{"id":"https://openalex.org/W2946834045","doi":"https://doi.org/10.1186/s12859-019-2840-3","title":"m6Acomet: large-scale functional prediction of individual m6A RNA methylation sites from an RNA co-methylation network","display_name":"m6Acomet: large-scale functional prediction of individual m6A RNA methylation sites from an RNA co-methylation network","publication_year":2019,"publication_date":"2019-05-02","ids":{"openalex":"https://openalex.org/W2946834045","doi":"https://doi.org/10.1186/s12859-019-2840-3","mag":"2946834045","pmid":"https://pubmed.ncbi.nlm.nih.gov/31046660"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-019-2840-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-2840-3","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-2840-3","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-2840-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053933966","display_name":"Xiangyu Wu","orcid":"https://orcid.org/0000-0002-4562-9721"},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]},{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN","GB"],"is_corresponding":false,"raw_author_name":"Xiangyu Wu","raw_affiliation_strings":["Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China","Institute of Ageing & Chronic Disease, University of Liverpool, L7 8TX, Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"Institute of Ageing & Chronic Disease, University of Liverpool, L7 8TX, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103098229","display_name":"Zhen Wei","orcid":"https://orcid.org/0000-0002-5148-7651"},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]},{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["CN","GB"],"is_corresponding":false,"raw_author_name":"Zhen Wei","raw_affiliation_strings":["Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China","Institute of Ageing & Chronic Disease, University of Liverpool, L7 8TX, Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"Institute of Ageing & Chronic Disease, University of Liverpool, L7 8TX, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090892714","display_name":"Kunqi Chen","orcid":"https://orcid.org/0000-0002-6025-8957"},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]},{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN","GB"],"is_corresponding":false,"raw_author_name":"Kunqi Chen","raw_affiliation_strings":["Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China","Institute of Ageing & Chronic Disease, University of Liverpool, L7 8TX, Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"Institute of Ageing & Chronic Disease, University of Liverpool, L7 8TX, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100358790","display_name":"Qing Zhang","orcid":"https://orcid.org/0000-0002-1160-2715"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Qing Zhang","raw_affiliation_strings":["Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China","Present address: Harvard T.H. Chan School of Public Health, Harvard University, 655 Huntington Avenue, Boston, MA, 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"Present address: Harvard T.H. Chan School of Public Health, Harvard University, 655 Huntington Avenue, Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085156744","display_name":"Jionglong Su","orcid":"https://orcid.org/0000-0001-5360-6493"},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jionglong Su","raw_affiliation_strings":["Department of Mathematical Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China","institution_ids":["https://openalex.org/I69356397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113566766","display_name":"Hui Liu","orcid":"https://orcid.org/0000-0001-8845-4813"},"institutions":[{"id":"https://openalex.org/I25757504","display_name":"China University of Mining and Technology","ror":"https://ror.org/01xt2dr21","country_code":"CN","type":"education","lineage":["https://openalex.org/I25757504"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Liu","raw_affiliation_strings":["School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I25757504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100351875","display_name":"Lin Zhang","orcid":"https://orcid.org/0000-0002-7404-5231"},"institutions":[{"id":"https://openalex.org/I25757504","display_name":"China University of Mining and Technology","ror":"https://ror.org/01xt2dr21","country_code":"CN","type":"education","lineage":["https://openalex.org/I25757504"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lin Zhang","raw_affiliation_strings":["School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, Jiangsu, China. lin.zhang@cumt.edu.cn","School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, Jiangsu, China. lin.zhang@cumt.edu.cn","institution_ids":[]},{"raw_affiliation_string":"School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I25757504"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062986831","display_name":"Jia Meng","orcid":"https://orcid.org/0000-0003-3455-205X"},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Jia Meng","raw_affiliation_strings":["Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China. jia.meng@xjtlu.edu.cn","Institute of Integrative Biology, University of Liverpool, L7 8TX, Liverpool, UK. jia.meng@xjtlu.edu.cn","Institute of Integrative Biology, University of Liverpool, L7 8TX, Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China. jia.meng@xjtlu.edu.cn","institution_ids":[]},{"raw_affiliation_string":"Institute