{"id":"https://openalex.org/W4290996816","doi":"https://doi.org/10.1186/s12859-022-04883-9","title":"CircWalk: a novel approach to predict CircRNA-disease association based on heterogeneous network representation learning","display_name":"CircWalk: a novel approach to predict CircRNA-disease association based on heterogeneous network representation learning","publication_year":2022,"publication_date":"2022-08-11","ids":{"openalex":"https://openalex.org/W4290996816","doi":"https://doi.org/10.1186/s12859-022-04883-9","pmid":"https://pubmed.ncbi.nlm.nih.gov/35953785"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-022-04883-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04883-9","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04883-9","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04883-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049372676","display_name":"Morteza Kouhsar","orcid":"https://orcid.org/0000-0001-6092-3016"},"institutions":[{"id":"https://openalex.org/I133529467","display_name":"Sharif University of Technology","ror":"https://ror.org/024c2fq17","country_code":"IR","type":"education","lineage":["https://openalex.org/I133529467"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Morteza Kouhsar","raw_affiliation_strings":["BCB Lab, Department of Computer Engineering, Sharif University of Technology, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BCB Lab, Department of Computer Engineering, Sharif University of Technology, Tehran, Iran","institution_ids":["https://openalex.org/I133529467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007661886","display_name":"Esra Kashaninia","orcid":null},"institutions":[{"id":"https://openalex.org/I133529467","display_name":"Sharif University of Technology","ror":"https://ror.org/024c2fq17","country_code":"IR","type":"education","lineage":["https://openalex.org/I133529467"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Esra Kashaninia","raw_affiliation_strings":["BCB Lab, Department of Computer Engineering, Sharif University of Technology, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BCB Lab, Department of Computer Engineering, Sharif University of Technology, Tehran, Iran","institution_ids":["https://openalex.org/I133529467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038200411","display_name":"Behnam Mardani","orcid":null},"institutions":[{"id":"https://openalex.org/I161028277","display_name":"Institute for Advanced Studies in Basic Sciences","ror":"https://ror.org/00bzsst90","country_code":"IR","type":"education","lineage":["https://openalex.org/I161028277"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Behnam Mardani","raw_affiliation_strings":["Department of Computer Science and Information Technology, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Information Technology, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan, Iran","institution_ids":["https://openalex.org/I161028277"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063512925","display_name":"Hamid R. Rabiee","orcid":"https://orcid.org/0000-0002-9835-4493"},"institutions":[{"id":"https://openalex.org/I133529467","display_name":"Sharif University of Technology","ror":"https://ror.org/024c2fq17","country_code":"IR","type":"education","lineage":["https://openalex.org/I133529467"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Hamid R. Rabiee","raw_affiliation_strings":["BCB Lab, Department of Computer Engineering, Sharif University of Technology, Tehran, Iran. rabiee@sharif.edu","BCB Lab, Department of Computer Engineering, Sharif University of Technology, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BCB Lab, Department of Computer Engineering, Sharif University of Technology, Tehran, Iran. rabiee@sharif.edu","institution_ids":["https://openalex.org/I133529467"]},{"raw_affiliation_string":"BCB Lab, Department of Computer Engineering, Sharif University of Technology, Tehran, Iran","institution_ids":["https://openalex.org/I133529467"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5049372676"],"corresponding_institution_ids":["https://openalex.org/I133529467"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.6064,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.64309056,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"23","issue":"1","first_page":"331","last_page":"331"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":0.9510999917984009,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":0.9510999917984009,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.026100000366568565,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/competing-endogenous-rna","display_name":"Competing endogenous RNA","score":0.835947573184967},{"id":"https://openalex.org/keywords/circular-rna","display_name":"Circular