{"id":"https://openalex.org/W2996771978","doi":"https://doi.org/10.1186/s12859-019-3306-3","title":"SpliceFinder: ab initio prediction of splice sites using convolutional neural network","display_name":"SpliceFinder: ab initio prediction of splice sites using convolutional neural network","publication_year":2019,"publication_date":"2019-12-01","ids":{"openalex":"https://openalex.org/W2996771978","doi":"https://doi.org/10.1186/s12859-019-3306-3","mag":"2996771978","pmid":"https://pubmed.ncbi.nlm.nih.gov/31881982"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-019-3306-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-3306-3","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-019-3306-3","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-019-3306-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029082731","display_name":"Ruohan Wang","orcid":"https://orcid.org/0000-0003-2327-2888"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Ruohan Wang","raw_affiliation_strings":["Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078321845","display_name":"Zishuai Wang","orcid":"https://orcid.org/0000-0002-4496-8430"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Zishuai Wang","raw_affiliation_strings":["Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100356291","display_name":"Jianping Wang","orcid":"https://orcid.org/0000-0002-9318-1482"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":true,"raw_author_name":"Jianping Wang","raw_affiliation_strings":["Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China. jianwang@cityu.edu.hk","Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China. jianwang@cityu.edu.hk","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083428910","display_name":"Shuai Cheng Li","orcid":"https://orcid.org/0000-0001-6246-6349"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":true,"raw_author_name":"Shuaicheng Li","raw_affiliation_strings":["Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China. shuaicli@cityu.edu.hk","Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China. shuaicli@cityu.edu.hk","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Department of Computer Science, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong, China","institution_ids":["https://openalex.org/I168719708"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5083428910","https://openalex.org/A5100356291"],"corresponding_institution_ids":["https://openalex.org/I168719708"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":2.4276,"has_fulltext":true,"cited_by_count":76,"citation_normalized_percentile":{"value":0.90279511,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"20","issue":"S23","first_page":"652","last_page":"652"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9812999963760376,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9812999963760376,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.7528725266456604},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5662923455238342},{"id":"https://openalex.org/keywords/splice","display_name":"splice","score":0.5550546646118164},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5545432567596436},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.5196508169174194},{"id":"https://openalex.org/keywords/ab-initio","display_name":"Ab initio","score":0.511578381061554},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4830923080444336},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.220199316740036},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.21616002917289734},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16873988509178162},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.10363802313804626},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.06277155876159668}],"concepts":[{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.7528725266456604},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5662923455238342},{"id":"https://openalex.org/C2780989783","wikidata":"https://www.wikidata.org/wiki/Q7578557","display_name":"splice","level":3,"score":0.5550546646118164},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5545432567596436},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.5196508169174194},{"id":"https://openalex.org/C2781442258","wikidata":"https://www.wikidata.org/wiki/Q46310","display_name":"Ab initio","level":2,"score":0.511578381061554},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4830923080444336},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.220199316740036},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.21616002917289734},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16873988509178162},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10363802313804626},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.06277155876159668},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012326","descriptor_name":"RNA Splicing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012326","descriptor_name":"RNA Splicing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012326","descriptor_name":"RNA Splicing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D022821","descriptor_name":"RNA Splice Sites","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D022821","descriptor_name":"RNA Splice Sites","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D022821","descriptor_name":"RNA Splice Sites","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12859-019-3306-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-3306-3","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-019-3306-3","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31881982","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31881982","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:bc9b544135f54e3380e9c243cede5526","is_oa":false,"landing_page_url":"https://doaj.org/article/bc9b544135f54e3380e9c243cede5526","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 20, Iss S23, Pp 1-13 (2019)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6933889","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6933889","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:publications/986865cc-e57b-4ee9-b2c0-ba2fa04ca999","is_oa":true,"landing_page_url":"https://hdl.handle.net/2031/986865cc-e57b-4ee9-b2c0-ba2fa04ca999","pdf_url":null,"source":{"id":"https://openalex.org/S7407055387","display_name":"CityU Scholars","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Wang, R, Wang, Z, Wang, J & Li, S 2019, 'SpliceFinder : ab initio prediction of splice sites using convolutional neural network', BMC Bioinformatics, vol. 20, no. Supp. 23, 652. https://doi.org/10.1186/s12859-019-3306-3","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1186/s12859-019-3306-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-3306-3","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-019-3306-3","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15","score":0.5699999928474426}],"awards":[{"id":"https://openalex.org/G7946582735","display_name":null,"funder_award_id":"11257316","funder_id":"https://openalex.org/F4320309893","funder_display_name":"City University of Hong Kong"}],"funders":[{"id":"https://openalex.org/F4320309893","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2996771978.pdf","grobid_xml":"https://content.openalex.org/works/W2996771978.