{"id":"https://openalex.org/W2551511521","doi":"https://doi.org/10.1186/s12859-016-1291-3","title":"From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration","display_name":"From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration","publication_year":2016,"publication_date":"2016-11-01","ids":{"openalex":"https://openalex.org/W2551511521","doi":"https://doi.org/10.1186/s12859-016-1291-3","mag":"2551511521","pmid":"https://pubmed.ncbi.nlm.nih.gov/28185567"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-016-1291-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1291-3","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1291-3","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1291-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"on behalf of Synergy-COPD Consortia","orcid":null},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"on behalf of Synergy-COPD Consortia","raw_affiliation_strings":["Department of Medicine, Karolinska Institutet, Unit of Computational Medicine, Stockholm, Sweden"],"affiliations":[{"raw_affiliation_string":"Department of Medicine, Karolinska Institutet, Unit of Computational Medicine, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078466508","display_name":"David G\u00f3mez-Cabrero","orcid":"https://orcid.org/0000-0003-4186-3788"},"institutions":[{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]},{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I68214267","display_name":"Regional Environmental Center for Central and Eastern Europe","ror":"https://ror.org/05b45bk66","country_code":"HU","type":"other","lineage":["https://openalex.org/I68214267"]}],"countries":["GB","HU","SE","US"],"is_corresponding":false,"raw_author_name":"David Gomez-Cabrero","raw_affiliation_strings":["Department of Medicine, Karolinska Institutet, Unit of Computational Medicine, Stockholm, 171 77, Sweden. david.gomezcabrero@ki.se","Department of Medicine, Unit of Clinical Epidemiology, Karolinska University Hospital, Solna, L8, 17176, Sweden. david.gomezcabrero@ki.se","Karolinska Institutet, Center for Molecular Medicine, Stockholm, 171 77, Sweden. david.gomezcabrero@ki.se","Mucosal and Salivary Biology Division, King's College London Dental Institute, London, UK. david.gomezcabrero@ki.se","Science for Life Laboratory, Solna, 17121, Sweden. david.gomezcabrero@ki.se","Center for Network Science, Central European University, Budapest, Hungary","Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA","Center for Complex Networks Research and Department of Physics, Northeastern University, Boston, USA"],"affiliations":[{"raw_affiliation_string":"Department of Medicine, Karolinska Institutet, Unit of Computational Medicine, Stockholm, 171 77, Sweden. david.gomezcabrero@ki.se","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Department of Medicine, Unit of Clinical Epidemiology, Karolinska University Hospital, Solna, L8, 17176, Sweden. david.gomezcabrero@ki.se","institution_ids":["https://openalex.org/I1335113835"]},{"raw_affiliation_string":"Karolinska Institutet, Center for Molecular Medicine, Stockholm, 171 77, Sweden. david.gomezcabrero@ki.se","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Mucosal and Salivary Biology Division, King's College London Dental Institute, London, UK. david.gomezcabrero@ki.se","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Science for Life Laboratory, Solna, 17121, Sweden. david.gomezcabrero@ki.se","institution_ids":["https://openalex.org/I2800139495"]},{"raw_affiliation_string":"Center for Network Science, Central European University, Budapest, Hungary","institution_ids":["https://openalex.org/I68214267"]},{"raw_affiliation_string":"Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA","institution_ids":["https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Center for Complex Networks Research and Department of Physics, Northeastern University, Boston, USA","institution_ids":["https://openalex.org/I12912129"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025090907","display_name":"J\u00f6rg Menche","orcid":"https://orcid.org/0000-0002-1583-6404"},"institutions":[{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I68214267","display_name":"Regional Environmental Center for Central and Eastern Europe","ror":"https://ror.org/05b45bk66","country_code":"HU","type":"other","lineage":["https://openalex.org/I68214267"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES","HU","US"],"is_corresponding":false,"raw_author_name":"J\u00f6rg Menche","raw_affiliation_strings":["Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA","Center for Complex Networks Research and Department of Physics, Northeastern University, Boston, MA, USA","Center for Network Science, Central European University, Budapest, Hungary","Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Center for Complex Networks Research and Department of Physics, Northeastern University, Boston, MA, USA","institution_ids":["https://openalex.org/I12912129"]},{"raw_affiliation_string":"Center for Network Science, Central European University, Budapest, Hungary","institution_ids":["https://openalex.org/I68214267"]},{"raw_affiliation_string":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127","https://openalex.org/I4210115097","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082917419","display_name":"Claudia Vargas","orcid":null},"institutions":[{"id":"https://openalex.org/I4210111366","display_name":"Centre for Biomedical Network Research on Rare Diseases","ror":"https://ror.org/01ygm5w19","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210111366"]},{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Claudia Vargas","raw_affiliation_strings":["Center for Biomedical Network Research