{"id":"https://openalex.org/W3084987735","doi":"https://doi.org/10.1186/s12859-020-03647-7","title":"A preliminary PET radiomics study of brain metastases using a fully automatic segmentation method","display_name":"A preliminary PET radiomics study of brain metastases using a fully automatic segmentation method","publication_year":2020,"publication_date":"2020-09-01","ids":{"openalex":"https://openalex.org/W3084987735","doi":"https://doi.org/10.1186/s12859-020-03647-7","mag":"3084987735","pmid":"https://pubmed.ncbi.nlm.nih.gov/32938360"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-020-03647-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-020-03647-7","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03647-7","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03647-7","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023090551","display_name":"Alessandro Stefano","orcid":"https://orcid.org/0000-0002-7189-1731"},"institutions":[{"id":"https://openalex.org/I4210095629","display_name":"Institute of Molecular Bioimaging and Physiology","ror":"https://ror.org/00s2j5046","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210095629","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandro Stefano","raw_affiliation_strings":["Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy","institution_ids":["https://openalex.org/I4210095629","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006558800","display_name":"Albert Comelli","orcid":"https://orcid.org/0000-0002-9290-6103"},"institutions":[{"id":"https://openalex.org/I4210095629","display_name":"Institute of Molecular Bioimaging and Physiology","ror":"https://ror.org/00s2j5046","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210095629","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210150906","display_name":"Ri.MED","ror":"https://ror.org/05qetrn02","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210150906"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Albert Comelli","raw_affiliation_strings":["Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy","Ri.MED Foundation, Palermo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy","institution_ids":["https://openalex.org/I4210095629","https://openalex.org/I4210155236"]},{"raw_affiliation_string":"Ri.MED Foundation, Palermo, Italy","institution_ids":["https://openalex.org/I4210150906"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027255502","display_name":"Valentina Bravat\u00e0","orcid":"https://orcid.org/0000-0001-9778-9252"},"institutions":[{"id":"https://openalex.org/I4210095629","display_name":"Institute of Molecular Bioimaging and Physiology","ror":"https://ror.org/00s2j5046","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210095629","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Valentina Bravat\u00e0","raw_affiliation_strings":["Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy. valentina.bravata@ibfm.cnr.it","Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy"],"raw_orcid":"https://orcid.org/0000-0001-9778-9252","affiliations":[{"raw_affiliation_string":"Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy. valentina.bravata@ibfm.cnr.it","institution_ids":["https://openalex.org/I4210095629"]},{"raw_affiliation_string":"Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy","institution_ids":["https://openalex.org/I4210095629","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002666922","display_name":"Stefano Barone","orcid":"https://orcid.org/0000-0002-0339-8435"},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefano Barone","raw_affiliation_strings":["University of Palermo, Palermo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Palermo, Palermo, Italy","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054705320","display_name":"Igor Daskalovski","orcid":null},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Igor Daskalovski","raw_affiliation_strings":["Department of Physics and Astronomy, University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics and Astronomy, University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080379940","display_name":"Gaetano Savoca","orcid":"https://orcid.org/0000-0002-6099-3476"},"institutions":[{"id":"https://openalex.org/I4210095629","display_name":"Institute of Molecular Bioimaging and Physiology","ror":"https://ror.org/00s2j5046","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210095629","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gaetano Savoca","raw_affiliation_strings":["Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy","institution_ids":["https://openalex.org/I4210095629","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085371815","display_name":"M.G. Sabini","orcid":"https://orcid.org/0000-0001-7865-8564"},"institutions":[{"id":"https://openalex.org/I4210135973","display_name":"Ospedale Cannizzaro","ror":"https://ror.org/03mtnpp42","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210135973"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Gabriella Sabini","raw_affiliation_strings":["Medical Physics Unit, Cannizzaro Hospital, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Physics Unit, Cannizzaro Hospital, Catania, Italy","institution_ids":["https://openalex.org/I4210135973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045741618","display_name":"Massimo Ippolito","orcid":null},"institutions":[{"id":"https://openalex.org/I4210135973","display_name":"Ospedale Cannizzaro","ror":"https://ror.org/03mtnpp42","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210135973"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimo Ippolito","raw_affiliation_strings":["Nuclear Medicine Department, Cannizzaro Hospital, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nuclear Medicine Department, Cannizzaro