{"id":"https://openalex.org/W2553477268","doi":"https://doi.org/10.1186/s12859-016-1295-z","title":"DASP3: identification of protein sequences belonging to functionally relevant groups","display_name":"DASP3: identification of protein sequences belonging to functionally relevant groups","publication_year":2016,"publication_date":"2016-11-11","ids":{"openalex":"https://openalex.org/W2553477268","doi":"https://doi.org/10.1186/s12859-016-1295-z","mag":"2553477268","pmid":"https://pubmed.ncbi.nlm.nih.gov/27835946"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-016-1295-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1295-z","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1295-z","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1295-z","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046672659","display_name":"Janelle B. Leuthaeuser","orcid":"https://orcid.org/0000-0003-1942-1422"},"institutions":[{"id":"https://openalex.org/I47251452","display_name":"Wake Forest University","ror":"https://ror.org/0207ad724","country_code":"US","type":"education","lineage":["https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Janelle B. Leuthaeuser","raw_affiliation_strings":["Molecular Genetics and Genomics Program, Wake Forest University, Winston-Salem, NC, 27106, USA. jleuthae@gmail.edu","Present address: University of Richmond, Gottwald Hall C302, Richmond, VA, 23173, USA. jleuthae@gmail.edu","Molecular Genetics and Genomics Program, Wake Forest University, Winston-Salem, NC, 27106, USA"],"affiliations":[{"raw_affiliation_string":"Molecular Genetics and Genomics Program, Wake Forest University, Winston-Salem, NC, 27106, USA. jleuthae@gmail.edu","institution_ids":[]},{"raw_affiliation_string":"Present address: University of Richmond, Gottwald Hall C302, Richmond, VA, 23173, USA. jleuthae@gmail.edu","institution_ids":[]},{"raw_affiliation_string":"Molecular Genetics and Genomics Program, Wake Forest University, Winston-Salem, NC, 27106, USA","institution_ids":["https://openalex.org/I47251452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054399637","display_name":"John H. Morris","orcid":"https://orcid.org/0000-0003-0290-7979"},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John H. Morris","raw_affiliation_strings":["Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158, USA"],"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089651976","display_name":"Angela F. Harper","orcid":"https://orcid.org/0000-0002-0699-0450"},"institutions":[{"id":"https://openalex.org/I47251452","display_name":"Wake Forest University","ror":"https://ror.org/0207ad724","country_code":"US","type":"education","lineage":["https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Angela F. Harper","raw_affiliation_strings":["Department of Physics, Wake Forest University, Winston-Salem, NC, 27106, USA"],"affiliations":[{"raw_affiliation_string":"Department of Physics, Wake Forest University, Winston-Salem, NC, 27106, USA","institution_ids":["https://openalex.org/I47251452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086093811","display_name":"Thomas E. Ferrin","orcid":"https://orcid.org/0000-0001-6227-0637"},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas E. Ferrin","raw_affiliation_strings":["Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158, USA"],"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020002876","display_name":"Patricia C. Babbitt","orcid":"https://orcid.org/0000-0003-0375-9015"},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patricia C. Babbitt","raw_affiliation_strings":["Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, 94158, USA"],"affiliations":[{"raw_affiliation_string":"Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, 94158, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058687070","display_name":"Jacquelyn S. Fetrow","orcid":"https://orcid.org/0000-0002-0528-2049"},"institutions":[{"id":"https://openalex.org/I158012942","display_name":"University of Richmond","ror":"https://ror.org/03y71xh61","country_code":"US","type":"education","lineage":["https://openalex.org/I158012942"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jacquelyn S. Fetrow","raw_affiliation_strings":["Department of Chemistry, University of Richmond, Richmond, VA, 23173, USA"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Richmond, Richmond, VA, 23173, USA","institution_ids":["https://openalex.org/I158012942"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5046672659"],"corresponding_institution_ids":["https://openalex.org/I47251452"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.6972,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.75172369,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"17","issue":"1","first_page":"458","last_page":"458"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11150","display_name":"Endoplasmic Reticulum Stress and Disease","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.7458485960960388},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6470587253570557},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.6412754058837891},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5929888486862183},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5903161764144897},{"id":"https://openalex.org/keywords/evolutionary-biology","display_name":"Evolutionary