{"id":"https://openalex.org/W2766029068","doi":"https://doi.org/10.1186/s12859-017-1827-1","title":"VAliBS: a visual aligner for bisulfite sequences","display_name":"VAliBS: a visual aligner for bisulfite sequences","publication_year":2017,"publication_date":"2017-10-01","ids":{"openalex":"https://openalex.org/W2766029068","doi":"https://doi.org/10.1186/s12859-017-1827-1","mag":"2766029068","pmid":"https://pubmed.ncbi.nlm.nih.gov/29072146"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-017-1827-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-017-1827-1","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-017-1827-1","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-017-1827-1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100719013","display_name":"Min Li","orcid":"https://orcid.org/0000-0002-0188-1394"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Li","raw_affiliation_strings":["School of Information Science and Engineering, Central South University, Changsha, 410083, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Engineering, Central South University, Changsha, 410083, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100778681","display_name":"Ping Huang","orcid":"https://orcid.org/0000-0002-1012-9997"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Huang","raw_affiliation_strings":["School of Information Science and Engineering, Central South University, Changsha, 410083, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Engineering, Central South University, Changsha, 410083, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018151914","display_name":"Xiaodong Yan","orcid":"https://orcid.org/0000-0003-4971-6731"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaodong Yan","raw_affiliation_strings":["School of Information Science and Engineering, Central South University, Changsha, 410083, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Engineering, Central South University, Changsha, 410083, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100438360","display_name":"Jianxin Wang","orcid":"https://orcid.org/0000-0003-1516-0480"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jianxin Wang","raw_affiliation_strings":["School of Information Science and Engineering, Central South University, Changsha, 410083, China. jxwang@mail.csu.edu.cn","School of Information Science and Engineering, Central South University, Changsha, 410083, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Engineering, Central South University, Changsha, 410083, China. jxwang@mail.csu.edu.cn","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"School of Information Science and Engineering, Central South University, Changsha, 410083, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101465265","display_name":"Yi Pan","orcid":"https://orcid.org/0000-0002-2766-3096"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Yi Pan","raw_affiliation_strings":["Department of Computer Science, Georgia State University, Atlanta, GA, 30302-4110, USA. yipan@gsu.edu","School of Information Science and Engineering, Central South University, Changsha, 410083, China. yipan@gsu.edu","School of Information Science and Engineering, Central South University, Changsha, 410083, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Georgia State University, Atlanta, GA, 30302-4110, USA. yipan@gsu.edu","institution_ids":["https://openalex.org/I181565077"]},{"raw_affiliation_string":"School of Information Science and Engineering, Central South University, Changsha, 410083, China. yipan@gsu.edu","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"School of Information Science and Engineering, Central South University, Changsha, 410083, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091157395","display_name":"Fang\u2010Xiang Wu","orcid":"https://orcid.org/0000-0002-4593-9332"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I32625721","display_name":"University of Saskatchewan","ror":"https://ror.org/010x8gc63","country_code":"CA","type":"education","lineage":["https://openalex.org/I32625721"]}],"countries":["CA","CN"],"is_corresponding":false,"raw_author_name":"Fang-Xiang Wu","raw_affiliation_strings":["Division of Biomedical Engineering and Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, SK, S7N 5A9, Canada","School of Information Science and Engineering, Central South University, Changsha, 410083, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biomedical Engineering and Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, SK, S7N 5A9, Canada","institution_ids":["https://openalex.org/I32625721"]},{"raw_affiliation_string":"School of Information Science and Engineering, Central South University, Changsha, 410083, China","institution_ids":["https://openalex.org/I139660479"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100438360","https://openalex.org/A5101465265"],"corresponding_institution_ids":["https://openalex.org/I139660479","https://openalex.org/I181565077"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2790},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2790},"fwci":0.1013,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.48076587,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"18","issue":"S12","first_page":"410","last_page":"410"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.8007000088691711,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.8007000088691711,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.0272000003606081,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.025499999523162842,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bisulfite","display_name":"Bisulfite","score":0.8289037942886353},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7003737092018127},{"id":"https://openalex.org/keywords/bisulfite-sequencing","display_name":"Bisulfite sequencing","score":0.5399084687232971},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.5312908291816711},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5217947959899902},{"id":"https://openalex.org/keywords/methylation","display_name":"Methylation","score":0.5020921230316162},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.454972505569458},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.26985329389572144},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.26310300827026367},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.21348300576210022},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.19888615608215332},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.07728105783462524}],"concepts":[{"id":"https://openalex.org/C2775959680","wikidata":"https://www.wikidata.org/wiki/Q2718222","display_name":"Bisulfite","level":5,"score":0.8289037942886353},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7003737092018127},{"id":"https://openalex.org/C189235521","wikidata":"https://www.wikidata.org/wiki/Q4087270","display_name":"Bisulfite