Hospital, Catania, Italy","institution_ids":["https://openalex.org/I4210135973"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011638733","display_name":"G. Russo","orcid":"https://orcid.org/0000-0003-1493-1087"},"institutions":[{"id":"https://openalex.org/I4210095629","display_name":"Institute of Molecular Bioimaging and Physiology","ror":"https://ror.org/00s2j5046","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210095629","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210135973","display_name":"Ospedale Cannizzaro","ror":"https://ror.org/03mtnpp42","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210135973"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giorgio Russo","raw_affiliation_strings":["Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy","Medical Physics Unit, Cannizzaro Hospital, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefal\u00f9, Italy","institution_ids":["https://openalex.org/I4210095629","https://openalex.org/I4210155236"]},{"raw_affiliation_string":"Medical Physics Unit, Cannizzaro Hospital, Catania, Italy","institution_ids":["https://openalex.org/I4210135973"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5027255502"],"corresponding_institution_ids":["https://openalex.org/I4210095629","https://openalex.org/I4210155236"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":5.6297,"has_fulltext":true,"cited_by_count":59,"citation_normalized_percentile":{"value":0.97064052,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"21","issue":"S8","first_page":"325","last_page":"325"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.7239000201225281,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.7239000201225281,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11600","display_name":"Brain Metastases and Treatment","score":0.15719999372959137,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.04769999906420708,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiomics","display_name":"Radiomics","score":0.6362497806549072},{"id":"https://openalex.org/keywords/positron-emission-tomography","display_name":"Positron emission tomography","score":0.5501046776771545},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5438509583473206},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5388251543045044},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.5305590629577637},{"id":"https://openalex.org/keywords/linear-discriminant-analysis","display_name":"Linear discriminant analysis","score":0.5300709009170532},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5077475309371948},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4722401797771454},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.45203864574432373},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4196426272392273},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.37864330410957336},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.32192906737327576}],"concepts":[{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.6362497806549072},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.5501046776771545},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5438509583473206},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5388251543045044},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.5305590629577637},{"id":"https://openalex.org/C69738355","wikidata":"https://www.wikidata.org/wiki/Q1228929","display_name":"Linear discriminant analysis","level":2,"score":0.5300709009170532},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5077475309371948},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4722401797771454},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.45203864574432373},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4196426272392273},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.37864330410957336},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.32192906737327576},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12859-020-03647-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-020-03647-7","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03647-7","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:32938360","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32938360","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:3c0c25b5466040a4ad51374a75d9eb8d","is_oa":true,"landing_page_url":"https://doaj.org/article/3c0c25b5466040a4ad51374a75d9eb8d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 21, Iss S8, Pp 1-14 (2020)","raw_type":"article"},{"id":"pmh:oai:iris.unipa.it:10447/556785","is_oa":true,"landing_page_url":"http://hdl.handle.net/10447/556785","pdf_url":null,"source":{"id":"https://openalex.org/S4306401065","display_name":"Nova Science Publishers (Nova Science Publishers, Inc.)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7493376","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7493376","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-020-03647-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-020-03647-7","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03647-7","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6100000143051147,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320324632","display_name":"Ministero dello Sviluppo Economico","ror":"https://ror.org/011z3ff80"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3084987735.pdf","grobid_xml":"https://content.openalex.org/works/W3084987735.