{"id":"https://openalex.org/W2101279094","doi":"https://doi.org/10.1186/1756-0381-7-17","title":"Computational genetics analysis of grey matter density in Alzheimer\u2019s disease","display_name":"Computational genetics analysis of grey matter density in Alzheimer\u2019s disease","publication_year":2014,"publication_date":"2014-08-22","ids":{"openalex":"https://openalex.org/W2101279094","doi":"https://doi.org/10.1186/1756-0381-7-17","mag":"2101279094","pmid":"https://pubmed.ncbi.nlm.nih.gov/25165488"},"language":"en","primary_location":{"id":"doi:10.1186/1756-0381-7-17","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1756-0381-7-17","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/1756-0381-7-17","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/1756-0381-7-17","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040678291","display_name":"Amanda Zieselman","orcid":null},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Amanda L Zieselman","raw_affiliation_strings":["Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","institution_ids":["https://openalex.org/I107672454"]},{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025883825","display_name":"Jonathan Fisher","orcid":null},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan M Fisher","raw_affiliation_strings":["Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","institution_ids":["https://openalex.org/I107672454"]},{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101965823","display_name":"Ting Hu","orcid":null},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ting Hu","raw_affiliation_strings":["Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","institution_ids":["https://openalex.org/I107672454"]},{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035649015","display_name":"Peter C. Andrews","orcid":null},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter C Andrews","raw_affiliation_strings":["Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","institution_ids":["https://openalex.org/I107672454"]},{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050692257","display_name":"Casey S. Greene","orcid":"https://orcid.org/0000-0001-8713-9213"},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Casey S Greene","raw_affiliation_strings":["Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","institution_ids":["https://openalex.org/I107672454"]},{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100333320","display_name":"Li Shen","orcid":"https://orcid.org/0000-0002-5443-0503"},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":null,"type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Li Shen","raw_affiliation_strings":["Department of Radiology and Imaging Sciences, Center for Neuroimaging and Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA","Department of Radiology and Imaging Sciences, Center for Neuroimaging and Indiana Alzheimer\u2019s Disease Center, Indiana University School of Medicine, Indianapolis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Imaging Sciences, Center for Neuroimaging and Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology and Imaging Sciences, Center for Neuroimaging and Indiana Alzheimer\u2019s Disease Center, Indiana University School of Medicine, Indianapolis, USA","institution_ids":["https://openalex.org/I55769427","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026257338","display_name":"Andrew J. Saykin","orcid":"https://orcid.org/0000-0002-1376-8532"},"institutions":[{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":null,"type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew J Saykin","raw_affiliation_strings":["Department of Radiology and Imaging Sciences, Center for Neuroimaging and Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA","Department of Radiology and Imaging Sciences, Center for Neuroimaging and Indiana Alzheimer\u2019s Disease Center, Indiana University School of Medicine, Indianapolis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Imaging Sciences, Center for Neuroimaging and Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology and Imaging Sciences, Center for Neuroimaging and Indiana Alzheimer\u2019s Disease Center, Indiana University School of Medicine, Indianapolis, USA","institution_ids":["https://openalex.org/I55769427","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032971510","display_name":"Jason H. Moore","orcid":"https://orcid.org/0000-0002-5015-1099"},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason H Moore","raw_affiliation_strings":["Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA","institution_ids":["https://openalex.org/I107672454"]},{"raw_affiliation_string":"Department of Genetics, Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Hanover, USA","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"last","author":{"id":null,"display_name":"for the Alzheimer\u2019s Disease Neuroimaging Initiative","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"for the Alzheimer\u2019s Disease Neuroimaging