice, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre Antoine Lacassagne, Universit\u00e9 C\u00f4te d'Azur (UCA), Nice, France","institution_ids":["https://openalex.org/I4210151846"]},{"raw_affiliation_string":"Transporters in Imaging and Radiotherapy in Oncology (TIRO), Direction de la Recherche Fondamentale (DRF), Institut des sciences du vivant Fr\u00e9deric Joliot, Commissariat \u00e0 l'Energie Atomique et aux \u00e9nergies alternatives (CEA), Universit\u00e9 C\u00f4te d'Azur (UCA), Nice, France","institution_ids":["https://openalex.org/I201841394","https://openalex.org/I2738703131","https://openalex.org/I4210113668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032377647","display_name":"Cyprien Gille","orcid":"https://orcid.org/0000-0003-1974-1039"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I201841394","display_name":"Universit\u00e9 C\u00f4te d'Azur","ror":"https://ror.org/019tgvf94","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394"]},{"id":"https://openalex.org/I4210106479","display_name":"Laboratoire d'Informatique, Signaux et Syst\u00e8mes de Sophia Antipolis","ror":"https://ror.org/01215r597","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I201841394","https://openalex.org/I4210106479","https://openalex.org/I4210159245"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Cyprien Gille","raw_affiliation_strings":["Laboratoire d'Informatique, Signaux et Syst\u00e8mes de Sophia Antipolis (I3S), Centre de Recherche Scientifique (CNRS), Universit\u00e9 C\u00f4te d'Azur (UCA), Sophia Antipolis, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Informatique, Signaux et Syst\u00e8mes de Sophia Antipolis (I3S), Centre de Recherche Scientifique (CNRS), Universit\u00e9 C\u00f4te d'Azur (UCA), Sophia Antipolis, France","institution_ids":["https://openalex.org/I201841394","https://openalex.org/I1294671590","https://openalex.org/I4210106479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044172508","display_name":"Thierry Pourcher","orcid":"https://orcid.org/0000-0003-2839-4622"},"institutions":[{"id":"https://openalex.org/I201841394","display_name":"Universit\u00e9 C\u00f4te d'Azur","ror":"https://ror.org/019tgvf94","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I4210113668","display_name":"Direction de la Recherche Fondamentale","ror":"https://ror.org/01yvj5k91","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I4210113668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Thierry Pourcher","raw_affiliation_strings":["Transporters in Imaging and Radiotherapy in Oncology (TIRO), Direction de la Recherche Fondamentale (DRF), Institut des sciences du vivant Fr\u00e9deric Joliot, Commissariat \u00e0 l'Energie Atomique et aux \u00e9nergies alternatives (CEA), Universit\u00e9 C\u00f4te d'Azur (UCA), Nice, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Transporters in Imaging and Radiotherapy in Oncology (TIRO), Direction de la Recherche Fondamentale (DRF), Institut des sciences du vivant Fr\u00e9deric Joliot, Commissariat \u00e0 l'Energie Atomique et aux \u00e9nergies alternatives (CEA), Universit\u00e9 C\u00f4te d'Azur (UCA), Nice, France","institution_ids":["https://openalex.org/I201841394","https://openalex.org/I2738703131","https://openalex.org/I4210113668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053536156","display_name":"Olivier Humbert","orcid":"https://orcid.org/0000-0003-4440-5416"},"institutions":[{"id":"https://openalex.org/I201841394","display_name":"Universit\u00e9 C\u00f4te d'Azur","ror":"https://ror.org/019tgvf94","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I4210113668","display_name":"Direction de la Recherche Fondamentale","ror":"https://ror.org/01yvj5k91","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I4210113668"]},{"id":"https://openalex.org/I4210151846","display_name":"Centre Antoine Lacassagne","ror":"https://ror.org/05hmfw828","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210151846"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Olivier Humbert","raw_affiliation_strings":["Centre Antoine Lacassagne, Universit\u00e9 C\u00f4te d'Azur (UCA), Nice, France","Transporters in Imaging and Radiotherapy in Oncology (TIRO), Direction de la Recherche Fondamentale (DRF), Institut des sciences du vivant Fr\u00e9deric Joliot, Commissariat \u00e0 l'Energie Atomique et