{"id":"https://openalex.org/W2996092916","doi":"https://doi.org/10.1186/s12859-019-3001-4","title":"Selection of microbial biomarkers with genetic algorithm and principal component analysis","display_name":"Selection of microbial biomarkers with genetic algorithm and principal component analysis","publication_year":2019,"publication_date":"2019-12-01","ids":{"openalex":"https://openalex.org/W2996092916","doi":"https://doi.org/10.1186/s12859-019-3001-4","mag":"2996092916","pmid":"https://pubmed.ncbi.nlm.nih.gov/31823717"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-019-3001-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-3001-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-3001-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-3001-4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059001271","display_name":"Ping Zhang","orcid":"https://orcid.org/0000-0002-3907-1127"},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Ping Zhang","raw_affiliation_strings":["Menzies Health Institute QLD, Griffith University, Gold Coast, Australia. p.zhang@griffith.edu.au","Menzies Health Institute QLD, Griffith University, Gold Coast, Australia"],"raw_orcid":"https://orcid.org/0000-0002-3907-1127","affiliations":[{"raw_affiliation_string":"Menzies Health Institute QLD, Griffith University, Gold Coast, Australia. p.zhang@griffith.edu.au","institution_ids":["https://openalex.org/I11701301"]},{"raw_affiliation_string":"Menzies Health Institute QLD, Griffith University, Gold Coast, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031114729","display_name":"Nicholas P. West","orcid":"https://orcid.org/0000-0002-5482-4182"},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Nicholas P. West","raw_affiliation_strings":["Menzies Health Institute QLD, Griffith University, Gold Coast, Australia","School of Medical Science, Griffith University, Gold Coast, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Menzies Health Institute QLD, Griffith University, Gold Coast, Australia","institution_ids":["https://openalex.org/I11701301"]},{"raw_affiliation_string":"School of Medical Science, Griffith University, Gold Coast, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073053158","display_name":"Pin-Yen Chen","orcid":"https://orcid.org/0000-0002-2187-6939"},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Pin-Yen Chen","raw_affiliation_strings":["Menzies Health Institute QLD, Griffith University, Gold Coast, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Menzies Health Institute QLD, Griffith University, Gold Coast, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067604502","display_name":"Mike W. C. Thang","orcid":"https://orcid.org/0000-0002-1480-3563"},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Mike W. C. Thang","raw_affiliation_strings":["QFAB Bioinformatics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"QFAB Bioinformatics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007948957","display_name":"Gareth Price","orcid":"https://orcid.org/0000-0003-2439-8650"},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Gareth Price","raw_affiliation_strings":["QFAB Bioinformatics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"QFAB Bioinformatics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091562975","display_name":"Allan W. Cripps","orcid":"https://orcid.org/0000-0002-8755-932X"},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Allan W. Cripps","raw_affiliation_strings":["Menzies Health Institute QLD, Griffith University, Gold Coast, Australia","School of Medicine, Griffith University, Gold Coast, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Menzies Health Institute QLD, Griffith University, Gold Coast, Australia","institution_ids":["https://openalex.org/I11701301"]},{"raw_affiliation_string":"School of Medicine, Griffith University, Gold Coast, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080289942","display_name":"Amanda J. Cox","orcid":"https://orcid.org/0000-0003-3684-0952"},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Amanda J. Cox","raw_affiliation_strings":["School of Medical Science, Griffith University, Gold Coast, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medical Science, Griffith University, Gold