{"id":"https://openalex.org/W2134892427","doi":"https://doi.org/10.1186/1752-0509-5-116","title":"iRsp1095: A genome-scale reconstruction of the Rhodobacter sphaeroides metabolic network","display_name":"iRsp1095: A genome-scale reconstruction of the Rhodobacter sphaeroides metabolic network","publication_year":2011,"publication_date":"2011-07-21","ids":{"openalex":"https://openalex.org/W2134892427","doi":"https://doi.org/10.1186/1752-0509-5-116","mag":"2134892427"},"language":"en","primary_location":{"id":"doi:10.1186/1752-0509-5-116","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-5-116","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-5-116","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-5-116","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079737505","display_name":"Saheed Imam","orcid":"https://orcid.org/0000-0001-7508-5887"},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]},{"id":"https://openalex.org/I2801044051","display_name":"Great Lakes Bioenergy Research Center","ror":"https://ror.org/01ca2by25","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I2801044051"]},{"id":"https://openalex.org/I2802999273","display_name":"Wisconsin Institutes for Discovery","ror":"https://ror.org/05gbven85","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2802999273"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saheed Imam","raw_affiliation_strings":["BACTER Institute, University of Wisconsin, Madison, USA","DOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, USA","Program in Cellular and Molecular Biology, University of Wisconsin, Madison, USA"],"affiliations":[{"raw_affiliation_string":"BACTER Institute, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I2802999273"]},{"raw_affiliation_string":"DOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I2801044051","https://openalex.org/I135310074"]},{"raw_affiliation_string":"Program in Cellular and Molecular Biology, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103503768","display_name":"\u015eafak Y\u0131lmaz","orcid":null},"institutions":[{"id":"https://openalex.org/I2801044051","display_name":"Great Lakes Bioenergy Research Center","ror":"https://ror.org/01ca2by25","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I2801044051"]},{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Safak Yilmaz","raw_affiliation_strings":["DOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, USA","Department of Civil and Environmental Engineering, University of Wisconsin, Madison, USA"],"affiliations":[{"raw_affiliation_string":"DOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I2801044051","https://openalex.org/I135310074"]},{"raw_affiliation_string":"Department of Civil and Environmental Engineering, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034201431","display_name":"Ugur Sohmen","orcid":null},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ugur Sohmen","raw_affiliation_strings":["Department of Civil and Environmental Engineering, University of Wisconsin, Madison, USA"],"affiliations":[{"raw_affiliation_string":"Department of Civil and Environmental Engineering, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039690481","display_name":"Alexander S. Gorzalski","orcid":"https://orcid.org/0000-0001-8278-0538"},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander S Gorzalski","raw_affiliation_strings":["Department of Civil and Environmental Engineering, University of Wisconsin, Madison, USA"],"affiliations":[{"raw_affiliation_string":"Department of Civil and Environmental Engineering, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059438505","display_name":"Jennifer L. Reed","orcid":"https://orcid.org/0000-0001-7854-6220"},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]},{"id":"https://openalex.org/I2801044051","display_name":"Great Lakes Bioenergy Research Center","ror":"https://ror.org/01ca2by25","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I2801044051"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer L Reed","raw_affiliation_strings":["Chemical and Biological Engineering Department, University of Wisconsin, Madison, USA","DOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, USA"],"affiliations":[{"raw_affiliation_string":"Chemical and Biological Engineering Department, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I135310074"]},{"raw_affiliation_string":"DOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I2801044051","https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020842663","display_name":"Daniel R. Noguera","orcid":"https://orcid.org/0000-0003-0372-3063"},"institutions":[{"id":"https://openalex.org/I2801044051","display_name":"Great Lakes Bioenergy Research Center","ror":"https://ror.org/01ca2by25","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I2801044051"]},{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel R Noguera","raw_affiliation_strings":["DOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, USA","Department of Civil and Environmental Engineering, University of