in Respiratory Diseases (CIBERES), Madrid, Spain","Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain","Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Center for Biomedical Network Research in Respiratory Diseases (CIBERES), Madrid, Spain","institution_ids":["https://openalex.org/I4210111366"]},{"raw_affiliation_string":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127","https://openalex.org/I4210115097","https://openalex.org/I4210160192"]},{"raw_affiliation_string":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127","https://openalex.org/I4210115097","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051157475","display_name":"Isaac Cano","orcid":"https://orcid.org/0000-0003-2938-7459"},"institutions":[{"id":"https://openalex.org/I105862471","display_name":"Biomax Informatics (Germany)","ror":"https://ror.org/02h1y5y54","country_code":"DE","type":"company","lineage":["https://openalex.org/I105862471"]},{"id":"https://openalex.org/I4210111366","display_name":"Centre for Biomedical Network Research on Rare Diseases","ror":"https://ror.org/01ygm5w19","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210111366"]},{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["DE","ES"],"is_corresponding":false,"raw_author_name":"Isaac Cano","raw_affiliation_strings":["Center for Biomedical Network Research in Respiratory Diseases (CIBERES), Madrid, Spain","Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain","Biomax Informatics AG , Planegg, Germany"],"affiliations":[{"raw_affiliation_string":"Center for Biomedical Network Research in Respiratory Diseases (CIBERES), Madrid, Spain","institution_ids":["https://openalex.org/I4210111366"]},{"raw_affiliation_string":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127","https://openalex.org/I4210115097","https://openalex.org/I4210160192"]},{"raw_affiliation_string":"Biomax Informatics AG , Planegg, Germany","institution_ids":["https://openalex.org/I105862471"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105844329","display_name":"Dieter Maier","orcid":null},"institutions":[{"id":"https://openalex.org/I105862471","display_name":"Biomax Informatics (Germany)","ror":"https://ror.org/02h1y5y54","country_code":"DE","type":"company","lineage":["https://openalex.org/I105862471"]},{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Dieter Maier","raw_affiliation_strings":["Biomax Informatics AG, Planegg, Germany","Center for Complex Networks Research and Department of Physics, Northeastern University, Boston, USA"],"affiliations":[{"raw_affiliation_string":"Biomax Informatics AG, Planegg, Germany","institution_ids":["https://openalex.org/I105862471"]},{"raw_affiliation_string":"Center for Complex Networks Research and Department of Physics, Northeastern University, Boston, USA","institution_ids":["https://openalex.org/I12912129"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038976962","display_name":"Albert-\u0139aszl\u00f3 Barab\u00e1si","orcid":"https://orcid.org/0000-0002-4028-3522"},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I68214267","display_name":"Regional Environmental Center for Central and Eastern Europe","ror":"https://ror.org/05b45bk66","country_code":"HU","type":"other","lineage":["https://openalex.org/I68214267"]}],"countries":["HU","SE","US"],"is_corresponding":false,"raw_author_name":"Albert-L\u00e1szl\u00f3 Barab\u00e1si","raw_affiliation_strings":["Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA","Center for Complex Networks Research and Department of Physics, Northeastern University, Boston, MA, USA","Center for Network Science, Central European University, Budapest, Hungary","Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA","Department of Medicine, Karolinska Institutet, Unit of Computational Medicine, Stockholm, Sweden"],"affiliations":[{"raw_affiliation_string":"Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Center for Complex Networks Research and Department of Physics, Northeastern University, Boston, MA, USA","institution_ids":["https://openalex.org/I12912129"]},{"raw_affiliation_string":"Center for Network Science, Central European University, Budapest, Hungary","institution_ids":["https://openalex.org/I68214267"]},{"raw_affiliation_string":"Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Medicine, Karolinska Institutet, Unit of Computational Medicine, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035252549","display_name":"Jesper Tegn\u00e9r","orcid":"https://orcid.org/0000-0002-9568-5588"},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]},{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES","SE"],"is_corresponding":false,"raw_author_name":"Jesper Tegn\u00e9r","raw_affiliation_strings":["Department of Medicine, Karolinska Institutet, Unit of Computational Medicine, Stockholm, 171 77, Sweden","Department of Medicine, Unit of Clinical Epidemiology, Karolinska University Hospital, Solna, L8, 17176, Sweden","Karolinska Institutet, Center for Molecular Medicine, Stockholm, 171 77, Sweden","Science for Life Laboratory, Solna, 17121, Sweden","Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Department of Medicine, Karolinska Institutet, Unit of Computational Medicine, Stockholm, 171 77, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Department of Medicine, Unit of Clinical Epidemiology, Karolinska University Hospital, Solna, L8, 17176, Sweden","institution_ids":["https://openalex.org/I1335113835"]},{"raw_affiliation_string":"Karolinska Institutet, Center for Molecular Medicine, Stockholm, 171 77, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Science for Life Laboratory, Solna, 