{"id":"https://openalex.org/W2062075449","doi":"https://doi.org/10.1186/s12859-014-0415-x","title":"Interactive visual exploration of overlapping similar structures for three-dimensional microscope images","display_name":"Interactive visual exploration of overlapping similar structures for three-dimensional microscope images","publication_year":2014,"publication_date":"2014-12-01","ids":{"openalex":"https://openalex.org/W2062075449","doi":"https://doi.org/10.1186/s12859-014-0415-x","mag":"2062075449","pmid":"https://pubmed.ncbi.nlm.nih.gov/25523409"},"language":"en","primary_location":{"id":"doi:10.1186/s12859-014-0415-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-014-0415-x","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-014-0415-x","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-014-0415-x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076496418","display_name":"Megumi Nakao","orcid":"https://orcid.org/0000-0002-5508-4366"},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Megumi Nakao","raw_affiliation_strings":["Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan. megumi@i.kyoto-u.ac.jp","Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan. megumi@i.kyoto-u.ac.jp","institution_ids":[]},{"raw_affiliation_string":"Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081907628","display_name":"Shintaro Takemoto","orcid":null},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shintaro Takemoto","raw_affiliation_strings":["Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan. takemoto@sys.i.kyoto-u.ac.jp","Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan. takemoto@sys.i.kyoto-u.ac.jp","institution_ids":[]},{"raw_affiliation_string":"Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100840635","display_name":"Tadao Sugiura","orcid":null},"institutions":[{"id":"https://openalex.org/I75917431","display_name":"Nara Institute of Science and Technology","ror":"https://ror.org/05bhada84","country_code":"JP","type":"education","lineage":["https://openalex.org/I75917431"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tadao Sugiura","raw_affiliation_strings":["Graduate School of Information Science, Nara Institute of Science and Technology, 8916-5, Takayama, Ikoma, Nara, Japan. sugiura@is.naist.jp","Graduate School of Information Science, Nara Institute of Science and Technology, 8916-5, Takayama, Ikoma, Nara, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Information Science, Nara Institute of Science and Technology, 8916-5, Takayama, Ikoma, Nara, Japan. sugiura@is.naist.jp","institution_ids":[]},{"raw_affiliation_string":"Graduate School of Information Science, Nara Institute of Science and Technology, 8916-5, Takayama, Ikoma, Nara, Japan","institution_ids":["https://openalex.org/I75917431"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103076662","display_name":"Kazuaki Sawada","orcid":"https://orcid.org/0000-0002-7410-6604"},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuaki Sawada","raw_affiliation_strings":["Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan. sawady@ec.hokudai.ac.jp","Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan. sawady@ec.hokudai.ac.jp","institution_ids":[]},{"raw_affiliation_string":"Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113983606","display_name":"Ryosuke Kawakami","orcid":null},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryosuke Kawakami","raw_affiliation_strings":["Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan. rkawascb@es.hokudai.ac.jp","Research Institute for Electronic Science, Hokkaido University, Sapporo, Japan. rkawascb@es.hokudai.ac.jp","Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan. rkawascb@es.hokudai.ac.jp","institution_ids":[]},{"raw_affiliation_string":"Research Institute for Electronic Science, Hokkaido University, Sapporo, Japan. rkawascb@es.hokudai.ac.jp","institution_ids":[]},{"raw_affiliation_string":"Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055208450","display_name":"Tomomi Nemoto","orcid":"https://orcid.org/0000-0001-6102-1495"},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomomi Nemoto","raw_affiliation_strings":["Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan. tn@es.hokudai.ac.jp","Research Institute for Electronic Science, Hokkaido University, Sapporo, Japan. tn@es.hokudai.ac.jp","Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan. tn@es.hokudai.ac.jp","institution_ids":[]},{"raw_affiliation_string":"Research Institute for Electronic Science, Hokkaido University, Sapporo, Japan. tn@es.hokudai.ac.jp","institution_ids":[]},{"raw_affiliation_string":"Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089800489","display_name":"Tetsuya