{"id":"https://openalex.org/W4282925451","doi":"https://doi.org/10.1186/s12859-022-04735-6","title":"A successful hybrid deep learning model aiming at promoter identification","display_name":"A successful hybrid deep learning model aiming at promoter identification","publication_year":2022,"publication_date":"2022-05-31","ids":{"openalex":"https://openalex.org/W4282925451","doi":"https://doi.org/10.1186/s12859-022-04735-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/35641900"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-022-04735-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04735-6","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04735-6","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04735-6","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091086245","display_name":"Ying Wang","orcid":"https://orcid.org/0000-0002-8713-417X"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Wang","raw_affiliation_strings":["Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074144985","display_name":"Qinke Peng","orcid":"https://orcid.org/0000-0002-5448-8529"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qinke Peng","raw_affiliation_strings":["Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China. qkpeng@xjtu.edu.cn","Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China. qkpeng@xjtu.edu.cn","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112978609","display_name":"Mou Xu","orcid":"https://orcid.org/0000-0002-1497-0572"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xu Mou","raw_affiliation_strings":["Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100634221","display_name":"Xinyuan Wang","orcid":"https://orcid.org/0009-0006-8330-342X"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinyuan Wang","raw_affiliation_strings":["Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057848410","display_name":"Haozhou Li","orcid":"https://orcid.org/0009-0001-0955-470X"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haozhou Li","raw_affiliation_strings":["Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100692759","display_name":"Tian Han","orcid":"https://orcid.org/0009-0008-7118-0500"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tian Han","raw_affiliation_strings":["Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100660513","display_name":"Zhao Sun","orcid":"https://orcid.org/0000-0001-6083-593X"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhao Sun","raw_affiliation_strings":["Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100411464","display_name":"Xiao Wang","orcid":"https://orcid.org/0000-0002-3113-5149"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao Wang","raw_affiliation_strings":["Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Engineering Institute, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5074144985"],"corresponding_institution_ids":["https://openalex.org/I87445476"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":1.2536,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.78376751,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"23","issue":"S1","first_page":"206","last_page":"206"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.8802000284194946,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.8802000284194946,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.1062999963760376,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/promoter","display_name":"Promoter","score":0.9374899864196777},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6321663856506348},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.47417008876800537},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.47244933247566223},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.42604780197143555},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.32151514291763306},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.31229689717292786},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.14082947373390198}],"concepts":[{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.9374899864196777},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6321663856506348},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.47417008876800537},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47244933247566223},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.42604780197143555},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32151514291763306},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.31229689717292786},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.14082947373390198}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024363","descriptor_name":"Transcription Initiation Site","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024363","descriptor_name":"Transcription Initiation Site","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024363","descriptor_name":"Transcription Initiation Site","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048168","descriptor_name":"Escherichia coli K12","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D048168","descriptor_name":"Escherichia coli K12","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D048168","descriptor_name":"Escherichia coli K12","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-022-04735-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04735-6","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04735-6","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:35641900","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35641900","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:a99278ec26bc404ba5efa420cfa07a4f","is_oa":true,"landing_page_url":"https://doaj.org/article/a99278ec26bc404ba5efa420cfa07a4f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 23, Iss S1, Pp 1-21 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9158169","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9158169","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-022-04735-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04735-6","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04735-6","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7300000190734863,"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities"}],"awards":[{"id":"https://openalex.org/G996507653","display_name":"\u57fa\u4e8e\u6df1\u5ea6\u5b66\u4e60\u7684miRNA\u3001lncRNA\u548ccircRNA\u5173\u7cfb\u5206\u6790\u53ca\u5176\u4e0e\u4eba\u7c7b\u590d\u6742\u6027\u75be\u75c5\u5173\u8054\u6027\u7814\u7a76","funder_award_id":"61872288","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4282925451.pdf","grobid_xml":"https://content.openalex.org/works/W4282925451.