biology","score":0.4679977297782898},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.34025782346725464},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.17617109417915344},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.07453832030296326}],"concepts":[{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.7458485960960388},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6470587253570557},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.6412754058837891},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5929888486862183},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5903161764144897},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.4679977297782898},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34025782346725464},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.17617109417915344},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.07453832030296326},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020134","descriptor_name":"Catalytic Domain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020134","descriptor_name":"Catalytic Domain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020134","descriptor_name":"Catalytic Domain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12859-016-1295-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1295-z","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1295-z","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:27835946","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27835946","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:escholarship.org/ark:/13030/qt60r7f4qk","is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/60r7f4qk","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC bioinformatics, vol 17, iss 1","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4073002","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5106842","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:qt60r7f4qk","is_oa":false,"landing_page_url":"http://www.escholarship.org/uc/item/60r7f4qk","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Leuthaeuser, JB; Morris, JH; Harper, AF; Ferrin, TE; Babbitt, PC; & Fetrow, JS. (2016). DASP3: identification of protein sequences belonging to functionally relevant groups. BMC BIOINFORMATICS, 17. doi: 10.1186/s12859-016-1295-z. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/60r7f4qk","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12859-016-1295-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1295-z","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1295-z","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2463924160","display_name":null,"funder_award_id":"95440","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4815039349","display_name":null,"funder_award_id":"P41-GM103311","funder_id":"https://openalex.org/F4320332622","funder_display_name":"University of California, San Francisco"},{"id":"https://openalex.org/G5056958345","display_name":null,"funder_award_id":"T32GM095440","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6962976390","display_name":null,"funder_award_id":"P41-GM103311","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G874721465","display_name":null,"funder_award_id":"GM60595","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332622","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2553477268.pdf","grobid_xml":"https://content.openalex.org/works/W2553477268.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1565276997","https://openalex.org/W1969051510","https://openalex.org/W1970710213","https://openalex.org/W1975738628","https://openalex.org/W1975914194","https://openalex.org/W1989840001","https://openalex.org/W1991254515","https://openalex.org/W1994790614","https://openalex.org/W1998490996","https://openalex.org/W2016235775","https://openalex.org/W2027542060","https://openalex.org/W2050842004","https://openalex.org/W2055043387","https://openalex.org/W2058189144","https://openalex.org/W2060797027","https://openalex.org/W2061096733","https://openalex.org/W2066227923","https://openalex.org/W2075245792","https://openalex.org/W2088411222","https://openalex.org/W2093407117","https://openalex.org/W2094713937","https://openalex.org/W2106383137","https://openalex.org/W2113561798","https://openalex.org/W2131510173","https://openalex.org/W2141006079","https://openalex.org/W2146225611","https://openalex.org/W2147526198","https://openalex.org/W2158714788","https://openalex.org/W2161072217","https://openalex.org/W2162831725","https://openalex.org/W2164461702","https://openalex.org/W2166745327","https://openalex.org/W2210228437","https://openalex.org/W4235121031","https://openalex.org/W6633829390"],"related_works":["https://openalex.org/W2898732673","https://openalex.org/W2410053581","https://openalex.org/W2383658677","https://openalex.org/W3123203398","https://openalex.org/W2415545834","https://openalex.org/W2069695727","https://openalex.org/W623104033","https://openalex.org/W1972473893","https://openalex.org/W1802639773","https://openalex.org/W2118505788"],"abstract_inverted_index":{"DASP":[0],"algorithmic":[1],"enhancements":[2,25,40],"resulted":[3],"in":[4,29,44],"improved":[5],"efficiency":[6],"and":[7,33],"accuracy":[8],"of":[9,20],"identifying":[10],"proteins":[11,61],"that":[12],"contain":[13],"active":[14],"site":[15],"features":[16],"similar":[17],"to":[18],"those":[19],"the":[21,39,55],"query":[22],"set.":[23],"These":[24],"provide":[26],"incremental":[27],"improvement":[28,43],"structure":[30],"database":[31,36],"searches":[32],"initial":[34],"sequence":[35,46],"searches;":[37],"however,":[38],"show":[41],"significant":[42],"iterative":[45,56],"searches,":[47],"suggesting":[48],"DASP3":[49],"is":[50],"an":[51],"appropriate":[52],"tool":[53],"for":[54,59],"processes":[57],"required":[58],"clustering":[60],"into":[62],"isofunctional":[63],"groups.":[64]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}