{"id":"https://openalex.org/W2238930303","doi":"https://doi.org/10.1186/s12859-016-0881-4","title":"PTESFinder: a computational method to identify post-transcriptional exon shuffling (PTES) events","display_name":"PTESFinder: a computational method to identify post-transcriptional exon shuffling (PTES) events","publication_year":2016,"publication_date":"2016-01-13","ids":{"openalex":"https://openalex.org/W2238930303","doi":"https://doi.org/10.1186/s12859-016-0881-4","mag":"2238930303","pmid":"https://pubmed.ncbi.nlm.nih.gov/26758031"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-016-0881-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-0881-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-0881-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-0881-4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020582052","display_name":"Osagie Izuogu","orcid":"https://orcid.org/0000-0003-3116-2558"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Osagie G. Izuogu","raw_affiliation_strings":["Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK. g.izuogu@ncl.ac.uk","Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK"],"raw_orcid":"https://orcid.org/0000-0003-3116-2558","affiliations":[{"raw_affiliation_string":"Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK. g.izuogu@ncl.ac.uk","institution_ids":["https://openalex.org/I84884186"]},{"raw_affiliation_string":"Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055776822","display_name":"Abd Alhasan","orcid":null},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Abd A. Alhasan","raw_affiliation_strings":["Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK. abd.al-hasan@newcastle.ac.uk","Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK. abd.al-hasan@newcastle.ac.uk","institution_ids":["https://openalex.org/I84884186"]},{"raw_affiliation_string":"Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069561480","display_name":"Hani Al-Afghani","orcid":"https://orcid.org/0000-0001-9307-2860"},"institutions":[{"id":"https://openalex.org/I4210130698","display_name":"Security Forces Hospital","ror":"https://ror.org/035n3nf68","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210130698"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Hani M. Alafghani","raw_affiliation_strings":["Security Forces Hostpital, P. O. Box 2748-24268-8541, Makkah, Kingdom of Saudi Arabia. hani940@hotmail.com","Security Forces Hostpital, P. O. Box 2748-24268-8541, Makkah, Kingdom of Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Security Forces Hostpital, P. O. Box 2748-24268-8541, Makkah, Kingdom of Saudi Arabia. hani940@hotmail.com","institution_ids":["https://openalex.org/I4210130698"]},{"raw_affiliation_string":"Security Forces Hostpital, P. O. Box 2748-24268-8541, Makkah, Kingdom of Saudi Arabia","institution_ids":["https://openalex.org/I4210130698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060121649","display_name":"Mauro Santibanez\u2010Koref","orcid":"https://orcid.org/0000-0002-8749-9398"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mauro Santibanez-Koref","raw_affiliation_strings":["Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK. mauro.santibanez-koref@ncl.ac.uk","Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK. mauro.santibanez-koref@ncl.ac.uk","institution_ids":["https://openalex.org/I84884186"]},{"raw_affiliation_string":"Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044531974","display_name":"David J. Elliott","orcid":"https://orcid.org/0000-0002-6930-0699"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David J. Elliott","raw_affiliation_strings":["Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024984441","display_name":"Michael S. Jackson","orcid":"https://orcid.org/0000-0001-7179-1354"},"institutions":[{"id":"https://openalex.org/I2800844553","display_name":"Newcastle College","ror":"https://ror.org/04jmcwc90","country_code":"GB","type":"education","lineage":["https://openalex.org/I2800844553"]},{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michael S. Jackson","raw_affiliation_strings":["Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK. michael.jackson@ncl.ac.uk","Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK. michael.jackson@ncl.ac.uk","institution_ids":["https://openalex.org/I84884186","https://openalex.org/I2800844553"]},{"raw_affiliation_string":"Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5020582052"],"corresponding_institution_ids":["https://openalex.org/I84884186"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":2245,"currency":"EUR","value_usd":2421},"fwci":3.6556,"has_fulltext":true,"cited_by_count":68,"citation_normalized_percentile":{"value":0.93015187,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"17","issue":"1","first_page":"31","last_page":"31"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.2904999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.2904999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.19900000095367432,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.1324000060558319,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/shuffling","display_name":"Shuffling","score":0.7925912141799927},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.625299334526062},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.5946691632270813},{"id":"https://openalex.org/keywords/exon","display_name":"Exon","score":0.5898268818855286},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.48619669675827026},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.450114369392395},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.33292412757873535},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3308566212654114},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.19275355339050293},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.10312026739120483},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.07717001438140869}],"concepts":[{"id":"https://openalex.org/C167927819","wikidata":"https://www.wikidata.org/wiki/Q1930567","display_name":"Shuffling","level":2,"score":0.7925912141799927},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.625299334526062},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.5946691632270813},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.5898268818855286},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.48619669675827026},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.450114369392395},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.33292412757873535},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3308566212654114},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19275355339050293},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.10312026739120483},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.07717001438140869}],"mesh":[{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-016-0881-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-0881-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-0881-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:26758031","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26758031","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:eprint.ncl.ac.uk:218408","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306402485","display_name":"Newcastle