RNA","score":0.6754360198974609},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6398241519927979},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.5467929840087891},{"id":"https://openalex.org/keywords/rna-splicing","display_name":"RNA splicing","score":0.4948357939720154},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.45491835474967957},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4527873396873474},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.44346296787261963},{"id":"https://openalex.org/keywords/non-coding-rna","display_name":"Non-coding RNA","score":0.42609116435050964},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.3941114544868469},{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"Long non-coding RNA","score":0.3754284679889679},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3219642639160156},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.2500086724758148},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.17300966382026672}],"concepts":[{"id":"https://openalex.org/C60365752","wikidata":"https://www.wikidata.org/wiki/Q5156306","display_name":"Competing endogenous RNA","level":5,"score":0.835947573184967},{"id":"https://openalex.org/C2775893923","wikidata":"https://www.wikidata.org/wiki/Q17113455","display_name":"Circular RNA","level":4,"score":0.6754360198974609},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6398241519927979},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.5467929840087891},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.4948357939720154},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.45491835474967957},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4527873396873474},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.44346296787261963},{"id":"https://openalex.org/C194993378","wikidata":"https://www.wikidata.org/wiki/Q427087","display_name":"Non-coding RNA","level":4,"score":0.42609116435050964},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.3941114544868469},{"id":"https://openalex.org/C62203573","wikidata":"https://www.wikidata.org/wiki/Q15087973","display_name":"Long non-coding RNA","level":4,"score":0.3754284679889679},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3219642639160156},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2500086724758148},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17300966382026672}],"mesh":[{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-022-04883-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04883-9","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04883-9","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:35953785","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35953785","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:94f8a7bd2fc24b56be63214cf5259b00","is_oa":true,"landing_page_url":"https://doaj.org/article/94f8a7bd2fc24b56be63214cf5259b00","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 23, Iss 1, Pp 1-15 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9367077","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9367077","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-022-04883-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04883-9","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04883-9","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6499999761581421}],"awards":[{"id":"https://openalex.org/G3423493746","display_name":null,"funder_award_id":"96006077","funder_id":"https://openalex.org/F4320322243","funder_display_name":"Iran National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320322243","display_name":"Iran National Science Foundation","ror":"https://ror.org/03sr1ma14"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4290996816.pdf","grobid_xml":"https://content.openalex.org/works/W4290996816.grobid-xml"},"referenced_works_count":67,"referenced_works":["https://openalex.org/W90362830","https://openalex.org/W1032731786","https://openalex.org/W2008056655","https://openalex.org/W2046387002","https://openalex.org/W2058835062","https://openalex.org/W2076491552","https://openalex.org/W2114850508","https://openalex.org/W2115662330","https://openalex.org/W2128049108","https://openalex.org/W2128768066","https://openalex.org/W2147806662","https://openalex.org/W2153234291","https://openalex.org/W2154851992","https://openalex.org/W2158135353","https://openalex.org/W2174734928","https://openalex.org/W2295598076","https://openalex.org/W2346480860","https://openalex.org/W2471934747","https://openalex.org/W2537679995","https://openalex.org/W2557283063","https://openalex.org/W2567465856","https://openalex.org/W2764294957","https://openalex.org/W2765950793","https://openalex.org/W2795917193","https://openalex.org/W2805285958","https://openalex.org/W2807602500","https://openalex.org/W2828141792","https://openalex.org/W2884943532","https://openalex.org/W2885229294","https://openalex.org/W2897721185","https://openalex.org