{"id":"https://openalex.org/W3129518246","doi":"https://doi.org/10.1186/s12859-021-04016-8","title":"CANTARE: finding and visualizing network-based multi-omic predictive models","display_name":"CANTARE: finding and visualizing network-based multi-omic predictive models","publication_year":2021,"publication_date":"2021-02-19","ids":{"openalex":"https://openalex.org/W3129518246","doi":"https://doi.org/10.1186/s12859-021-04016-8","mag":"3129518246","pmid":"https://pubmed.ncbi.nlm.nih.gov/33607938"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-021-04016-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-021-04016-8","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-021-04016-8","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-021-04016-8","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084490246","display_name":"Janet Siebert","orcid":"https://orcid.org/0000-0001-8505-9359"},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz Medical Campus","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Janet C. Siebert","raw_affiliation_strings":["Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. jsiebert@cytoanalytics.com","Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. jsiebert@cytoanalytics.com","institution_ids":["https://openalex.org/I51713134"]},{"raw_affiliation_string":"Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015808445","display_name":"Martine Saint-Cyr","orcid":null},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz Medical Campus","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martine Saint-Cyr","raw_affiliation_strings":["Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072786470","display_name":"Sarah J. Borengasser","orcid":"https://orcid.org/0000-0002-9984-0178"},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz Medical Campus","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah J. Borengasser","raw_affiliation_strings":["Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072220989","display_name":"Brandie D. Wagner","orcid":"https://orcid.org/0000-0002-2745-0103"},"institutions":[{"id":"https://openalex.org/I151808059","display_name":"Colorado School of Public Health","ror":"https://ror.org/005x9g035","country_code":"US","type":"education","lineage":["https://openalex.org/I151808059"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brandie D. Wagner","raw_affiliation_strings":["Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO, USA","institution_ids":["https://openalex.org/I151808059"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086938254","display_name":"Catherine Lozupone","orcid":"https://orcid.org/0000-0003-4786-7202"},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz Medical Campus","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Catherine A. Lozupone","raw_affiliation_strings":["Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064020522","display_name":"Carsten G\u00f6rg","orcid":"https://orcid.org/0000-0001-5088-4201"},"institutions":[{"id":"https://openalex.org/I151808059","display_name":"Colorado School of Public Health","ror":"https://ror.org/005x9g035","country_code":"US","type":"education","lineage":["https://openalex.org/I151808059"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carsten G\u00f6rg","raw_affiliation_strings":["Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO, USA","institution_ids":["https://openalex.org/I151808059"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5084490246"],"corresponding_institution_ids":["https://openalex.org/I51713134"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":0.5921,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.62626068,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"22","issue":"1","first_page":"80","last_page":"80"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.7653999924659729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.7653999924659729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13283","display_name":"Mental Health Research Topics","score":0.11330000311136246,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T14393","display_name":"Health, Environment, Cognitive Aging","score":0.019500000402331352,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.7824018001556396},{"id":"https://openalex.org/keywords/pairwise-comparison","display_name":"Pairwise comparison","score":0.6979578733444214},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5825302004814148},{"id":"https://openalex.org/keywords/regression","display_name":"Regression","score":0.5610074400901794},{"id":"https://openalex.org/keywords/metagenomics","display_name":"Metagenomics","score":0.5260144472122192},{"id":"https://openalex.org/keywords/predictive-modelling","display_name":"Predictive modelling","score":0.5208490490913391},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5059196352958679},{"id":"https://openalex.org/keywords/logistic-regression","display_name":"Logistic regression","score":0.49622637033462524},{"id":"https://openalex.org/keywords/regression-analysis","display_name":"Regression