sequencing","level":5,"score":0.5399084687232971},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.5312908291816711},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5217947959899902},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.5020921230316162},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.454972505569458},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.26985329389572144},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.26310300827026367},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21348300576210022},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19888615608215332},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07728105783462524},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013447","descriptor_name":"Sulfites","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013447","descriptor_name":"Sulfites","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013447","descriptor_name":"Sulfites","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-017-1827-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-017-1827-1","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-017-1827-1","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:29072146","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29072146","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:8670f0e3fa7c4058a4b9fc82bb2786fe","is_oa":false,"landing_page_url":"https://doaj.org/article/8670f0e3fa7c4058a4b9fc82bb2786fe","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 18, Iss S12, Pp 91-98 (2017)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4583249","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5657078","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-017-1827-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-017-1827-1","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-017-1827-1","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2449283814","display_name":null,"funder_award_id":"No. 61379108","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3461952442","display_name":null,"funder_award_id":"No. 61232001","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8223640893","display_name":null,"funder_award_id":"61232001","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8478685728","display_name":null,"funder_award_id":"61379108","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2766029068.pdf","grobid_xml":"https://content.openalex.org/works/W2766029068.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W299332718","https://openalex.org/W1657324220","https://openalex.org/W1963590871","https://openalex.org/W1968258442","https://openalex.org/W1987760376","https://openalex.org/W1990937720","https://openalex.org/W2012703624","https://openalex.org/W2040507896","https://openalex.org/W2041674913","https://openalex.org/W2050077513","https://openalex.org/W2051273886","https://openalex.org/W2051465150","https://openalex.org/W2053309035","https://openalex.org/W2061076014","https://openalex.org/W2070339716","https://openalex.org/W2094471257","https://openalex.org/W2096441981","https://openalex.org/W2102868331","https://openalex.org/W2103441770","https://openalex.org/W2106889224","https://openalex.org/W2119270998","https://openalex.org/W2124985265","https://openalex.org/W2128793361","https://openalex.org/W2131374955","https://openalex.org/W2133229506","https://openalex.org/W2136186510","https://openalex.org/W2139760555","https://openalex.org/W2145095977","https://openalex.org/W2149414426","https://openalex.org/W2157539385","https://openalex.org/W2158774461","https://openalex.org/W2161315819","https://openalex.org/W2170551349","https://openalex.org/W2330617919","https://openalex.org/W2336321619","https://openalex.org/W2520464109","https://openalex.org/W2610924493","https://openalex.org/W4247053599","https://openalex.org/W4298858744"],"related_works":["https://openalex.org/W2805216920","https://openalex.org/W2619376220","https://openalex.org/W2064302386","https://openalex.org/W2134949149","https://openalex.org/W2035236309","https://openalex.org/W2895945844","https://openalex.org/W2033196363","https://openalex.org/W1964177829","https://openalex.org/W2911544435","https://openalex.org/W1991992597"],"abstract_inverted_index":{"BACKGROUND:":[0],"Methylation":[1],"is":[2,117],"a":[3,11,71,83,118,153],"common":[4],"modification":[5],"of":[6,29,112,149,161,163],"DNA.":[7],"It":[8,177],"has":[9],"been":[10],"very":[12],"important":[13],"and":[14,23,73,127,146,152,174,197],"hot":[15],"topic":[16],"to":[17,63,82,140,157],"study":[18],"the":[19,30,58,110,128,159,192,198],"correlation":[20],"between":[21],"methylation":[22,45,183,193],"diseases":[24],"in":[25,181],"medical":[26],"science.":[27],"Because":[28],"special":[31],"process":[32],"with":[33,43,100,133],"bisulfite":[34,113],"treatment,":[35],"traditional":[36],"mapping":[37,54,79,148,162],"tools":[38,103],"do":[39],"not":[40,51],"work":[41],"well":[42,88,169],"such":[44],"experimental":[46],"reads.":[47],"Traditional":[48],"aligners":[49],"are":[50,61,131,195,200],"designed":[52],"for":[53,78],"bisulfite-treated":[55],"reads,":[56,151],"where":[57,191],"un-methylated":[59],"'C's":[60],"converted":[62],"'T's.":[64],"RESULTS:":[65],"In":[66],"this":[67],"paper,":[68],"we":[69],"develop":[70],"reliable":[72],"visual":[74,119,196],"tool,":[75],"named":[76],"VAliBS,":[77],"bisulfate":[80],"sequences":[81],"genome":[84],"reference.":[85],"VAliBS":[86,107,116,143,167],"works":[87,168],"even":[89],"on":[90,170],"large":[91],"scale":[92],"data":[93,173],"or":[94],"high":[95],"noise":[96],"data.":[97,176],"By":[98],"comparing":[99],"other":[101],"state-of-the-art":[102],"(BisMark,":[104],"BSMAP,":[105],"BS-Seeker2),":[106],"can":[108,178],"improve":[109],"accuracy":[111],"mapping.":[114],"Moreover,":[115],"tool":[120],"which":[121,136],"makes":[122,137],"its":[123],"operations":[124,199],"more":[125],"easily":[126],"alignment":[129],"results":[130],"shown":[132],"colored":[134],"marks":[135],"it":[138],"easier":[139],"be":[141,179],"read.":[142,165],"provides":[144],"fast":[145],"accurate":[147],"bisulfite-converted":[150],"friendly":[154],"window":[155],"system":[156],"visualize":[158],"detail":[160],"each":[164],"CONCLUSIONS:":[166],"both":[171],"simulated":[172],"real":[175],"useful":[180],"DNA":[182],"research.":[184],"VALiBS":[185],"implements":[186],"an":[187],"X-Window":[188],"user":[189],"interface":[190],"positions":[194],"friendly.":[201]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}