{"id":"https://openalex.org/W2123482512","doi":"https://doi.org/10.1186/1752-0509-7-s6-s5","title":"Prediction of protein interaction types based on sequence and network features","display_name":"Prediction of protein interaction types based on sequence and network features","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2123482512","doi":"https://doi.org/10.1186/1752-0509-7-s6-s5","mag":"2123482512","pmid":"https://pubmed.ncbi.nlm.nih.gov/24564924"},"language":"en","primary_location":{"id":"doi:10.1186/1752-0509-7-s6-s5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-7-s6-s5","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-7-S6-S5","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-7-S6-S5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060032612","display_name":"Florian Goebels","orcid":null},"institutions":[{"id":"https://openalex.org/I309496635","display_name":"Weihenstephan-Triesdorf University of Applied Sciences","ror":"https://ror.org/00gzkxz88","country_code":"DE","type":"education","lineage":["https://openalex.org/I309496635"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Florian Goebels","raw_affiliation_strings":["Department of Genome Oriented Bioinformatics, Wissenschaftszentrum Weihenstephan, Maximus-von-Imhof-Forum 1, Freising, 85350, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genome Oriented Bioinformatics, Wissenschaftszentrum Weihenstephan, Maximus-von-Imhof-Forum 1, Freising, 85350, Germany","institution_ids":["https://openalex.org/I309496635"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060795824","display_name":"Dmitrij Frishman","orcid":"https://orcid.org/0000-0002-9006-4707"},"institutions":[{"id":"https://openalex.org/I309496635","display_name":"Weihenstephan-Triesdorf University of Applied Sciences","ror":"https://ror.org/00gzkxz88","country_code":"DE","type":"education","lineage":["https://openalex.org/I309496635"]},{"id":"https://openalex.org/I4210100097","display_name":"Institute of Bioinformatics and Systems Biology","ror":"https://ror.org/0127fwn18","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672","https://openalex.org/I4210100097"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Dmitrij Frishman","raw_affiliation_strings":["Department of Genome Oriented Bioinformatics, Wissenschaftszentrum Weihenstephan, Maximus-von-Imhof-Forum 1, Freising, 85350, Germany","HMGU German Research Center for Environmental Health, Institute for Bioinformatics and Systems Biology/MIPS, Ingolstadter Landstra\u00dfe 1, Neuherberg, 85764, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genome Oriented Bioinformatics, Wissenschaftszentrum Weihenstephan, Maximus-von-Imhof-Forum 1, Freising, 85350, Germany","institution_ids":["https://openalex.org/I309496635"]},{"raw_affiliation_string":"HMGU German Research Center for Environmental Health, Institute for Bioinformatics and Systems Biology/MIPS, Ingolstadter Landstra\u00dfe 1, Neuherberg, 85764, Germany","institution_ids":["https://openalex.org/I4210100097"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5060795824"],"corresponding_institution_ids":["https://openalex.org/I309496635","https://openalex.org/I4210100097"],"apc_list":null,"apc_paid":null,"fwci":0.8977,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.74750186,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"7","issue":"Suppl 6","first_page":"S5","last_page":"S5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.8313000202178955,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.8313000202178955,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.10890000313520432,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obligate","display_name":"Obligate","score":0.9115859866142273},{"id":"https://openalex.org/keywords/interaction-network","display_name":"Interaction network","score":0.5806885361671448},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.550596296787262},{"id":"https://openalex.org/keywords/protein\u2013protein-interaction","display_name":"Protein\u2013protein interaction","score":0.47422170639038086},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.45871785283088684},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.4479680061340332},{"id":"https://openalex.org/keywords/topology","display_name":"Topology (electrical circuits)","score":0.43643510341644287},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.4293188452720642},{"id":"https://openalex.org/keywords/network-topology","display_name":"Network