Coast, Australia","institution_ids":["https://openalex.org/I11701301"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5059001271"],"corresponding_institution_ids":["https://openalex.org/I11701301"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":4.0979,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.94540834,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"20","issue":"S6","first_page":"413","last_page":"413"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.0843999981880188,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.0843999981880188,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.08190000057220459,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13141","display_name":"Statistical Methods and Applications","score":0.05950000137090683,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/principal-component-analysis","display_name":"Principal component analysis","score":0.8523533344268799},{"id":"https://openalex.org/keywords/predictive-modelling","display_name":"Predictive modelling","score":0.549968957901001},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5465261340141296},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.5449409484863281},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4498412609100342},{"id":"https://openalex.org/keywords/variance","display_name":"Variance (accounting)","score":0.4400617480278015},{"id":"https://openalex.org/keywords/explained-variation","display_name":"Explained variation","score":0.41648024320602417},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.37526369094848633},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.329448401927948}],"concepts":[{"id":"https://openalex.org/C27438332","wikidata":"https://www.wikidata.org/wiki/Q2873","display_name":"Principal component analysis","level":2,"score":0.8523533344268799},{"id":"https://openalex.org/C45804977","wikidata":"https://www.wikidata.org/wiki/Q7239673","display_name":"Predictive modelling","level":2,"score":0.549968957901001},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5465261340141296},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.5449409484863281},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4498412609100342},{"id":"https://openalex.org/C196083921","wikidata":"https://www.wikidata.org/wiki/Q7915758","display_name":"Variance (accounting)","level":2,"score":0.4400617480278015},{"id":"https://openalex.org/C138528620","wikidata":"https://www.wikidata.org/wiki/Q2510752","display_name":"Explained variation","level":2,"score":0.41648024320602417},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.37526369094848633},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.329448401927948},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C121955636","wikidata":"https://www.wikidata.org/wiki/Q4116214","display_name":"Accounting","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/s12859-019-3001-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-3001-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-3001-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31823717","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31823717","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:research-repository.griffith.edu.au:10072/389850","is_oa":true,"landing_page_url":"http://hdl.handle.net/10072/389850","pdf_url":"http://hdl.handle.net/10072/389850","source":{"id":"https://openalex.org/S4306402548","display_name":"Griffith Research Online (Griffith University, Queensland, Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I11701301","host_organization_name":"Griffith University","host_organization_lineage":["https://openalex.org/I11701301"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6904994","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6904994","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:a2cbea6643b4448fbee6832a521db741","is_oa":true,"landing_page_url":"https://doaj.org/article/a2cbea6643b4448fbee6832a521db741","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 20, Iss S6, Pp 1-8 (2019)","raw_type":"article"},{"id":"pmh:oai:espace.library.uq.edu.au:UQ:b3e9a38","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306402388","display_name":"Queensland's institutional digital repository (The University of Queensland)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I165143802","host_organization_name":"The University of Queensland","host_organization_lineage":["https://openalex.org/I165143802"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1186/s12859-019-3001-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-3001-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-3001-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320981","display_name":"Griffith University","ror":"https://ror.org/02sc3r913"},{"id":"https://openalex.org/F4320332761","display_name":"Australian Institute of Sport","ror":"https://ror.org/01e4w2966"},{"id":"https://openalex.org/F4320334861","display_name":"Griffith Health Institute, Griffith University","ror":"https://ror.org/02sc3r913"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2996092916.pdf","grobid_xml":"https://content.openalex.org/works/W2996092916.