Wisconsin, Madison, USA"],"affiliations":[{"raw_affiliation_string":"DOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I2801044051","https://openalex.org/I135310074"]},{"raw_affiliation_string":"Department of Civil and Environmental Engineering, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045417376","display_name":"Timothy J. Donohue","orcid":"https://orcid.org/0000-0001-8738-2467"},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]},{"id":"https://openalex.org/I2801044051","display_name":"Great Lakes Bioenergy Research Center","ror":"https://ror.org/01ca2by25","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I2801044051"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Timothy J Donohue","raw_affiliation_strings":["DOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, USA","Department of Bacteriology, University of Wisconsin - Madison, 5159 Microbial Sciences Building, 1550 Linden Drive, Madison, WI, 53706, USA"],"affiliations":[{"raw_affiliation_string":"DOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, USA","institution_ids":["https://openalex.org/I2801044051","https://openalex.org/I135310074"]},{"raw_affiliation_string":"Department of Bacteriology, University of Wisconsin - Madison, 5159 Microbial Sciences Building, 1550 Linden Drive, Madison, WI, 53706, USA","institution_ids":["https://openalex.org/I135310074"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5045417376"],"corresponding_institution_ids":["https://openalex.org/I135310074","https://openalex.org/I2801044051"],"apc_list":null,"apc_paid":null,"fwci":2.935,"has_fulltext":true,"cited_by_count":79,"citation_normalized_percentile":{"value":0.91667623,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"5","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10476","display_name":"Algal biology and biofuel production","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2105","display_name":"Renewable Energy, Sustainability and the Environment"},"field":{"id":"https://openalex.org/fields/21","display_name":"Energy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rhodobacter-sphaeroides","display_name":"Rhodobacter sphaeroides","score":0.9713525772094727},{"id":"https://openalex.org/keywords/phototroph","display_name":"Phototroph","score":0.8870007991790771},{"id":"https://openalex.org/keywords/flux-balance-analysis","display_name":"Flux balance analysis","score":0.678308367729187},{"id":"https://openalex.org/keywords/photosynthesis","display_name":"Photosynthesis","score":0.6722564697265625},{"id":"https://openalex.org/keywords/metabolic-engineering","display_name":"Metabolic engineering","score":0.6156126856803894},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5430734157562256},{"id":"https://openalex.org/keywords/rhodospirillaceae","display_name":"Rhodospirillaceae","score":0.5339314937591553},{"id":"https://openalex.org/keywords/carbon-fixation","display_name":"Carbon fixation","score":0.5263584852218628},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4894980192184448},{"id":"https://openalex.org/keywords/rhodobacter","display_name":"Rhodobacter","score":0.4889916181564331},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.42353302240371704},{"id":"https://openalex.org/keywords/biomass","display_name":"Biomass (ecology)","score":0.41363003849983215},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4126124382019043},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3747676908969879},{"id":"https://openalex.org/keywords/botany","display_name":"Botany","score":0.2556348145008087},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.2518938183784485},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.1738981008529663},{"id":"https://openalex.org/keywords/mutant","display_name":"Mutant","score":0.12158334255218506}],"concepts":[{"id":"https://openalex.org/C2777897970","wikidata":"https://www.wikidata.org/wiki/Q4186823","display_name":"Rhodobacter sphaeroides","level":3,"score":0.9713525772094727},{"id":"https://openalex.org/C197322856","wikidata":"https://www.wikidata.org/wiki/Q335183","display_name":"Phototroph","level":3,"score":0.8870007991790771},{"id":"https://openalex.org/C167091322","wikidata":"https://www.wikidata.org/wiki/Q5463029","display_name":"Flux balance analysis","level":2,"score":0.678308367729187},{"id":"https://openalex.org/C183688256","wikidata":"https://www.wikidata.org/wiki/Q11982","display_name":"Photosynthesis","level":2,"score":0.6722564697265625},{"id":"https://openalex.org/C6350086","wikidata":"https://www.wikidata.org/wiki/Q6822347","display_name":"Metabolic engineering","level":3,"score":0.6156126856803894},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5430734157562256},{"id":"https://openalex.org/C2779291864","wikidata":"https://www.wikidata.org/wiki/Q24301","display_name":"Rhodospirillaceae","level":3,"score":0.5339314937591553},{"id":"https://openalex.org/C199873434","wikidata":"https://www.wikidata.org/wiki/Q901921","display_name":"Carbon