{"id":"https://openalex.org/W4283706978","doi":"https://doi.org/10.1186/s12859-022-04789-6","title":"Hyb4mC: a hybrid DNA2vec-based model for DNA N4-methylcytosine sites prediction","display_name":"Hyb4mC: a hybrid DNA2vec-based model for DNA N4-methylcytosine sites prediction","publication_year":2022,"publication_date":"2022-06-29","ids":{"openalex":"https://openalex.org/W4283706978","doi":"https://doi.org/10.1186/s12859-022-04789-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/35768759"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-022-04789-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04789-6","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04789-6","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04789-6","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085126930","display_name":"Ying Liang","orcid":"https://orcid.org/0000-0001-9092-2110"},"institutions":[{"id":"https://openalex.org/I74837319","display_name":"Jiangxi Agricultural University","ror":"https://ror.org/00dc7s858","country_code":"CN","type":"education","lineage":["https://openalex.org/I74837319"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ying Liang","raw_affiliation_strings":["College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China. aliang1229@126.com","College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China"],"affiliations":[{"raw_affiliation_string":"College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China. aliang1229@126.com","institution_ids":[]},{"raw_affiliation_string":"College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China","institution_ids":["https://openalex.org/I74837319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101603245","display_name":"Yanan Wu","orcid":"https://orcid.org/0000-0002-5611-2285"},"institutions":[{"id":"https://openalex.org/I74837319","display_name":"Jiangxi Agricultural University","ror":"https://ror.org/00dc7s858","country_code":"CN","type":"education","lineage":["https://openalex.org/I74837319"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanan Wu","raw_affiliation_strings":["College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China"],"affiliations":[{"raw_affiliation_string":"College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China","institution_ids":["https://openalex.org/I74837319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101810353","display_name":"Zequn Zhang","orcid":"https://orcid.org/0000-0002-8158-6562"},"institutions":[{"id":"https://openalex.org/I74837319","display_name":"Jiangxi Agricultural University","ror":"https://ror.org/00dc7s858","country_code":"CN","type":"education","lineage":["https://openalex.org/I74837319"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zequn Zhang","raw_affiliation_strings":["College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China"],"affiliations":[{"raw_affiliation_string":"College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China","institution_ids":["https://openalex.org/I74837319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103029518","display_name":"Niannian Liu","orcid":"https://orcid.org/0000-0002-0525-8698"},"institutions":[{"id":"https://openalex.org/I74837319","display_name":"Jiangxi Agricultural University","ror":"https://ror.org/00dc7s858","country_code":"CN","type":"education","lineage":["https://openalex.org/I74837319"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Niannian Liu","raw_affiliation_strings":["College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China"],"affiliations":[{"raw_affiliation_string":"College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China","institution_ids":["https://openalex.org/I74837319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001508531","display_name":"Jun Peng","orcid":"https://orcid.org/0000-0001-6188-731X"},"institutions":[{"id":"https://openalex.org/I74837319","display_name":"Jiangxi Agricultural University","ror":"https://ror.org/00dc7s858","country_code":"CN","type":"education","lineage":["https://openalex.org/I74837319"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Peng","raw_affiliation_strings":["College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China"],"affiliations":[{"raw_affiliation_string":"College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China","institution_ids":["https://openalex.org/I74837319"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047242215","display_name":"Jianjun Tang","orcid":"https://orcid.org/0000-0002-6994-2093"},"institutions":[{"id":"https://openalex.org/I74837319","display_name":"Jiangxi Agricultural University","ror":"https://ror.org/00dc7s858","country_code":"CN","type":"education","lineage":["https://openalex.org/I74837319"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianjun Tang","raw_affiliation_strings":["College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China"],"affiliations":[{"raw_affiliation_string":"College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang, China","institution_ids":["https://openalex.org/I74837319"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5085126930"],"corresponding_institution_ids":["https://openalex.org/I74837319"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":2.4265,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.89843364,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"23","issue":"1","first_page":"258","last_page":"258"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.991599977016449,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9865000247955322,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/5-methylcytosine","display_name":"5-Methylcytosine","score":0.6775200366973877},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.6344214677810669},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.565528154373169},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4783027768135071},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.44771072268486023},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.44182446599006653},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.34603333473205566},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3289739191532135},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.15523135662078857},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.06543081998825073}],"concepts":[{"id":"https://openalex.org/C2775926025","wikidata":"https://www.wikidata.org/wiki/Q238563","display_name":"5-Methylcytosine","level":5,"score":0.6775200366973877},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.6344214677810669},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.565528154373169},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4783027768135071},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.44771072268486023},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.44182446599006653},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34603333473205566},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3289739191532135},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15523135662078857},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.06543081998825073}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-022-04789-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04789-6","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04789-6","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:35768759","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35768759","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:46cf92342efd47a58c3df12324c504c8","is_oa":true,"landing_page_url":"https://doaj.org/article/46cf92342efd47a58c3df12324c504c8","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 23, Iss 1, Pp 1-18 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9241225","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9241225","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-022-04789-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04789-6","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04789-6","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1239594693","display_name":null,"funder_award_id":"62163018","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2626896578","display_name":null,"funder_award_id":"Grant Number:","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4283706978.pdf","grobid_xml":"https://content.openalex.org/works/W4283706978.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W2966661","https://openalex.org/W1577822803","https://openalex.org/W1715444199","https://openalex.org/W1890391421","https://openalex.org/W1981276685","https://openalex.org/W1984783889","https://openalex.org/W1993548347","https://openalex.org/W2006419303","https://openalex.org/W2014571977","https://openalex.org/W2038636394","https://openalex.org/W2046387526","https://openalex.org/W2084369308","https://openalex.org/W2093908800","https://openalex.org/W2123520920","https://openalex.org/W2137448281","https://openalex.org/W2152656267","https://openalex.org/W2156125289","https://openalex.org/W2537227711","https://openalex.org/W2579273737","https://openalex.org/W2737592062","https://openalex.org/W2810225085","https://openalex.org/W2883534252","https://openalex.org/W2891420113","https://openalex.org/W2939140832","https://openalex.org/W2942801317","https://openalex.org/W2945303443","https://openalex.org/W2946682182","https://openalex.org/W2952935243","https://openalex.org/W2967013910","https://openalex.org/W2976262693","https://openalex.org/W2987660980","https://openalex.org/W2993513714","https://openalex.org/W2998259324","https://openalex.org/W3004529363","https://openalex.org/W3007033512","https://openalex.org/W3011537067","https://openalex.org/W3015957975","https://openalex.org/W3034527519","https://openalex.org/W3037668068","https://openalex.org/W3114447330","https://openalex.org/W3116604690","https://openalex.org/W3136592363","https://openalex.org/W3154540177","https://openalex.org/W3195367207","https://openalex.org/W3198147676","https://openalex.org/W4200111237","https://openalex.org/W4200144569","https://openalex.org/W4244895750","https://openalex.org/W4252758873","https://openalex.org/W6610017368"],"related_works":["https://openalex.org/W3189610884","https://openalex.org/W2476700496","https://openalex.org/W2050354664","https://openalex.org/W2968854070","https://openalex.org/W2256800217","https://openalex.org/W2358488663","https://openalex.org/W2916127307","https://openalex.org/W2045389794","https://openalex.org/W1979814181","https://openalex.org/W1981064236"],"abstract_inverted_index":{"Extensive":[0],"benchmark":[1],"tests":[2],"have":[3],"shown":[4],"that":[5],"Hyb4mC":[6],"can":[7],"significantly":[8],"enhance":[9],"the":[10,18],"performance":[11],"of":[12],"predicting":[13],"4mC":[14],"sites":[15],"compared":[16],"with":[17],"recently":[19],"proposed":[20],"methods.":[21]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":4}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}