Matsuda","orcid":"https://orcid.org/0000-0002-2339-1521"},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tetsuya Matsuda","raw_affiliation_strings":["Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan. tetsu@i.kyoto-u.ac.jp","Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan. tetsu@i.kyoto-u.ac.jp","institution_ids":[]},{"raw_affiliation_string":"Graduate School of Informatics, Kyoto University, Yoshida Honmachi, Sakyo, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5076496418"],"corresponding_institution_ids":["https://openalex.org/I22299242"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.05462932,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"15","issue":"1","first_page":"415","last_page":"415"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.3682999908924103,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.3682999908924103,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.22390000522136688,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12923","display_name":"Digital Image Processing Techniques","score":0.08489999920129776,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.7824304103851318},{"id":"https://openalex.org/keywords/volume-rendering","display_name":"Volume rendering","score":0.7645741701126099},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7243450284004211},{"id":"https://openalex.org/keywords/rendering","display_name":"Rendering (computer graphics)","score":0.6733181476593018},{"id":"https://openalex.org/keywords/microscope","display_name":"Microscope","score":0.6096380949020386},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.603740394115448},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5636953115463257},{"id":"https://openalex.org/keywords/interactive-visualization","display_name":"Interactive visualization","score":0.4415942430496216},{"id":"https://openalex.org/keywords/computer-graphics","display_name":"Computer graphics (images)","score":0.4108458459377289},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.19212308526039124},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.09866523742675781}],"concepts":[{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.7824304103851318},{"id":"https://openalex.org/C30769735","wikidata":"https://www.wikidata.org/wiki/Q2165951","display_name":"Volume rendering","level":3,"score":0.7645741701126099},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7243450284004211},{"id":"https://openalex.org/C205711294","wikidata":"https://www.wikidata.org/wiki/Q176953","display_name":"Rendering (computer graphics)","level":2,"score":0.6733181476593018},{"id":"https://openalex.org/C67649825","wikidata":"https://www.wikidata.org/wiki/Q196538","display_name":"Microscope","level":2,"score":0.6096380949020386},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.603740394115448},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5636953115463257},{"id":"https://openalex.org/C64073096","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Interactive visualization","level":3,"score":0.4415942430496216},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.4108458459377289},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.19212308526039124},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09866523742675781}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001808","descriptor_name":"Blood Vessels","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001808","descriptor_name":"Blood Vessels","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001808","descriptor_name":"Blood Vessels","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003712","descriptor_name":"Dendrites","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003712","descriptor_name":"Dendrites","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003712","descriptor_name":"Dendrites","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12859-014-0415-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-014-0415-x","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-014-0415-x","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:25523409","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25523409","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:irdb.nii.ac.jp:01221:0000155595","is_oa":true,"landing_page_url":"http://hdl.handle.net/2433/196840","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":"journal article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4279998","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4279998","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12859-014-0415-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-014-0415-x","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-014-0415-x","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G6873897576","display_name":null,"funder_award_id":"24680059","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2062075449.pdf","grobid_xml":"https://content.openalex.org/works/W2062075449.