{"id":"https://openalex.org/W2598774641","doi":"https://doi.org/10.1186/s12859-017-1475-5","title":"Improving prediction of burial state of residues by exploiting correlation among residues","display_name":"Improving prediction of burial state of residues by exploiting correlation among residues","publication_year":2017,"publication_date":"2017-03-01","ids":{"openalex":"https://openalex.org/W2598774641","doi":"https://doi.org/10.1186/s12859-017-1475-5","mag":"2598774641","pmid":"https://pubmed.ncbi.nlm.nih.gov/28361691"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-017-1475-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-017-1475-5","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-017-1475-5","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-017-1475-5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083227730","display_name":"Hai\u2019e Gong","orcid":null},"institutions":[{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hai\u2019e Gong","raw_affiliation_strings":["Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China","School of Computer Science, University of Chinese Academy of Sciences, Beijing, China","Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]},{"raw_affiliation_string":"School of Computer Science, University of Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210165038"]},{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060273621","display_name":"Haicang Zhang","orcid":"https://orcid.org/0000-0001-6268-4258"},"institutions":[{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haicang Zhang","raw_affiliation_strings":["Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China","School of Computer Science, University of Chinese Academy of Sciences, Beijing, China","Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]},{"raw_affiliation_string":"School of Computer Science, University of Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210165038"]},{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053196390","display_name":"Jianwei Zhu","orcid":"https://orcid.org/0000-0002-8272-9190"},"institutions":[{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianwei Zhu","raw_affiliation_strings":["Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China","School of Computer Science, University of Chinese Academy of Sciences, Beijing, China","Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]},{"raw_affiliation_string":"School of Computer Science, University of Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210165038"]},{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100406986","display_name":"Chao Wang","orcid":"https://orcid.org/0000-0002-4316-8124"},"institutions":[{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Wang","raw_affiliation_strings":["Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China","School of Computer Science, University of Chinese Academy of Sciences, Beijing, China","Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]},{"raw_affiliation_string":"School of Computer Science, University of Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210165038"]},{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108903761","display_name":"Shiwei Sun","orcid":"https://orcid.org/0000-0002-0351-3720"},"institutions":[{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shiwei Sun","raw_affiliation_strings":["Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China","Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021041719","display_name":"Wei\u2010Mou Zheng","orcid":"https://orcid.org/0000-0001-6546-2917"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210125404","display_name":"Institute of Theoretical Physics","ror":"https://ror.org/02xtbq882","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210125404"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wei-Mou Zheng","raw_affiliation_strings":["Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing, 100190, China. zheng@itp.ac.cn","Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing, 100190, China. zheng@itp.ac.cn","institution_ids":[]},{"raw_affiliation_string":"Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210125404","https://openalex.org/I19820366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076729236","display_name":"Dongbo Bu","orcid":"https://orcid.org/0000-0003-4119-4238"},"institutions":[{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dongbo Bu","raw_affiliation_strings":["Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China. dbu@ict.ac.cn","Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China. dbu@ict.ac.cn","institution_ids":[]},{"raw_affiliation_string":"Key Lab of Intelligent Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5021041719","https://openalex.org/A5076729236"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210090176","https://openalex.org/I4210125404"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.1014,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.45324815,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"18","issue":"S3","first_page":"70","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9383000135421753,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9383000135421753,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.02930000051856041,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/correlation","display_name":"Correlation","score":0.5803464651107788},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.5035976767539978},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4671356678009033},{"id":"https://openalex.org/keywords/state","display_name":"State (computer science)","score":0.4357345700263977},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3880614638328552},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.30167877674102783},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2658901810646057},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.26205193996429443},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.13416531682014465},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.09809660911560059},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.07081213593482971}],"concepts":[{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.5803464651107788},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.5035976767539978},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4671356678009033},{"id":"https://openalex.org/C48103436","wikidata":"https://www.wikidata.org/wiki/Q599031","display_name":"State (computer science)","level":2,"score":0.4357345700263977},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3880614638328552},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30167877674102783},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2658901810646057},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.26205193996429443},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.13416531682014465},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09809660911560059},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.07081213593482971},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057927","descriptor_name":"Hydrophobic and Hydrophilic Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057927","descriptor_name":"Hydrophobic and Hydrophilic Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057927","descriptor_name":"Hydrophobic and Hydrophilic Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1186/s12859-017-1475-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-017-1475-5","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-017-1475-5","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:28361691","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28361691","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:5374591","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5374591","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-017-1475-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-017-1475-5","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-017-1475-5","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1434303207","display_name":null,"funder_award_id":"11175224","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1617341002","display_name":null,"funder_award_id":"11121403","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3888631583","display_name":"\u86cb\u767d\u8d28\u7ed3\u6784\u6a21\u4f53\u8bc6\u522b\u53ca\u7ed3\u6784\u9884\u6d4b\u7b97\u6cd5\u7814\u7a76","funder_award_id":"61272318","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6651447324","display_name":null,"funder_award_id":"31671369","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7814778640","display_name":null,"funder_award_id":"31270834","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G795020757","display_name":null,"funder_award_id":"2012CB316502","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2598774641.pdf","grobid_xml":"https://content.openalex.org/works/W2598774641.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W157808733","https://openalex.org/W596647800","https://openalex.org/W1543987512","https://openalex.org/W1596947964","https://openalex.org/W1603325468","https://openalex.org/W1964062873","https://openalex.org/W1981387027","https://openalex.org/W1987100568","https://openalex.org/W2001900040","https://openalex.org/W2004360551","https://openalex.org/W2005750609","https://openalex.org/W2009570821","https://openalex.org/W2050625197","https://openalex.org/W2061663059","https://openalex.org/W2065292510","https://openalex.org/W2070783701","https://openalex.org/W2071834506","https://openalex.org/W2076052898","https://openalex.org/W2096495474","https://openalex.org/W2096773908","https://openalex.org/W2099886875","https://openalex.org/W2106116715","https://openalex.org/W2109502170","https://openalex.org/W2111705855","https://openalex.org/W2123957843","https://openalex.org/W2125158282","https://openalex.org/W2131474431","https://openalex.org/W2134447775","https://openalex.org/W2142529984","https://openalex.org/W2142808579","https://openalex.org/W2144316442","https://openalex.org/W2146496445","https://openalex.org/W2147209844","https://openalex.org/W2147880316","https://openalex.org/W2150346640","https://openalex.org/W2150627302","https://openalex.org/W2158714788","https://openalex.org/W2161005920","https://openalex.org/W2165777467","https://openalex.org/W2284132962","https://openalex.org/W2963457143","https://openalex.org/W4245668478"],"related_works":["https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189","https://openalex.org/W1971568933","https://openalex.org/W2013243191","https://openalex.org/W2117258802"],"abstract_inverted_index":{"BACKGROUND:":[0],"Residues":[1],"in":[2,101,138],"a":[3,88,102],"protein":[4,39,103,186],"might":[5],"be":[6],"buried":[7,18],"inside":[8],"or":[9],"exposed":[10,33],"to":[11,24,38],"the":[12,15,26,32,42,64,69,78,110,117,128,135,149,153,157,175],"solvent":[13,46],"surrounding":[14],"protein.":[16],"The":[17],"residues":[19,34,49,100,114],"usually":[20],"form":[21],"hydrophobic":[22],"cores":[23],"maintain":[25],"structural":[27],"integrity":[28],"of":[29,45,48,55,60,63,72,98,178],"proteins":[30],"while":[31],"are":[35],"tightly":[36],"related":[37],"functions.":[40],"Thus,":[41],"accurate":[43,176],"prediction":[44,66,139,177,188],"accessibility":[47],"will":[50],"greatly":[51,184],"facilitate":[52,185],"our":[53,132],"understanding":[54],"both":[56],"structure":[57,187],"and":[58,162,189],"functionalities":[59],"proteins.":[61],"Most":[62],"state-of-the-art":[65,136],"approaches":[67,137],"consider":[68],"burial":[70,96,180],"state":[71],"each":[73],"residue":[74,179],"independently,":[75],"thus":[76],"neglecting":[77],"correlations":[79],"among":[80,112,119,130],"residues.":[81,121],"RESULTS:":[82],"In":[83],"this":[84],"study,":[85],"we":[86],"present":[87],"high-order":[89,150],"conditional":[90,164],"random":[91,165],"field":[92,166],"model":[93],"that":[94,125,146],"considers":[95],"states":[97],"all":[99],"simultaneously.":[104],"Our":[105,172],"approach":[106,133],"exploits":[107],"not":[108],"only":[109],"correlation":[111,118,129],"adjacent":[113],"but":[115],"also":[116,144],"long-range":[120],"Experimental":[122],"results":[123],"showed":[124,145],"by":[126,147,156],"exploiting":[127],"residues,":[131],"outperformed":[134],"accuracy.":[140],"In-depth":[141],"case":[142],"studies":[143],"using":[148],"statistical":[151],"model,":[152],"errors":[154],"committed":[155],"bidirectional":[158],"recurrent":[159],"neural":[160],"network":[161],"chain":[163],"models":[167],"were":[168],"successfully":[169],"corrected.":[170],"CONCLUSIONS:":[171],"methods":[173],"enable":[174],"states,":[181],"which":[182],"should":[183],"evaluation.":[190]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-07-15T18:14:33.161393","created_date":"2025-10-10T00:00:00"}
