{"id":"https://openalex.org/W2171681747","doi":"https://doi.org/10.1186/1752-0509-7-107","title":"A novel untargeted metabolomics correlation-based network analysis incorporating human metabolic reconstructions","display_name":"A novel untargeted metabolomics correlation-based network analysis incorporating human metabolic reconstructions","publication_year":2013,"publication_date":"2013-10-23","ids":{"openalex":"https://openalex.org/W2171681747","doi":"https://doi.org/10.1186/1752-0509-7-107","mag":"2171681747","pmid":"https://pubmed.ncbi.nlm.nih.gov/24153255"},"language":"en","primary_location":{"id":"doi:10.1186/1752-0509-7-107","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-7-107","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-7-107","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-7-107","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055112499","display_name":"Helen L. Kotze","orcid":null},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Helen L Kotze","raw_affiliation_strings":["School of Chemical Engineering and Analytical Science, Manchester Institute of Biotechnology, University of Manchester, Manchester, M1 7DN, UK"],"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering and Analytical Science, Manchester Institute of Biotechnology, University of Manchester, Manchester, M1 7DN, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063003438","display_name":"Emily G. Armitage","orcid":"https://orcid.org/0000-0001-6948-3854"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Emily G Armitage","raw_affiliation_strings":["School of Chemical Engineering and Analytical Science, Manchester Institute of Biotechnology, University of Manchester, Manchester, M1 7DN, UK"],"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering and Analytical Science, Manchester Institute of Biotechnology, University of Manchester, Manchester, M1 7DN, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036813162","display_name":"Kieran J. Sharkey","orcid":"https://orcid.org/0000-0002-7210-9246"},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kieran J Sharkey","raw_affiliation_strings":["Department of Mathematical Sciences, The University of Liverpool, Peach Street, Liverpool, L69 7ZL, UK"],"affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences, The University of Liverpool, Peach Street, Liverpool, L69 7ZL, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036624366","display_name":"J. William Allwood","orcid":"https://orcid.org/0000-0001-6433-2694"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"James W Allwood","raw_affiliation_strings":["School of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester, M1 7DN, UK"],"affiliations":[{"raw_affiliation_string":"School of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester, M1 7DN, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091024912","display_name":"Warwick B. Dunn","orcid":"https://orcid.org/0000-0001-6924-0027"},"institutions":[{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210092852","display_name":"Manchester University NHS Foundation Trust","ror":"https://ror.org/00he80998","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210092852"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Warwick B Dunn","raw_affiliation_strings":["Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, York Place, off Oxford Road, Manchester, M13 9WL, UK","Centre for Endocrinology and Diabetes, Institute of Human Development, The University of Manchester, Manchester, M13 9PL, UK","School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK"],"affiliations":[{"raw_affiliation_string":"Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, York Place, off Oxford Road, Manchester, M13 9WL, UK","institution_ids":["https://openalex.org/I4210092852"]},{"raw_affiliation_string":"Centre for Endocrinology and Diabetes, Institute of Human Development, The University of Manchester, Manchester, M13 9PL, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK","institution_ids":["https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031947326","display_name":"Kaye J. Williams","orcid":"https://orcid.org/0000-0001-7708-3770"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kaye J Williams","raw_affiliation_strings":["Manchester Pharmacy School, University of Manchester, Oxford Road, Manchester, M13 9PT, UK"],"affiliations":[{"raw_affiliation_string":"Manchester Pharmacy School, University of Manchester, Oxford Road, Manchester, M13 9PT, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059684811","display_name":"Royston Goodacre","orcid":"https://orcid.org/0000-0003-2230-645X"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Royston Goodacre","raw_affiliation_strings":["School of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester M1 7DN, UK. roy.goodacre@manchester.ac.uk","School of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester, M1 7DN, UK"],"affiliations":[{"raw_affiliation_string":"School of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester M1 7DN, UK. roy.goodacre@manchester.ac.uk","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester, M1 7DN, UK","institution_ids":["https://openalex.org/I28407311"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5055112499"],"corresponding_institution_ids":["https://openalex.org/I28407311"],"apc_list":null,"apc_paid":null,"fwci":3.5935,"has_fulltext":true,"cited_by_count":77,"citation_normalized_percentile":{"value":0.93689571,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"7","issue":"1","first_page":"107","last_page":"107"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metabolomics","display_name":"Metabolomics","score":0.761378288269043},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.7575099468231201},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6444836258888245},{"id":"https://openalex.org/keywords/metabolic-network","display_name":"Metabolic network","score":0.5056300163269043},{"id":"https://openalex.org/keywords/biological-network","display_name":"Biological network","score":0.4640136957168579},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.45674365758895874},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.45355090498924255},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.2960417866706848}],"concepts":[{"id":"https://openalex.org/C21565614","wikidata":"https://www.wikidata.org/wiki/Q12149006","display_name":"Metabolomics","level":2,"score":0.761378288269043},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.7575099468231201},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6444836258888245},{"id":"https://openalex.org/C101810790","wikidata":"https://www.wikidata.org/wiki/Q2263094","display_name":"Metabolic