{"id":"https://openalex.org/W2167424562","doi":"https://doi.org/10.1186/1752-0509-8-s2-s4","title":"Integrative omics analysis. A study based on Plasmodium falciparum mRNA and protein data","display_name":"Integrative omics analysis. A study based on Plasmodium falciparum mRNA and protein data","publication_year":2014,"publication_date":"2014-03-01","ids":{"openalex":"https://openalex.org/W2167424562","doi":"https://doi.org/10.1186/1752-0509-8-s2-s4","mag":"2167424562","pmid":"https://pubmed.ncbi.nlm.nih.gov/25033389"},"language":"en","primary_location":{"id":"doi:10.1186/1752-0509-8-s2-s4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-8-s2-s4","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-8-S2-S4","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-8-S2-S4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042165276","display_name":"Oana Tomescu","orcid":null},"institutions":[{"id":"https://openalex.org/I4092182","display_name":"Graz University of Technology","ror":"https://ror.org/00d7xrm67","country_code":"AT","type":"education","lineage":["https://openalex.org/I4092182"]},{"id":"https://openalex.org/I4210138243","display_name":"Austrian Centre of Industrial Biotechnology (Austria)","ror":"https://ror.org/03dm7dd93","country_code":"AT","type":"company","lineage":["https://openalex.org/I4210138243"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Oana A Tomescu","raw_affiliation_strings":["Core Facility Bioinformatics, Austrian Centre of Industrial Biotechnology, Graz, Austria","Institute of Genomics and Bioinformatics, Graz University of Technology, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Core Facility Bioinformatics, Austrian Centre of Industrial Biotechnology, Graz, Austria","institution_ids":["https://openalex.org/I4210138243"]},{"raw_affiliation_string":"Institute of Genomics and Bioinformatics, Graz University of Technology, Graz, Austria","institution_ids":["https://openalex.org/I4092182"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050115274","display_name":"Diethard Mattanovich","orcid":"https://orcid.org/0000-0002-0907-4167"},"institutions":[{"id":"https://openalex.org/I4210138243","display_name":"Austrian Centre of Industrial Biotechnology (Austria)","ror":"https://ror.org/03dm7dd93","country_code":"AT","type":"company","lineage":["https://openalex.org/I4210138243"]},{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Diethard Mattanovich","raw_affiliation_strings":["Cell Design and Engineering, Austrian Centre of Industrial Biotechnology, Vienna, Austria","Department of Biotechnology, BOKU-VIBT University of Natural Resources and Life Sciences, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cell Design and Engineering, Austrian Centre of Industrial Biotechnology, Vienna, Austria","institution_ids":["https://openalex.org/I4210138243"]},{"raw_affiliation_string":"Department of Biotechnology, BOKU-VIBT University of Natural Resources and Life Sciences, Vienna, Austria","institution_ids":["https://openalex.org/I92869138"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037209090","display_name":"Gerhard Thallinger","orcid":"https://orcid.org/0000-0002-2864-5404"},"institutions":[{"id":"https://openalex.org/I4210138243","display_name":"Austrian Centre of Industrial Biotechnology (Austria)","ror":"https://ror.org/03dm7dd93","country_code":"AT","type":"company","lineage":["https://openalex.org/I4210138243"]},{"id":"https://openalex.org/I4092182","display_name":"Graz University of Technology","ror":"https://ror.org/00d7xrm67","country_code":"AT","type":"education","lineage":["https://openalex.org/I4092182"]},{"id":"https://openalex.org/I4210097752","display_name":"OMV (Austria)","ror":"https://ror.org/00xn5w219","country_code":"AT","type":"company","lineage":["https://openalex.org/I4210097752"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Gerhard G Thallinger","raw_affiliation_strings":["Core Facility Bioinformatics, Austrian Centre of Industrial Biotechnology, Graz, Austria","Institute of Genomics and Bioinformatics, Graz University of Technology, Graz, Austria","Omics Center Graz, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Core Facility Bioinformatics, Austrian Centre of Industrial Biotechnology, Graz, Austria","institution_ids":["https://openalex.org/I4210138243"]},{"raw_affiliation_string":"Institute of Genomics and Bioinformatics, Graz University of Technology, Graz, Austria","institution_ids":["https://openalex.org/I4092182"]},{"raw_affiliation_string":"Omics Center