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1482365120","https://openalex.org/W1811186957","https://openalex.org/W1849733024","https://openalex.org/W1988925586","https://openalex.org/W2033829415","https://openalex.org/W2035659356","https://openalex.org/W2062550323","https://openalex.org/W2072970694","https://openalex.org/W2094250612","https://openalex.org/W2103441770","https://openalex.org/W2108718991","https://openalex.org/W2113925621","https://openalex.org/W2115589652","https://openalex.org/W2128711701","https://openalex.org/W2128769815","https://openalex.org/W2147163488","https://openalex.org/W2174278940","https://openalex.org/W2219829573","https://openalex.org/W2401404581","https://openalex.org/W2409427249","https://openalex.org/W2497884722","https://openalex.org/W2508175702","https://openalex.org/W2513506562","https://openalex.org/W2514672208","https://openalex.org/W2537634445","https://openalex.org/W2582743722","https://openalex.org/W2599897974","https://openalex.org/W2794286144","https://openalex.org/W2797413896","https://openalex.org/W2803457956","https://openalex.org/W2809642430","https://openalex.org/W2810208030","https://openalex.org/W2914090235","https://openalex.org/W2950746887"],"related_works":["https://openalex.org/W2083862258","https://openalex.org/W41212085","https://openalex.org/W2026442532","https://openalex.org/W2062283790","https://openalex.org/W2111729958","https://openalex.org/W2397808047","https://openalex.org/W2116434085","https://openalex.org/W2945254547","https://openalex.org/W2036969276","https://openalex.org/W2061057072"],"abstract_inverted_index":{"BACKGROUND:":[0],"Principal":[1],"components":[2,38,67,137],"analysis":[3],"(PCA)":[4],"is":[5,24],"often":[6],"used":[7,42],"to":[8,43,93,101,144,161,194],"find":[9],"characteristic":[10],"patterns":[11],"associated":[12,120],"with":[13,121,164,173,218,239],"certain":[14],"diseases":[15],"by":[16,140,213],"reducing":[17],"variable":[18],"numbers":[19],"before":[20],"a":[21,63,95,103,110,191],"predictive":[22],"model":[23,105],"built,":[25],"particularly":[26],"when":[27],"some":[28],"variables":[29,92,205],"are":[30,41,237],"correlated.":[31],"Usually,":[32],"the":[33,88,133,145,149,154,158,182,201,208],"first":[34],"two":[35,51],"or":[36],"three":[37],"from":[39,75],"PCA":[40,108,172,185],"determine":[44],"whether":[45],"individuals":[46,74],"can":[47,81,215,226],"be":[48,82,216,227],"clustered":[49],"into":[50],"classification":[52],"groups":[53],"based":[54],"on":[55],"pre-determined":[56],"criteria:":[57],"control":[58],"and":[59,84,109,123,160],"disease":[60],"group.":[61],"However,":[62],"combination":[64,90,134],"of":[65,91,117,135,170,184],"other":[66],"may":[68,199],"exist":[69],"which":[70],"better":[71],"distinguish":[72],"diseased":[73],"healthy":[76],"controls.":[77],"Genetic":[78],"algorithms":[79],"(GAs)":[80],"useful":[83,228],"efficient":[85],"for":[86,114,186,220,229],"searching":[87],"best":[89],"build":[94,195],"prediction":[96,104,129,196,202],"model.":[97],"This":[98],"study":[99],"aimed":[100],"develop":[102],"that":[106,152,198,210],"combines":[107],"genetic":[111],"algorithm":[112,180,225],"(GA)":[113],"identifying":[115],"sets":[116],"bacterial":[118],"species":[119],"obesity":[122],"metabolic":[124],"syndrome":[125],"(Mets).":[126],"RESULTS:":[127],"The":[128,168,178,204,224],"models":[130,146,162,197],"built":[131,147,163],"using":[132,148],"principal":[136],"(PCs)":[138],"selected":[139,165,212],"GA":[141,174,214],"were":[142,175,211],"compared":[143],"top":[150],"PCs":[151,209],"explained":[153],"most":[155],"variance":[156],"in":[157,207],"sample":[159],"original":[166],"variables.":[167,242],"advantages":[169],"combining":[171],"demonstrated.":[176],"CONCLUSIONS:":[177],"proposed":[179],"overcomes":[181],"limitation":[183],"data":[187,236],"analysis.":[188],"It":[189],"offers":[190],"new":[192],"way":[193],"improve":[200],"accuracy.":[203],"included":[206],"combined":[217],"flexibility":[219],"potential":[221],"clinical":[222],"applications.":[223],"many":[230],"biological":[231],"studies":[232],"where":[233],"high":[234],"dimensional":[235],"collected":[238],"highly":[240],"correlated":[241]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1}],"updated_date":"2026-08-11T07:18:39.950985","created_date":"2025-10-10T00:00:00"}