{"id":"https://openalex.org/W2564980658","doi":"https://doi.org/10.1186/s12859-016-1414-x","title":"Bon-EV: an improved multiple testing procedure for controlling false discovery rates","display_name":"Bon-EV: an improved multiple testing procedure for controlling false discovery rates","publication_year":2017,"publication_date":"2017-01-03","ids":{"openalex":"https://openalex.org/W2564980658","doi":"https://doi.org/10.1186/s12859-016-1414-x","mag":"2564980658","pmid":"https://pubmed.ncbi.nlm.nih.gov/28049414"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-016-1414-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1414-x","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1414-x","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1414-x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100417601","display_name":"Dongmei Li","orcid":"https://orcid.org/0000-0001-9140-2483"},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medical Center","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dongmei Li","raw_affiliation_strings":["Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, 265 Crittenden Boulevard CU 420708, Rochester, 14642, NY, USA. dongmei_li@urmc.rochester.edu","Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, 265 Crittenden Boulevard CU 420708, Rochester, 14642, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-9140-2483","affiliations":[{"raw_affiliation_string":"Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, 265 Crittenden Boulevard CU 420708, Rochester, 14642, NY, USA. dongmei_li@urmc.rochester.edu","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"raw_affiliation_string":"Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, 265 Crittenden Boulevard CU 420708, Rochester, 14642, NY, USA","institution_ids":["https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062141420","display_name":"Zidian Xie","orcid":"https://orcid.org/0000-0002-5149-7710"},"institutions":[{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zidian Xie","raw_affiliation_strings":["Goergen Institute for Data Science, University of Rochester, Computer Studies Building, Rochester, 14642, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Goergen Institute for Data Science, University of Rochester, Computer Studies Building, Rochester, 14642, NY, USA","institution_ids":["https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076140837","display_name":"Martin S. Zand","orcid":"https://orcid.org/0000-0002-7095-8682"},"institutions":[{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin Zand","raw_affiliation_strings":["Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, 265 Crittenden Boulevard CU 420708, Rochester, 14642, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, 265 Crittenden Boulevard CU 420708, Rochester, 14642, NY, USA","institution_ids":["https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005513910","display_name":"Thomas T. Fogg","orcid":null},"institutions":[{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Fogg","raw_affiliation_strings":["Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, 265 Crittenden Boulevard CU 420708, Rochester, 14642, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, 265 Crittenden Boulevard CU 420708, Rochester, 14642, NY, USA","institution_ids":["https://openalex.org/I5388228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014004464","display_name":"Timothy Dye","orcid":"https://orcid.org/0000-0002-9801-4712"},"institutions":[{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy Dye","raw_affiliation_strings":["Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, 265 Crittenden Boulevard CU 420708, Rochester, 14642, NY, USA","Department of Obstetrics and Gynecology, University of Rochester, 500 Red Creek Drive Suite 220, Rochester, 14623, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, 265 Crittenden Boulevard CU 420708, Rochester, 14642, NY, USA","institution_ids":["https://openalex.org/I5388228"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Rochester, 500 Red Creek Drive Suite 220, Rochester, 14623, NY, USA","institution_ids":["https://openalex.org/I5388228"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100417601"],"corresponding_institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":4.3671,"has_fulltext":true,"cited_by_count":232,"citation_normalized_percentile":{"value":0.95257204,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"18","issue":"1","first_page":"1","last_page":"1"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.37220001220703125,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.37220001220703125,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.24480000138282776,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.11710000038146973,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/false-discovery-rate","display_name":"False discovery rate","score":0.9005409479141235},{"id":"https://openalex.org/keywords/multiple-comparisons-problem","display_name":"Multiple comparisons problem","score":0.8876799941062927},{"id":"https://openalex.org/keywords/bonferroni-correction","display_name":"Bonferroni correction","score":0.7781107425689697},{"id":"https://openalex.org/keywords/sample-size-determination","display_name":"Sample size determination","score":0.6893295049667358},{"id":"https://openalex.org/keywords/stability","display_name":"Stability (learning theory)","score":0.6675403714179993},{"id":"https://openalex.org/keywords/consistency","display_name":"Consistency (knowledge bases)","score":0.6427489519119263},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.5058991312980652},{"id":"https://openalex.org/keywords/standard-deviation","display_name":"Standard deviation","score":0.49449703097343445},{"id":"https://openalex.org/keywords/value","display_name":"Value (mathematics)","score":0.4878373444080353},{"id":"https://openalex.org/keywords/power","display_name":"Power (physics)","score":0.4747510254383087},{"id":"https://openalex.org/keywords/p-value","display_name":"p-value","score":0.47278428077697754},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4542529881000519},{"id":"https://openalex.org/keywords/sample","display_name":"Sample (material)","score":0.4130327105522156},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.4001384675502777},{"id":"https://openalex.org/keywords/statistical-hypothesis-testing","display_name":"Statistical hypothesis testing","score":0.39633190631866455},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.33822759985923767},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.14828228950500488},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.11919251084327698},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.10111621022224426},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.07792782783508301},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.07728952169418335},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.07726451754570007}],"concepts":[{"id":"https://openalex.org/C193244246","wikidata":"https://www.wikidata.org/wiki/Q5432696","display_name":"False discovery rate","level":3,"score":0.9005409479141235},{"id":"https://openalex.org/C183905921","wikidata":"https://www.wikidata.org/wiki/Q1038757","display_name":"Multiple comparisons problem","level":2,"score":0.8876799941062927},{"id":"https://openalex.org/C127808970","wikidata":"https://www.wikidata.org/wiki/Q385989","display_name":"Bonferroni correction","level":2,"score":0.7781107425689697},{"id":"https://openalex.org/C129848803","wikidata":"https://www.wikidata.org/wiki/Q2564360","display_name":"Sample size determination","level":2,"score":0.6893295049667358},{"id":"https://openalex.org/C112972136","wikidata":"https://www.wikidata.org/wiki/Q7595718","display_name":"Stability (learning theory)","level":2,"score":0.6675403714179993},{"id":"https://openalex.org/C2776436953","wikidata":"https://www.wikidata.org/wiki/Q5163215","display_name":"Consistency (knowledge bases)","level":2,"score":0.6427489519119263},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.5058991312980652},{"id":"https://openalex.org/C22679943","wikidata":"https://www.wikidata.org/wiki/Q159375","display_name":"Standard deviation","level":2,"score":0.49449703097343445},{"id":"https://openalex.org/C2776291640","wikidata":"https://www.wikidata.org/wiki/Q2912517","display_name":"Value (mathematics)","level":2,"score":0.4878373444080353},{"id":"https://openalex.org/C163258240","wikidata":"https://www.wikidata.org/wiki/Q25342","display_name":"Power (physics)","level":2,"score":0.4747510254383087},{"id":"https://openalex.org/C44036329","wikidata":"https://www.wikidata.org/wiki/Q253255","display_name":"p-value","level":3,"score":0.47278428077697754},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4542529881000519},{"id":"https://openalex.org/C198531522","wikidata":"https://www.wikidata.org/wiki/Q485146","display_name":"Sample (material)","level":2,"score":0.4130327105522156},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.4001384675502777},{"id":"https://openalex.org/C87007009","wikidata":"https://www.wikidata.org/wiki/Q210832","display_name":"Statistical hypothesis testing","level":2,"score":0.39633190631866455},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.33822759985923767},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14828228950500488},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.11919251084327698},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10111621022224426},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.07792782783508301},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.07728952169418335},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.07726451754570007},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1186/s12859-016-1414-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1414-x","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1414-x","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:28049414","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28049414","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:5210267","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5210267","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-016-1414-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1414-x","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1414-x","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1744262647","display_name":null,"funder_award_id":"AI069351","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G3343546770","display_name":null,"funder_award_id":"UL1 TR002001","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3380008563","display_name":null,"funder_award_id":"AI069351","funder_id":"https://openalex.org/F4320310246","funder_display_name":"University of Rochester"},{"id":"https://openalex.org/G3497421373","display_name":null,"funder_award_id":"UL1 TR000042","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G4411448324","display_name":null,"funder_award_id":"UL1 TR002001","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G476718775","display_name":null,"funder_award_id":"TR000042","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5623077204","display_name":null,"funder_award_id":"AI098112","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G625544220","display_name":null,"funder_award_id":"UL1 TR002001","funder_id":"https://openalex.org/F4320310246","funder_display_name":"University of