analysis","score":0.4697326123714447},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.45492616295814514},{"id":"https://openalex.org/keywords/predictive-value","display_name":"Predictive value","score":0.41943567991256714},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4143711030483246},{"id":"https://openalex.org/keywords/predictive-analytics","display_name":"Predictive analytics","score":0.4141484797000885},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.32342708110809326},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.23159846663475037},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.20857647061347961},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.12396731972694397}],"concepts":[{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.7824018001556396},{"id":"https://openalex.org/C184898388","wikidata":"https://www.wikidata.org/wiki/Q1435712","display_name":"Pairwise comparison","level":2,"score":0.6979578733444214},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5825302004814148},{"id":"https://openalex.org/C83546350","wikidata":"https://www.wikidata.org/wiki/Q1139051","display_name":"Regression","level":2,"score":0.5610074400901794},{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.5260144472122192},{"id":"https://openalex.org/C45804977","wikidata":"https://www.wikidata.org/wiki/Q7239673","display_name":"Predictive modelling","level":2,"score":0.5208490490913391},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5059196352958679},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.49622637033462524},{"id":"https://openalex.org/C152877465","wikidata":"https://www.wikidata.org/wiki/Q208042","display_name":"Regression analysis","level":2,"score":0.4697326123714447},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.45492616295814514},{"id":"https://openalex.org/C3019719930","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value","level":2,"score":0.41943567991256714},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4143711030483246},{"id":"https://openalex.org/C83209312","wikidata":"https://www.wikidata.org/wiki/Q1053367","display_name":"Predictive analytics","level":2,"score":0.4141484797000885},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.32342708110809326},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.23159846663475037},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20857647061347961},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12396731972694397},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-021-04016-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-021-04016-8","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-021-04016-8","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:33607938","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33607938","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:bc289711b138499aa3088275ca420460","is_oa":true,"landing_page_url":"https://doaj.org/article/bc289711b138499aa3088275ca420460","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 22, Iss 1, Pp 1-21 (2021)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7896366","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7896366","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-021-04016-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-021-04016-8","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-021-04016-8","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Life in Land","score":0.5400000214576721,"id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G2875898119","display_name":"EPIGENETIC AND MICROBIOME RESPONSES TO A WEIGHT LOSS INTERVENTION","funder_award_id":"18IPA34170317","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G3549828030","display_name":null,"funder_award_id":"NIH T32","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G69684329","display_name":null,"funder_award_id":"T32 DK007658","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3129518246.pdf","grobid_xml":"https://content.openalex.org/works/W3129518246.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W1554944419","https://openalex.org/W1915598702","https://openalex.org/W1981127801","https://openalex.org/W2085852125","https://openalex.org/W2105857910","https://openalex.org/W2122825543","https://openalex.org/W2127543426","https://openalex.org/W2129690444","https://openalex.org/W2131026689","https://openalex.org/W2155860422","https://openalex.org/W2215242224","https://openalex.org/W2283969854","https://openalex.org/W2306754445","https://openalex.org/W2315613727","https://openalex.org/W2460803411","https://openalex.org/W2507679967","https://openalex.org/W2524172848","https://openalex.org/W2567080747","https://openalex.org/W2576359618","https://openalex.org/W2597605420","https://openalex.org/W2611418622","https://openalex.org/W2614653414","https://openalex.org/W2663374310","https://openalex.org/W2744843809","https://openalex.org/W2768361988","https://openalex.org/W2792954251","https://openalex.org/W2802297432","https://openalex.org/W2802863404","https://openalex.org/W2809990446","https://openalex.org/W2883846150","https://openalex.org/W2897713201","https://openalex.org/W2899