{"id":"https://openalex.org/W2918073486","doi":"https://doi.org/10.1186/s12859-019-2657-0","title":"Functional Heatmap: an automated and interactive pattern recognition tool to integrate time with multi-omics assays","display_name":"Functional Heatmap: an automated and interactive pattern recognition tool to integrate time with multi-omics assays","publication_year":2019,"publication_date":"2019-02-15","ids":{"openalex":"https://openalex.org/W2918073486","doi":"https://doi.org/10.1186/s12859-019-2657-0","mag":"2918073486","pmid":"https://pubmed.ncbi.nlm.nih.gov/30770734"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-019-2657-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-2657-0","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-2657-0","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-2657-0","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053876373","display_name":"Joshua Williams","orcid":null},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I2802821144","display_name":"Center for Environmental Health","ror":"https://ror.org/03k84rm07","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802821144"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joshua R. Williams","raw_affiliation_strings":["Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD, 21702-5010, USA","Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA"],"affiliations":[{"raw_affiliation_string":"Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I2802821144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028447819","display_name":"Ruoting Yang","orcid":"https://orcid.org/0000-0002-8289-1999"},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I2802821144","display_name":"Center for Environmental Health","ror":"https://ror.org/03k84rm07","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802821144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruoting Yang","raw_affiliation_strings":["Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD, 21702-5010, USA","Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA"],"affiliations":[{"raw_affiliation_string":"Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I2802821144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082133160","display_name":"John L. Clifford","orcid":"https://orcid.org/0000-0001-8354-6209"},"institutions":[{"id":"https://openalex.org/I2802821144","display_name":"Center for Environmental Health","ror":"https://ror.org/03k84rm07","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802821144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John L. Clifford","raw_affiliation_strings":["Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA"],"affiliations":[{"raw_affiliation_string":"Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I2802821144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101484754","display_name":"Daniel J. Watson","orcid":"https://orcid.org/0000-0002-3217-3286"},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Watson","raw_affiliation_strings":["Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD, 21702-5010, USA"],"affiliations":[{"raw_affiliation_string":"Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067990677","display_name":"Ross T. Campbell","orcid":"https://orcid.org/0000-0002-0050-2129"},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I2802821144","display_name":"Center for Environmental Health","ror":"https://ror.org/03k84rm07","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802821144"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ross Campbell","raw_affiliation_strings":["Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD, 21702-5010, USA","Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA"],"affiliations":[{"raw_affiliation_string":"Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I2802821144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015742394","display_name":"Derese Getnet","orcid":"https://orcid.org/0000-0002-2619-4910"},"institutions":[{"id":"https://openalex.org/I2802821144","display_name":"Center for Environmental Health","ror":"https://ror.org/03k84rm07","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802821144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Derese Getnet","raw_affiliation_strings":["Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA"],"affiliations":[{"raw_affiliation_string":"Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I2802821144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054996087","display_name":"Raina Kumar","orcid":"https://orcid.org/0000-0002-7090-0691"},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I2802821144","display_name":"Center for Environmental Health","ror":"https://ror.org/03k84rm07","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802821144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raina Kumar","raw_affiliation_strings":["Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD, 21702-5010, USA","Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA"],"affiliations":[{"raw_affiliation_string":"Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I2802821144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082731692","display_name":"Rasha Hammamieh","orcid":"https://orcid.org/0000-0001-8643-6232"},"institutions":[{"id":"https://openalex.org/I2802821144","display_name":"Center for Environmental Health","ror":"https://ror.org/03k84rm07","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802821144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rasha Hammamieh","raw_affiliation_strings":["Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA"],"affiliations":[{"raw_affiliation_string":"Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I2802821144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004751787","display_name":"Marti Jett","orcid":"https://orcid.org/0000-0002-2899-0216"},"institutions":[{"id":"https://openalex.org/I2802821144","display_name":"Center for Environmental Health","ror":"https://ror.org/03k84rm07","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802821144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marti Jett","raw_affiliation_strings":["Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA. marti.jett-tilton.civ@mail.mil","Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA"],"affiliations":[{"raw_affiliation_string":"Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA. marti.jett-tilton.civ@mail.mil","institution_ids":[]},{"raw_affiliation_string":"Integrative Systems Biology Program, US Army Center for Environmental Health Research, Fort Detrick, Frederick, MD, 