Initiative","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5040678291"],"corresponding_institution_ids":["https://openalex.org/I107672454"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.6517,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.63231145,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"7","issue":"1","first_page":"17","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.3522000014781952,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.3522000014781952,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.1688999980688095,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.061900001019239426,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/grey-matter","display_name":"Grey matter","score":0.5897447466850281},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5794917345046997},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.40279167890548706},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3297230005264282},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3223305344581604},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2732475996017456},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2453376054763794},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.11474034190177917}],"concepts":[{"id":"https://openalex.org/C2778013878","wikidata":"https://www.wikidata.org/wiki/Q646150","display_name":"Grey matter","level":4,"score":0.5897447466850281},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5794917345046997},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.40279167890548706},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3297230005264282},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3223305344581604},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2732475996017456},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2453376054763794},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11474034190177917},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.0},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1186/1756-0381-7-17","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1756-0381-7-17","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/1756-0381-7-17","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},{"id":"pmid:25165488","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25165488","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData mining","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:4145360","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4145360","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioData Min","raw_type":"Text"},{"id":"pmh:oai:scholarworks.indianapolis.iu.edu:1805/46720","is_oa":true,"landing_page_url":"https://hdl.handle.net/1805/46720","pdf_url":null,"source":{"id":"https://openalex.org/S4306400987","display_name":"IUScholarWorks (Indiana University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I592451","host_organization_name":"Indiana University","host_organization_lineage":["https://openalex.org/I592451"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PMC","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1186/1756-0381-7-17","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1756-0381-7-17","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/1756-0381-7-17","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1012222616","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320309432","funder_display_name":"F. Hoffmann-La Roche"},{"id":"https://openalex.org/G1131972899","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G1336222015","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1554142629","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320322148","funder_display_name":"Eisai"},{"id":"https://openalex.org/G1593117279","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320309470","funder_display_name":"Meso Scale Diagnostics"},{"id":"https://openalex.org/G1650819308","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320308604","funder_display_name":"Biogen"},{"id":"https://openalex.org/G1823308732","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320306080","funder_display_name":"Foundation for the National Institutes of Health"},{"id":"https://openalex.org/G2100670906","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320310388","funder_display_name":"Novartis Pharmaceuticals Corporation"},{"id":"https://openalex.org/G2152643862","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320311551","funder_display_name":"Northern California Institute for Research and Education"},{"id":"https://openalex.org/G2189010064","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320306078","funder_display_name":"U.S. Department of Defense"},{"id":"https://openalex.org/G2340207221","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320310045","funder_display_name":"BioClinica"},{"id":"https://openalex.org/G2409989180","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320309546","funder_display_name":"Synarc"},{"id":"https://openalex.org/G2522063444","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320332193","funder_display_name":"Genentech"},{"id":"https://openalex.org/G2822121521","display_name":null,"funder_award_id":"LM009012","funder_id":"https://openalex.org/F4320306080","funder_display_name":"Foundation