17121, Sweden","institution_ids":["https://openalex.org/I2800139495"]},{"raw_affiliation_string":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127","https://openalex.org/I4210115097","https://openalex.org/I4210160192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042593224","display_name":"Josep Roca","orcid":"https://orcid.org/0000-0003-4768-8722"},"institutions":[{"id":"https://openalex.org/I4210111366","display_name":"Centre for Biomedical Network Research on Rare Diseases","ror":"https://ror.org/01ygm5w19","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210111366"]},{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210158267","display_name":"Fundaci\u00f3 Cl\u00ednic per a la Recerca Biom\u00e8dica","ror":"https://ror.org/03mw46n78","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210158267","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210163440","display_name":"Medical Research Network","ror":"https://ror.org/05e56c835","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210163440"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES","US"],"is_corresponding":false,"raw_author_name":"Josep Roca","raw_affiliation_strings":["Center for Biomedical Network Research in Respiratory Diseases (CIBERES), Madrid, Spain. jroca@clinic.ub.es","Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain. jroca@clinic.ub.es"],"affiliations":[{"raw_affiliation_string":"Center for Biomedical Network Research in Respiratory Diseases (CIBERES), Madrid, Spain. jroca@clinic.ub.es","institution_ids":["https://openalex.org/I4210163440","https://openalex.org/I4210111366"]},{"raw_affiliation_string":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain. jroca@clinic.ub.es","institution_ids":["https://openalex.org/I4210160192","https://openalex.org/I71999127","https://openalex.org/I4210158267","https://openalex.org/I4210115097"]}]}],"institutions":[],"countries_distinct_count":6,"institutions_distinct_count":9,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I28166907"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":3.3377,"has_fulltext":true,"cited_by_count":23,"citation_normalized_percentile":{"value":0.92605438,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"17","issue":"S15","first_page":"441","last_page":"441"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12246","display_name":"Chronic Disease Management Strategies","score":0.980400025844574,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9466000199317932,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/comorbidity","display_name":"Comorbidity","score":0.8792904019355774},{"id":"https://openalex.org/keywords/copd","display_name":"COPD","score":0.6581814885139465},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.61090487241745},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.46153414249420166},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.44644004106521606},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.4318038821220398},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3817373514175415},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.33823317289352417},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.28254908323287964},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.23722875118255615},{"id":"https://openalex.org/keywords/psychiatry","display_name":"Psychiatry","score":0.15221241116523743},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.12457874417304993}],"concepts":[{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.8792904019355774},{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.6581814885139465},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.61090487241745},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46153414249420166},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.44644004106521606},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.4318038821220398},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3817373514175415},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.33823317289352417},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.28254908323287964},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23722875118255615},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.15221241116523743},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12457874417304993},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008019","descriptor_name":"Life Style","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008019","descriptor_name":"Life Style","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008019","descriptor_name":"Life Style","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1186/s12859-016-1291-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1291-3","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1291-3","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:28185567","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28185567","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:recercat.cat:2072/284352","is_oa":true,"landing_page_url":"http://hdl.handle.net/2445/110568","pdf_url":null,"source":{"id":"https://openalex.org/S4306402147","display_name":"RECERCAT (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:dash.harvard.edu:1/29739013","is_oa":true,"landing_page_url":"http://nrs.harvard.edu/urn-3:HUL.InstRepos:29739013","pdf_url":null,"source":{"id":"https://openalex.org/S4306401540","display_name":"Digital Access to Scholarship at Harvard (DASH) (Harvard University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I136199984","host_organization_name":"Harvard University","host_organization_lineage":["https://openalex.org/I136199984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:dce5ba5968954e4b9849f9bf37ec18de","is_oa":true,"landing_page_url":"https://doaj.org/article/dce5ba5968954e4b9849f9bf37ec18de","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 17, Iss S15, Pp 23-35 (2016)","raw_type":"article"},{"id":"pmh:oai:https://openresearch.ceu.edu:20.500.14018/28573","is_oa":true,"landing_page_url":"https://hdl.handle.net/20.500.14018/28573","pdf_url":null,"source":{"id":"https://openalex.org/S4306401981","display_name":"Open Research (Auckland University of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I39854758","host_organization_name":"Auckland University of Technology","host_organization_lineage":["https://openalex.org/I39854758"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"17","raw_type":"Journal article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5133493","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5133493","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"doi:10.6084/m9.figshare.c.3634505.