of Integrative Biology, University of Liverpool, L7 8TX, Liverpool, UK. jia.meng@xjtlu.edu.cn","institution_ids":[]},{"raw_affiliation_string":"Institute of Integrative Biology, University of Liverpool, L7 8TX, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5062986831"],"corresponding_institution_ids":["https://openalex.org/I146655781"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":2.5686,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.90524165,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"20","issue":"1","first_page":"223","last_page":"223"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.9955000281333923,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rna-methylation","display_name":"RNA methylation","score":0.7994493246078491},{"id":"https://openalex.org/keywords/n6-methyladenosine","display_name":"N6-Methyladenosine","score":0.7408177852630615},{"id":"https://openalex.org/keywords/methylation","display_name":"Methylation","score":0.7101106643676758},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.6988547444343567},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6496265530586243},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6266343593597412},{"id":"https://openalex.org/keywords/epigenetics","display_name":"Epigenetics","score":0.5175787210464478},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.4545454680919647},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.37834134697914124},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.306526243686676},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.27921563386917114},{"id":"https://openalex.org/keywords/methyltransferase","display_name":"Methyltransferase","score":0.24782758951187134}],"concepts":[{"id":"https://openalex.org/C2909856833","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"RNA methylation","level":5,"score":0.7994493246078491},{"id":"https://openalex.org/C2775963939","wikidata":"https://www.wikidata.org/wiki/Q6951996","display_name":"N6-Methyladenosine","level":5,"score":0.7408177852630615},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.7101106643676758},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6988547444343567},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6496265530586243},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6266343593597412},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.5175787210464478},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.4545454680919647},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.37834134697914124},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.306526243686676},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.27921563386917114},{"id":"https://openalex.org/C91965660","wikidata":"https://www.wikidata.org/wiki/Q415875","display_name":"Methyltransferase","level":4,"score":0.24782758951187134}],"mesh":[{"descriptor_ui":"D000241","descriptor_name":"Adenosine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D000241","descriptor_name":"Adenosine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D000241","descriptor_name":"Adenosine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D000241","descriptor_name":"Adenosine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000241","descriptor_name":"Adenosine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000241","descriptor_name":"Adenosine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012323","descriptor_name":"RNA Processing, Post-Transcriptional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012323","descriptor_name":"RNA Processing, Post-Transcriptional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012323","descriptor_name":"RNA Processing, Post-Transcriptional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-019-2840-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-2840-3","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-2840-3","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31046660","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31046660","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:520df5f049174b37a047981646795a6e","is_oa":true,"landing_page_url":"https://doaj.org/article/520df5f049174b37a047981646795a6e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 20, Iss 1, Pp 1-12 (2019)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6498663","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6498663","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-019-2840-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-2840-3","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-2840-3","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1238512391","display_name":null,"funder_award_id":"61501466","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1427182054","display_name":null,"funder_award_id":"16KJB180027","funder_id":"https://openalex.org/F4320321410","funder_display_name":"Jiangsu University"},{"id":"https://openalex.org/G1861567799","display_name":null,"funder_award_id":"XYDXX-118","funder_id":"https://openalex.org/F4320326182","funder_display_name":"Six Talent Peaks Project in Jiangsu Province"},{"id":"https://openalex.org/G2763083788","display_name":null,"funder_award_id":"31671373","funder_id":"https://openalex.org/F4320321410","funder_display_name":"Jiangsu University"},{"id":"https://openalex.org/G4355274439","display_name":null,"funder_award_id":"KSF-T-01","funder_id":"https://openalex.org/F4320324032","funder_display_name":"Xi\u2019an