for the National Institutes of Health"},{"id":"https://openalex.org/G299099718","display_name":null,"funder_award_id":"LM009012","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G29951154","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320309697","funder_display_name":"Alzheimer's Disease Neuroimaging Initiative"},{"id":"https://openalex.org/G3130427885","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G3131374986","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320307115","funder_display_name":"Bristol-Myers Squibb"},{"id":"https://openalex.org/G3216574877","display_name":null,"funder_award_id":"W81XWH-12-2-","funder_id":"https://openalex.org/F4320309697","funder_display_name":"Alzheimer's Disease Neuroimaging Initiative"},{"id":"https://openalex.org/G3553156159","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320307115","funder_display_name":"Bristol-Myers Squibb"},{"id":"https://openalex.org/G3710456697","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320307758","funder_display_name":"Eli Lilly and Company"},{"id":"https://openalex.org/G3752451908","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320327235","funder_display_name":"Servier"},{"id":"https://openalex.org/G3870774570","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320332193","funder_display_name":"Genentech"},{"id":"https://openalex.org/G3890809913","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320309697","funder_display_name":"Alzheimer's Disease Neuroimaging Initiative"},{"id":"https://openalex.org/G3908963977","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G3966393351","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320309432","funder_display_name":"F. Hoffmann-La Roche"},{"id":"https://openalex.org/G3967336437","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G4119534169","display_name":null,"funder_award_id":"W81XWH","funder_id":"https://openalex.org/F4320306078","funder_display_name":"U.S. Department of Defense"},{"id":"https://openalex.org/G43180419","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320322148","funder_display_name":"Eisai"},{"id":"https://openalex.org/G4401988282","display_name":null,"funder_award_id":"Grant U01 AG024904","funder_id":"https://openalex.org/F4320306080","funder_display_name":"Foundation for the National Institutes of Health"},{"id":"https://openalex.org/G4475667458","display_name":null,"funder_award_id":"W81XWH-12-2-","funder_id":"https://openalex.org/F4320306078","funder_display_name":"U.S. Department of Defense"},{"id":"https://openalex.org/G4501223628","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320329118","funder_display_name":"IXICO"},{"id":"https://openalex.org/G4558216502","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4800177743","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320310045","funder_display_name":"BioClinica"},{"id":"https://openalex.org/G4860885537","display_name":null,"funder_award_id":"Department of Defense award number W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320309697","funder_display_name":"Alzheimer's Disease Neuroimaging Initiative"},{"id":"https://openalex.org/G5207404921","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320306219","funder_display_name":"Alzheimer's Association"},{"id":"https://openalex.org/G5209990037","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320307765","funder_display_name":"Pfizer"},{"id":"https://openalex.org/G528601746","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G5365730499","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320308668","funder_display_name":"University of Southern California"},{"id":"https://openalex.org/G5389965057","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G5654639750","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320310045","funder_display_name":"BioClinica"},{"id":"https://openalex.org/G5740349702","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320309470","funder_display_name":"Meso Scale Diagnostics"},{"id":"https://openalex.org/G5850682332","display_name":null,"funder_award_id":"W81XWH","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G613619302","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320310388","funder_display_name":"Novartis Pharmaceuticals Corporation"},{"id":"https://openalex.org/G6173816828","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320307765","funder_display_name":"Pfizer"},{"id":"https://openalex.org/G6210868510","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320308604","funder_display_name":"Biogen"},{"id":"https://openalex.org/G6345136743","display_name":null,"funder_award_id":"LM011360","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6371410416","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320308604","funder_display_name":"Biogen"},{"id":"https://openalex.org/G6412110892","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320332193","funder_display_name":"Genentech"},{"id":"https://openalex.org/G6447063303","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320309470","funder_display_name":"Meso