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W1499943936","https://openalex.org/W1538419182","https://openalex.org/W1567381270","https://openalex.org/W1967362871","https://openalex.org/W1972111840","https://openalex.org/W1973499928","https://openalex.org/W1988445395","https://openalex.org/W1993804990","https://openalex.org/W1995969389","https://openalex.org/W2010632044","https://openalex.org/W2027201113","https://openalex.org/W2033069725","https://openalex.org/W2038751110","https://openalex.org/W2044465660","https://openalex.org/W2047028172","https://openalex.org/W2076649680","https://openalex.org/W2079330163","https://openalex.org/W2095272243","https://openalex.org/W2098417097","https://openalex.org/W2099775285","https://openalex.org/W2113122028","https://openalex.org/W2116465095","https://openalex.org/W2125792957","https://openalex.org/W2131207601","https://openalex.org/W2155263737","https://openalex.org/W2174661749","https://openalex.org/W2231512867","https://openalex.org/W2406251305","https://openalex.org/W2530141817","https://openalex.org/W2546544979","https://openalex.org/W2554272155","https://openalex.org/W2626467069","https://openalex.org/W2725801426","https://openalex.org/W2765594621","https://openalex.org/W2773727367","https://openalex.org/W2790196831","https://openalex.org/W2791478600","https://openalex.org/W2888082487","https://openalex.org/W2891226040","https://openalex.org/W2908672892","https://openalex.org/W2909240409","https://openalex.org/W2919159054","https://openalex.org/W2920589322","https://openalex.org/W2921026029","https://openalex.org/W2953428836","https://openalex.org/W2964868046","https://openalex.org/W2966145532","https://openalex.org/W2970761576","https://openalex.org/W2982334763","https://openalex.org/W2991460632","https://openalex.org/W3000991698","https://openalex.org/W3001577747","https://openalex.org/W3011894004","https://openalex.org/W4238731984","https://openalex.org/W4243398340","https://openalex.org/W4285717592"],"related_works":["https://openalex.org/W3000891326","https://openalex.org/W2496284264","https://openalex.org/W4205100762","https://openalex.org/W2734724112","https://openalex.org/W2582997534","https://openalex.org/W3009210156","https://openalex.org/W4388577230","https://openalex.org/W4385221818","https://openalex.org/W3030796519","https://openalex.org/W4225316186"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Positron":[2],"Emission":[3],"Tomography":[4],"(PET)":[5],"is":[6,23,54,295],"increasingly":[7],"utilized":[8],"in":[9,20,30,76,154,210,274,320],"radiomics":[10,97,152],"studies":[11,135],"for":[12,115,121,166,179,238,302],"treatment":[13,106,344,355],"evaluation":[14,123],"purposes.":[15],"Nevertheless,":[16],"lesion":[17,306],"volume":[18,52],"identification":[19],"PET":[21,46,134,315],"images":[22],"a":[24,61,86,177,311],"critical":[25],"and":[26,41,64,90,118,136,169,192,200,206,227,265,282,307,318,325,346],"still":[27],"challenging":[28],"step":[29],"the":[31,37,49,129,148,216,219,232,286,321,351],"process":[32],"of":[33,45,151,218,234,288,313,323,353],"radiomics,":[34],"due":[35],"to":[36,70,91,95,99,105,142,146,196,231,298,309,342],"low":[38],"spatial":[39],"resolution":[40],"high":[42],"noise":[43],"level":[44],"images.":[47],"Currently,":[48],"biological":[50],"target":[51],"(BTV)":[53],"manually":[55],"contoured":[56],"by":[57],"nuclear":[58],"physicians,":[59],"with":[60,156,271,328,331],"time":[62],"expensive":[63],"operator-dependent":[65],"procedure.":[66],"This":[67],"study":[68],"aims":[69],"obtain":[71],"BTVs":[72,94],"from":[73],"cerebral":[74],"metastases":[75],"patients":[77,102,155],"who":[78,103],"underwent":[79],"L-[":[80],"11":[81],"C]methionine":[82],"(11C-MET)":[83],"PET,":[84],"using":[85,128,215],"fully":[87],"automatic":[88],"procedure":[89],"use":[92,233,287],"these":[93,110],"extract":[96,143,299],"features":[98,145,187,222,242,301,316],"stratify":[100],"between":[101,198],"respond":[104],"or":[107],"not.":[108],"For":[109,183],"purposes,":[111],"31":[112],"brain":[113,157],"metastases,":[114],"predictive":[116,184,324],"evaluation,":[117,185,240,348],"25":[119],"ones,":[120],"follow-up":[122,239,326],"after":[124,203],"treatment,":[125],"were":[126,140,194,269],"delineated":[127],"proposed":[130,293],"method.":[131],"Successively,":[132],"11C-MET":[133,314],"related":[137],"volumetric":[138],"segmentations":[139],"used":[141,175],"108":[144,300],"investigate":[147],"potential":[149],"application":[150],"analysis":[153,173,276],"metastases.":[158],"A":[159],"novel":[160],"statistical":[161],"system":[162,294],"has":[163],"been":[164],"implemented":[165],"feature":[167,180,204],"reduction":[168,205],"selection,":[170],"while":[171],"discriminant":[172,275],"was":[174,213],"as":[176],"method":[178],"classification.":[181],"Results":[182],"3":[186],"(asphericity,":[188],"low-intensity":[189],"run":[190],"emphasis,":[191],"complexity)":[193],"able":[195,296],"discriminate":[197],"responder":[199],"non-responder":[201],"patients,":[202],"selection.":[207],"Best":[208],"performance":[209,273],"patient":[211,332],"discrimination":[212],"obtained":[214],"combination":[217],"three":[220],"selected":[221,270],"(sensitivity":[223,278],"81.23%,":[224],"specificity":[225,280],"73.97%,":[226],"accuracy":[228,283],"78.27%)":[229],"compared":[230],"all":[235,289],"features.":[236,290],"Secondly,":[237],"8":[241,319],"(SUV":[243],"mean":[244,256,259],",":[245,248,251],"SUL":[246,252,262],"peak":[247,253,263],"SUV":[249,255,260],"min":[250],"prod-surface-area,":[254],"prod-sphericity,":[257,264],"surface":[258],"3,":[261],"second":[266],"angular":[267],"moment)":[268],"optimal":[272],"classification":[277],"86.28%,":[279],"87.75%,":[281],"86.57%)":[284],"outperforming":[285],"Conclusions":[291],"The":[292],"i)":[297],"each":[303],"automatically":[304],"segmented":[305],"ii)":[308],"select":[310],"sub-panel":[312],"(3":[317],"case":[322],"evaluation),":[327],"valuable":[329],"association":[330],"outcome.":[333],"We":[334],"believe":[335],"that":[336],"our":[337],"model":[338],"can":[339],"be":[340],"useful":[341],"improve":[343],"response":[345],"prognosis":[347],"potentially":[349],"allowing":[350],"personalization":[352],"cancer":[354],"plans.":[356]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":6}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2025-10-10T00:00:00"}