Graz, Vienna, Austria","institution_ids":["https://openalex.org/I4210097752"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5042165276"],"corresponding_institution_ids":["https://openalex.org/I4092182","https://openalex.org/I4210138243"],"apc_list":null,"apc_paid":null,"fwci":2.6228,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.90128442,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"8","issue":"S2","first_page":"S4","last_page":"S4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.2606000006198883,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.2606000006198883,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.10610000044107437,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13539","display_name":"thermodynamics and calorimetric analyses","score":0.08839999884366989,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6467450261116028},{"id":"https://openalex.org/keywords/biclustering","display_name":"Biclustering","score":0.5871462225914001},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5619471669197083},{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.5136837363243103},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.4594145715236664},{"id":"https://openalex.org/keywords/transcriptome","display_name":"Transcriptome","score":0.4326707720756531},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.43207040429115295},{"id":"https://openalex.org/keywords/singular-value-decomposition","display_name":"Singular value decomposition","score":0.42283743619918823},{"id":"https://openalex.org/keywords/network-analysis","display_name":"Network analysis","score":0.41099822521209717},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.39357030391693115},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.34101712703704834},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3269163966178894},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.2814476490020752},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.2059665322303772},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16981744766235352},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.16125094890594482},{"id":"https://openalex.org/keywords/malaria","display_name":"Malaria","score":0.12647289037704468}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6467450261116028},{"id":"https://openalex.org/C144817290","wikidata":"https://www.wikidata.org/wiki/Q2976575","display_name":"Biclustering","level":5,"score":0.5871462225914001},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5619471669197083},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.5136837363243103},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.4594145715236664},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.4326707720756531},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43207040429115295},{"id":"https://openalex.org/C22789450","wikidata":"https://www.wikidata.org/wiki/Q420904","display_name":"Singular value decomposition","level":2,"score":0.42283743619918823},{"id":"https://openalex.org/C32946077","wikidata":"https://www.wikidata.org/wiki/Q618079","display_name":"Network analysis","level":2,"score":0.41099822521209717},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.39357030391693115},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34101712703704834},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3269163966178894},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.2814476490020752},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2059665322303772},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16981744766235352},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.16125094890594482},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.12647289037704468},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0},{"id":"https://openalex.org/C33704608","wikidata":"https://www.wikidata.org/wiki/Q5014717","display_name":"CURE data clustering algorithm","level":4,"score":0.0},{"id":"https://openalex.org/C94641424","wikidata":"https://www.wikidata.org/wiki/Q5172845","display_name":"Correlation clustering","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D008018","descriptor_name":"Life Cycle Stages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008018","descriptor_name":"Life Cycle Stages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008018","descriptor_name":"Life Cycle