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W217289105","https://openalex.org/W1583837637","https://openalex.org/W1594031697","https://openalex.org/W1663973292","https://openalex.org/W1785973136","https://openalex.org/W1841068694","https://openalex.org/W1965051773","https://openalex.org/W1965760291","https://openalex.org/W1977728729","https://openalex.org/W1983518953","https://openalex.org/W1990210083","https://openalex.org/W2009086942","https://openalex.org/W2009618608","https://openalex.org/W2024057982","https://openalex.org/W2041905891","https://openalex.org/W2056967728","https://openalex.org/W2063861171","https://openalex.org/W2064675550","https://openalex.org/W2095705004","https://openalex.org/W2097065948","https://openalex.org/W2100495367","https://openalex.org/W2102109071","https://openalex.org/W2106356212","https://openalex.org/W2110400205","https://openalex.org/W2119821739","https://openalex.org/W2122789575","https://openalex.org/W2126144698","https://openalex.org/W2131581981","https://openalex.org/W2146760000","https://openalex.org/W2151949149","https://openalex.org/W2155684118","https://openalex.org/W2156387975","https://openalex.org/W2158266834","https://openalex.org/W2163570826","https://openalex.org/W2163605009","https://openalex.org/W2498119267","https://openalex.org/W2604272474","https://openalex.org/W2605409611","https://openalex.org/W2809442901","https://openalex.org/W2908351833","https://openalex.org/W2909194804","https://openalex.org/W2911964244","https://openalex.org/W3107817112","https://openalex.org/W4230105992","https://openalex.org/W4245310067","https://openalex.org/W4246084279","https://openalex.org/W4247292500","https://openalex.org/W4297957988","https://openalex.org/W6601224256"],"related_works":["https://openalex.org/W2029220916","https://openalex.org/W2274928342","https://openalex.org/W1552032432","https://openalex.org/W1505791290","https://openalex.org/W3007430196","https://openalex.org/W2032059901","https://openalex.org/W2345230016","https://openalex.org/W2008389025","https://openalex.org/W2134451695","https://openalex.org/W2027970165"],"abstract_inverted_index":{"BACKGROUND:":[0],"Identifying":[1],"splice":[2,25,34,49,78,101,117,159,206,220,244,277,291],"sites":[3,35,79,102,207],"is":[4,138,171,295],"a":[5,90,213,273],"necessary":[6],"step":[7],"to":[8,56,89,115,130,140,154,297],"analyze":[9],"the":[10,41,46,53,65,68,76,121,142,146,152,165,175,202,242,252],"location":[11],"and":[12,19,27,71,150,195,261,287,305],"structure":[13],"of":[14,158,168,186,205,255],"genes.":[15],"Two":[16],"dinucleotides,":[17],"GT":[18],"AG,":[20],"are":[21,31,308],"highly":[22],"frequent":[23],"on":[24,33,74,110,208,251,268],"sites,":[26,50],"many":[28],"other":[29,181,218,298],"patterns":[30],"also":[32],"with":[36,67,212,217],"important":[37],"biological":[38],"functions.":[39],"Meanwhile,":[40],"dinucleotides":[42],"occur":[43],"frequently":[44],"at":[45,310],"sequences":[47,66,211,254],"without":[48,264,300],"which":[51,144,170,282],"makes":[52],"prediction":[54,222,279],"prone":[55],"generate":[57],"false":[58,93,231,285],"positives.":[59],"Most":[60],"existing":[61,176,182],"tools":[62],"select":[63],"all":[64],"two":[69],"dimers":[70],"then":[72],"focus":[73],"distinguishing":[75],"true":[77],"from":[80],"those":[81],"pseudo":[82],"ones.":[83],"Such":[84],"an":[85],"approach":[86,137],"will":[87,97],"lead":[88],"decrease":[91],"in":[92,99,184,227],"positives;":[94],"however,":[95],"it":[96],"result":[98],"non-canonical":[100,243,290],"missing.":[103],"RESULT:":[104],"We":[105],"have":[106,271],"designed":[107],"SpliceFinder":[108,199,224,240,248,294],"based":[109],"convolutional":[111],"neural":[112,133],"network":[113],"(CNN)":[114],"predict":[116],"sites.":[118,160,245,292],"To":[119],"achieve":[120],"ab":[122,275],"initio":[123,276],"prediction,":[124],"we":[125,270],"used":[126],"human":[127],"genomic":[128,210,253],"data":[129,147],"train":[131],"our":[132],"network.":[134],"An":[135],"iterative":[136],"adopted":[139],"reconstruct":[141],"dataset,":[143],"tackles":[145],"unbalance":[148],"problem":[149],"forces":[151],"model":[153],"learn":[155],"more":[156],"features":[157],"The":[161,178,302],"proposed":[162,272],"CNN":[163],"obtains":[164],"classification":[166],"accuracy":[167],"90.25%,":[169],"10%":[172],"higher":[173,236],"than":[174,237],"algorithms.":[177],"method":[179],"outperforms":[180],"methods":[183],"terms":[185],"area":[187],"under":[188],"receiver":[189],"operating":[190],"characteristics":[191],"(AUC),":[192],"recall,":[193],"precision,":[194],"F1":[196],"score.":[197],"Furthermore,":[198],"can":[200,288],"find":[201],"exact":[203],"position":[204],"long":[209],"sliding":[214],"window.":[215],"Compared":[216],"state-of-the-art":[219],"site":[221,278],"tools,":[223],"generates":[225,283],"results":[226],"about":[228],"half":[229],"lower":[230],"positive":[232],"while":[233],"keeping":[234],"recall":[235],"0.8.":[238],"Also,":[239],"captures":[241],"In":[246],"addition,":[247],"performs":[249],"well":[250],"Drosophila":[256],"melanogaster,":[257],"Mus":[258],"musculus,":[259],"Rattus,":[260],"Danio":[262],"rerio":[263],"retraining.":[265,301],"CONCLUSION:":[266],"Based":[267],"CNN,":[269],"new":[274],"tool,":[280],"SpliceFinder,":[281],"less":[284],"positives":[286],"detect":[289],"Additionally,":[293],"transferable":[296],"species":[299],"source":[303],"code":[304],"additional":[306],"materials":[307],"available":[309],"https://gitlab.deepomics.org/wangruohan/SpliceFinder.":[311]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":17},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":9}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}