University ePrints (Newcastle Univesity)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I84884186","host_organization_name":"Newcastle University","host_organization_lineage":["https://openalex.org/I84884186"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""},{"id":"pmh:oai:europepmc.org:3685898","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4711006","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-016-0881-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-016-0881-4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-016-0881-4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1876424206","display_name":null,"funder_award_id":"WT089225MA","funder_id":"https://openalex.org/F4320307874","funder_display_name":"Wellcome"},{"id":"https://openalex.org/G5569190791","display_name":null,"funder_award_id":"RPG-2012-795","funder_id":"https://openalex.org/F4320319993","funder_display_name":"Leverhulme Trust"},{"id":"https://openalex.org/G7949455086","display_name":"BB/J014516/1","funder_award_id":"BB/J014516/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320307874","display_name":"Wellcome","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320319993","display_name":"Leverhulme Trust","ror":"https://ror.org/012mzw131"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2238930303.pdf","grobid_xml":"https://content.openalex.org/works/W2238930303.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1521279639","https://openalex.org/W1972146321","https://openalex.org/W1973235001","https://openalex.org/W1975909559","https://openalex.org/W1981528949","https://openalex.org/W1991082489","https://openalex.org/W2017507204","https://openalex.org/W2017919052","https://openalex.org/W2023139734","https://openalex.org/W2034305079","https://openalex.org/W2034587103","https://openalex.org/W2051477788","https://openalex.org/W2051615060","https://openalex.org/W2054891772","https://openalex.org/W2055185462","https://openalex.org/W2055493067","https://openalex.org/W2058835062","https://openalex.org/W2063370830","https://openalex.org/W2064165694","https://openalex.org/W2064593184","https://openalex.org/W2068540264","https://openalex.org/W2086055453","https://openalex.org/W2088128227","https://openalex.org/W2092977521","https://openalex.org/W2102610257","https://openalex.org/W2102619694","https://openalex.org/W2108234281","https://openalex.org/W2115662330","https://openalex.org/W2117608012","https://openalex.org/W2118723944","https://openalex.org/W2122340645","https://openalex.org/W2124985265","https://openalex.org/W2126144698","https://openalex.org/W2126938291","https://openalex.org/W2128016314","https://openalex.org/W2132340288","https://openalex.org/W2136145671","https://openalex.org/W2139399606","https://openalex.org/W2144283851","https://openalex.org/W2147625377","https://openalex.org/W2147806662","https://openalex.org/W2149574104","https://openalex.org/W2152719653","https://openalex.org/W2157160484","https://openalex.org/W2161028234","https://openalex.org/W2161361792","https://openalex.org/W2169456326","https://openalex.org/W2170551349","https://openalex.org/W4293196852"],"related_works":["https://openalex.org/W4213239787","https://openalex.org/W4377131110","https://openalex.org/W2045745654","https://openalex.org/W2114337652","https://openalex.org/W4388857216","https://openalex.org/W2046590706","https://openalex.org/W4390419005","https://openalex.org/W2949444602","https://openalex.org/W1587991081","https://openalex.org/W2386184744"],"abstract_inverted_index":{"BACKGROUND:":[0],"Transcripts,":[1],"which":[2],"have":[3,11,22,56],"been":[4,23,57],"subject":[5],"to":[6,41,59,75,91,123,158,164,187],"Post-transcriptional":[7],"exon":[8,13,120],"shuffling":[9],"(PTES),":[10],"an":[12],"order":[14],"inconsistent":[15],"with":[16,129],"the":[17,196],"underlying":[18],"genomic":[19],"sequence.":[20],"These":[21],"identified":[24],"in":[25,62],"a":[26,78,87,141],"wide":[27,79],"variety":[28,80,142],"of":[29,67,81,143,181,190,200],"tissues":[30],"and":[31,37,46,111,114,118,137,152,173,184,198],"cell":[32],"types":[33],"from":[34,77,95,107],"many":[35],"eukaryotes,":[36],"are":[38],"now":[39],"known":[40,179],"be":[42,60,72],"mostly":[43],"circular,":[44],"cytoplasmic,":[45],"non-coding.":[47],"Although":[48],"there":[49],"is":[50],"no":[51],"uniformly":[52],"ascribed":[53],"function,":[54],"several":[55],"shown":[58],"involved":[61],"gene":[63],"regulation.":[64],"Accurate":[65],"identification":[66],"these":[68,93,201],"transcripts":[69,94],"can,":[70],"however,":[71],"difficult":[73],"due":[74],"artefacts":[76,105],"sources.":[82],"RESULTS:":[83],"Here,":[84],"we":[85],"present":[86],"computational":[88],"method,":[89],"PTESFinder,":[90],"identify":[92,165],"high":[96,171],"throughput":[97],"RNAseq":[98],"data.":[99],"Uniquely,":[100],"it":[101],"systematically":[102],"excludes":[103],"potential":[104],"emanating":[106],"pseudogenes,":[108],"segmental":[109],"duplications,":[110],"template":[112],"switching,":[113],"outputs":[115],"both":[116],"PTES":[117],"canonical":[119],"junction":[121],"counts":[122],"facilitate":[124,188,195],"comparative":[125],"analyses.":[126],"In":[127],"comparison":[128,189],"four":[130],"existing":[131],"methods,":[132],"PTESFinder":[133,146,193],"achieves":[134],"highest":[135],"specificity":[136],"comparable":[138],"sensitivity":[139,172],"at":[140],"read":[144],"depths.":[145],"also":[147],"identifies":[148],"between":[149],"13":[150],"%":[151,154],"41.6":[153],"more":[155],"structures,":[156],"compared":[157],"publicly":[159],"available":[160],"methods":[161],"recently":[162],"used":[163],"human":[166],"circular":[167],"RNAs.":[168],"CONCLUSIONS:":[169],"With":[170],"specificity,":[174],"user-adjustable":[175],"filters":[176],"that":[177],"target":[178],"sources":[180],"false":[182],"positives,":[183],"tailored":[185],"output":[186],"transcript":[191],"levels,":[192],"will":[194],"discovery":[197],"analysis":[199],"poorly":[202],"understood":[203],"transcripts.":[204]},"counts_by_year":[{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}