aux \u00e9nergies alternatives (CEA), Universit\u00e9 C\u00f4te d'Azur (UCA), Nice, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre Antoine Lacassagne, Universit\u00e9 C\u00f4te d'Azur (UCA), Nice, France","institution_ids":["https://openalex.org/I4210151846"]},{"raw_affiliation_string":"Transporters in Imaging and Radiotherapy in Oncology (TIRO), Direction de la Recherche Fondamentale (DRF), Institut des sciences du vivant Fr\u00e9deric Joliot, Commissariat \u00e0 l'Energie Atomique et aux \u00e9nergies alternatives (CEA), Universit\u00e9 C\u00f4te d'Azur (UCA), Nice, France","institution_ids":["https://openalex.org/I201841394","https://openalex.org/I2738703131","https://openalex.org/I4210113668"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108556119","display_name":"Michel Barlaud","orcid":null},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I201841394","display_name":"Universit\u00e9 C\u00f4te d'Azur","ror":"https://ror.org/019tgvf94","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394"]},{"id":"https://openalex.org/I4210106479","display_name":"Laboratoire d'Informatique, Signaux et Syst\u00e8mes de Sophia Antipolis","ror":"https://ror.org/01215r597","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I201841394","https://openalex.org/I4210106479","https://openalex.org/I4210159245"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Michel Barlaud","raw_affiliation_strings":["Laboratoire d'Informatique, Signaux et Syst\u00e8mes de Sophia Antipolis (I3S), Centre de Recherche Scientifique (CNRS), Universit\u00e9 C\u00f4te d'Azur (UCA), Sophia Antipolis, France. barlaud@i3s.unice.fr","Laboratoire d'Informatique, Signaux et Syst\u00e8mes de Sophia Antipolis (I3S), Centre de Recherche Scientifique (CNRS), Universit\u00e9 C\u00f4te d'Azur (UCA), Sophia Antipolis, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Informatique, Signaux et Syst\u00e8mes de Sophia Antipolis (I3S), Centre de Recherche Scientifique (CNRS), Universit\u00e9 C\u00f4te d'Azur (UCA), Sophia Antipolis, France. barlaud@i3s.unice.fr","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210106479"]},{"raw_affiliation_string":"Laboratoire d'Informatique, Signaux et Syst\u00e8mes de Sophia Antipolis (I3S), Centre de Recherche Scientifique (CNRS), Universit\u00e9 C\u00f4te d'Azur (UCA), Sophia Antipolis, France","institution_ids":["https://openalex.org/I201841394","https://openalex.org/I1294671590","https://openalex.org/I4210106479"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5108556119"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I201841394","https://openalex.org/I4210106479"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.0891,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.75881279,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":98},"biblio":{"volume":"23","issue":"1","first_page":"361","last_page":"361"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9314000010490417,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9314000010490417,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.008999999612569809,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/softmax-function","display_name":"Softmax function","score":0.8408194780349731},{"id":"https://openalex.org/keywords/interpretability","display_name":"Interpretability","score":0.7638323307037354},{"id":"https://openalex.org/keywords/autoencoder","display_name":"Autoencoder","score":0.7499804496765137},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7420265078544617},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.6672109961509705},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.624405562877655},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.5427020788192749},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.5167521834373474},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.5037807822227478},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.4883396327495575},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.4619043469429016},{"id":"https://openalex.org/keywords/confidence-interval","display_name":"Confidence interval","score":0.4502633213996887},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3878211975097656},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.35993894934654236},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.12045910954475403},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.1029958426952362}],"concepts":[{"id":"https://openalex.org/C188441871","wikidata":"https://www.wikidata.org/wiki/Q7554146","display_name":"Softmax