{"id":"https://openalex.org/W2465909412","doi":"https://doi.org/10.1186/s12859-016-1111-9","title":"multiDE: a dimension reduced model based statistical method for differential expression analysis using RNA-sequencing data with multiple treatment conditions","display_name":"multiDE: a dimension reduced model based statistical method for differential expression analysis using RNA-sequencing data with multiple treatment conditions","publication_year":2016,"publication_date":"2016-06-22","ids":{"openalex":"https://openalex.org/W2465909412","doi":"https://doi.org/10.1186/s12859-016-1111-9","mag":"2465909412","pmid":"https://pubmed.ncbi.nlm.nih.gov/27334001"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-016-1111-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1111-9","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1111-9","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1111-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071299854","display_name":"Guangliang Kang","orcid":null},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guangliang Kang","raw_affiliation_strings":["Institute of Biostatistics, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai, 200438, People's Republic of China","Institute of Biostatistics, School of Life Sciences, Fudan University, Shanghai, People\u2019s Republic of China"],"affiliations":[{"raw_affiliation_string":"Institute of Biostatistics, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai, 200438, People's Republic of China","institution_ids":[]},{"raw_affiliation_string":"Institute of Biostatistics, School of Life Sciences, Fudan University, Shanghai, People\u2019s Republic of China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101618629","display_name":"Li Du","orcid":"https://orcid.org/0000-0001-5807-3585"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Du","raw_affiliation_strings":["Institute of Biostatistics, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai, 200438, People's Republic of China","Institute of Biostatistics, School of Life Sciences, Fudan University, Shanghai, People\u2019s Republic of China"],"affiliations":[{"raw_affiliation_string":"Institute of Biostatistics, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai, 200438, People's Republic of China","institution_ids":[]},{"raw_affiliation_string":"Institute of Biostatistics, School of Life Sciences, Fudan University, Shanghai, People\u2019s Republic of China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070944178","display_name":"Hong Zhang","orcid":"https://orcid.org/0000-0002-6490-0249"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4391768242","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866","country_code":null,"type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hong Zhang","raw_affiliation_strings":["Institute of Biostatistics, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai, 200438, People's Republic of China. zhanghfd@fudan.edu.cn","State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai, 200438, People's Republic of China. zhanghfd@fudan.edu.cn","Institute of Biostatistics, School of Life Sciences, Fudan University, Shanghai, People\u2019s Republic of China","State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, People\u2019s Republic of China"],"affiliations":[{"raw_affiliation_string":"Institute of Biostatistics, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai, 200438, People's Republic of China. zhanghfd@fudan.edu.cn","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai, 200438, People's Republic of China. zhanghfd@fudan.edu.cn","institution_ids":[]},{"raw_affiliation_string":"Institute of Biostatistics, School of Life Sciences, Fudan University, Shanghai, People\u2019s Republic of China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, People\u2019s Republic of China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5070944178"],"corresponding_institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4391768242"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.3486,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.68668242,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"17","issue":"1","first_page":"248","last_page":"248"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.682160496711731},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5629122257232666},{"id":"https://openalex.org/keywords/dimension","display_name":"Dimension (graph theory)","score":0.5492423176765442},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.46583858132362366},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.46430447697639465},{"id":"https://openalex.org/keywords/statistical-analysis","display_name":"Statistical analysis","score":0.4619373083114624},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.43548229336738586},{"id":"https://openalex.org/keywords/differential","display_name":"Differential (mechanical device)","score":0.42127883434295654},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.41458773612976074},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3731369376182556},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3586083650588989},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.24883496761322021},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2402251660823822},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.21081343293190002},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.20822107791900635},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08563315868377686}],"concepts":[{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.682160496711731},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5629122257232666},{"id":"https://openalex.org/C33676613","wikidata":"https://www.wikidata.org/wiki/Q13415176","display_name":"Dimension (graph theory)","level":2,"score":0.5492423176765442},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.46583858132362366},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.46430447697639465},{"id":"https://openalex.org/C2986587452","wikidata":"https://www.wikidata.org/wiki/Q938438","display_name":"Statistical analysis","level":2,"score":0.4619373083114624},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43548229336738586},{"id":"https://openalex.org/C93226319","wikidata":"https://www.wikidata.org/wiki/Q193137","display_name":"Differential (mechanical device)","level":2,"score":0.42127883434295654},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.41458773612976074},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3731369376182556},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3586083650588989},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24883496761322021},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2402251660823822},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21081343293190002},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.20822107791900635},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08563315868377686},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011565","descriptor_name":"Psoriasis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D011565","descriptor_name":"Psoriasis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D011565","descriptor_name":"Psoriasis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D011565","descriptor_name":"Psoriasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011565","descriptor_name":"Psoriasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011565","descriptor_name":"Psoriasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053595","descriptor_name":"Embryonic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053595","descriptor_name":"Embryonic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053595","descriptor_name":"Embryonic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1186/s12859-016-1111-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1111-9","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1111-9","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:27334001","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27334001","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:4917940","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4917940","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-016-1111-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-1111-9","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-1111-9","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions","score":0.7400000095367432}],"awards":[{"id":"https://openalex.org/G1121271761","display_name":null,"funder_award_id":"Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6380256900","display_name":null,"funder_award_id":"11371101","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2465909412.pdf","grobid_xml":"https://content.openalex.org/works/W2465909412.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1519258930","https://openalex.org/W1911601650","https://openalex.org/W1968813912","https://openalex.org/W1975285668","https://openalex.org/W1977558417","https://openalex.org/W1986161286","https://openalex.org/W1998530321","https://openalex.org/W2007439698","https://openalex.org/W2040177546","https://openalex.org/W2043586699","https://openalex.org/W2044702943","https://openalex.org/W2045388302","https://openalex.org/W2049380243","https://openalex.org/W2064045348","https://openalex.org/W2075408374","https://openalex.org/W2097065948","https://openalex.org/W2102607537","https://openalex.org/W2106319366","https://openalex.org/W2107018762","https://openalex.org/W2114104545","https://openalex.org/W2114405789","https://openalex.org/W2119034410","https://openalex.org/W2119185338","https://openalex.org/W2130880175","https://openalex.org/W2132893003","https://openalex.org/W2133465414","https://openalex.org/W2134526812","https://openalex.org/W2141458291","https://openalex.org/W2142165994","https://openalex.org/W2152239989","https://openalex.org/W2154431984","https://openalex.org/W2156631105","https://openalex.org/W2158217645","https://openalex.org/W2168342464"],"related_works":["https://openalex.org/W2392243736","https://openalex.org/W86652014","https://openalex.org/W1987895267","https://openalex.org/W2328518092","https://openalex.org/W3101249758","https://openalex.org/W2382079200","https://openalex.org/W2350519135","https://openalex.org/W2415545834","https://openalex.org/W2069695727","https://openalex.org/W2066759926"],"abstract_inverted_index":{"When":[0,14],"the":[1,11,15,25],"number":[2,16],"of":[3,17],"conditions":[4,18],"is":[5,19],"two,":[6,22],"multiDE":[7,23],"performs":[8],"comparably":[9],"with":[10],"benchmark":[12,26],"methods.":[13,27],"greater":[20],"than":[21],"outperforms":[24]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-04-16T08:26:57.006410","created_date":"2025-10-10T00:00:00"}