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.c.3634505.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12859-016-1291-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1291-3","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1291-3","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.800000011920929,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2551511521.pdf","grobid_xml":"https://content.openalex.org/works/W2551511521.grobid-xml"},"referenced_works_count":96,"referenced_works":["https://openalex.org/W103686129","https://openalex.org/W775956452","https://openalex.org/W900681215","https://openalex.org/W1490161904","https://openalex.org/W1492846462","https://openalex.org/W1504676147","https://openalex.org/W1541834598","https://openalex.org/W1543134559","https://openalex.org/W1548738226","https://openalex.org/W1550706719","https://openalex.org/W1859222707","https://openalex.org/W1912936344","https://openalex.org/W1921210167","https://openalex.org/W1951307256","https://openalex.org/W1952826802","https://openalex.org/W1968363067","https://openalex.org/W1970809722","https://openalex.org/W1973597670","https://openalex.org/W1975840606","https://openalex.org/W1984350698","https://openalex.org/W1985293429","https://openalex.org/W1986657538","https://openalex.org/W1990458686","https://openalex.org/W2002099441","https://openalex.org/W2006196877","https://openalex.org/W2010422325","https://openalex.org/W2021835206","https://openalex.org/W2022888213","https://openalex.org/W2031950862","https://openalex.org/W2036445364","https://openalex.org/W2045886232","https://openalex.org/W2049292276","https://openalex.org/W2050136856","https://openalex.org/W2051674484","https://openalex.org/W2056782561","https://openalex.org/W2056795330","https://openalex.org/W2057304386","https://openalex.org/W2065500018","https://openalex.org/W2068234084","https://openalex.org/W2077523026","https://openalex.org/W2079474654","https://openalex.org/W2081375228","https://openalex.org/W2081623685","https://openalex.org/W2083045667","https://openalex.org/W2094791001","https://openalex.org/W2095845810","https://openalex.org/W2098065746","https://openalex.org/W2103017472","https://openalex.org/W2106280897","https://openalex.org/W2107398008","https://openalex.org/W2107580398","https://openalex.org/W2107952444","https://openalex.org/W2110065044","https://openalex.org/W2111897974","https://openalex.org/W2113953831","https://openalex.org/W2115771202","https://openalex.org/W2117678288","https://openalex.org/W2118106787","https://openalex.org/W2120847175","https://openalex.org/W2123848794","https://openalex.org/W2124001239","https://openalex.org/W2125065061","https://openalex.org/W2130410032","https://openalex.org/W2137200212","https://openalex.org/W2137828617","https://openalex.org/W2138958247","https://openalex.org/W2139898172","https://openalex.org/W2144652900","https://openalex.org/W2144999669","https://openalex.org/W2150445188","https://openalex.org/W2152274187","https://openalex.org/W2152415104","https://openalex.org/W2154438420","https://openalex.org/W2154583077","https://openalex.org/W2156046391","https://openalex.org/W2157251004","https://openalex.org/W2159401492","https://openalex.org/W2161363224","https://openalex.org/W2162151166","https://openalex.org/W2166097870","https://openalex.org/W2166298321","https://openalex.org/W2228064650","https://openalex.org/W2253043407","https://openalex.org/W2327355331","https://openalex.org/W2400343779","https://openalex.org/W2401521228","https://openalex.org/W2413292342","https://openalex.org/W2416627559","https://openalex.org/W2460445187","https://openalex.org/W2740155436","https://openalex.org/W2995395573","https://openalex.org/W4210958280","https://openalex.org/W4213060373","https://openalex.org/W4253765510","https://openalex.org/W4301238139","https://openalex.org/W7026658942"],"related_works":["https://openalex.org/W3146691973","https://openalex.org/W3142286882","https://openalex.org/W4245372082","https://openalex.org/W3215586121","https://openalex.org/W1978188354","https://openalex.org/W3141224953","https://openalex.org/W2252383104","https://openalex.org/W2765738011","https://openalex.org/W2254851461","https://openalex.org/W2155091457"],"abstract_inverted_index":{"The":[0,14],"developed":[1],"framework":[2],"provides":[3],"novel":[4],"insights":[5],"in":[6],"COPD":[7,10],"and":[8,21,30],"especially":[9],"co-morbidity":[11,37],"associated":[12],"mechanisms.":[13],"methodology":[15],"could":[16],"be":[17],"used":[18],"to":[19],"discover":[20],"decipher":[22],"the":[23,33],"molecular":[24],"underpinning":[25],"of":[26,35],"other":[27],"comorbidity":[28],"relationships":[29],"furthermore,":[31],"allow":[32],"identification":[34],"candidate":[36],"biomarkers.":[38]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":3}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2016-11-30T00:00:00"}