function","level":3,"score":0.8408194780349731},{"id":"https://openalex.org/C2781067378","wikidata":"https://www.wikidata.org/wiki/Q17027399","display_name":"Interpretability","level":2,"score":0.7638323307037354},{"id":"https://openalex.org/C101738243","wikidata":"https://www.wikidata.org/wiki/Q786435","display_name":"Autoencoder","level":3,"score":0.7499804496765137},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7420265078544617},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.6672109961509705},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.624405562877655},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.5427020788192749},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.5167521834373474},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.5037807822227478},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.4883396327495575},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.4619043469429016},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.4502633213996887},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3878211975097656},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.35993894934654236},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.12045910954475403},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.1029958426952362}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1186/s12859-022-04900-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04900-x","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12859-022-04900-x.pdf","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:36050631","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36050631","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:orbi.umons.ac.be:20.500.12907/53767","is_oa":true,"landing_page_url":"https://orbi.umons.ac.be/handle/20.500.12907/53767","pdf_url":"https://orbi.umons.ac.be/bitstream/20.500.12907/53767/1/Chardin%20et%20al.%20-%202022%20-%20Learning%20a%20confidence%20score%20and%20the%20latent%20space%20o.pdf","source":{"id":"https://openalex.org/S7407055454","display_name":"ORBi UMONS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, 23 (1), 361 (2022-09-01)","raw_type":"http://purl.org/coar/resource_type/c_6501"},{"id":"pmh:oai:HAL:hal-03839284v1","is_oa":false,"landing_page_url":"https://hal.science/hal-03839284","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, 2022, 23 (1), pp.361. ⟨10.1186/s12859-022-04900-x⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:hal-04235799v1","is_oa":false,"landing_page_url":"https://hal.science/hal-04235799","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, 2022, 23 (1), pp.361. ⟨10.1186/s12859-022-04900-x⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:b2552e944bb34afd825c5b0168997141","is_oa":true,"landing_page_url":"https://doaj.org/article/b2552e944bb34afd825c5b0168997141","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 23, Iss 1, Pp 1-16 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9434875","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9434875","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-022-04900-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04900-x","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12859-022-04900-x.pdf","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions","score":0.49000000953674316}],"awards":[{"id":"https://openalex.org/G2113015678","display_name":"3IA C\u00f4te d'Azur","funder_award_id":"ANR-19-P3IA-0002","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G5348977864","display_name":null,"funder_award_id":"ANR-15-IDEX-01","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G8800819381","display_name":null,"funder_award_id":"-15-IDEX-01","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4294308052.pdf","grobid_xml":"https://content.openalex.org/works/W4294308052.