network","level":2,"score":0.5056300163269043},{"id":"https://openalex.org/C28225019","wikidata":"https://www.wikidata.org/wiki/Q4915005","display_name":"Biological network","level":2,"score":0.4640136957168579},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.45674365758895874},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45355090498924255},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2960417866706848}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D045325","descriptor_name":"HCT116 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045325","descriptor_name":"HCT116 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045325","descriptor_name":"HCT116 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045325","descriptor_name":"HCT116 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1186/1752-0509-7-107","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-7-107","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-7-107","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:24153255","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24153255","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/90a6b7b8-3a8b-44e5-a27e-a756190e5e55","is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/90a6b7b8-3a8b-44e5-a27e-a756190e5e55","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kotze, H L, Armitage, E G, Sharkey, K J, Allwood, J W, Dunn, W B, Williams, K J & Goodacre, R 2013, 'A novel untargeted metabolomics correlation-based network analysis incorporating human metabolic reconstructions', BMC Systems Biology, vol. 7, 107. https://doi.org/10.1186/1752-0509-7-107","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:eprints.gla.ac.uk:123027","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4210235606","display_name":"ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)","issn_l":"2622-8912","issn":["2622-8912","2622-8920"],"is_oa":false,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Articles"},{"id":"pmh:oai:pubmedcentral.nih.gov:3874763","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3874763","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Syst Biol","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/0fda114e-7105-4942-bf26-25d8b6d7feba","is_oa":true,"landing_page_url":"https://research.birmingham.ac.uk/en/publications/0fda114e-7105-4942-bf26-25d8b6d7feba","pdf_url":null,"source":{"id":"https://openalex.org/S4306402634","display_name":"University of Birmingham Research Portal (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Kotze, H L, Armitage, E G, Sharkey, K J, Allwood, J W, Dunn, W B, Williams, K J & Goodacre, R 2013, 'A novel untargeted metabolomics correlation-based network analysis incorporating human metabolic reconstructions', BMC systems biology, vol. 7, 107. https://doi.org/10.1186/1752-0509-7-107","raw_type":"article"},{"id":"pmh:oai:pure.atira.dk:publications/90a6b7b8-3a8b-44e5-a27e-a756190e5e55","is_oa":false,"landing_page_url":"https://www.research.manchester.ac.uk/portal/en/publications/a-novel-untargeted-metabolomics-correlationbased-network-analysis-incorporating-human-metabolic-reconstructions(90a6b7b8-3a8b-44e5-a27e-a756190e5e55).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Kotze, H L, Armitage, E G, Sharkey, K J, Allwood, J W, Dunn, W B, Williams, K J & Goodacre, R 2013, 'A novel untargeted metabolomics correlation-based network analysis incorporating human metabolic reconstructions', BMC Systems Biology, vol. 7, 107. https://doi.org/10.1186/1752-0509-7-107","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1186/1752-0509-7-107","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-7-107","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-7-107","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7099999785423279}],"awards":[{"id":"https://openalex.org/G2285713050","display_name":null,"funder_award_id":"BBC0082191","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G3523403592","display_name":null,"funder_award_id":"Engineering and Physical Research Council","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G7251638025","display_name":null,"funder_award_id":"BBC0082191","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2171681747.pdf","grobid_xml":"https://content.openalex.org/works/W2171681747.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W166944394","https://openalex.org/W1502402983","https://openalex.org/W1611854178","https://openalex.org/W1900380445","https://openalex.org/W1976672440","https://openalex.org/W1978346875","https://openalex.org/W1986517285","https://openalex.org/W1993323132","https://openalex.org/W2017752147","https://openalex.org/W2023535481","https://openalex.org/W2031190866","https://openalex.org/W2036181747","https://openalex.org/W2047632644","https://openalex.org/W2060592426","https://openalex.org/W2062533676","https://openalex.org/W2072451938","https://openalex.org/W2081010896","https://openalex.org/W2089468765","https://openalex.org/W2092787533","https://openalex.org/W2100452303","https://openalex.org/W2101291628","https://openalex.org/W2104108767","https://openalex.org/W2108859156","https://openalex.org/W2113952909","https://openalex.org/W2128307328","https://openalex.org/W2132218677","https://openalex.org/W2137128504","https://openalex.org/W2139301359","https://openalex.org/W2140181854","https://openalex.org/W2149517485","https://openalex.org/W2149606140","https://openalex.org/W2149617981","https://openalex.org/W2151346683","https://openalex.org/W2163841023","https://openalex.org/W2423710301","https://openalex.org/W3099514962","https://openalex.org/W4235947997","https://openalex.org/W4236706032","https://openalex.org/W4239632189"],"related_works":["https://openalex.org/W2799517538","https://openalex.org/W2154631167","https://openalex.org/W2152476191","https://openalex.org/W2166430819","https://openalex.org/W2158714033","https://openalex.org/W2072067873","https://openalex.org/W78967844","https://openalex.org/W5284979","https://openalex.org/W2047632644","https://openalex.org/W2133150343"],"abstract_inverted_index":{"Metabolic":[0],"networks":[1],"generated":[2],"for":[3],"each":[4],"cell":[5],"line":[6],"were":[7],"compared":[8],"to":[9,15],"identify":[10],"conserved":[11],"metabolite":[12],"pathway":[13],"responses":[14],"low":[16],"oxygen":[17],"environments.":[18],"Furthermore,":[19],"we":[20],"believe":[21],"this":[22],"methodology":[23],"will":[24],"have":[25],"general":[26],"application":[27],"within":[28],"metabolomics.":[29]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":10}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}