Scale Diagnostics"},{"id":"https://openalex.org/G6608586327","display_name":null,"funder_award_id":"GM103506","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6682602594","display_name":null,"funder_award_id":"LM010098","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6719828067","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320329118","funder_display_name":"IXICO"},{"id":"https://openalex.org/G6789252168","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6792506723","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320307115","funder_display_name":"Bristol-Myers Squibb"},{"id":"https://openalex.org/G6812249457","display_name":null,"funder_award_id":"Grant U01 AG024904","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6899163935","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320322148","funder_display_name":"Eisai"},{"id":"https://openalex.org/G6948409098","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320309432","funder_display_name":"F. Hoffmann-La Roche"},{"id":"https://openalex.org/G72415811","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320311551","funder_display_name":"Northern California Institute for Research and Education"},{"id":"https://openalex.org/G7298697282","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320329118","funder_display_name":"IXICO"},{"id":"https://openalex.org/G7414321945","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320306080","funder_display_name":"Foundation for the National Institutes of Health"},{"id":"https://openalex.org/G7463692367","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320306080","funder_display_name":"Foundation for the National Institutes of Health"},{"id":"https://openalex.org/G764699806","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7799614282","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320307765","funder_display_name":"Pfizer"},{"id":"https://openalex.org/G781725486","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320307758","funder_display_name":"Eli Lilly and Company"},{"id":"https://openalex.org/G7854119329","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320306078","funder_display_name":"U.S. Department of Defense"},{"id":"https://openalex.org/G7965638068","display_name":null,"funder_award_id":"GM103534","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8228018387","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320306219","funder_display_name":"Alzheimer's Association"},{"id":"https://openalex.org/G8281378126","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320327235","funder_display_name":"Servier"},{"id":"https://openalex.org/G8288036582","display_name":null,"funder_award_id":"NIH R01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G839208290","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320310388","funder_display_name":"Novartis Pharmaceuticals Corporation"},{"id":"https://openalex.org/G8636843673","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320309466","funder_display_name":"Medpace"},{"id":"https://openalex.org/G8852128998","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320327235","funder_display_name":"Servier"},{"id":"https://openalex.org/G8895907669","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320306078","funder_display_name":"U.S. Department of Defense"},{"id":"https://openalex.org/G8897063270","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320308668","funder_display_name":"University of Southern California"},{"id":"https://openalex.org/G8940068167","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320309697","funder_display_name":"Alzheimer's Disease Neuroimaging Initiative"},{"id":"https://openalex.org/G8957659042","display_name":null,"funder_award_id":"W81XWH-12-2-0012","funder_id":"https://openalex.org/F4320307758","funder_display_name":"Eli Lilly and Company"},{"id":"https://openalex.org/G920654007","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"}],"funders":[{"id":"https://openalex.org/F4320306078","display_name":"U.S. Department of Defense","ror":"https://ror.org/0447fe631"},{"id":"https://openalex.org/F4320306080","display_name":"Foundation for the National Institutes of Health","ror":"https://ror.org/00k86s890"},{"id":"https://openalex.org/F4320306219","display_name":"Alzheimer's Association","ror":"https://ror.org/0375f4d26"},{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"},{"id":"https://openalex.org/F4320307758","display_name":"Eli Lilly and Company","ror":"https://ror.org/01qat3289"},{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F4320308604","display_name":"Biogen","ror":"https://ror.org/02jqkb192"},{"id":"https://openalex.org/F4320308668","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60"},{"id":"https://openalex.org/F4320309432","display_name":"F. Hoffmann-La Roche","ror":"https://ror.org/00by1q217"},{"id":"https://openalex.org/F4320309466","display_name":"Medpace","ror":"https://ror.org/05mgcmd27"},{"id":"https://openalex.org/F4320309470","display_name":"Meso Scale