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W1531710418","https://openalex.org/W1605738254","https://openalex.org/W1969686829","https://openalex.org/W1978643997","https://openalex.org/W2009095852","https://openalex.org/W2031123552","https://openalex.org/W2051434262","https://openalex.org/W2056422388","https://openalex.org/W2063534876","https://openalex.org/W2086896720","https://openalex.org/W2090708401","https://openalex.org/W2095994064","https://openalex.org/W2097117768","https://openalex.org/W2097920884","https://openalex.org/W2098442797","https://openalex.org/W2099728493","https://openalex.org/W2101163218","https://openalex.org/W2107578440","https://openalex.org/W2111400482","https://openalex.org/W2116060321","https://openalex.org/W2122277359","https://openalex.org/W2124266758","https://openalex.org/W2129656350","https://openalex.org/W2130200358","https://openalex.org/W2142784993","https://openalex.org/W2143726250","https://openalex.org/W2148114118","https://openalex.org/W2163605009","https://openalex.org/W2164604555","https://openalex.org/W2167865654","https://openalex.org/W2169351355","https://openalex.org/W2194775991","https://openalex.org/W2198606573","https://openalex.org/W2232370058","https://openalex.org/W2308360327","https://openalex.org/W2320044977","https://openalex.org/W2512780338","https://openalex.org/W2520774990","https://openalex.org/W2578051997","https://openalex.org/W2580767461","https://openalex.org/W2585635281","https://openalex.org/W2754289562","https://openalex.org/W2768083292","https://openalex.org/W2810754857","https://openalex.org/W2909409778","https://openalex.org/W2909854604","https://openalex.org/W2932524182","https://openalex.org/W2945472816","https://openalex.org/W2950758817","https://openalex.org/W2952802059","https://openalex.org/W2963739921","https://openalex.org/W2969556351","https://openalex.org/W2996274328","https://openalex.org/W2998840182","https://openalex.org/W6673372182","https://openalex.org/W6685197303","https://openalex.org/W6713955831","https://openalex.org/W7073846088"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W1969771092","https://openalex.org/W2795723184","https://openalex.org/W2025529750","https://openalex.org/W2891858816","https://openalex.org/W184057646","https://openalex.org/W2042874675","https://openalex.org/W129398428","https://openalex.org/W3212414177","https://openalex.org/W1975811142"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,174,241,285],"zone":[2],"adjacent":[3],"to":[4,58,75,121,145,157,168,178,290],"a":[5,26,93,123,142],"transcription":[6,21],"start":[7],"site":[8],"(TSS),":[9],"namely,":[10],"the":[11,17,36,39,49,59,65,86,102,108,114,119,126,147,159,188,192,198,201,206,213,224,245,251,258,270,297],"promoter,":[12],"is":[13,31,154,287],"primarily":[14],"involved":[15],"in":[16,63,161,231],"process":[18],"of":[19,38,46,51,67,105,111,163,200,215,234,253,260,279,299],"DNA":[20],"initiation":[22],"and":[23,80,107,137,167,181,187,220,266,269],"regulation.":[24,43],"As":[25],"result,":[27],"proper":[28],"promoter":[29,90,135,202,207,238,283],"identification":[30,50,91,208],"critical":[32],"for":[33,48,89,296],"further":[34],"understanding":[35],"mechanism":[37],"networks":[40],"controlling":[41],"genomic":[42],"A":[44],"number":[45],"methodologies":[47],"promoters":[52,106,112,160,235,254,262,280],"have":[53],"been":[54],"proposed.":[55],"Nonetheless,":[56],"due":[57],"great":[60],"heterogeneity":[61],"existing":[62],"promoters,":[64,83],"results":[66,230,242],"these":[68],"procedures":[69],"are":[70,274],"still":[71],"unsatisfactory.":[72],"In":[73,210],"order":[74],"establish":[76],"additional":[77],"discriminative":[78],"characteristics":[79],"properly":[81],"recognize":[82],"we":[84],"developed":[85,118],"hybrid":[87,94],"model":[88,97,158],"(HMPI),":[92],"deep":[95],"learning":[96,219],"that":[98,191,244],"can":[99],"characterize":[100],"both":[101,264],"native":[103,134],"sequences":[104,136],"morphological":[109],"outline":[110],"at":[113,196,249,276],"same":[115],"time.":[116],"We":[117],"HMPI":[120,175,193,226,246,272,286],"combine":[122],"method":[124],"called":[125],"PSFN":[127],"(promoter":[128],"sequence":[129,139],"features":[130,199,252,301],"network),":[131,152],"which":[132,153],"characterizes":[133],"deduces":[138],"features,":[140],"with":[141],"technique":[143],"referred":[144],"as":[146],"DSPN":[148],"(deep":[149],"structural":[150,165,171],"profiles":[151],"specially":[155],"structured":[156],"terms":[162],"their":[164,170],"profile":[166],"deduce":[169],"attributes.":[172],"RESULTS:":[173],"was":[176,194,247],"applied":[177],"human,":[179],"plant":[180],"Escherichia":[182],"coli":[183],"K-12":[184],"strain":[185],"datasets,":[186,268],"findings":[189],"showed":[190,243],"successful":[195,248],"extracting":[197,250],"while":[203,255],"greatly":[204,256],"enhancing":[205,257],"performance.":[209],"addition,":[211],"after":[212],"improvements":[214],"synthetic":[216],"sampling,":[217],"transfer":[218],"label":[221],"smoothing":[222],"regularization,":[223],"improved":[225,271],"models":[227,273],"achieved":[228],"good":[229,275],"identifying":[232,261,277],"subtypes":[233,278],"on":[236,263,281],"prokaryotic":[237,267,282],"datasets.":[239,284],"CONCLUSIONS:":[240],"performance":[259],"eukaryotic":[265],"additionally":[288],"adaptable":[289],"different":[291],"biological":[292],"functional":[293],"sequences,":[294],"allowing":[295],"addition":[298],"new":[300],"or":[302],"models.":[303]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":7}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}