{"id":"https://openalex.org/W2145210171","doi":"https://doi.org/10.1186/1758-2946-6-s1-o9","title":"Development of cannabinoid receptor (CB 2 R) ligands for application in PET studies - where to attach the radiolabel?","display_name":"Development of cannabinoid receptor (CB 2 R) ligands for application in PET studies - where to attach the radiolabel?","publication_year":2014,"publication_date":"2014-03-01","ids":{"openalex":"https://openalex.org/W2145210171","doi":"https://doi.org/10.1186/1758-2946-6-s1-o9","mag":"2145210171","pmid":"https://pubmed.ncbi.nlm.nih.gov/24765132"},"language":"en","primary_location":{"id":"doi:10.1186/1758-2946-6-s1-o9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1758-2946-6-s1-o9","pdf_url":"https://link.springer.com/content/pdf/10.1186/1758-2946-6-S1-O9.pdf","source":{"id":"https://openalex.org/S180838163","display_name":"Journal of Cheminformatics","issn_l":"1758-2946","issn":["1758-2946"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cheminformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/1758-2946-6-S1-O9.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012266607","display_name":"Robert G\u00fcnther","orcid":"https://orcid.org/0000-0002-3533-9747"},"institutions":[{"id":"https://openalex.org/I2801798921","display_name":"Helmholtz-Zentrum Dresden-Rossendorf","ror":"https://ror.org/01zy2cs03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I2801798921"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Robert G\u00fcnther","raw_affiliation_strings":["Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, 04368 Germany","Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, 04368 Germany","institution_ids":["https://openalex.org/I2801798921"]},{"raw_affiliation_string":"Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, Germany","institution_ids":["https://openalex.org/I2801798921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086853862","display_name":"Rare\u015f\u2010Petru Moldovan","orcid":"https://orcid.org/0000-0003-3119-7945"},"institutions":[{"id":"https://openalex.org/I2801798921","display_name":"Helmholtz-Zentrum Dresden-Rossendorf","ror":"https://ror.org/01zy2cs03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I2801798921"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Rare\u015f Moldovan","raw_affiliation_strings":["Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, 04368 Germany","Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, 04368 Germany","institution_ids":["https://openalex.org/I2801798921"]},{"raw_affiliation_string":"Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, Germany","institution_ids":["https://openalex.org/I2801798921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026785730","display_name":"Corinna Lueg","orcid":null},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Corinna Lueg","raw_affiliation_strings":["Department of Pharmaceutical and Medicinal Chemistry, University of M\u00fcnster, M\u00fcnster, 48149 Germany","Department of Pharmaceutical and Medicinal Chemistry, University of M\u00fcnster, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical and Medicinal Chemistry, University of M\u00fcnster, M\u00fcnster, 48149 Germany","institution_ids":["https://openalex.org/I22465464"]},{"raw_affiliation_string":"Department of Pharmaceutical and Medicinal Chemistry, University of M\u00fcnster, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053568782","display_name":"Winnie Deuther\u2010Conrad","orcid":"https://orcid.org/0000-0003-3168-3062"},"institutions":[{"id":"https://openalex.org/I2801798921","display_name":"Helmholtz-Zentrum Dresden-Rossendorf","ror":"https://ror.org/01zy2cs03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I2801798921"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Winnie Deuther-Conrad","raw_affiliation_strings":["Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, 04368 Germany","Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, 04368 Germany","institution_ids":["https://openalex.org/I2801798921"]},{"raw_affiliation_string":"Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, Germany","institution_ids":["https://openalex.org/I2801798921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040260186","display_name":"Bernhard W\u00fcnsch","orcid":"https://orcid.org/0000-0002-9030-8417"},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bernhard W\u00fcnsch","raw_affiliation_strings":["Department of Pharmaceutical and Medicinal Chemistry, University of M\u00fcnster, M\u00fcnster, 48149 Germany","Department of Pharmaceutical and Medicinal Chemistry, University of M\u00fcnster, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical and Medicinal Chemistry, University