{"id":"https://openalex.org/W3112330887","doi":"https://doi.org/10.1186/s12859-020-03898-4","title":"Hybrid attentional memory network for computational drug repositioning","display_name":"Hybrid attentional memory network for computational drug repositioning","publication_year":2020,"publication_date":"2020-12-01","ids":{"openalex":"https://openalex.org/W3112330887","doi":"https://doi.org/10.1186/s12859-020-03898-4","mag":"3112330887","pmid":"https://pubmed.ncbi.nlm.nih.gov/33297947"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-020-03898-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-020-03898-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03898-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03898-4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101699117","display_name":"Jieyue He","orcid":"https://orcid.org/0000-0002-3265-3351"},"institutions":[{"id":"https://openalex.org/I76569877","display_name":"Southeast University","ror":"https://ror.org/04ct4d772","country_code":"CN","type":"education","lineage":["https://openalex.org/I76569877"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jieyue He","raw_affiliation_strings":["School of Computer Science and Engineering, Key Lab of Computer Network and Information Integration, MOE, Southeast University, Nanjing, 210018, China. jieyuehe@seu.edu.cn","School of Computer Science and Engineering, Key Lab of Computer Network and Information Integration, MOE, Southeast University, Nanjing, 210018, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Key Lab of Computer Network and Information Integration, MOE, Southeast University, Nanjing, 210018, China. jieyuehe@seu.edu.cn","institution_ids":[]},{"raw_affiliation_string":"School of Computer Science and Engineering, Key Lab of Computer Network and Information Integration, MOE, Southeast University, Nanjing, 210018, China","institution_ids":["https://openalex.org/I76569877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001741551","display_name":"Xinxing Yang","orcid":"https://orcid.org/0000-0002-1512-2970"},"institutions":[{"id":"https://openalex.org/I76569877","display_name":"Southeast University","ror":"https://ror.org/04ct4d772","country_code":"CN","type":"education","lineage":["https://openalex.org/I76569877"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinxing Yang","raw_affiliation_strings":["School of Computer Science and Engineering, Key Lab of Computer Network and Information Integration, MOE, Southeast University, Nanjing, 210018, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Key Lab of Computer Network and Information Integration, MOE, Southeast University, Nanjing, 210018, China","institution_ids":["https://openalex.org/I76569877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101454301","display_name":"Zhuo Gong","orcid":"https://orcid.org/0000-0002-7983-7764"},"institutions":[{"id":"https://openalex.org/I76569877","display_name":"Southeast University","ror":"https://ror.org/04ct4d772","country_code":"CN","type":"education","lineage":["https://openalex.org/I76569877"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuo Gong","raw_affiliation_strings":["School of Computer Science and Engineering, Key Lab of Computer Network and Information Integration, MOE, Southeast University, Nanjing, 210018, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Key Lab of Computer Network and Information Integration, MOE, Southeast University, Nanjing, 210018, China","institution_ids":["https://openalex.org/I76569877"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002802461","display_name":"lbrahim Zamit","orcid":null},"institutions":[{"id":"https://openalex.org/I76569877","display_name":"Southeast University","ror":"https://ror.org/04ct4d772","country_code":"CN","type":"education","lineage":["https://openalex.org/I76569877"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"lbrahim Zamit","raw_affiliation_strings":["School of Computer Science and Engineering, Key Lab of Computer Network and Information Integration, MOE, Southeast University, Nanjing, 210018, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Key Lab of Computer Network and Information Integration, MOE, Southeast University, Nanjing, 210018, China","institution_ids":["https://openalex.org/I76569877"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5101699117"],"corresponding_institution_ids":["https://openalex.org/I76569877"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.7219,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.77812646,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"21","issue":"1","first_page":"566","last_page":"566"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9908000230789185,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.7248531579971313},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6803242564201355},{"id":"https://openalex.org/keywords/drug-repositioning","display_name":"Drug repositioning","score":0.6451886892318726},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.6364693641662598},{"id":"https://openalex.org/keywords/autoencoder","display_name":"Autoencoder","score":0.5983339548110962},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5621659159660339},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.49369558691978455},{"id":"https://openalex.org/keywords/drug-target","display_name":"Drug