Rochester"},{"id":"https://openalex.org/G6422398712","display_name":null,"funder_award_id":"TR002001","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G674291738","display_name":null,"funder_award_id":"TR002001","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G700200469","display_name":null,"funder_award_id":"TR002001","funder_id":"https://openalex.org/F4320310246","funder_display_name":"University of Rochester"},{"id":"https://openalex.org/G7112637443","display_name":null,"funder_award_id":"AI098112","funder_id":"https://openalex.org/F4320310246","funder_display_name":"University of Rochester"},{"id":"https://openalex.org/G7313541307","display_name":null,"funder_award_id":"UL1 TR000042","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7979507054","display_name":null,"funder_award_id":"AI098112","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7982150927","display_name":null,"funder_award_id":"AI069351","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8390411406","display_name":null,"funder_award_id":"UL1 TR000042","funder_id":"https://openalex.org/F4320310246","funder_display_name":"University of Rochester"}],"funders":[{"id":"https://openalex.org/F4320310040","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967"},{"id":"https://openalex.org/F4320310246","display_name":"University of Rochester","ror":"https://ror.org/022kthw22"},{"id":"https://openalex.org/F4320316438","display_name":"Georgia Clinical and Translational Science Alliance","ror":null},{"id":"https://openalex.org/F4320327259","display_name":"National Institute of Immunology","ror":"https://ror.org/04fhee747"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2564980658.pdf","grobid_xml":"https://content.openalex.org/works/W2564980658.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W402080065","https://openalex.org/W1505461723","https://openalex.org/W1970047903","https://openalex.org/W1980181946","https://openalex.org/W1987777080","https://openalex.org/W1996984681","https://openalex.org/W1997917263","https://openalex.org/W2022590976","https://openalex.org/W2052386819","https://openalex.org/W2072602203","https://openalex.org/W2105381419","https://openalex.org/W2107018762","https://openalex.org/W2110065044","https://openalex.org/W2113330311","https://openalex.org/W2114104545","https://openalex.org/W2119185338","https://openalex.org/W2125905177","https://openalex.org/W2126645252","https://openalex.org/W2143079975","https://openalex.org/W2144441730","https://openalex.org/W2147278423","https://openalex.org/W3103900655","https://openalex.org/W4205210034","https://openalex.org/W4249665717"],"related_works":["https://openalex.org/W2093104131","https://openalex.org/W4293336298","https://openalex.org/W2333750400","https://openalex.org/W2467227750","https://openalex.org/W2178204436","https://openalex.org/W4300887971","https://openalex.org/W4212966421","https://openalex.org/W1921844237","https://openalex.org/W154531455","https://openalex.org/W1976797354"],"abstract_inverted_index":{"BACKGROUND:":[0],"Stability":[1],"of":[2,11,14,22,24,30,40,81,127,148],"multiple":[3,25,31,54,98,255],"testing":[4,26,32,55,99,256],"procedures,":[5],"defined":[6],"as":[7,19,260],"the":[8,38,79,124,128,187,191,201,208,220,230,241,250,261],"standard":[9],"deviation":[10],"total":[12],"number":[13],"discoveries,":[15],"can":[16,34,122],"be":[17],"used":[18,53],"an":[20],"indicator":[21],"variability":[23],"procedures.":[27],"Improving":[28],"stability":[29,72,80,141,206,238],"procedures":[33,49,56],"help":[35],"to":[36,103],"increase":[37],"consistency":[39],"findings":[41],"from":[42],"replicated":[43],"experiments.":[44],"Benjamini-Hochberg's":[45,74,221],"and":[46,70,85,132,139,154,190,216,237,245],"Storey's":[47,64,82,129,143,192,209,242],"q-value":[48,65,83,130,144,193,210,243],"are":[50],"two":[51],"commonly":[52],"for":[57,146,161,266],"controlling":[58],"false":[59,105],"discoveries":[60],"in":[61,90,135,151,158,177,264],"genomic":[62,91],"studies.":[63],"procedure":[66,84,121,131,145,183,189,203,211,232,244,257],"has":[67,184,204,233],"higher":[68,140,205,217],"power":[69,89,126,218,247],"lower":[71],"than":[73,142,207,219],"procedure.":[75,194,222,252],"To":[76],"improve":[77],"upon":[78],"maintain":[86,123],"its":[87],"high":[88,125],"data":[92,198],"analysis,":[93],"we":[94],"propose":[95],"a":[96],"new":[97],"procedure,":[100],"named":[101],"Bon-EV,":[102],"control":[104,138,236],"discovery":[106],"rate":[107],"(FDR)":[108],"based":[109],"on":[110],"Bonferroni's":[111],"approach.":[112],"RESULTS:":[113],"Simulation":[114],"studies":[115],"show":[116,199],"that":[117,200],"our":[118,180],"proposed":[119,181],"Bon-EV":[120,182,202,231,254],"also":[133],"result":[134],"better":[136],"FDR":[137,235],"samples":[147],"large":[149,227],"size(30":[150],"each":[152,159,178],"group)":[153,160],"medium":[155,225],"size":[156,173],"(15":[157],"either":[162],"independent,":[163],"somewhat":[164],"correlated,":[165],"or":[166,226],"highly":[167],"correlated":[168],"test":[169],"statistics.":[170],"When":[171],"sample":[172,228],"is":[174,258],"small":[175],"(5":[176],"group),":[179],"performance":[185],"between":[186],"Benjamini-Hochberg":[188,251],"Examples":[195],"using":[196],"RNA-Seq":[197],"while":[212],"maintaining":[213],"equivalent":[214],"power,":[215],"CONCLUSIONS:":[223],"For":[224],"sizes,":[229],"improved":[234,246],"compared":[239,248],"with":[240,249],"The":[253],"available":[259],"BonEV":[262],"package":[263],"R":[265],"download":[267],"at":[268],"https://CRAN.R-project.org/package=BonEV":[269],".":[270]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":19},{"year":2024,"cited_by_count":27},{"year":2023,"cited_by_count":23},{"year":2022,"cited_by_count":42},{"year":2021,"cited_by_count":80},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":2}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}