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W15287949","https://openalex.org/W197029716","https://openalex.org/W1983553517","https://openalex.org/W1988971265","https://openalex.org/W1989045141","https://openalex.org/W2015487456","https://openalex.org/W2016307765","https://openalex.org/W2018227909","https://openalex.org/W2018709063","https://openalex.org/W2026423592","https://openalex.org/W2046591691","https://openalex.org/W2050128276","https://openalex.org/W2065637891","https://openalex.org/W2084834254","https://openalex.org/W2088880356","https://openalex.org/W2096373083","https://openalex.org/W2104276184","https://openalex.org/W2104441030","https://openalex.org/W2109845109","https://openalex.org/W2115876851","https://openalex.org/W2122140178","https://openalex.org/W2126521141","https://openalex.org/W2127534511","https://openalex.org/W2129534965","https://openalex.org/W2131414754","https://openalex.org/W2138867322","https://openalex.org/W2148087487","https://openalex.org/W2161730051","https://openalex.org/W2162106299","https://openalex.org/W2162407586","https://openalex.org/W2163363303","https://openalex.org/W2166928043","https://openalex.org/W2170839387"],"related_works":["https://openalex.org/W1982370580","https://openalex.org/W2739976646","https://openalex.org/W1486114612","https://openalex.org/W2009088896","https://openalex.org/W2006240110","https://openalex.org/W2909972699","https://openalex.org/W2751110224","https://openalex.org/W2039602384","https://openalex.org/W2496664377","https://openalex.org/W4312613920"],"abstract_inverted_index":{"BACKGROUND:":[0],"Recent":[1],"advances":[2],"in":[3,58,132,207,213,219],"microscopy":[4],"enable":[5],"the":[6,28,33,39,48,51,59,89,104,120,133,145,161,229,237,243],"acquisition":[7],"of":[8,11,71,106,188,202],"large":[9],"numbers":[10],"tomographic":[12],"images":[13,19,63,171,210],"from":[14,35,65,173],"living":[15,174],"tissues.":[16,108],"Three-dimensional":[17],"microscope":[18,170,209],"are":[20,123],"often":[21],"displayed":[22],"with":[23,79,150],"volume":[24,205],"rendering":[25,206],"by":[26,118,204,228,242],"adjusting":[27],"transfer":[29,90,121,232],"functions.":[30],"However,":[31],"because":[32],"emissions":[34],"fluorescent":[36],"materials":[37],"and":[38,77,82,126,148,176,234],"optical":[40],"properties":[41],"based":[42,128],"on":[43,129,160],"point":[44],"spread":[45],"functions":[46,91,122],"affect":[47],"imaging":[49],"results,":[50],"intensity":[52],"value":[53],"can":[54,157,239],"differ":[55],"locally,":[56],"even":[57],"same":[60],"structure.":[61],"Further,":[62],"obtained":[64],"brain":[66],"tissues":[67],"contain":[68],"a":[69,220],"variety":[70],"neural":[72],"structures":[73,149,217],"such":[74],"as":[75],"dendrites":[76],"axons":[78],"complex":[80,221],"crossings":[81],"overlapping":[83,189],"linear":[84,215],"structures.":[85,191],"In":[86],"these":[87,107],"cases,":[88],"previously":[92],"used":[93],"fail":[94],"to":[95,102,142,179,245],"optimize":[96],"image":[97],"generation,":[98],"making":[99],"it":[100],"difficult":[101],"explore":[103],"connectivity":[105],"RESULTS:":[109],"This":[110,164],"paper":[111],"proposes":[112],"an":[113,181],"interactive":[114,185,194],"visual":[115,186],"exploration":[116,187],"method":[117,165,183,196,225],"which":[119,214],"modified":[124],"locally":[125],"interactively":[127],"multidimensional":[130,231],"features":[131],"images.":[134],"A":[135],"direct":[136],"editing":[137],"interface":[138,235],"is":[139,166,177,226],"also":[140],"provided":[141],"specify":[143],"both":[144],"target":[146],"region":[147],"characteristic":[151],"features,":[152],"where":[153,236],"all":[154],"manual":[155],"operations":[156],"be":[158,180,240],"performed":[159],"rendered":[162],"image.":[163],"demonstrated":[167],"using":[168],"two-photon":[169,208],"acquired":[172],"mice,":[175],"shown":[178],"effective":[182],"for":[184,199],"similar":[190],"CONCLUSIONS:":[192],"An":[193],"visualization":[195,203,249],"was":[197],"introduced":[198],"local":[200],"improvement":[201],"containing":[211],"regions":[212],"nerve":[216],"crisscross":[218],"manner.":[222],"The":[223],"proposed":[224],"characterized":[227],"localized":[230],"function":[233],"parameters":[238],"determined":[241],"user":[244],"suit":[246],"their":[247],"particular":[248],"requirements.":[250]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}