21702-5010, USA","institution_ids":["https://openalex.org/I2802821144"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5053876373"],"corresponding_institution_ids":["https://openalex.org/I2802821144","https://openalex.org/I4210130649","https://openalex.org/I4210140884"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.7225,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.84597186,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"20","issue":"1","first_page":"81","last_page":"81"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6660911440849304},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5214568972587585},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.47400057315826416},{"id":"https://openalex.org/keywords/interface","display_name":"Interface (matter)","score":0.42533156275749207},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.41473981738090515},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.41252022981643677},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3838478922843933},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3685646057128906},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.35690730810165405},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.333102285861969},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.17417725920677185}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6660911440849304},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5214568972587585},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.47400057315826416},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.42533156275749207},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.41473981738090515},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.41252022981643677},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3838478922843933},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3685646057128906},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.35690730810165405},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.333102285861969},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17417725920677185},{"id":"https://openalex.org/C129307140","wikidata":"https://www.wikidata.org/wiki/Q6795880","display_name":"Maximum bubble pressure method","level":3,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C173608175","wikidata":"https://www.wikidata.org/wiki/Q232661","display_name":"Parallel computing","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C157915830","wikidata":"https://www.wikidata.org/wiki/Q2928001","display_name":"Bubble","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011839","descriptor_name":"Radiation, Ionizing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011839","descriptor_name":"Radiation, Ionizing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011839","descriptor_name":"Radiation, Ionizing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011839","descriptor_name":"Radiation, Ionizing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011839","descriptor_name":"Radiation, Ionizing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12859-019-2657-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-2657-0","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-2657-0","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:30770734","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30770734","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:7defff1683874778a765f5870c1d8be4","is_oa":true,"landing_page_url":"https://doaj.org/article/7defff1683874778a765f5870c1d8be4","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 20, Iss 1, Pp 1-6 (2019)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:5380556","is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6377781","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6377781","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6377781","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-019-2657-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-019-2657-0","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-2657-0","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5299999713897705,"id":"https://metadata.un.org/sdg/8","display_name":"Decent work and economic growth"}],"awards":[{"id":"https://openalex.org/G7643671341","display_name":null,"funder_award_id":"09284002","funder_id":"https://openalex.org/F4320338280","funder_display_name":"Medical Research and Materiel Command"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320338280","display_name":"Medical Research and Materiel Command","ror":"https://ror.org/03cd02q50"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2918073486.pdf","grobid_xml":"https://content.openalex.org/works/W2918073486.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1964692421","https://openalex.org/W1974120932","https://openalex.org/W2029485495","https://openalex.org/W2035240455","https://openalex.org/W2055550250","https://openalex.org/W2101142880","https://openalex.org/W2101222094","https://openalex.org/W2109521384","https://openalex.org/W2130410032","https://openalex.org/W2140703956","https://openalex.org/W2144738674","https://openalex.org/W2147714160","https://openalex.org/W2150926065","https://openalex.org/W2159482845","https://openalex.org/W2579728701","https://openalex.org/W2767914218","https://openalex.org/W4242404314","https://openalex.org/W4294216483"],"related_works":["https://openalex.org/W2068608913","https://openalex.org/W3124914020","https://openalex.org/W2141033859","https://openalex.org/W2077542787","https://openalex.org/W2156434174","https://openalex.org/W2071701083","https://openalex.org/W2383687187","https://openalex.org/W2121496884","https://openalex.org/W2387910809","https://openalex.org/W2294221496"],"abstract_inverted_index":{"Functional":[0],"Heatmap":[1],"is":[2],"an":[3],"automated":[4],"and":[5,25],"interactive":[6],"tool":[7],"that":[8],"enables":[9],"pattern":[10,23,36],"recognition":[11,37],"in":[12],"time-series":[13,53],"multi-omics":[14],"assays.":[15,57],"It":[16],"significantly":[17],"reduces":[18],"the":[19],"manual":[20],"labour":[21],"of":[22],"discovery":[24],"comparison":[26],"by":[27,46],"transferring":[28],"statistical":[29],"models":[30],"into":[31],"visual":[32],"clues.":[33],"The":[34],"new":[35],"feature":[38],"will":[39],"help":[40],"researchers":[41],"identify":[42],"hidden":[43],"trends":[44],"driven":[45],"functional":[47],"changes":[48],"using":[49],"multi-tissues/conditions":[50],"on":[51],"a":[52],"fashion":[54],"from":[55],"omic":[56]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":3}],"updated_date":"2026-03-05T09:29:38.588285","created_date":"2025-10-10T00:00:00"}