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W1523985187","https://openalex.org/W2034712902","https://openalex.org/W2072816950","https://openalex.org/W2094254128","https://openalex.org/W2097360283","https://openalex.org/W2101239722","https://openalex.org/W2102636708","https://openalex.org/W2113315423","https://openalex.org/W2132066552","https://openalex.org/W2135046866","https://openalex.org/W2180180824","https://openalex.org/W2311607323","https://openalex.org/W2474484769","https://openalex.org/W2489822048","https://openalex.org/W2561981131","https://openalex.org/W2735421790","https://openalex.org/W2767582147","https://openalex.org/W2792165586","https://openalex.org/W2891248079","https://openalex.org/W2892587974","https://openalex.org/W2904131971","https://openalex.org/W2962963232","https://openalex.org/W2980773467","https://openalex.org/W2990138404","https://openalex.org/W3003671594","https://openalex.org/W3033134069","https://openalex.org/W3041823559","https://openalex.org/W3087245954","https://openalex.org/W3106271252","https://openalex.org/W3123360092","https://openalex.org/W3135243128","https://openalex.org/W3158143432","https://openalex.org/W3161942977","https://openalex.org/W3193938195","https://openalex.org/W4206552487","https://openalex.org/W4210311545","https://openalex.org/W4289236186","https://openalex.org/W4294541781"],"related_works":["https://openalex.org/W2769441402","https://openalex.org/W2594436708","https://openalex.org/W4361806667","https://openalex.org/W4360994128","https://openalex.org/W3086240734","https://openalex.org/W2951850672","https://openalex.org/W2789476480","https://openalex.org/W4388745254","https://openalex.org/W2980082554","https://openalex.org/W1517228774"],"abstract_inverted_index":{"BACKGROUND:":[0],"Presently,":[1],"there":[2],"is":[3],"a":[4,36,85,95,115,123,127,135,142,225],"wide":[5],"variety":[6],"of":[7,38,72,103,113,158,164,178],"classification":[8,25,102],"methods":[9,43,197],"and":[10,27,60,126,132,167,185,202],"deep":[11],"neural":[12,18,203],"network":[13],"approaches":[14],"in":[15,51,181],"bioinformatics.":[16],"Deep":[17],"networks":[19,204],"have":[20,28],"proven":[21],"their":[22],"effectiveness":[23,163],"for":[24,47,88,101,118,147],"tasks,":[26],"outperformed":[29],"classical":[30,196],"methods,":[31],"but":[32],"they":[33],"suffer":[34],"from":[35],"lack":[37],"interpretability.":[39],"Therefore,":[40],"these":[41],"innovative":[42],"are":[44],"not":[45],"appropriate":[46],"decision":[48],"support":[49,231],"systems":[50],"healthcare.":[52],"Indeed,":[53],"to":[54,57,75,122,133,215,230],"allow":[55],"clinicians":[56],"make":[58],"informed":[59],"well":[61,83],"thought":[62],"out":[63],"decisions,":[64],"the":[65,69,77,111,162,179,182,193,207,211],"algorithm":[66],"should":[67],"provide":[68],"main":[70],"pieces":[71],"information":[73],"used":[74,94],"compute":[76],"predicted":[78],"diagnosis":[79],"and/or":[80],"prognosis,":[81],"as":[82,84],"confidence":[86,116,169,188],"score":[87,117],"this":[89,221],"prediction.":[90],"METHODS:":[91],"Herein,":[92],"we":[93,223],"new":[96,108,136,226],"supervised":[97,172],"autoencoder":[98,173],"(SAE)":[99],"approach":[100],"clinical":[104,159],"metabolomic":[105],"data.":[106],"This":[107],"method":[109,229],"has":[110],"advantage":[112],"providing":[114],"each":[119],"prediction":[120],"thanks":[121],"softmax":[124],"classifier":[125],"meaningful":[128],"latent":[129,183],"space":[130],"visualization":[131],"include":[134],"efficient":[137,187,227],"feature":[138],"selection":[139],"method,":[140],"with":[141],"structured":[143],"constraint,":[144],"which":[145],"allows":[146],"biologically":[148,217],"interpretable":[149],"results.":[150],"RESULTS:":[151],"Experimental":[152],"results":[153],"on":[154,237],"three":[155],"metabolomics":[156,238],"datasets":[157],"samples":[160],"illustrate":[161],"our":[165],"SAE":[166,194,212,228],"its":[168],"score.":[170,189],"The":[171],"provides":[174],"an":[175,186],"accurate":[176],"localization":[177],"patients":[180],"space,":[184],"Experiments":[190],"show":[191],"that":[192],"outperforms":[195],"(PLS-DA,":[198],"Random":[199],"Forests,":[200],"SVM,":[201],"(NN)).":[205],"Furthermore,":[206],"metabolites":[208],"selected":[209],"by":[210],"were":[213],"found":[214],"be":[216],"relevant.":[218],"CONCLUSION:":[219],"In":[220],"paper,":[222],"describe":[224],"diagnostic":[232],"or":[233],"prognostic":[234],"evaluation":[235],"based":[236],"analyses.":[239]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":6}],"updated_date":"2026-07-04T07:58:01.006859","created_date":"2025-10-10T00:00:00"}