Stages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1752-0509-8-s2-s4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-8-s2-s4","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-8-S2-S4","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:25033389","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25033389","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:http://openlib.tugraz.at/564f2dcee468c","is_oa":true,"landing_page_url":"http://openlib.tugraz.at/564f2dcee468c","pdf_url":null,"source":{"id":"https://openalex.org/S4306400660","display_name":"TUGraz OPEN Library (Graz University of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4092182","host_organization_name":"Graz University of Technology","host_organization_lineage":["https://openalex.org/I4092182"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":null},{"id":"pmh:oai:europepmc.org:3072290","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4101701","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1752-0509-8-s2-s4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-8-s2-s4","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-8-S2-S4","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Responsible consumption and production","id":"https://metadata.un.org/sdg/12","score":0.550000011920929}],"awards":[{"id":"https://openalex.org/G3943492410","display_name":null,"funder_award_id":"824186","funder_id":"https://openalex.org/F4320323638","funder_display_name":"Austrian Centre of Industrial Biotechnology"},{"id":"https://openalex.org/G503148373","display_name":null,"funder_award_id":"824186","funder_id":"https://openalex.org/F4320323031","funder_display_name":"\u00d6sterreichische Forschungsf\u00f6rderungsgesellschaft"}],"funders":[{"id":"https://openalex.org/F4320315059","display_name":"Austrian Federal Ministry of Economy, Family and Youth","ror":"https://ror.org/029s7f567"},{"id":"https://openalex.org/F4320323031","display_name":"\u00d6sterreichische Forschungsf\u00f6rderungsgesellschaft","ror":"https://ror.org/028jc0449"},{"id":"https://openalex.org/F4320323638","display_name":"Austrian Centre of Industrial Biotechnology","ror":"https://ror.org/03dm7dd93"},{"id":"https://openalex.org/F4320324794","display_name":"Steirische Wirtschaftsf\u00f6rderungsgesellschaft","ror":"https://ror.org/05x217f96"},{"id":"https://openalex.org/F4320326775","display_name":"Standortagentur Tirol","ror":"https://ror.org/0519vt613"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2167424562.pdf","grobid_xml":"https://content.openalex.org/works/W2167424562.grobid-xml"},"referenced_works_count":76,"referenced_works":["https://openalex.org/W29779864","https://openalex.org/W70448710","https://openalex.org/W183117647","https://openalex.org/W1493217831","https://openalex.org/W1830682242","https://openalex.org/W1963522244","https://openalex.org/W1971912363","https://openalex.org/W1985852691","https://openalex.org/W1987258236","https://openalex.org/W1993946246","https://openalex.org/W2001456353","https://openalex.org/W2001552323","https://openalex.org/W2001554877","https://openalex.org/W2002367806","https://openalex.org/W2005895632","https://openalex.org/W2011578479","https://openalex.org/W2015705446","https://openalex.org/W2018207804","https://openalex.org/W2023461603","https://openalex.org/W2029680375","https://openalex.org/W2030404924","https://openalex.org/W2032896079","https://openalex.org/W2032964150","https://openalex.org/W2036328877","https://openalex.org/W2045234988","https://openalex.org/W2052696562","https://openalex.org/W2056571799","https://openalex.org/W2058849889","https://openalex.org/W2060013178","https://openalex.org/W2064787891","https://openalex.org/W2067913793","https://openalex.org/W2076616438","https://openalex.org/W2082516237","https://openalex.org/W2087962626","https://openalex.org/W2093772131","https://openalex.org/W2094397891","https://openalex.org/W2096945577","https://openalex.org/W2097553067","https://openalex.org/W2098314636","https://openalex.org/W2100417824","https://openalex.org/W2101534062","https://openalex.org/W2102155970","https://openalex.org/W2103017472","https://openalex.org/W2105883975","https://openalex.org/W2108210876","https://openalex.org/W2110583317","https://openalex.org/W2112047656","https://openalex.org/W2115862291","https://openalex.org/W2120403054","https://openalex.org/W2122031538","https://openalex.org/W2126449841","https://openalex.org/W2129256542","https://openalex.org/W2129617994","https://openalex.org/W2132688955","https://openalex.org/W2133241531","https://openalex.org/W2138255346","https://openalex.org/W2141673314","https://openalex.org/W2143423915","https://openalex.org/W2144544802","https://openalex.org/W2144792853","https://openalex.org/W2148541040","https://openalex.org/W2152353895","https://openalex.org/W2155142785","https://openalex.org/W2156