/W2903950532","https://openalex.org/W2909184366","https://openalex.org/W2951739649","https://openalex.org/W2953577247","https://openalex.org/W2966844369","https://openalex.org/W2967043226","https://openalex.org/W2974612830","https://openalex.org/W2993326585","https://openalex.org/W3014630136","https://openalex.org/W3014858999","https://openalex.org/W3020614442","https://openalex.org/W3026308742","https://openalex.org/W3034046925","https://openalex.org/W3036529033","https://openalex.org/W3082893695","https://openalex.org/W3087380499","https://openalex.org/W3093194543","https://openalex.org/W3103443653","https://openalex.org/W3104097132","https://openalex.org/W3117084002","https://openalex.org/W3131511718","https://openalex.org/W3135290444","https://openalex.org/W3135605501","https://openalex.org/W3154103441","https://openalex.org/W3154681489","https://openalex.org/W3156228806","https://openalex.org/W3156522003","https://openalex.org/W3157592001","https://openalex.org/W3162005642","https://openalex.org/W3162189954","https://openalex.org/W3163247020","https://openalex.org/W3163767727","https://openalex.org/W4200110750","https://openalex.org/W4244895750","https://openalex.org/W4246271082","https://openalex.org/W4255156463","https://openalex.org/W6675354045"],"related_works":["https://openalex.org/W3024154810","https://openalex.org/W4303021547","https://openalex.org/W2890741937","https://openalex.org/W4392472091","https://openalex.org/W4205791926","https://openalex.org/W4296598438","https://openalex.org/W2782607110","https://openalex.org/W2400832891","https://openalex.org/W4210559024","https://openalex.org/W2954767213"],"abstract_inverted_index":{"BACKGROUND:":[0],"Several":[1],"types":[2],"of":[3,66,70,77,271,280],"RNA":[4,49,94],"in":[5,11,58,85,148],"the":[6,37,54,59,67,75,91,125,129,134,144,213,232,238,269,272,276],"cell":[7,60],"are":[8,52,251],"usually":[9],"involved":[10],"biological":[12,102],"processes":[13],"with":[14,173,186,286],"multiple":[15,63,121,218],"functions.":[16],"Coding":[17],"RNAs":[18,24,30,57,83],"code":[19],"for":[20,244],"proteins":[21],"while":[22],"non-coding":[23,56],"regulate":[25,74],"gene":[26],"expression.":[27],"Some":[28],"single-strand":[29],"can":[31,104,202],"create":[32],"a":[33,44,153,193,222,255,259],"circular":[34,48],"shape":[35],"via":[36],"back":[38],"splicing":[39],"process":[40],"and":[41,97,116,132,170,189,229,246,257,275],"convert":[42],"into":[43],"new":[45],"type":[46],"called":[47,156],"(circRNA).":[50],"circRNAs":[51,71,184,206,245,281],"among":[53],"essential":[55],"that":[61,165,199,291],"involve":[62],"disorders.":[64],"One":[65],"critical":[68],"functions":[69],"is":[72,146,235],"to":[73,110,123,151,158,181,208,220,237,240,253,261,282],"expression":[76],"other":[78,174],"genes":[79],"through":[80],"sponging":[81],"micro":[82],"(miRNAs)":[84],"diseases.":[86,210,230,247,287],"This":[87],"mechanism,":[88],"known":[89],"as":[90,192],"competing":[92],"endogenous":[93],"(ceRNA)":[95],"hypothesis,":[96,215],"additional":[98],"information":[99],"obtained":[100],"from":[101,128,225],"datasets":[103],"be":[105],"used":[106,252],"by":[107],"computational":[108],"approaches":[109],"predict":[111,159,182,262,283],"novel":[112,154,183,205,263],"associations":[113,285,298],"between":[114],"disease":[115],"circRNAs.":[117],"RESULTS:":[118],"We":[119,177],"applied":[120,236],"classifiers":[122],"validate":[124],"extracted":[126,249],"features":[127,250],"heterogeneous":[130,223],"network":[131,224,239],"selected":[133],"most":[135],"appropriate":[136],"one":[137],"based":[138],"on":[139],"some":[140],"evaluation":[141],"criteria.":[142],"Then,":[143],"XGBoost":[145],"utilized":[147],"our":[149,200],"pipeline":[150],"generate":[152,258],"approach,":[155],"CircWalk,":[157],"CircRNA-Disease":[160,264,297],"associations.":[161,265],"Our":[162,266,288],"results":[163,197,289],"demonstrate":[164],"CircWalk":[166,180],"has":[167],"reasonable":[168],"accuracy":[169],"AUC":[171],"compared":[172],"state-of-the-art":[175],"algorithms.":[176],"also":[178],"use":[179],"associated":[185],"lung,":[187],"gastric,":[188],"colorectal":[190],"cancers":[191],"case":[194],"study.":[195],"The":[196,248],"show":[198,290],"approach":[201,267],"accurately":[203],"detect":[204],"related":[207],"these":[209],"CONCLUSIONS:":[211],"Considering":[212],"ceRNA":[214,273],"we":[216],"integrate":[217],"resources":[219],"construct":[221],"circRNAs,":[226],"mRNAs,":[227],"miRNAs,":[228],"Next,":[231],"DeepWalk":[233],"algorithm":[234],"extract":[241],"feature":[242],"vectors":[243],"learn":[254],"classifier":[256],"model":[260],"uses":[268],"concept":[270],"hypothesis":[274],"miRNA":[277],"sponge":[278],"effect":[279],"their":[284],"this":[292],"outlook":[293],"could":[294],"help":[295],"identify":[296],"more":[299],"accurately.":[300]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}