of M\u00fcnster, M\u00fcnster, 48149 Germany","institution_ids":["https://openalex.org/I22465464"]},{"raw_affiliation_string":"Department of Pharmaceutical and Medicinal Chemistry, University of M\u00fcnster, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073720321","display_name":"Peter Brust","orcid":"https://orcid.org/0000-0001-5555-7058"},"institutions":[{"id":"https://openalex.org/I2801798921","display_name":"Helmholtz-Zentrum Dresden-Rossendorf","ror":"https://ror.org/01zy2cs03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I2801798921"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Peter Brust","raw_affiliation_strings":["Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, 04368 Germany","Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, 04368 Germany","institution_ids":["https://openalex.org/I2801798921"]},{"raw_affiliation_string":"Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, Germany","institution_ids":["https://openalex.org/I2801798921"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5012266607"],"corresponding_institution_ids":["https://openalex.org/I2801798921"],"apc_list":{"value":1290,"currency":"GBP","value_usd":1582},"apc_paid":{"value":1290,"currency":"GBP","value_usd":1582},"fwci":0.427,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.64771281,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"6","issue":"S1","first_page":"O9","last_page":"O9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13047","display_name":"Pharmacological Receptor Mechanisms and Effects","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13047","display_name":"Pharmacological Receptor Mechanisms and Effects","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10414","display_name":"Cannabis and Cannabinoid Research","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cannabinoid-receptor","display_name":"Cannabinoid receptor","score":0.7072242498397827},{"id":"https://openalex.org/keywords/positron-emission-tomography","display_name":"Positron emission tomography","score":0.6553028225898743},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.6530279517173767},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.6138715147972107},{"id":"https://openalex.org/keywords/cannabinoid","display_name":"Cannabinoid","score":0.5645700097084045},{"id":"https://openalex.org/keywords/high-resolution","display_name":"High resolution","score":0.5355173945426941},{"id":"https://openalex.org/keywords/ligand","display_name":"Ligand (biochemistry)","score":0.5105860829353333},{"id":"https://openalex.org/keywords/docking","display_name":"Docking (animal)","score":0.4960263669490814},{"id":"https://openalex.org/keywords/carbazole","display_name":"Carbazole","score":0.4156852960586548},{"id":"https://openalex.org/keywords/stereochemistry","display_name":"Stereochemistry","score":0.366502046585083},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.2720034122467041},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.20748716592788696},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1692296266555786},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.13765284419059753},{"id":"https://openalex.org/keywords/antagonist","display_name":"Antagonist","score":0.12789171934127808}],"concepts":[{"id":"https://openalex.org/C148001335","wikidata":"https://www.wikidata.org/wiki/Q421237","display_name":"Cannabinoid receptor","level":4,"score":0.7072242498397827},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.6553028225898743},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6530279517173767},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6138715147972107},{"id":"https://openalex.org/C2780871563","wikidata":"https://www.wikidata.org/wiki/Q422936","display_name":"Cannabinoid","level":3,"score":0.5645700097084045},{"id":"https://openalex.org/C3020199158","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"High resolution","level":2,"score":0.5355173945426941},{"id":"https://openalex.org/C116569031","wikidata":"https://www.wikidata.org/wiki/Q899107","display_name":"Ligand (biochemistry)","level":3,"score":0.5105860829353333},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.4960263669490814},{"id":"https://openalex.org/C2776127813","wikidata":"https://www.wikidata.org/wiki/Q424003","display_name":"Carbazole","level":2,"score":0.4156852960586548},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.366502046585083},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2720034122467041},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.20748716592788696},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1692296266555786},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.13765284419059753},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.12789171934127808},{"id":"https://openalex.org/C62649853","wikidata":"https://www.wikidata.org/wiki/Q199687","display_name":"Remote