852374","https://openalex.org/W2903406988","https://openalex.org/W2907177946","https://openalex.org/W2908775210","https://openalex.org/W2909668868","https://openalex.org/W2911964244","https://openalex.org/W2919677611","https://openalex.org/W2945725681","https://openalex.org/W2949667594","https://openalex.org/W2951124970","https://openalex.org/W2960606948","https://openalex.org/W2969259411","https://openalex.org/W2975959480","https://openalex.org/W2989827860","https://openalex.org/W2994890869","https://openalex.org/W3002468962","https://openalex.org/W3007062597","https://openalex.org/W3034996730","https://openalex.org/W3093849869","https://openalex.org/W3142822121","https://openalex.org/W3143077622","https://openalex.org/W3175417087"],"related_works":["https://openalex.org/W3108868229","https://openalex.org/W4205686051","https://openalex.org/W4206275624","https://openalex.org/W3189884647","https://openalex.org/W4313451520","https://openalex.org/W3134571208","https://openalex.org/W3203664106","https://openalex.org/W4251864566","https://openalex.org/W4224092800","https://openalex.org/W2910942700"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"One":[2],"goal":[3],"of":[4,15,79,108,118,136,145,170,191,205,243,350],"multi-omic":[5,97,334],"studies":[6],"is":[7],"to":[8,40,63,155,199,207,266],"identify":[9],"interpretable":[10,77,333],"predictive":[11,90,126,183,283,302],"models":[12,92,104,129,184,195,237,261,284,291,303,337],"for":[13,74,88,296,330,344,352],"outcomes":[14],"interest,":[16],"with":[17,164,185,224,292],"analytes":[18,109,132],"drawn":[19],"from":[20,49,93,110,159,197,269,285,305],"multiple":[21,270],"omes.":[22,60],"Such":[23],"findings":[24],"could":[25],"support":[26,347],"refined":[27],"biological":[28],"insight":[29],"and":[30,55,76,162,176,210,217,230,250,314,340,346],"hypothesis":[31],"generation.":[32],"However,":[33],"standard":[34],"analytical":[35],"approaches":[36],"are":[37,319],"not":[38],"designed":[39],"be":[41],"\u201come":[42],"aware.\u201d":[43],"Thus,":[44],"some":[45],"researchers":[46],"analyze":[47],"data":[48,158],"one":[50],"ome":[51],"at":[52,321],"a":[53,85,121,239,286,306,315,327],"time,":[54],"then":[56],"combine":[57],"predictions":[58],"across":[59,105],"Others":[61],"resort":[62],"correlation":[64,307],"studies,":[65],"cataloging":[66],"pairwise":[67,102,290],"relationships,":[68],"but":[69],"lacking":[70],"an":[71,293],"obvious":[72],"approach":[73,329],"cohesive":[75],"summaries":[78],"these":[80,194],"catalogs.":[81],"Methods":[82],"We":[83,138,152,179,201,279],"present":[84],"novel":[86],"workflow":[87],"building":[89,331],"regression":[91,103,128],"network":[94,134,287,308],"neighborhoods":[95,135],"in":[96,120,133,193],"networks.":[98],"First,":[99],"we":[100,124],"generate":[101],"all":[106,111],"pairs":[107],"omes,":[112],"encoding":[113],"the":[114,131,203,274,348],"resulting":[115],"\u201ctop":[116],"table\u201d":[117],"relationships":[119],"network.":[122],"Then,":[123],"build":[125],"logistic":[127],"using":[130],"interest.":[137],"call":[139],"this":[140],"method":[141],"CANTARE":[142,154,206,219,236,260,316,325],"(Consolidated":[143],"Analysis":[144],"Network":[146],"Topology":[147],"And":[148],"Regression":[149],"Elements).":[150],"Results":[151],"applied":[153],"previously":[156],"published":[157],"healthy":[160],"controls":[161],"patients":[163],"inflammatory":[165],"bowel":[166],"disease":[167],"(IBD)":[168],"consisting":[169],"three":[171],"omes:":[172],"gut":[173],"microbiome,":[174],"metabolomics,":[175],"microbial-derived":[177],"enzymes.":[178],"identified":[180],"8":[181],"unique":[182],"AUC":[186,220,300],">":[187],"0.90.":[188],"The":[189,233],"number":[190],"predictors":[192,268,345],"ranged":[196],"3":[198,235],"13.":[200],"compare":[202],"results":[204],"random":[208,228,248],"forests":[209,229,249],"elastic-net":[211],"penalized":[212,231,251],"regressions,":[213],"analyzing":[214],"AUC,":[215],"predictions,":[216],"predictors.":[218],"values":[221],"were":[222,262,273],"competitive":[223],"those":[225],"generated":[226],"by":[227],"regressions.":[232],"top":[234],"had":[238],"greater":[240],"dynamic":[241],"range":[242],"predicted":[244],"probabilities":[245],"than":[246,272,301],"did":[247],"regressions":[252],"(p-value":[253,276,309],"=":[254,277,310],"1.35":[255],"\u00d7":[256],"10":[257],"\u20135":[258],").":[259],"significantly":[263],"more":[264],"likely":[265],"prioritize":[267],"omes":[271],"alternatives":[275],"0.005).":[278],"also":[280],"showed":[281],"that":[282],"based":[288],"on":[289],"interaction":[294],"term":[295],"IBD":[297],"have":[298],"higher":[299],"built":[304],"0.016).":[311],"R":[312],"scripts":[313],"User\u2019s":[317],"Guide":[318],"available":[320],"https://sourceforge.net/projects/cytomelodics/files/CANTARE/":[322],".":[323],"Conclusion":[324],"offers":[326],"flexible":[328],"parsimonious,":[332],"models.":[335],"These":[336],"yield":[338],"quantitative":[339],"directional":[341],"effect":[342],"sizes":[343],"generation":[349],"hypotheses":[351],"follow-up":[353],"investigation.":[354]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}