{"id":"https://openalex.org/W4224325451","doi":"https://doi.org/10.1186/s12859-022-04682-2","title":"CoMI: consensus mutual information for tissue-specific gene signatures","display_name":"CoMI: consensus mutual information for tissue-specific gene signatures","publication_year":2021,"publication_date":"2021-05-01","ids":{"openalex":"https://openalex.org/W4224325451","doi":"https://doi.org/10.1186/s12859-022-04682-2","pmid":"https://pubmed.ncbi.nlm.nih.gov/35439942"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-022-04682-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04682-2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-022-04682-2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-022-04682-2","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054545929","display_name":"Sing\u2010Han Huang","orcid":"https://orcid.org/0000-0003-0289-2260"},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Sing-Han Huang","raw_affiliation_strings":["Graphen Inc., New York, NY, 10110, USA","Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan","Graphen Inc., New York, USA","Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graphen Inc., New York, NY, 10110, USA","institution_ids":[]},{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Graphen Inc., New York, USA","institution_ids":[]},{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103865488","display_name":"Yu\u2010Shu Lo","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yu-Shu Lo","raw_affiliation_strings":["Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan","Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018441181","display_name":"Yong-Chun Luo","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yong-Chun Luo","raw_affiliation_strings":["Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan","Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014996213","display_name":"Yi\u2010Hsuan Chuang","orcid":"https://orcid.org/0000-0002-1351-4305"},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yi-Hsuan Chuang","raw_affiliation_strings":["Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan","Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110850878","display_name":"Jung-Yu Lee","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jung-Yu Lee","raw_affiliation_strings":["Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan","Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088590993","display_name":"Jinn\u2010Moon Yang","orcid":"https://orcid.org/0000-0002-3205-4391"},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Jinn-Moon Yang","raw_affiliation_strings":["Center for Intelligent Drug Systems and Smart Bio-Devices, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan. moon@faculty.nctu.edu.tw","Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan. moon@faculty.nctu.edu.tw","Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan. moon@faculty.nctu.edu.tw","Center for Intelligent Drug Systems and Smart Bio-Devices, National Yang Ming Chiao Tung University, Hsinchu, Taiwan","Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan","Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan"],"raw_orcid":"https://orcid.org/0000-0002-3205-4391","affiliations":[{"raw_affiliation_string":"Center for Intelligent Drug Systems and Smart Bio-Devices, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan. moon@faculty.nctu.edu.tw","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan. moon@faculty.nctu.edu.tw","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, 300193, Taiwan. moon@faculty.nctu.edu.tw","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Center for Intelligent Drug Systems and Smart Bio-Devices, National Yang Ming Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5088590993"],"corresponding_institution_ids":["https://openalex.org/I148366613"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14706587,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"22","issue":"S10","first_page":"624","last_page":"624"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.6186000108718872,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.6186000108718872,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.1589999943971634,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.07880000025033951,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.705742597579956},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5946747064590454},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.5633059144020081},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.530424177646637},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5269359350204468},{"id":"https://openalex.org/keywords/gene-signature","display_name":"Gene signature","score":0.5007359981536865},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.489238977432251},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.42618608474731445},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.32174256443977356},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.21738958358764648},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.172836035490036},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.12080603837966919}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.705742597579956},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5946747064590454},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.5633059144020081},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.530424177646637},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5269359350204468},{"id":"https://openalex.org/C2779733811","wikidata":"https://www.wikidata.org/wiki/Q5531562","display_name":"Gene