target","score":0.43432727456092834},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.43247368931770325},{"id":"https://openalex.org/keywords/drug-development","display_name":"Drug development","score":0.41166165471076965},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.34892717003822327},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.31716471910476685},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.0995820164680481}],"concepts":[{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.7248531579971313},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6803242564201355},{"id":"https://openalex.org/C103637391","wikidata":"https://www.wikidata.org/wiki/Q5308921","display_name":"Drug repositioning","level":3,"score":0.6451886892318726},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.6364693641662598},{"id":"https://openalex.org/C101738243","wikidata":"https://www.wikidata.org/wiki/Q786435","display_name":"Autoencoder","level":3,"score":0.5983339548110962},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5621659159660339},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.49369558691978455},{"id":"https://openalex.org/C2989108626","wikidata":"https://www.wikidata.org/wiki/Q904407","display_name":"Drug target","level":2,"score":0.43432727456092834},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.43247368931770325},{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.41166165471076965},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.34892717003822327},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.31716471910476685},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0995820164680481},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019992","descriptor_name":"Databases as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019992","descriptor_name":"Databases as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019992","descriptor_name":"Databases as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-020-03898-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-020-03898-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03898-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:33297947","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33297947","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:76689315421d46529d58211c0d1b444b","is_oa":true,"landing_page_url":"https://doaj.org/article/76689315421d46529d58211c0d1b444b","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 21, Iss 1, Pp 1-17 (2020)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7724880","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7724880","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-020-03898-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-020-03898-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03898-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4399999976158142,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3112330887.pdf","grobid_xml":"https://content.openalex.org/works/W3112330887.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1486317198","https://openalex.org/W1690919088","https://openalex.org/W1975147762","https://openalex.org/W1994389483","https://openalex.org/W2031954078","https://openalex.org/W2043314049","https://openalex.org/W2044424923","https://openalex.org/W2062941476","https://openalex.org/W2088632292","https://openalex.org/W2113072832","https://openalex.org/W2119412782","https://openalex.org/W2137052779","https://openalex.org/W2148797284","https://openalex.org/W2154654747","https://openalex.org/W2183717576","https://openalex.org/W2259538443","https://openalex.org/W2346950316","https://openalex.org/W2444690946","https://openalex.org/W2605246672","https://openalex.org/W2605350416","https://openalex.org/W2775185492","https://openalex.org/W2790385355","https://openalex.org/W2793951981","https://openalex.org/W2798972759","https://openalex.org/W2800595743","https://openalex.org/W2896002881","https://openalex.org/W2950777612","https://openalex.org/W2960557205","https://openalex.org/W2968848985","https://openalex.org/W3037430960","https://openalex.org/W3037489518","https://openalex.org/W3097991661","https://openalex.org/W6630820455"],"related_works":["https://openalex.org/W3175975129","https://openalex.org/W4291511859","https://openalex.org/W4387302591","https://openalex.org/W4319455836","https://openalex.org/W2558461040","https://openalex.org/W2474546929","https://openalex.org/W4206326513","https://openalex.org/W3004450058","https://openalex.org/W2809645723","https://openalex.org/W3209981042"],"abstract_inverted_index":{"Through":[0],"the":[1,12,21],"performance":[2],"on":[3],"two":[4],"drug":[5],"repositioning":[6],"data":[7],"sets,":[8],"we":[9],"believe":[10],"that":[11],"HAMN":[13],"model":[14],"proposes":[15],"a":[16,31],"new":[17,32,36],"solution":[18],"to":[19,34],"improve":[20],"prediction":[22],"accuracy":[23],"of":[24],"drug-disease":[25],"associations":[26],"and":[27],"give":[28],"pharmaceutical":[29],"personnel":[30],"perspective":[33],"develop":[35],"drugs.":[37]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}