Jiaotong-Liverpool University"},{"id":"https://openalex.org/G4540811719","display_name":null,"funder_award_id":"16KJB180027","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5450572105","display_name":null,"funder_award_id":"31871337","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5709834030","display_name":null,"funder_award_id":"31671373","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321410","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30"},{"id":"https://openalex.org/F4320324032","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05"},{"id":"https://openalex.org/F4320326182","display_name":"Six Talent Peaks Project in Jiangsu Province","ror":null},{"id":"https://openalex.org/F4320335575","display_name":"Key Programme","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2946834045.pdf","grobid_xml":"https://content.openalex.org/works/W2946834045.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W229097380","https://openalex.org/W776567260","https://openalex.org/W1527927437","https://openalex.org/W1764846306","https://openalex.org/W1933156045","https://openalex.org/W1966327575","https://openalex.org/W1973775190","https://openalex.org/W1991807334","https://openalex.org/W2002850151","https://openalex.org/W2007429249","https://openalex.org/W2011131953","https://openalex.org/W2011400542","https://openalex.org/W2022770379","https://openalex.org/W2047515510","https://openalex.org/W2065847836","https://openalex.org/W2085860799","https://openalex.org/W2091724447","https://openalex.org/W2101181377","https://openalex.org/W2102872651","https://openalex.org/W2103017472","https://openalex.org/W2132762486","https://openalex.org/W2138793275","https://openalex.org/W2140729960","https://openalex.org/W2142019735","https://openalex.org/W2163480486","https://openalex.org/W2170219300","https://openalex.org/W2179438025","https://openalex.org/W2180404227","https://openalex.org/W2563912688","https://openalex.org/W2590034108","https://openalex.org/W2612853933","https://openalex.org/W2632544498","https://openalex.org/W2754499625","https://openalex.org/W2761347085","https://openalex.org/W2767731367","https://openalex.org/W2768833223","https://openalex.org/W2769630486","https://openalex.org/W2806565274","https://openalex.org/W2808337257","https://openalex.org/W2883239502","https://openalex.org/W2901239961","https://openalex.org/W2912369228","https://openalex.org/W4230831850"],"related_works":["https://openalex.org/W2214376880","https://openalex.org/W3212149434","https://openalex.org/W2073893804","https://openalex.org/W3215601883","https://openalex.org/W2505116771","https://openalex.org/W2291484187","https://openalex.org/W2902329290","https://openalex.org/W2916807836","https://openalex.org/W4237083789","https://openalex.org/W4308415202"],"abstract_inverted_index":{"Over":[0],"one":[1,31],"hundred":[2],"different":[3],"types":[4],"of":[5,32,43,54,57,70,74,132,193],"post-transcriptional":[6],"RNA":[7,17,25,58,77,97,127,160],"modifications":[8,18],"have":[9],"been":[10],"identified":[11],"in":[12,37,88],"human.":[13],"Researchers":[14],"discovered":[15],"that":[16,150],"can":[19],"regulate":[20],"various":[21],"biological":[22,148,191],"processes,":[23],"and":[24,64],"methylation,":[26,59],"especially":[27],"N6-methyladenosine,":[28],"has":[29],"become":[30],"the":[33,41,52,61,71,92,110,121,126,189,199,205],"most":[34],"researched":[35],"topics":[36],"epigenetics.":[38],"To":[39,80],"date,":[40],"study":[42],"epitranscriptome":[44,112,155,206],"layer":[45,156],"gene":[46,135],"regulation":[47],"is":[48,67,101,212],"mostly":[49],"focused":[50],"on":[51,91,104,167],"function":[53],"mediator":[55],"proteins":[56],"i.e.,":[60],"readers,":[62],"writers":[63],"erasers.":[65],"There":[66],"limited":[68],"investigation":[69],"functional":[72],"relevance":[73],"individual":[75],"m6A":[76,86,111,142,159,194],"methylation":[78,128],"site.":[79],"address":[81],"this,":[82],"we":[83],"annotated":[84],"human":[85,106,141],"sites":[87,143,195,200],"large-scale":[89],"based":[90,103],"guilt-by-association":[93],"principle":[94],"from":[95,125],"an":[96],"co-methylation":[98],"network.":[99],"It":[100],"constructed":[102,183],"public":[105],"MeRIP-Seq":[107],"datasets":[108],"profiling":[109],"under":[113],"32":[114],"independent":[115],"experimental":[116],"conditions.":[117],"By":[118],"systematically":[119],"examining":[120],"network":[122],"characteristics":[123],"obtained":[124],"profiles,":[129],"a":[130,168,174],"total":[131],"339,158":[133],"putative":[134],"ontology":[136],"functions":[137,149,192],"associated":[138],"with":[139],"1446":[140],"were":[144,164],"identified.":[145],"These":[146],"are":[147],"may":[151],"be":[152],"regulated":[153],"at":[154,204],"via":[157],"reversible":[158],"methylation.":[161],"The":[162,208],"results":[163],"further":[165],"validated":[166],"soft":[169],"benchmark":[170],"by":[171],"comparing":[172],"to":[173,184],"random":[175],"predictor.":[176],"An":[177],"online":[178],"web":[179,210],"server":[180,211],"m6Acomet":[181,209],"was":[182],"support":[185],"direct":[186],"query":[187],"for":[188],"predicted":[190],"as":[196,198],"well":[197],"exhibiting":[201],"co-methylated":[202],"patterns":[203],"layer.":[207],"freely":[213],"available":[214],"at:":[215],"www.xjtlu.edu.cn/biologicalsciences/m6acomet":[216],".":[217]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2019-06-07T00:00:00"}