Diagnostics","ror":"https://ror.org/05jgy0m16"},{"id":"https://openalex.org/F4320309546","display_name":"Synarc","ror":"https://ror.org/03t95yr58"},{"id":"https://openalex.org/F4320309697","display_name":"Alzheimer's Disease Neuroimaging Initiative","ror":"https://ror.org/01j20wc74"},{"id":"https://openalex.org/F4320310045","display_name":"BioClinica","ror":"https://ror.org/03t95yr58"},{"id":"https://openalex.org/F4320310388","display_name":"Novartis Pharmaceuticals Corporation","ror":"https://ror.org/028fhxy95"},{"id":"https://openalex.org/F4320310400","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22"},{"id":"https://openalex.org/F4320311551","display_name":"Northern California Institute for Research and Education","ror":"https://ror.org/05p48p517"},{"id":"https://openalex.org/F4320322148","display_name":"Eisai","ror":"https://ror.org/04vvh7p27"},{"id":"https://openalex.org/F4320327235","display_name":"Servier","ror":"https://ror.org/034e7c066"},{"id":"https://openalex.org/F4320329118","display_name":"IXICO","ror":"https://ror.org/00paezp73"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332193","display_name":"Genentech","ror":"https://ror.org/04gndp242"},{"id":"https://openalex.org/F4320332603","display_name":"University of California, San Diego","ror":"https://ror.org/0168r3w48"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2101279094.pdf","grobid_xml":"https://content.openalex.org/works/W2101279094.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W1957741858","https://openalex.org/W1998481523","https://openalex.org/W2007044705","https://openalex.org/W2012069179","https://openalex.org/W2017079501","https://openalex.org/W2029843395","https://openalex.org/W2030628077","https://openalex.org/W2048674585","https://openalex.org/W2052968292","https://openalex.org/W2076011171","https://openalex.org/W2076220518","https://openalex.org/W2082503383","https://openalex.org/W2095243453","https://openalex.org/W2097508746","https://openalex.org/W2110496823","https://openalex.org/W2111679543","https://openalex.org/W2135233920","https://openalex.org/W2141073802","https://openalex.org/W2145068263","https://openalex.org/W2154572047","https://openalex.org/W2166348468","https://openalex.org/W4249565903"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2134237591","https://openalex.org/W1595276058","https://openalex.org/W2082094717","https://openalex.org/W3003967560","https://openalex.org/W2149940328","https://openalex.org/W2675012693","https://openalex.org/W4234240715","https://openalex.org/W2044166387","https://openalex.org/W4205866527"],"abstract_inverted_index":{"BACKGROUND:":[0],"Alzheimer's":[1,56,125,132,181],"disease":[2,133,182,206],"is":[3,13,22,154],"the":[4,43,89,141,174,177,185,189,200],"most":[5],"common":[6],"form":[7],"of":[8,20,46,64,92,131,140,150,176,180,191,203],"progressive":[9],"dementia":[10],"and":[11,115,160,207],"there":[12],"currently":[14],"no":[15],"known":[16],"cure.":[17],"The":[18],"cause":[19],"onset":[21,55],"not":[23,100],"fully":[24],"understood":[25],"but":[26],"genetic":[27,44,129,178,201],"factors":[28],"are":[29,116],"expected":[30],"to":[31,42,145,157],"play":[32],"a":[33,39,79,137,167],"significant":[34,81],"role.":[35],"We":[36,77,163],"present":[37],"here":[38,166],"bioinformatics":[40,169],"approach":[41,59],"analysis":[45,63,170],"grey":[47],"matter":[48],"density":[49],"as":[50],"an":[51,93,103],"endophenotype":[52],"for":[53,72],"late":[54],"disease.":[57,126],"Our":[58],"combines":[60],"machine":[61],"learning":[62],"gene-gene":[65,159],"interactions":[66],"with":[67,118],"large-scale":[68],"functional":[69,192],"genomics":[70],"data":[71],"assessing":[73],"biological":[74,113],"relationships.":[75],"RESULTS:":[76],"found":[78],"statistically":[80],"synergistic":[82],"interaction":[83],"among":[84],"two":[85],"SNPs":[86],"located":[87],"in":[88,102,108,124,215],"intergenic":[90],"region":[91,110],"olfactory":[94],"gene":[95],"cluster.":[96],"This":[97],"model":[98],"did":[99],"replicate":[101],"independent":[104],"dataset.":[105],"However,":[106],"genes":[107],"this":[109,151,204],"have":[111,134,164],"high-confidence":[112],"relationships":[114],"consistent":[117],"previous":[119],"findings":[120,195],"implicating":[121],"sensory":[122],"processes":[123],"CONCLUSIONS:":[127],"Previous":[128],"studies":[130],"revealed":[135],"only":[136],"small":[138],"portion":[139],"overall":[142],"variability":[143],"due":[144,156],"DNA":[146],"sequence":[147],"differences.":[148],"Some":[149],"missing":[152],"heritability":[153],"likely":[155],"complex":[158,205],"gene-environment":[161],"interactions.":[162],"introduced":[165],"novel":[168,197],"pipeline":[171],"that":[172,211],"embraces":[173],"complexity":[175],"architecture":[179],"while":[183],"at":[184],"same":[186],"time":[187],"harnessing":[188],"power":[190],"genomics.":[193],"These":[194],"represent":[196],"hypotheses":[198],"about":[199],"basis":[202],"provide":[208],"open-access":[209],"methods":[210],"others":[212],"can":[213],"use":[214],"their":[216],"own":[217],"studies.":[218]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-06-02T09:04:35.204637","created_date":"2025-10-10T00:00:00"}