fixation","level":3,"score":0.5263584852218628},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4894980192184448},{"id":"https://openalex.org/C2777850835","wikidata":"https://www.wikidata.org/wiki/Q3016950","display_name":"Rhodobacter","level":4,"score":0.4889916181564331},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.42353302240371704},{"id":"https://openalex.org/C115540264","wikidata":"https://www.wikidata.org/wiki/Q2945560","display_name":"Biomass (ecology)","level":2,"score":0.41363003849983215},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4126124382019043},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3747676908969879},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.2556348145008087},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2518938183784485},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.1738981008529663},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.12158334255218506}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1186/1752-0509-5-116","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-5-116","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-5-116","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2159790","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3152904","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1752-0509-5-116","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-5-116","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-5-116","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1052503337","display_name":null,"funder_award_id":"FC02-07ER64494","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G1354517864","display_name":"BACTER: BRINGING ADVANCED COMPUTATIONAL TECHNIQUES TO ENVIRONMENTAL RESEARCH","funder_award_id":"FG02-04ER25627","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G222180108","display_name":null,"funder_award_id":"07ER64494","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G23300722","display_name":null,"funder_award_id":"DE-FC02-07ER64494","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G2939438446","display_name":null,"funder_award_id":"DE-FG02-04ER25627","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G3193070969","display_name":null,"funder_award_id":"DE-FC02-07ER64494","funder_id":"https://openalex.org/F4320337509","funder_display_name":"Biological and Environmental Research"},{"id":"https://openalex.org/G3909856062","display_name":null,"funder_award_id":"DE-FG02-07ER64495","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G4063130707","display_name":null,"funder_award_id":"DE-FC02-07ER64494","funder_id":"https://openalex.org/F4320332359","funder_display_name":"Office of Science"},{"id":"https://openalex.org/G4385836085","display_name":null,"funder_award_id":"FC02-07ER64494","funder_id":"https://openalex.org/F4320332359","funder_display_name":"Office of Science"},{"id":"https://openalex.org/G5219260752","display_name":null,"funder_award_id":"DE-FG","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G6299481046","display_name":null,"funder_award_id":"DE-FC02-07ER64494","funder_id":"https://openalex.org/F4320333880","funder_display_name":"Great Lakes Bioenergy Research Center"},{"id":"https://openalex.org/G7186324567","display_name":null,"funder_award_id":"DE-FG02-","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G7335514663","display_name":"NETWORKS IMPACTING SOLAR POWERED HYDROGEN PRODUCTION","funder_award_id":"FG02-07ER64495","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G8344606036","display_name":null,"funder_award_id":"SciDAC","funder_id":"https://openalex.org/F4320332359","funder_display_name":"Office of Science"},{"id":"https://openalex.org/G8684078510","display_name":null,"funder_award_id":"DE-FG02","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"}],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320332359","display_name":"Office of Science","ror":"https://ror.org/00mmn6b08"},{"id":"https://openalex.org/F4320333880","display_name":"Great Lakes Bioenergy Research Center","ror":"https://ror.org/01ca2by25"},{"id":"https://openalex.org/F4320337509","display_name":"Biological and Environmental Research","ror":"https://ror.org/0114b2m14"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2134892427.pdf","grobid_xml":"https://content.openalex.org/works/W2134892427.grobid-xml"},"referenced_works_count":66,"referenced_works":["https://openalex.org/W140841319","https://openalex.org/W1528660464","https://openalex.org/W1592200047","https://openalex.org/W1775749144","https://openalex.org/W1792091681","https://openalex.org/W1920971969","https://openalex.org/W1951911584","https://openalex.org/W1958003157","https://openalex.org/W1963202016","https://openalex.org/W1977278646","https://openalex.org/W1983120620","https://openalex.org/W1984345785","https://openalex.org/W1990428308","https://openalex.org/W1992638962","https://openalex.org/W1995856461","https://openalex.org/W1999066586","https://openalex.org/W2003709444","https://openalex.org/W2009990638","https://openalex.org/W2013864976","https://openalex.org/W2014281089","https://openalex.org/W2016423374","https://openalex.org/W2019943013","https://openalex.org/W2025547877","https