topology","score":0.41969791054725647},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.4165460765361786},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3963180184364319},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2732087969779968},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.17421674728393555},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1448935568332672},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.11418551206588745},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.10653755068778992}],"concepts":[{"id":"https://openalex.org/C24990904","wikidata":"https://www.wikidata.org/wiki/Q7075144","display_name":"Obligate","level":2,"score":0.9115859866142273},{"id":"https://openalex.org/C55105296","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interaction network","level":3,"score":0.5806885361671448},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.550596296787262},{"id":"https://openalex.org/C11804247","wikidata":"https://www.wikidata.org/wiki/Q896177","display_name":"Protein\u2013protein interaction","level":2,"score":0.47422170639038086},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45871785283088684},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.4479680061340332},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.43643510341644287},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.4293188452720642},{"id":"https://openalex.org/C199845137","wikidata":"https://www.wikidata.org/wiki/Q145490","display_name":"Network topology","level":2,"score":0.41969791054725647},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.4165460765361786},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3963180184364319},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2732087969779968},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.17421674728393555},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1448935568332672},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.11418551206588745},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10653755068778992},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1752-0509-7-s6-s5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-7-s6-s5","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-7-S6-S5","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:24564924","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24564924","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:europepmc.org:3022827","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4029746","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:opus-zb.helmholtz-muenchen.de:28942","is_oa":true,"landing_page_url":"https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=28942","pdf_url":null,"source":{"id":"https://openalex.org/S4377196115","display_name":"Site cant be reached","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Syst. Biol. 7:S5 (2013)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/1752-0509-7-s6-s5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-7-s6-s5","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-7-S6-S5","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G622130035","display_name":null,"funder_award_id":"GRK 1563","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2123482512.pdf","grobid_xml":"https://content.openalex.org/works/W2123482512.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W229097380","https://openalex.org/W1486227877","https://openalex.org/W1515965683","https://openalex.org/W1879536506","https://openalex.org/W1926568554","https://openalex.org/W1980800453","https://openalex.org/W1981097590","https://openalex.org/W1987749411","https://openalex.org/W2003516452","https://openalex.org/W2012852001","https://openalex.org/W2015094506","https://openalex.org/W2015802360","https://openalex.org/W2016894211","https://openalex.org/W2024138709","https://openalex.org/W2037442572","https://openalex.org/W2042905169","https://openalex.org/W2043699100","https://openalex.org/W2045501270","https://openalex.org/W2065702910","https://openalex.org/W2075770210","https://openalex.org/W2078302553","https://openalex.org/W2082565035","https://openalex.org/W2088387316","https://openalex.org/W2091563009","https://openalex.org/W2094148990","https://openalex.org/W2097636810","https://openalex.org/W2098869926","https://openalex.org/W2100761975","https://openalex.org/W2102992354","https://openalex.org/W2103017472","https://openalex.org/W2103105682","https://openalex.org/W2112262143","https://openalex.org/W2114801649","https://openalex.org/W2116211027","https://openalex.org/W2117513900","https://openalex.org/W2121852482","https://openalex.org/W2122863289","https://openalex.org