sensing","level":1,"score":0.0},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1186/1758-2946-6-s1-o9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1758-2946-6-s1-o9","pdf_url":"https://link.springer.com/content/pdf/10.1186/1758-2946-6-S1-O9.pdf","source":{"id":"https://openalex.org/S180838163","display_name":"Journal of Cheminformatics","issn_l":"1758-2946","issn":["1758-2946"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cheminformatics","raw_type":"journal-article"},{"id":"pmid:24765132","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24765132","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cheminformatics","raw_type":null},{"id":"pmh:oai:europepmc.org:2972165","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3980078","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1758-2946-6-s1-o9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1758-2946-6-s1-o9","pdf_url":"https://link.springer.com/content/pdf/10.1186/1758-2946-6-S1-O9.pdf","source":{"id":"https://openalex.org/S180838163","display_name":"Journal of Cheminformatics","issn_l":"1758-2946","issn":["1758-2946"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cheminformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2145210171.pdf","grobid_xml":"https://content.openalex.org/works/W2145210171.grobid-xml"},"referenced_works_count":4,"referenced_works":["https://openalex.org/W370006293","https://openalex.org/W2105237446","https://openalex.org/W2123149027","https://openalex.org/W2142823426"],"related_works":["https://openalex.org/W2245953918","https://openalex.org/W2079025265","https://openalex.org/W2124754186","https://openalex.org/W1991461690","https://openalex.org/W2012942066","https://openalex.org/W2009732294","https://openalex.org/W2051367597","https://openalex.org/W2070592640","https://openalex.org/W1999203299","https://openalex.org/W1994598079"],"abstract_inverted_index":{"The":[0,121],"cannabinoid":[1],"receptors":[2],"type":[3],"2":[4,130,192],"(CB2R)":[5],"are":[6],"involved":[7],"in":[8,16,48,57,89,165],"many":[9],"physiological":[10],"processes":[11],"but":[12],"their":[13],"expression":[14],"level":[15],"healthy":[17],"and":[18,67,80,131,182,191],"diseased":[19],"brain":[20],"has":[21],"not":[22,159],"been":[23],"unravelled.":[24],"With":[25],"positron":[26,43],"emission":[27],"tomography":[28],"(PET)":[29],"it":[30],"is":[31],"possible":[32],"to":[33,63,69,104,161],"monitor":[34],"quantitatively":[35],"very":[36],"low":[37],"amounts":[38],"of":[39,74,149,155,198],"compounds":[40],"labelled":[41],"with":[42,100,167],"emitting":[44],"isotopes":[45],"like":[46],"18F":[47],"living":[49],"organisms":[50],"at":[51,152],"high":[52,65],"spatial":[53],"resolution.":[54],"For":[55],"application":[56],"clinical":[58],"research,":[59],"such":[60],"radiotracers":[61],"have":[62],"show":[64],"selectivity":[66],"affinity":[68,82],"the":[70,81,84,110,126,132,145,150,156,168,186,195,199],"target":[71],"protein.\r\n\r\nA":[72],"series":[73],"fluorinated":[75],"N-carbazolyl-oxadiazolyl-propionamides":[76],"[1]":[77],"was":[78,87],"synthesised":[79],"towards":[83],"human":[85],"CB2R":[86,97,200],"measured":[88],"receptor":[90,98,201],"binding":[91,146,196],"studies.":[92],"Here,":[93],"we":[94],"combine":[95],"our":[96,177],"model":[99],"3D-QSAR":[101],"data":[102],"[2]":[103],"support":[105],"molecular":[106],"docking":[107],"studies":[108,122,173],"employing":[109],"MOE":[111],"software":[112],"(Version":[113],"2012.12":[114],"Chemical":[115],"Computing":[116],"Group":[117],"Inc.":[118],"Montreal.":[119],"http://www.chemcomp.com).":[120],"revealed":[123],"that":[124,180],"both":[125],"primarily":[127],"investigated":[128],"compound":[129],"2-fluoroethyl":[133],"substituted":[134],"carbazole":[135],"derivative":[136],"1":[137,190],"(Ki":[138],"=":[139],"3.6":[140],"nM)":[141],"fits":[142],"well":[143],"into":[144,194],"pocket.":[147],"Attachment":[148],"fluorine":[151],"different":[153,163],"positions":[154],"structure":[157],"does":[158],"lead":[160],"significantly":[162],"poses":[164],"accordance":[166],"experimental":[169],"data.":[170],"Organ":[171],"distribution":[172],"on":[174],"CD1-mice":[175],"verified":[176],"prediction,":[178],"[3]":[179],"[18F]1":[181],"[18F]2":[183],"can":[184],"cross":[185],"blood-brain":[187],"barrier.\r\n\r\n\r\n\r\nFigure":[188],"1\r\n\r\nCompounds":[189],"fitted":[193],"pocket":[197],"model.":[202]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-06-16T07:32:37.131356","created_date":"2025-10-10T00:00:00"}