://openalex.org/W2025663053","https://openalex.org/W2029403511","https://openalex.org/W2033034080","https://openalex.org/W2033268087","https://openalex.org/W2033506551","https://openalex.org/W2038080013","https://openalex.org/W2045746506","https://openalex.org/W2047228180","https://openalex.org/W2051445229","https://openalex.org/W2056281205","https://openalex.org/W2060809347","https://openalex.org/W2062245653","https://openalex.org/W2062382569","https://openalex.org/W2070048993","https://openalex.org/W2075228038","https://openalex.org/W2076163024","https://openalex.org/W2076262841","https://openalex.org/W2081192589","https://openalex.org/W2083011190","https://openalex.org/W2085993965","https://openalex.org/W2089449076","https://openalex.org/W2095908454","https://openalex.org/W2098824895","https://openalex.org/W2099995274","https://openalex.org/W2102164505","https://openalex.org/W2111102591","https://openalex.org/W2114124738","https://openalex.org/W2115928708","https://openalex.org/W2117741404","https://openalex.org/W2117913657","https://openalex.org/W2119785097","https://openalex.org/W2125760935","https://openalex.org/W2135961556","https://openalex.org/W2140000393","https://openalex.org/W2141266374","https://openalex.org/W2144571395","https://openalex.org/W2150619924","https://openalex.org/W2155606054","https://openalex.org/W2160541874","https://openalex.org/W2162215524","https://openalex.org/W2163240970","https://openalex.org/W2170427655","https://openalex.org/W4248664566"],"related_works":["https://openalex.org/W1994237025","https://openalex.org/W2029927227","https://openalex.org/W2889721066","https://openalex.org/W2005116531","https://openalex.org/W4254199133","https://openalex.org/W2075069510","https://openalex.org/W2015205953","https://openalex.org/W2090318613","https://openalex.org/W2533069411","https://openalex.org/W2086562941"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Rhodobacter":[2],"sphaeroides":[3,39,109,125,168,255],"is":[4],"one":[5],"of":[6,23,29,37,82,88,115,166,180,218,247],"the":[7,21,26,216,242],"best":[8],"studied":[9],"purple":[10],"non-sulfur":[11],"photosynthetic":[12],"bacteria":[13],"and":[14,25,31,120,148,244,249,256],"serves":[15],"as":[16,51,53,64],"an":[17,73,170],"excellent":[18,74],"model":[19,106],"for":[20,76,107,153,173,235],"study":[22],"photosynthesis":[24],"metabolic":[27,90,104,237],"capabilities":[28,91],"this":[30,95,131,198,219],"related":[32,258],"facultative":[33],"organisms.":[34,259],"The":[35],"ability":[36,55],"R.":[38,108,124,167,254],"to":[40,56,224,240],"produce":[41],"hydrogen":[42],"(H":[43],"2":[44,62,175,183],"),":[45],"polyhydroxybutyrate":[46],"(PHB)":[47],"or":[48],"other":[49,250],"hydrocarbons,":[50],"well":[52,139],"its":[54,89],"utilize":[57],"atmospheric":[58],"carbon":[59,66],"dioxide":[60],"(CO":[61],")":[63],"a":[65,79,102,232],"source":[67],"under":[68,146],"defined":[69],"conditions,":[70],"make":[71],"it":[72],"candidate":[75],"use":[77],"in":[78,130],"wide":[80],"variety":[81],"biotechnological":[83,96],"applications.":[84],"A":[85],"genome-level":[86],"understanding":[87],"should":[92],"help":[93],"realize":[94],"potential.":[97],"Results":[98],"Here":[99],"we":[100],"present":[101],"genome-scale":[103],"network":[105],"strain":[110],"2.4.1,":[111],"designated":[112],"iRsp1095,":[113],"consisting":[114],"1,095":[116],"genes,":[117],"796":[118],"metabolites":[119],"1158":[121],"reactions,":[122],"including":[123],"-specific":[126],"biomass":[127],"reactions":[128],"developed":[129],"study.":[132],"Constraint-based":[133],"analysis":[134],"showed":[135],"that":[136,188,204,213],"iRsp1095":[137,186,230],"agreed":[138],"with":[140,197],"experimental":[141],"observations":[142],"when":[143],"modeling":[144],"growth":[145,155],"respiratory":[147],"phototrophic":[149,154],"conditions.":[150],"Genes":[151],"essential":[152],"were":[156,222],"predicted":[157,199],"by":[158,253],"single":[159],"gene":[160],"deletion":[161],"analysis.":[162],"During":[163],"pathway-level":[164],"analyses":[165],"metabolism,":[169],"alternative":[171],"route":[172],"CO":[174],"assimilation":[176],"was":[177],"identified.":[178],"Evaluation":[179],"photoheterotrophic":[181],"H":[182],"production":[184,246],"using":[185],"indicated":[187],"maximal":[189],"yield":[190],"would":[191],"be":[192],"obtained":[193],"from":[194,207],"growing":[195],"cells,":[196],"maximum":[200,221],"~50%":[201],"higher":[202],"than":[203],"observed":[205],"experimentally":[206],"wild":[208],"type":[209],"cells.":[210],"Competing":[211],"pathways":[212],"might":[214],"prevent":[215],"achievement":[217],"theoretical":[220],"identified":[223],"guide":[225],"future":[226,236],"genetic":[227],"studies.":[228],"Conclusions":[229],"provides":[231],"robust":[233],"framework":[234],"engineering":[238],"efforts":[239],"optimize":[241],"solar-":[243],"nutrient-powered":[245],"biofuels":[248],"valuable":[251],"products":[252],"closely":[257]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":8}],"updated_date":"2026-04-14T08:04:32.555800","created_date":"2025-10-10T00:00:00"}