/W2123121534","https://openalex.org/W2123357765","https://openalex.org/W2128049108","https://openalex.org/W2130253098","https://openalex.org/W2130479394","https://openalex.org/W2130687290","https://openalex.org/W2131816626","https://openalex.org/W2136525667","https://openalex.org/W2138735135","https://openalex.org/W2142796125","https://openalex.org/W2143593035","https://openalex.org/W2143892509","https://openalex.org/W2144907278","https://openalex.org/W2148043260","https://openalex.org/W2148219066","https://openalex.org/W2150318080","https://openalex.org/W2158100564","https://openalex.org/W2158266097","https://openalex.org/W2165253681","https://openalex.org/W2171030481","https://openalex.org/W2911964244","https://openalex.org/W2916767477"],"related_works":["https://openalex.org/W4229728790","https://openalex.org/W2800059693","https://openalex.org/W2123482512","https://openalex.org/W2066232588","https://openalex.org/W2130123090","https://openalex.org/W4377086792","https://openalex.org/W2767490506","https://openalex.org/W1987705964","https://openalex.org/W2914490533","https://openalex.org/W1841073402"],"abstract_inverted_index":{"BACKGROUND:":[0],"Protein":[1],"interactions":[2,54,71,129,163,230,252],"mediate":[3],"a":[4,21,86,101,117,207,245,299],"wide":[5],"spectrum":[6],"of":[7,15,24,34,42,67,99,128,136,146,183,203,210,248,263],"functions":[8],"in":[9,105,236,260],"various":[10],"cellular":[11],"contexts.":[12],"Functional":[13],"versatility":[14],"protein":[16,70,147,162,291],"complexes":[17,205,255],"is":[18,242,274,294],"due":[19],"to":[20,48,222,257,287],"broad":[22],"range":[23],"structural":[25,211],"adaptations":[26],"that":[27,200],"determine":[28],"their":[29,192],"binding":[30,122,139,185],"affinity,":[31],"the":[32,38,60,83,94,106,109,120,134,137,184,201],"number":[33],"interaction":[35,224,240,280],"sites,":[36],"and":[37,52,168,177,195,217,228,273],"lifetime.":[39],"In":[40,65,82],"terms":[41,66],"stability":[43],"it":[44],"has":[45],"become":[46],"customary":[47],"distinguish":[49],"between":[50],"obligate":[51,176,223],"non-obligate":[53,204],"dependent":[55],"on":[56,133,270],"whether":[57],"or":[58,78],"not":[59,268],"protomers":[61],"can":[62,72,283],"exist":[63],"independently.":[64],"spatio-temporal":[68],"control":[69],"be":[73,258,285],"either":[74],"simultaneously":[75,165],"possible":[76,166],"(SP)":[77,167],"mutually":[79,169],"exclusive":[80,170],"(ME).":[81],"former":[84],"case":[85,108],"network":[87,196,237],"hub":[88,110],"interacts":[89,111],"with":[90,112,244],"several":[91],"proteins":[92],"at":[93,116],"same":[95,121],"time,":[96],"offering":[97],"each":[98],"them":[100],"separate":[102],"interface,":[103],"while":[104,226],"latter":[107],"its":[113],"partners":[114,186,225],"one":[115,261],"time":[118],"via":[119],"site.":[123],"So":[124],"far":[125],"different":[126],"types":[127],"were":[130],"distinguished":[131],"based":[132],"properties":[135],"corresponding":[138],"interfaces":[140],"derived":[141],"from":[142,188,302],"known":[143],"three-dimensional":[144],"structures":[145,272],"complexes.":[148,292],"RESULTS:":[149],"Here":[150],"we":[151],"present":[152],"PiType,":[153],"an":[154],"accurate":[155],"3D":[156],"structure-independent":[157],"computational":[158],"method":[159],"for":[160,277,296],"classifying":[161],"into":[164,175],"(ME)":[171],"as":[172,174,298],"well":[173],"non-obligate.":[178],"Our":[179],"classifier":[180],"exploits":[181],"features":[182],"predicted":[187],"amino":[189],"acid":[190],"sequence,":[191],"functional":[193,219],"similarity,":[194],"topology.":[197,238],"We":[198],"find":[199],"constituents":[202],"possess":[206],"higher":[208],"degree":[209],"disorder,":[212],"more":[213],"short":[214],"linear":[215],"motifs,":[216],"lower":[218],"similarity":[220],"compared":[221],"SP":[227],"ME":[229],"are":[231],"characterized":[232],"by":[233],"significant":[234],"differences":[235],"Each":[239],"type":[241,262],"associated":[243],"distinct":[246],"set":[247],"biological":[249],"functions.":[250],"Moreover,":[251],"within":[253,290],"multi-protein":[254],"tend":[256],"enriched":[259],"interactions.":[264],"CONCLUSION:":[265],"PiType":[266,293],"does":[267],"rely":[269],"atomic":[271],"thus":[275],"suitable":[276],"characterizing":[278],"proteome-wide":[279],"datasets.":[281],"It":[282],"also":[284],"used":[286],"identify":[288],"sub-modules":[289],"available":[295],"download":[297],"self-installing":[300],"package":[301],"http://webclu.bio.wzw.tum.de/PiType/PiType.zip.":[303]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2025-10-10T00:00:00"}