signature","level":4,"score":0.5007359981536865},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.489238977432251},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.42618608474731445},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.32174256443977356},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21738958358764648},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.172836035490036},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12080603837966919}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032921","descriptor_name":"Consensus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032921","descriptor_name":"Consensus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032921","descriptor_name":"Consensus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-022-04682-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04682-2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-022-04682-2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:35439942","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35439942","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:765db4176cea43ac8806f7b5d5a40d30","is_oa":true,"landing_page_url":"https://doaj.org/article/765db4176cea43ac8806f7b5d5a40d30","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 22, Iss S10, Pp 1-18 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9019939","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9019939","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-022-04682-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-022-04682-2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-022-04682-2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7900000214576721,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1198904040","display_name":null,"funder_award_id":"IDS2B","funder_id":"https://openalex.org/F4320323443","funder_display_name":"National Chiao Tung University"},{"id":"https://openalex.org/G1574904773","display_name":null,"funder_award_id":"MOST 109-2634-F-009-021","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"},{"id":"https://openalex.org/G5773229215","display_name":null,"funder_award_id":"MOST 109-2321-B-009-007","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"},{"id":"https://openalex.org/G7086522080","display_name":null,"funder_award_id":"NHRI-EX109-10504PI","funder_id":"https://openalex.org/F4320322845","funder_display_name":"National Health Research Institutes"}],"funders":[{"id":"https://openalex.org/F4320321528","display_name":"Shanghai Educational Development Foundation","ror":"https://ror.org/0220qvk04"},{"id":"https://openalex.org/F4320322724","display_name":"Ministry of Education, India","ror":"https://ror.org/048xjjh50"},{"id":"https://openalex.org/F4320322795","display_name":"Ministry of Science and Technology, Taiwan","ror":"https://ror.org/02kv4zf79"},{"id":"https://openalex.org/F4320322845","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29"},{"id":"https://openalex.org/F4320323443","display_name":"National Chiao Tung University","ror":"https://ror.org/00se2k293"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4224325451.pdf","grobid_xml":"https://content.openalex.org/works/W4224325451.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1107917109","https://openalex.org/W1254161066","https://openalex.org/W1554196337","https://openalex.org/W2006873092","https://openalex.org/W2012034410","https://openalex.org/W2022240786","https://openalex.org/W2025915824","https://openalex.org/W2044702943","https://openalex.org/W2081436697","https://openalex.org/W2097255042","https://openalex.org/W2098734857","https://openalex.org/W2117692326","https://openalex.org/W2121158863","https://openalex.org/W2132619562","https://openalex.org/W2133210805","https://openalex.org/W2138550913","https://openalex.org/W2139290043","https://openalex.org/W2144267973","https://openalex.org/W2146512944","https://openalex.org/W2154061034","https://openalex.org/W2157795344","https://openalex.org/W2158485828","https://openalex.org/W2259802687","https://openalex.org/W2528569964","https://openalex.org/W2949475756","https://openalex.org/W2952849701","https://openalex.org/W2991368735","https://openalex.org/W4294107304"],"related_works":["https://openalex.org/W2415545834","https://openalex.org/W2069695727","https://openalex.org/W106077234","https://openalex.org/W2041374557","https://openalex.org/W2081929287","https://openalex.org/W2144348650","https://openalex.org/W2132561013","https://openalex.org/W1994852842","https://openalex.org/W4246178523","https://openalex.org/W1902990570"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1],"gene":[2,25,55,67,86,160,185],"signatures":[3,26,56,130,161,186],"have":[4,50],"been":[5,51],"considered":[6],"as":[7,107],"a":[8,28,73],"promising":[9],"early":[10],"diagnosis":[11,58,146],"and":[12,19,42,59,84,103,110,117,121,138,147,158,165,183],"prognostic":[13],"analysis":[14],"to":[15,20,38],"identify":[16,90,156],"disease":[17,30],"subtypes":[18],"determine":[21],"subsequent":[22],"treatments.":[23],"Tissue-specific":[24],"of":[27,65,187],"specific":[29],"are":[31],"an":[32],"emergency":[33],"requirement":[34],"for":[35,53,57,80,99,145,170,179],"precision":[36],"medicine":[37],"improve":[39],"the":[40,44,133],"accuracy":[41],"reduce":[43],"side":[45],"effects.":[46],"Currently,":[47],"many":[48],"approaches":[49],"proposed":[52],"identifying":[54],"prognostic.":[60],"However,":[61],"they":[62],"often":[63],"lack":[64],"tissue-specific":[66,104,163],"signatures.":[68,87],"RESULTS:":[69],"Here,":[70],"we":[71],"propose":[72],"new":[74],"method,":[75],"consensus":[76],"mutual":[77],"information":[78],"(CoMI)":[79],"analyzing":[81,180],"omics":[82,97,181],"data":[83,98,182],"discovering":[85,184],"CoMI":[88,154,176],"can":[89,155,166],"differentially":[91],"expressed":[92],"genes":[93],"in":[94,112,119,124],"multiple":[95,113],"cancer":[96],"reflecting":[100],"both":[101],"cancer-related":[102],"signatures,":[105],"such":[106],"Cell":[108],"growth":[109],"death":[111],"cancers,":[114],"Xenobiotics":[115],"biodegradation":[116],"metabolism":[118],"LIHC,":[120],"Nervous":[122],"system":[123],"GBM.":[125],"Our":[126,150],"method":[127],"identified":[128],"50-gene":[129],"effectively":[131],"distinguishing":[132],"GBM":[134],"patients":[135],"into":[136],"high-":[137],"low-risk":[139],"groups":[140],"(log-rank":[141],"p":[142],"=":[143],"0.006)":[144],"prognosis.":[148],"CONCLUSIONS:":[149],"results":[151],"demonstrate":[152],"that":[153,175],"significant":[157],"consistent":[159],"with":[162],"properties":[164],"predict":[167],"clinical":[168],"outcomes":[169],"interested":[171],"diseases.":[172,188],"We":[173],"believe":[174],"is":[177],"useful":[178]},"counts_by_year":[],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}