022009","https://openalex.org/W2158489365","https://openalex.org/W2163443861","https://openalex.org/W2164312318","https://openalex.org/W2164365774","https://openalex.org/W2171214502","https://openalex.org/W2184417913","https://openalex.org/W2292218180","https://openalex.org/W2582743722","https://openalex.org/W2798909945","https://openalex.org/W3033414884","https://openalex.org/W3099514962","https://openalex.org/W4399583829"],"related_works":["https://openalex.org/W3000738194","https://openalex.org/W2768045943","https://openalex.org/W2088063203","https://openalex.org/W4251593506","https://openalex.org/W2108210876","https://openalex.org/W4206912673","https://openalex.org/W2033995502","https://openalex.org/W2469420430","https://openalex.org/W2010217915","https://openalex.org/W2969238713"],"abstract_inverted_index":{"BACKGROUND:":[0],"Technological":[1],"improvements":[2],"have":[3],"shifted":[4],"the":[5,59,92,113,132,139,153,157,186,192,202,205,266,270,273,277,300,315,340],"focus":[6],"from":[7,20,58,276,291,343],"data":[8,11,19,57,97,143,158],"generation":[9],"to":[10,52,74,103,195],"analysis.":[12],"The":[13,82,304,322],"availability":[14],"of":[15,18,64,94,118,163,172,185,204,214,272,299,326,331,339],"large":[16,337],"amounts":[17],"transcriptomics,":[21],"protemics":[22],"and":[23,46,54,76,79,105,130,141,151,168,226,238,248,255,262,279,294,308],"metabolomics":[24],"experiments":[25],"raise":[26],"new":[27],"questions":[28],"concerning":[29],"suitable":[30],"integrative":[31,37,47,284],"analysis":[32,38,68,71,93,285],"methods.":[33,198],"We":[34,175],"compare":[35],"three":[36,197,206],"techniques":[39],"(co-inertia":[40],"analysis,":[41],"generalized":[42,83],"singular":[43,84],"value":[44,85],"decomposition":[45,86],"biclustering)":[48],"by":[49,156,200],"applying":[50],"them":[51],"gene":[53,78,104],"protein":[55,80,106],"abundance":[56],"six":[60,114],"life":[61,115,169,187,215,327],"cycle":[62,116,170,188,216,275,328],"stages":[63,117,171,189],"Plasmodium":[65,119,173,332],"falciparum.":[66,174],"Co-inertia":[67],"is":[69,311],"an":[70],"method":[72],"used":[73],"visualize":[75,112],"explore":[77,152],"data.":[81,107],"has":[87],"shown":[88],"its":[89],"potential":[90],"in":[91,126,345],"two":[95],"transcriptome":[96],"sets.":[98,159],"Integrative":[99],"Biclustering":[100],"applies":[101],"biclustering":[102],"RESULTS:":[108],"Using":[109,283],"CIA,":[110],"we":[111,137,208,287],"falciparum,":[120],"as":[121,123,179,181,234,236],"well":[122,180,235],"GO":[124,166,219],"terms":[125],"a":[127,182,210,296,336],"2D":[128],"plane":[129],"interpret":[131],"spatial":[133],"configuration.":[134],"With":[135],"GSVD,":[136],"decompose":[138],"transcriptomic":[140],"proteomic":[142],"sets":[144],"into":[145,231],"matrices":[146],"with":[147,224,229,242,246,252,259],"biologically":[148],"meaningful":[149],"interpretations":[150],"processes":[154],"captured":[155],"IBC":[160],"identifies":[161],"groups":[162],"genes,":[164],"proteins,":[165],"Terms":[167],"show":[176],"method-specific":[177,307],"results":[178,193,203,310],"network":[183,213,267,325],"view":[184,298],"based":[190],"on":[191],"common":[194,309],"all":[196],"Additionally,":[199],"combining":[201],"methods,":[207],"create":[209],"three-fold":[211,323],"validated":[212,324],"stage":[217,329],"specific":[218],"terms:":[220],"Sporozoites":[221],"are":[222,319],"associated":[223],"transcription":[225],"transport;":[227],"merozoites":[228],"entry":[230],"host":[232],"cell":[233],"biosynthetic":[237],"metabolic":[239],"processes;":[240,244],"rings":[241],"oxidation-reduction":[243],"trophozoites":[245],"glycolysis":[247],"energy":[249],"production;":[250],"schizonts":[251],"antigenic":[253],"variation":[254],"immune":[256],"response;":[257],"gametocyctes":[258],"DNA":[260],"packaging":[261],"mitochondrial":[263],"transport.":[264],"Furthermore,":[265],"connectivity":[268],"underlines":[269],"separation":[271],"intraerythrocytic":[274],"gametocyte":[278],"sporozoite":[280],"stages.":[281],"CONCLUSION:":[282],"techniques,":[286],"can":[288],"integrate":[289],"knowledge":[290],"different":[292],"levels":[293],"obtain":[295],"wider":[297],"system":[301],"under":[302],"study.":[303,348],"overlap":[305],"between":[306],"considerable,":[312],"even":[313],"if":[314],"basic":[316],"mathematical":[317],"assumptions":[318],"very":[320],"different.":[321],"characteristics":[330],"falciparum":[333],"could":[334],"identify":[335],"amount":[338],"known":[341],"associations":[342],"literature":[344],"only":[346],"one":[347]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}